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Copyright © 2009 Pearson Education, Inc.

The Genetic Code and Transcription

Chapter 13 Lecture

Concepts of GeneticsTenth Edition

Copyright © 2009 Pearson Education, Inc. Figure 13.1

Copyright © 2009 Pearson Education, Inc.

13.1 The Genetic Code Uses Ribonucleotide Bases as “Letters”

tripletunambiguousdegeneratestart and stop signalscommalessnonoverlappingalmost universal

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13.2 Early Studies Established the Basic Operational Patterns of the Code

13.2.1 The Triplet Nature of the Code

Copyright © 2009 Pearson Education, Inc. Figure 13.2

Copyright © 2009 Pearson Education, Inc. Figure 13.2a

Copyright © 2009 Pearson Education, Inc. Figure 13.2b

Copyright © 2009 Pearson Education, Inc.

13.2 Early Studies Established the Basic Operational Patterns of the Code

13.2.2 The Nonoverlapping Nature of the Code

13.2.3 The Commaless and Degenerate Nature of the Code

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13.3 Studies by Nirenberg, Matthaei, and Others Led to Deciphering of the Code

13.3.1 Synthesizing Polypeptides in a Cell-Free

System

Copyright © 2009 Pearson Education, Inc. Figure 13.3

Copyright © 2009 Pearson Education, Inc.

13.3 Studies by Nirenberg, Matthaei, and Others Led to Deciphering of the Code

13.3.2 Homopolymer Codes

13.3.3 Mixed Copolymers

Copyright © 2009 Pearson Education, Inc. Table 13.1

Copyright © 2009 Pearson Education, Inc. Figure 13.4

Copyright © 2009 Pearson Education, Inc.

13.3 Studies by Nirenberg, Matthaei, and Others Led to Deciphering of the Code

13.3.4 The Triplet Binding Assay

Copyright © 2009 Pearson Education, Inc.Figure 14-5 Copyright © 2006 Pearson Prentice Hall, Inc.

Figure 13.5

Copyright © 2009 Pearson Education, Inc. Table 13.2

Copyright © 2009 Pearson Education, Inc.

13.3 Studies by Nirenberg, Matthaei, and Others Led to Deciphering of the Code

13.3.5 Repeating Copolymers

Copyright © 2009 Pearson Education, Inc. Figure 13.6

Copyright © 2009 Pearson Education, Inc. Table 13.3

Copyright © 2009 Pearson Education, Inc.Figure 14-7 Copyright © 2006 Pearson Prentice Hall, Inc.

Figure 13.7

Copyright © 2009 Pearson Education, Inc.

13.4 The Coding Dictionary Reveals Several Interesting Patterns among the 64 Codons

13.4.1 Degeneracy and the Wobble Hypothesis

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Copyright © 2009 Pearson Education, Inc.

13.4 The Coding Dictionary Reveals Several Interesting Patterns among the 64 Codons

13.4.2 The Ordered Nature of the Code

13.4.3 Initiation, Termination, and Suppression

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13.6 The Genetic Code Is Nearly Universal

Copyright © 2009 Pearson Education, Inc. Table 13.5

Copyright © 2009 Pearson Education, Inc. Figure 13.8

Copyright © 2009 Pearson Education, Inc. Figure 13.8a

Copyright © 2009 Pearson Education, Inc. Figure 13.8b

Copyright © 2009 Pearson Education, Inc.

13.8 Transcription Synthesizes RNA on a DNA Template

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13.9 Studies with Bacteria and Phages Provided Evidence for the Existence of mRNA

Copyright © 2009 Pearson Education, Inc. Table 13.6

Copyright © 2009 Pearson Education, Inc.

13.10 RNA Polymerase Directs RNA Synthesis

13.10.1 Promoters, Template Binding, and the

Subunit

13.10.2 Initiation, Elongation, and Termination of RNA Synthesis

Copyright © 2009 Pearson Education, Inc. Figure 13.9

Copyright © 2009 Pearson Education, Inc. Figure 13.9a

Copyright © 2009 Pearson Education, Inc. Figure 13.9b

Copyright © 2009 Pearson Education, Inc. Figure 13.9c

Copyright © 2009 Pearson Education, Inc.

13.11 Transcription in Eukaryotes Differs from Prokaryotic Transcription in Several Ways

13.11.1 Initiation of Transcription in Eukaryotes

13.11.2 Recent Discoveries Concerning RNA Polymerase Function

13.11.3 Heterogeneous Nuclear RNA and Its Processing: Caps and Tails

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Copyright © 2009 Pearson Education, Inc. Table 13.7

Copyright © 2009 Pearson Education, Inc.

13.12 The Coding Regions of Eukaryotic Genes Are Interrupted by Intervening Sequences

Copyright © 2009 Pearson Education, Inc. Figure 13.11

Copyright © 2009 Pearson Education, Inc. Figure 13.12

Copyright © 2009 Pearson Education, Inc. Table 13.8

Copyright © 2009 Pearson Education, Inc.

13.11 RNA Editing May Modify the Final

Transcript

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13.14 Transcription Has Been Visualized by Electron Microscopy

Copyright © 2009 Pearson Education, Inc. Figure 13.15

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