clinical presentation and diagnosis of tuberculosis

Clinical Presentation and Diagnosis of TuberculosisSlides from the web site http://www.tbrieder.org

Compiled by:

Hans L Rieder

Background of stained smears

Acid-alcoholdestainedsmear

Sulfuric aciddestainedsmear

Picture courtesy: Kim SJ. Unpublished Lecture Notes, Hanoi, August 31, 2001

a

b

c

Sturisoma festivum

Picture courtesy: Van Deun AJune 13, 2004

The Sites of Vertebral Tuberculosis

Paradiscal

Central

Anterior

Posteriorappendicial

PosteriorFacet joints

Tuli SM. Clin Orthopaed 2002;398:11-9

Posteriorappendicial

Affected Vertebrae in Spinal Tuberculosis

Cervical

Thoracic

Lumbar

Sacral

Chen WJ, et al. Acta Orthop Scand 1995;66:137-42

From: http://www.chirogeek.com/000_Disc_Anatomy.htm

Anatomy and the Nutrition of the Intervertebral Disc

Anterior Posterior

Pathogenesis of Tuberculosis of the Spine

De Vuyst D. Eur Radiol 2003;13:1809-19

Osseous Tuberculous Foci in the Hip

Acetabular

Epiphyseal

Trochanteric

Metaphyseal

Tuli SM. Clin Orthopaed 2002;398:11-9

At diagnosis After 2 months

Mycobacterium tuberculosis Bacteremia inFebrile Patients in Dar es Salaam, Tanzania

Per

cen

t

0

5

10

15

20

25

HIV neg

HIV pos

Archibald LK, et al. Clin Infect Dis 1998;26:290-6

died

survived

Donald PR, et al. N Engl J Med 2004;351:1719-20

Change in cerebrospinal fluid findings in a child with tuberculous meningitis

Date White cell count

Polynuclear (%)

Mononuclear (%)

Protein Sugar

26 July 9 - - ++ 0

27 July 213 71 29 +++ 0

30 July 509 16 84 +++ 0

Tuberculous Chorioretinitis

Lanzafame M, et al. Lancet 2001;357:1390

Response to chemotherapy of tuberculosis verrucosa cutis

At diagnosis After 1 month After 3 months