chemistry 20-dna-replication-and-repair
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Chapter 20
DNA Replication and Repair
Replication is bidirectional
DNA Replication is Semidiscontinuous
Okazaki Fragments
DNA Polymerase III is a Multisubunit Enzyme
DNA Polymerase III Subunit Organization
DNA Replication
is a Processive Process.
Stages of DNA Replication
• Initiation•Elongation •Termination
PCNA analogous to E. coli b-subunit of E. coli DNA
polymerase
Repair of UV Induced Thymine
Dimers
General excision-repair
pathway
Repair of damage resulting from the
deamination of cytosine
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