immune system cells

IMMUNE SYSTEM CELLS

Unit 5-5 NotesMr. Hefti – Pulaski Biology

Blood Review

Type of cell Function Location

Macrophage Ingests pathogens Spleen, lungs, blood

Neutrophil Engulfs / destroys pathogens Bloodstream

Natural killer cell

Punctures infected cells Infected cells

Helper T cell Activates B cells and Cytotoxic T cells

Bloodstream

Cytotoxic T cell

Punctures infected cells Infection sites

B cell Forms plasma cells Infection sites

Plasma cell Releases antibodies Bloodstream

Memory cell Protects against defeated pathogens

Bloodstream

Immune response steps…1. Antigen triggers IR2. Macrophage “swallows”

pathogen3. Helper T and B cells

activated4. Antibodies bind to antigen

marking cell for destruction5. Cytotoxic T destroys marked

cells

Refer to

Tiger p. 936 to

label!

Virus

Viral antigen

Macrophage

Viral antigen

Helper T cellReceptor

proteins

Cytotoxic T cell

B cell

Plasma cell

Infected body cells

Antibodies

Viruses

Viral antigen

Receptor proteinAntibody

How do vaccines work? Immune system exposed to

weakened or harmless version of pathogen

Antibody production stimulated prior to actual exposure

BBC video clip

Type of cell Function Location

Macrophage Spleen, lungs, blood

Neutrophil Engulfs / destroys pathogens

Punctures infected cells Infected cells

Helper T cell Activates B cells and Cytotoxic T cells

Bloodstream

Punctures infected cells Infection sites

B cell Forms plasma cells

Plasma cell

Protects against defeated pathogens

Bloodstream

Type of cell Function Location

Macrophage Spleen, lungs, blood

Neutrophil Engulfs / destroys pathogens

Punctures infected cells Infected cells

Helper T cell Activates B cells and Cytotoxic T cells

Bloodstream

Punctures infected cells Infection sites

B cell Forms plasma cells

Plasma cell

Protects against defeated pathogens

Bloodstream

Type of cell Function Location

Macrophage Spleen, lungs, blood

Neutrophil Engulfs / destroys pathogens

Punctures infected cells Infected cells

Helper T cell Activates B cells and Cytotoxic T cells

Bloodstream

Punctures infected cells Infection sites

B cell Forms plasma cells

Plasma cell

Protects against defeated pathogens

Bloodstream

Type of cell Function Location

Macrophage Spleen, lungs, blood

Neutrophil Engulfs / destroys pathogens

Punctures infected cells Infected cells

Helper T cell Activates B cells and Cytotoxic T cells

Bloodstream

Punctures infected cells Infection sites

B cell Forms plasma cells

Plasma cell

Protects against defeated pathogens

Bloodstream