anti ageing treatment with stem cells

SKIN, FACE REJUVENATION AND

HAIR RESTORATION

Website : www.stemgenn.com | Email : Contact@stemgenn.com | Phone : +91 9811011690

Website : www.stemgenn.com | Email : Contact@stemgenn.com | Phone : +91 9811011690

Hair loss

Development of fine lines and wrinkles, itchy or dry skin

Sagging skin from loss of underlying fat or bone mass

Development of spider and varicose veins and

Thinning or transparent skin

DAUNTING DREAMS OF OLD AGE

Website : www.stemgenn.com | Email : Contact@stemgenn.com | Phone : +91 9811011690

ADSCs AND PRP

PRP (Platelet Rich Plasma) and Adipose Derived Stem Cells (ADSCs) are revolutionary techniques which are

allowing rejuvenation of the skin, face and hair restoration using the patient’s own (autologous) cells,

with long lasting effects.

Website : www.stemgenn.com | Email : Contact@stemgenn.com | Phone : +91 9811011690

VAMPIRE FACE LIFT

PRP is a concentrated blood sample that contains high levels of platelets, a critical component of the wound healing process.

Platelets contain growth factors that are responsible for stimulating tissue generation and repair. Growth factors derived from platelets are responsible for soft tissue repair, hair growth, development of new blood vessels, and stimulation of the wound healing process.

Website : www.stemgenn.com | Email : Contact@stemgenn.com | Phone : +91 9811011690

WHY PLATELETS

Vascular endothelial growth factor (VEGF) Growth and new generation of vascular endothelial cells. Significant

mediator of hair follicle growth and cycling, providing the first direct evidence that improved follicle vascularisation promotes hair growth,

as well as increasing follicle and hair size.

Platelet-derived growth factor (PDGF)Cell growth, new generation and repair of Blood vessels, collagen production. PDGF is a required element in cellular division for fibroblasts, a type of connective tissue

cell that is especially prevalent in wound healing.

Transforming Growth Factors (TGF a and b)Growth and neogenesis of epithelial cells and vascular endothelial cells, promotion

of wound healing.Favours the synthesis of collagen.

Epidermal growth factor (EGF)Stimulates cell growth, proliferation, and

differentiation of epidermis cell. It effect on the proliferation of basal

keratinocytes and of cells that comprise the outer root sheath of hair.

Insulin-like growth factor 1 (IGF-1)Regulates the expression of a powerful messenger cellular level, which is anti-

apoptotic and capable of preventing the cell death.

Fibroblast growth factor (FGF)

Tissue repair, cell growth, collagen production, hyaluronic acid production

PLATELETS

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PRP PROCEDURE

Speed and duration of centrifugation is very important to ensure the platelets are not damaged

Patient autologous (own)cell

Centrifuged the blood

Before PRP

After PRP

Before PRP

After PRP

Website : www.stemgenn.com | Email : Contact@stemgenn.com | Phone : +91 9811011690

RESULTS OF PRP

Also Includes

Stimulating hair growth

Decreasing facial rhytids

Enhancing the taking rate of fat transplant

stimulate collagen production in the subcutaneous tissues

when used as a filler (alone or combined with collagen or

hyaluronic acid

Decreasing hematoma/seroma post rhytidectomy, Improving the appearance of stretch marks and scars (alone or in combination with laser).

Website : www.stemgenn.com | Email : Contact@stemgenn.com | Phone : +91 9811011690

ADVANTAGES OF PRPPromotes local tissue growth and repair.

Patient’s safety – patient’s own blood, therefore no disease transmission, non toxic and no rejection.

Conveniently PRP prepared at doctor’s office.

Faster healing- platelets accelerate tissue synthesis.

Cost effectiveness- no need for external substances.

Simple and easy to use.

Website : www.stemgenn.com | Email : Contact@stemgenn.com | Phone : +91 9811011690

ADIPOSE DERIVED STEM CELLS

Human adipose tissues that contain Adipose-derived stem cells (ADSCs) are one of the latest scientific breakthroughs in the field of aesthetic surgery.

ADSCs are easily isolated from fat tissue harvest by liposuction, and they can differentiate into several types of lineages in culture.

ADSCs are likely to be pluripotent Mesenchymal Stem cells (MSCs), which share similar characteristics with Bone marrow Stem cells (BMSCs).

ADSCs have paracrine effects on their surrounding environment through the secretion of many growth factors, such as vascular endothelial growth factor (VEGF), hepatocyte growth factor (HGF), basic fibroblast growth factor (bFGF), platelet-derived growth factor (PDGF), keratinocyte growth factor (KGF), transforming growth factor (TGF)-E1, insulin-like growth factor-binding protein (IGF-BP) precursors, fibronectin, and superoxide dismutase (SOD).

These proteins secreted by ADSCs exert diverse hair growth, skin-rejuvenating effects, such as the stimulation of collagen synthesis and fibroblast migration during wound healing.

Website : www.stemgenn.com | Email : Contact@stemgenn.com | Phone : +91 9811011690

ADSCs PROCEDURE Adipose tissue aspiration

from patient

Isolation of ADSCs

Concentration of ADSCs

Before ADSCs After ADSCs

Before ADSCs After ADSCs

Injection of ADSCs in patient

Website : www.stemgenn.com | Email : Contact@stemgenn.com | Phone : +91 9811011690

RESULTS OF ADSCsHair growth

Website : www.stemgenn.com | Email : Contact@stemgenn.com | Phone : +91 9811011690

ADVANTAGES OF ADSCs

Long-term stability.

Lyophilized ADSC-CM avoids most of the safety issues.

Use of ADSC may also enhance the scalability of production, low-cost therapeutics.

Website : www.stemgenn.com | Email : Contact@stemgenn.com | Phone : +91 9811011690

FACTS ABOUT ADSCs & PRP

“Stem cells have a mystique—they’re chameleon-like cells that are thought to be able to make skin look fresh and young,” says Erin Gilbert, a leading dermatologist from NewYork

Notable celebrities such as Reese Witherspoon, Madonna, Jacqueline Bisset, J.lo and even Marc Anthony reportedly use stem cell treatments as part of their skin rejuvenation.

StemGenn Therapeutics is a leading Cell therapy & Regenerative medicine

services company that supports the development and commercialization of

cellular therapies and stem cell research

• As Stem cell have inherent properties to self renew and differentiation into other cell types. They are multi potent and found within our body.• No side effects: As it's found in patient's own tissues or blood chances of rejection and infection is negligible.• World class clinicians and experts from Regenerative Medicine.• Cost Effectiveness: Autologous stem cell transplant is very much affordable.• Non- Surgical Procedure & convenient.• Proven Results.

Website : www.stemgenn.com | Email : Contact@stemgenn.com | Phone : +91 9811011690

Website : www.stemgenn.com | Email : Contact@stemgenn.com | Phone : +91 9811011690

Richa Jha Managing Director, Founder

Prabhu Mishra President, CEO, Co-Founder

– ‘Secretary General- Stem Cell Society, India.’

Shreyashi Gangopadhyay Director, Business Development & Project

Management

Website : www.stemgenn.com | Email : Contact@stemgenn.com | Phone : +91 9811011690

Dr. Sharda Jain MD, MANMS,

FICOG, FIMSA, DHM, QM & AHO, Secretary General – Delhi Gynae

Forum

Dr Harinder Singh Bedi MCh, Director Cardio Vascular,

CMC Ludhiana

Dr Satish ToteyPhD, More than 35 yr work

experience in Stem Cell Research

Dr. Roopam JainMBBS,DCP, MD, DNB

(Immunohematology & Transfusion Med) ,Ass. Proff.RD Gardi Medical college

Dr. Rahul Bhargava MBBS, MD, DM, Post DM Fellowship, Bone Marrow Transplant Specialist

Website : www.stemgenn.com | Email : Contact@stemgenn.com | Phone : +91 9811011690

BLOOD RELATED DISEASES: Thalssemia, Sickle Cell Anemia, Aplastic Anemia. 1

2 AUTOIMMUNE DISEASES: Type 1 Diabetes, Rheumatoid Arthritis, Chronic Disease, Multiple Sclerosis, Myasthenia Gravis, Ankylosing Spondylitis, COPD, ILD.

3 NEUROLOGICAL DISORDERS: Cerebral Palsy, Stroke, Spinal Cord Injury, Cerebral Atrophy, Muscular Dystrophy, Autism, Multiple Sclerosis, ALS.

4 ORTHOPAEDIC DISEASE: Avascular Necrosis, Osteoarthritis, Non Union Fracture, Chondromalacia Patallae, Sport Injury.

5 LIFESTYLE DISEASES: Diabetes, Liver Cirrhosis, Chronic Kidney, disease, Erectile Dysfunction, Anti - Aging.

6 STEM CELL CONSULTING AND TRAINING PROGRAM: Regenerative Medicine Lab Setup, Cord Blood Bank Set Up, Regulatory and Scientific Support.

Website : www.stemgenn.com | Email : Contact@stemgenn.com | Phone : +91 9811011690

StemGenn Therapeutics is key segment………….

Website : www.stemgenn.com | Email : Contact@stemgenn.com | Phone : +91 9811011690

Mita Stem cell in cosmetics is future.

Mona

Website : www.stemgenn.com | Email : Contact@stemgenn.com | Phone : +91 9811011690

Ashutosh

Stem cell treatment is really great, after treatment my skin is glowing & fine lines is gone. Thanks to StemGenn stem cell treatment is wonderful & worth of money .

StemGenn training program is excellent.

Deepika (Dietician) My Skin is also glowing. Its really magic; Pigmentation is not all visible.

Dr. Shaloo Gupta

Website : www.stemgenn.com | Email : Contact@stemgenn.com | Phone : +91 9811011690

Dr. Ruby Srivastava

StemGenn anti ageing treatment provides prolonged effect.Skin is glowing and feeling wonderful. When do we get our supply of magic glow.

StemGenn anti ageing treatment is amazing treatment. Glow came and fine lines minimised.

Website : www.stemgenn.com | Email : Contact@stemgenn.com | Phone : +91 9811011690

Website : www.stemgenn.com | Email : Contact@stemgenn.com | Phone : +91 9811011690

REFERENCEShttp://barefacedtruth.com/how-skin-ages/

European Journal of Dentistry

http://www.harvesttech.com/harvest-prp

http://www.dermnetnz.org/procedures/platelet-rich-plasma.html

Minimally Invasive Procedures for Facial Rejuvenation; Dr. C Giuseppe and Dr. R. Antonio

The American Journal of Cosmetic Surgery Vol. 29, No. 4, 2012

https://en.wikipedia.org/wiki/Epidermal_growth_factor

https://en.wikipedia.org/wiki/Platelet-derived_growth_factor, June 2013; prime-journal.com; Platelet-Rich Plasma: A Therapy For Hair Growth