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Algal Plant Proteins (MicroAlgae)
A Disruptive Opportunity
Market Trends, Technologies, Key Success Factors
23 May 2017
In our previous episode…
May 2015, Matt Carr – Algae Biomass –
…reported key motivating factors and state of
commercialization for alternative microalgae
farming, yield & sustainability.
At that time, price for barrel oil still expected to increase, with
huge investment in algae-based biofuels.
Microalgae was primarily directed to added-value dietary
supplements & cosmeceuticals.
Investment in algal protein sources was still limited.
2017+ … Algal Proteins have indeed become a strategic factor for global
food & beverage industries, aqua-farming & animal nutrition.
2015 Milestones, SepEU Sustainable, Safe and Nutritious Food, New Nutrient Sources
Lux Research
Global protein consumption is estimated to reach 944 MMt by 2054.
Animal protein dominance will decrease over next decades.
Consumption of alternative protein sources to grow by 9% annually.
By 2054, up to 33% of the total protein consumption, i.e. 311 MMt.
o Algae 2024 … ~2% of alternative protein market
o Algae 2054 … ~18% of alternative protein market, i.e. 56 MMt. *
Sustainable, Safe & Nutritious Food
2015 Milestones, DecRabobank Industry Note, Algae: A Brave New Industry
Researchers still focused on traditional sources: Spirulina, Chlorella, Porphyridium,
Nannochloropsis, Astaxanthin, Dunaliella, Fucoxanthin.
72,000 other algae species, offer different properties, farming methods,
applications, volumes and price-points … and not IP protected!
Rabobank – KSF for Microalgae Proteins
o Farming of algae will need to take place on a larger scale.
o Market forces are essential to commercializing technologies.
o Supporting a smarter food system requires managing risks (Technology,
Market, Business, Regulatory, Reputational).
2015 Milestones, Dec Rabobank Industry Note, Algae: A Brave New Industry
In order to match the quality of animal & traditional plant protein sources, the way
forward is to blend different types of plant proteins to optimize & harmonize
nutritive values & obtain advantageous amino acid content.
Sustainable, Safe & Nutritious Food
2nd + 3rd generation plant
(pulse) + Algae (+ Insects)
proteins change metrics
of global agri biodiversity.
Microalgae Sustainability
Matt CarrMay, 2015
Algal Protein Key Success Factors
Microalgae Protein
Protein value proposition drives all other considerations…
Algal Protein Screening & Selection Process Key Success Factors
Microalgae Protein
Location
Autotrophic or Heterotrophic species, and where to source optimal strains:
o Reactors, Ponds, Raceways – outdoor open systems
o Fermentation – indoor fermentation tanks
Microalgal Species selection
Water source
Medium use
Continuous or batch culture
Downstream processing & final product (Human consumption or feed?)
Allergenicity, ANF (anti-nutritional factors)
Process strategy to achieve high protein yields
Alternative Microalgae Protein Growing Systems
Algal Protein Characteristics & FunctionalitiesKey Success Factors
Microalgae Protein
Amino Acid Profile
Digestibility (PDCAAS, DIAAS)
Solubility (pH)
Emulsification
Heat Stability
Color
Flavor & Taste
Viscosity
Gelling
Functionalities giving synergistic properties with other alternative plant & algae proteins.
Algal Oil Key Success Factors
Microalgae Protein
Triglycerides
Fatty Acid Profile
Micronutrients
o Vitamins & minerals
o Antioxidants
o Phytochemicals
o Carotenoids
Fibers
Added value fractions to strengthen algal protein business model.
Algal Protein Key Success Factors
Microalgae Protein
US$ 6-8 / Kg for ~70% algal protein concentrate
o Benchmark: alternative plant proteins (soy, pea, whey)
oNot niche product
Large volumes
Versatility for F&B applications
o Food• Meat & non-Meat• Food & beverage• Bakery & patisserie• High nutritional value foods (sports, infant, medical foods)
o Animal & aqua
Develop additional algal fractions
Facilities close-to-market / Contingency Plan
Alternative Plant Protein Value ChainSoy Case Study
Alternative Protein Value ChainMicroalgae Case Study
Known Protein Producing Microalgae Strains
72,000 other sources ?
Screening & Selecting, Challenges for Microalgae ProteinsTechnology readiness levels (TRL)
Growing & processing
Cellulosic cell wall poses serious problem
in digesting/utilizing algal biomass.
Hence, effective treatments necessary
to disrupt cell wall.
Drying method can drastically affect
nutritional quality of the algal protein.
Downstream
Nutritional benefits & Functionalities
Added value fractions
Cost of Goods (COGS)
Ability to compete with other alternative
plant proteins in food/feed products.
The European Perspective
European Institute of Innovation and Technology
EIT Food, a €1.2 Billion Multi-Year Initiative
EIT Food, a €1.2 Billion Multi-Year Initiative
Senior Vice PresidentPepsiCo
https://eit.europa.eu/newsroom/eit-selects-winning-innovation-partnership-food
https://eit.europa.eu/eit-community/eit-food
EIT Food Innovation ProgramsFramework for microalgae protein project
Title of Proposed Idea:
Develop innovative algal plant-based protein sources with important functional
properties needed for a wide variety of food and beverage applications.
Objective:
To develop sustainable algal plant-based protein sources for a wide range of
applications, including meat & non-meat alternatives, food & beverage, bakery &
patisserie products, and food products with a high nutritional value (including
sports nutrition, infant formula and medical foods for elderly). The project aims
to develop cost-effect, highly functional and good tasting specialty proteins
with important essential amino acid profiles.
EIT Food ‘IDEA’ Assumptions & KSF for Algae-based Proteins
Develop new micro-algae sources, for protein & other nutritional properties,
selecting top 3-4 for further evaluation (COGS for growing and down-processing).
Implement established technologies:
o Growing, harvesting & down-processing of high protein algal sources;
o Extraction and separation to utilize all fractions (protein, lipid, polysaccharide,
fiber...) for food and nutritional applications/products.
Analyze all functional properties, for most suitable applications; to achieve early
business wins & long term sustainable business opportunities.
Nutritional by-products & value streams of micro-algae fractions to be evaluated.
EIT Food ‘IDEA’ Assumptions & KSF for Algae-based Proteins
EIT Food, a €1.2 Billion Multi-Year Initiative
Plant Protein Industry Standards (Guidelines)
Thank you to: David Plank, Factors impacting Protein Quality & a New Way for Measuring, May ‘16
Will CRISPR Technologies be Used?
CRISPR/Cas9 and Targeted Genome Editing: A New Era
in Molecular Biology
A CRISPR/Cas9 system adapted for gene editing in
marine algae
Genome editing of model oleaginous microalgae
Nannochloropsis spp. by CRISPR/Cas9
Food & Microalgae ProteinsIngredients Insight: Proteins – Dec ‘16
Protein continues to be sought out by consumers and is considered a part of
a healthy diet.
Consumers are becoming more interested in plant-based protein options.
Consequently, there has been an increase of vegetarian and vegan claims on
high protein food and drink launches.
Other market drivers (relevant for microalgae): Allergen free, Gluten free,
Lactose free.
Sustainable & environment friendly cultivation, processing and supply are
key success factors.
While pea, chickpea, lupine, seeds & nuts, and insect proteins are all
mentioned in new product launches, a microalgae Search shows only 120
products product launches 2012-2017. However…
Many of these products are from seaweed and not microalgae.
Only 24 out of 120 are actually found in food & beverage products; the remainder
dietary supplements.
~16 out of 24 are either infant formula or breastfeeding products, i.e. for DHA-EPA
health benefits.
A separate search microalgae protein shows
2 food products, both dry blend powder
mixes w/ Spirulina.
Conclusions
Food & Beverage applications for microalgae
proteins is still an untapped market category.
Food & Microalgae ProteinsIngredients Insight: Proteins – Dec ‘16
??
??
?
?
Microalgae Protein Versatility for Multiple Categories
…A reminder that in targeting multiple food & beverage categories, there is an
important role for food technology, bench application development, and
downstream processing of microalgae proteins.
(circa 1997)
Aquaculture & Microalgae
In contrast with human
consumption, use of
microalgae by growing
aquaculture industry is already
thriving.
Aquaculture The production &
husbandry of aquatic animals
& plants in controlled
environments.
UN-FAO The State of World Fisheries and Aquaculture 2016
The Food & Agricultural Organization (FAO) acknowledge that global fishery output
must be increased by ≥50% to offset projected shortfalls in dietary protein by 2030.
The use of microalgae in fish hatcheries is for both production of live prey and
greening the larvae rearing medium.
~30-40 million tons must be produced in
order to achieve 50% increase in global
aquaculture production.
Realistically, this goal can only be met by
further development of new intensive
aquaculture systems and intensification of
existing facilities.
Intensive Culture Systems represent >90%
of projected growth within next decade.
Cultivated microalgae are integral part of
hatchery production and commercially
important aquaculture species.
Aquaculture & Microalgae
Microalgae provide important direct or indirect feed
source for early developmental stages of species.
Hatcheries have traditionally cultivated microalgae
in-house or collected microalgae from natural
environments.
Commercial concentrates & dried products were
introduced into the industry during last decade.
The success of introducing external microalgae
source to marine hatcheries is based on several
critical parameters:
Aquaculture & Microalgae
o Product performance (survival, growth ratios, anatomical disorders)o Repeatability and consistency of producto Absence of infectious diseaseo Price
The microalgae requirement for the rearing and enrichment of rotifers is 1000 kg
of microalgae paste for production of 10 M juveniles (2g).
We are involved in a microalgae aqua project in Turkey-Greece, where the demand
for Nannochloropsis alone is projected to be 79 MT per annum, for one species
only! There are several species now in the pipeline.
Per 2015 Rabobank Report - Farming of algae will need to take place on a larger
scale; Market forces are essential to commercializing technologies; Supporting a
smarter food system requires managing risks.
Therefore, having a combined Food/Feed Microalgae Strategy is essential to any
Algal Protein Business Plan.
Food + Feed (Aqua) & Microalgae, Strategic Plan
EIT Food ‘FINAL PROPOSAL’ Deliverables for Algae-based Proteins … Oct ‘17 – Dec ‘18
Title Description
Identification of heterotrophic microalgae strains
“Early Bird” '17 efforts, results of species screening & selection. IP-FTO report.
Testing identified strains for fast growing & high yields
Test results should be completed by end-May '18. Regulatory pathways (ANF, allergenicity).
Optimization of the process in the selected media Processing selected media, small scale bioreactors, mid-Oct '18.
Establish new capabilities for functional properties protein concentrates
By 3 universities and commercial companies - once supplied with microalgae biomass samples, Jul-Nov ’18.
Implementation new processes, pre-scaling design & first cost-benefit analysis
Cultivating & concentrating new protein sources, pre-industrial scale … simulate ingredients to be commercialized, Aug-Oct ’18.
Consumer product acceptance studies by market segment
First new food & beverage products, specifications & samples for evaluation, Nov-Dec ’18.
Thank you!
Gary Brenner
Brenner pharma/food Business Development Ltd.
Kibbutz Hatzor, Hatzor-Ashdod 6097000 Israel
garybrenner@pharmafood-bd.com
www.pharmafood-bd.com
+972 52-7215299
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