hepatitis b: a few facts - vaxxed · 2017. 4. 12. · hepatitis b vaccines hamza 2012 pmid:...

HepatitisB:afewfacts

SuzanneHumphries,MDVAXXEDtour2017

h"ps://www.gov.uk/government/publica8ons/vaccine-update-issue-261-april-2017

DrBonnieDunbarVerbaltestimony:USASenate1999

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IhavebeenhonoredbytheNationalInstitutesofHealthasthe5irstMargaretPittmanlecturerformypioneeringworkinvaccinedevelopment….

Iwouldchallengeanycolleague,clinicianorresearchscientist

toclaimthatwehaveabasicunderstandingofthehumannewbornimmunesystem.Itiswellestablishedinstudiesinanimalmodelsthatthenewbornimmunesystemisverydistinctfromtheadolescentoradult.Infact,theimmune

systemofnewbornsinanimalmodelscaneasilybeperturbedtoensurethatitcannotrespondproperlylaterinlife….

DrBonnieDunbaronautoimmunity:

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Anypeptide(alimitedsequenceofaminoacidsofaprotein)orafulllengthortruncatedprotein(producedby

puri5icationfromabiologicalsourceorusingrecombinantcDNAtechnology)whenintroducedintothebodywillbe"processedbytheimmunesystem"and,dependingonthe

natureofthatprotein,couldresultinlongtermautoimmunereactions.

DrDunbaronHepBvaccineresearch:

•  It is well documented …that committee members advising the CDC and members of organizations (such as the American Academy of Pediatrics, and the World Health Organization) obtain substantial funding from pharmaceutical companies.

•  Furthermore, it is well documented that investigators who have carried out clinical trials on this vaccine also benefit personally and obtain laboratory funding as consultants promoting the vaccine and as expert witness in legal conflicts.

DrDunbaronHepBvaccineresearch:•  It is also documented that lobbyists who consult for pharmaceutical

companies are the same lobbyists for medical health care providers. I leave it up to this distinguished committee to investigate and evaluate the seriousness of these apparent conflicts of interest.  

•  However, it is also apparent to me that the lack of government funding specified for independent scientists to evaluate adverse vaccine reactions is a major reason for scientists to seek funding for experiments dictated by pharmaceutical companies.

•  …adequate long-term follow-up information was not collected in clinical trials for this vaccine.

DrDunbar:prevaccineerarisk

Comparedwith...Ø  The P.I. has obtained from the FDA a list of adverse reactions reported for

Merck's Recombix HB vaccine from 1990 through part of 1996. Over 7000 adverse reactions are listed. (1200 per year)

Ø  It has been informally estimated that there may actually be uprwards of 30,000 adverse reaction reports for both the Merck Recombivax and the Smith KlineEngerix vaccines. (5000 per year)

Ø  Because the FDA reports that these adverse reactions constitute only 10% of adverse reactions, it can be assumed that there may be tens of thousands, if not hundreds of thousands of adverse reactions to these vaccines to date. (50,000 per year?)

Epigeneticmechanisms

Whatisepigeneticmodulation?

•  Allofushave“publicspeciLicities”

•  Buteachindividualisunique.•  Whatmakesthedifferenceareindividual“privatespeciLicities”–  PrivatespeciLicitiesinvolvethousandsofvariousgenesturnedonoroff.

Gil2015PMID:25573110

Ø  Two-folddeathincreaseintheonlycommunitystudyoftheintroduc8on•  ofDTP(Aaby2004PMID:15082643)

Ø  Three-folddecreaseinhospitalcasedeathwhenDTPwasnotgiven•  (Aaby2004PMID:15297050)

Ø  Four-folddeathincreasewhenDTPgivenaPerBCGinatrialofearlyBCG•  vaccina8ontoLBWchildren(Aaby2012PMID:22331681)

Ø  Two-folddeathincreasewhenDTPwasadministeredaPerHTMV (Aaby2003PMID:12842371)

AfricaDTPsnega8veeffects

Ø  Re-evalua6onofdatafrom1981to1983:1,057childrenØ ComparedtounvaccinatedØ DPT+OPVHazardra8oof5.0Ø DPTalone,noOPV–hazardra8oof10.0

AfricaDTPsnega8veeffectsII

Mogensen/Aaby2017PMID:28188123

Dovaccinesreallysavelives?

“AllcurrentlyavailableevidencesuggeststhatDTPvaccinemaykillmorechildrenfromothercausesthanit

savesfromdiphtheria,tetanus,orpertussis.”

Mogensen/Aaby2017PMID:28188123

M  GeneticdisordersM  CelldeathM  GIdiseaseM  DevelopmentaldisordersM  Metabolism(drugorfood)

M  CardiovasculardiseaseM  ImmunologicaldiseaseM  ConnectivetissuedisordersM  CellsignalingM  Energyproduction

Orntoft 2013 PMID: 23668887

! DPT vaccine effects:

Epigenetic modulation

InfantsafterDTaP-polio-Hibat3and5months

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PBMC stimulated with pertussis toxin:

12 hours later …

Lahdenpera, 2008. PMID: 18336961

¥ 33allergy-relatedgenesactivated

¥ 66asthmarelatedgenesactivated

¥ 67cancergeneswereup-regulated

¥ 25immunologicaldiseasegenesup-reg

HepatitisBvaccines

Hamza2012PMID:21691704

“HepatitisBvaccineshaveseveralsideeffectsthatarecausedbythealuminumadjuvant...Wecon5irmedby

quantitativeRT-PCRthathepatitisBvaccinechangedtheexpressionlevelofsevengenesthatwereselectedbiomarkers,whichre5lectedsubtoxic/adverseeffectsofthevaccine,especiallysubtleliver

injury.”

u MiceinjectedwithrecombHepBvaccine" 144livergeneschangedafteroneday

" 52downregulated,92upregulatedu 7werecloselyexamined

Ý 2inLlammationgenesupregulatedÝ 2acutephaseinLlammationproteinsupregÝ 1forgluconeogenesisupregulatedÞ 2forbileacidsynthesisdownregulated

Hamza2012PMID:21691704

AluminiumHepBvaccineeffects

•  6,399childrengotMV•  876childrengotMVand3dosesofHepBvaccine•  Followedto2yrsofage•  MVonlybutnoHBV:MR=0.97•  HBVplusMVcomparedtoMVonly

–  @7½monthsshorttermMR=1.62–  @7½-12months,MRwas1.81–  female:maleMR2.20

Garly2004PMID:15626943

2004Guinea-BissauHepBvaccinestudy

•  225USAinfantsgivenHepBvaccinedifferentdosestoseeiftheywouldrespondbettertoonedosevsanother

•  Infantswhoreceived10mcgdoseshadstatisticallysigni@icantgrowthretardation.(anotherNSE)–  Growthandweightdata(beforeandafter)almostneverreportedininfantvaccinestudies.

Coberly1996PMID:7975851

USA:HepBvaccinein1996

M “Theimmunologicalexplanationforthenon-speci@iceffectsofvaccinesisnotknownat

present.”

Orntoft 2013 PMID: 23668887

Geneexpressionchanges:justanothernonspeciLicsideeffect

VaccineViralEscape

FromaCDCscientist

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