emka technologies - isolated organs - emkabath4 tissue bath system

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emkaBATH4tissue bath system

1 - what is the emkaBATH4 system? APPLICATIONS SYSTEM OVERVIEW

2 - how does it work?AUTOMATIONSTAND-ALONE USE OR SOFTWARE CONTROLDATA ACQUISITIONSTIMULATION

3 - why use it?

what is the emkaBATH4 system?

aortic rings

trachea

papillary muscles

atrium

uterus

...

integrated and compact solution for studying the contractile properties of isolated tissue

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all-in-one mainframe

• 4 baths with transducers & amplifiers

• bath temperatures adjusted and

controlled electronically

• automated bath filling/emptying

• automated tissue tensioning with

motors

what is the emkaBATH4 system?

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integrated hardware

• pump for pushing perfusate to baths

• emptying pump for drawing perfusate

from the baths

what is the emkaBATH4 system?

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integrated hardware

• motors for tissue tensioning

• heating elements

• signal amplifiers

what is the emkaBATH4 system?

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the emkaBATH4 mainframe comes with:

• a power supply unit

• a perfusate reservoir

• container for used perfusate

what is the emkaBATH4 system?

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large range of hooks designed to facilitate tissue manipulation

range of bath sizes• 20ml• 10ml • 5ml

what is the emkaBATH4 system?

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custom-designed it50 isometric transducers

• robustness

• sensitivity

what is the emkaBATH4 system?

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custom-designed it50 isometric transducers

• stainless steel body

• 0-50 g (0 - 0.5 N) measuring range• displacement: 0.89 mm/50g• sensitivity@Vcc=5V: 0.1 mV/g

what is the emkaBATH4 system?

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microvessel study

• easily adapted for the study of up to 4 microvessels

• for vessels of diameter 100μm to 3 mm and up to 3.5mm long• each microvessel bath incorporates its own isometric transducer, measuring forces up to 30g

what is the emkaBATH4 system?

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mainframe control panel provides access to all operations

• set temperature : perfusate is heated to the required temperature as it travels to the bath• calibration : 0-1g / 0-10g / 0-50g

how does it work?

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mainframe control panel provides access to all operations

• set tension

(automated but manual override always

possible)

• fill, empty bath

• wash, renew bath

how does it work?

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data acquisition with iox or other data acquisition software

• USB connection to PC running iox software

• information displayed on the control panel is sent to iox (temperature, tissue tension)

• protocols can also be exported from iox

• BNC outputs provide calibrated analog signal to any acquisition system

how does it work?

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designed for maximum productivity • full data display as graphs, tables, trends

• beat to beat calculation on fast beating tissues

(papillary/atrial muscles)

• detailed calculation on slow contracting tissue (uterus, ileum)

• on-the-fly comment and mark addition

• preprogrammed action triggered by function key or timers

• automated control of stimulators, valves, motors

iox acquisition software

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powerful post-processing

• data extraction• group averaging• ED50• ...

datanalyst software

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electrodes and stimulation• electrodes and stimulators are available from emka TECHNOLOGIES

• third-party stimulators can also be used (iox control is not possible)

how does it work?

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simple to set up and run• completely automated• easy mounting and removal for cleaning• corrosion-resistant • external connections and peripheral devices reduced to a minimum

why use it?

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smart features

open system: analog outputs

electric heating system for baths

• faster response when compared to air heated systems to maintain

temperature control

• more accessible baths when compared with air heated system

why use it?

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smart features

modular solution design

• customization (i.e. bath sizes, tissue-holder, additional measurements such

as pH, etc.)

• up to 16 simultaneous baths with software control

why use it?

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smart features

seamless hardware/software integration• all bath operations are accessible from within the acquisition software

• filling/emptying and/or tissue tension operations are all set in the acquisition

protocol

(no need of a separate tissue bath control application)

• quality control: tissue tension, and temperature data recorded

why use it?

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smart features

fast fill, and empty of baths

pumps for liquid control

overflow-based bath renewal

tissue is never exposed to air: no risk of drying!

easy calibration

why use it?

@emkaTECH

www.facebook.com/emkatechnologies

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