2012_12 management of mdr-tb in children a field guide_0
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Management of Multidrug-Resistant Tuberculosis in Children: A Field Guide
Management of Multidrug-Resistant Tuberculosis in Children: A Field Guide
Acknowledgements
Table of Contents
Introduction 2
Section 1: Diagnosis 45
812
Section 2: Regimen Design 141417
Section 3: Monitoring 232324262830
Section 4: Infection Control 333334
Selected References 36
Appendices 38424446
2 Introduction
Introduction
et al.
Mangement of Drug-Resistant Tuberculosis in Children 3
4 Diagnosis of DR-TB in Children
Recognition and Initial Management of a Child with Suspected
MDR-TB
Section 1: Diagnosis of MDR-TB in Children
Mangement of Drug-Resistant Tuberculosis in Children 5
Algorithm for Suspected MDR-TB in a Child
6 Diagnosis of DR-TB in Children
Case Examples: Suspected MDR-TB in a Child
Mangement of Drug-Resistant Tuberculosis in Children 7
8 Diagnosis of DR-TB in Children
Diagnostic Specimen Management
Mangement of Drug-Resistant Tuberculosis in Children 9
Mycobacterium tuberculosisM. tuberculosis
10 Diagnosis of DR-TB in Children
minim
um
Types of Specimens
Mangement of Drug-Resistant Tuberculosis in Children 11
minim
um
First
12 Diagnosis of DR-TB in Children
Management Algorithm for Child Contacts of MDR-TB Cases
Mangement of Drug-Resistant Tuberculosis in Children 13
Case Example: Contact
th
14 Regimen Design
Principles of Regimen Design: Pediatric Considerations
et al.
Section 2: Regimen Design
Mangement of Drug-Resistant Tuberculosis in Children 15
Case Examples: Regimen Design
16 Regimen Design
M. tuberculosis
Mangement of Drug-Resistant Tuberculosis in Children 17
Dosing of Second-Line Antituberculous Agents For Pediatrics
18 Regimen Design
Weight-Based Dosing in Children
Mangement of Drug-Resistant Tuberculosis in Children 19
20 Regimen Design
Mangement of Drug-Resistant Tuberculosis in Children 21
22 Regimen Design
hours
Mangement of Drug-Resistant Tuberculosis in Children 23
Section 3: Monitoring
1 3 4 5 6 9 15 18
A proposed monitoring schedule
24 Monitoring
Mangement of Drug-Resistant Tuberculosis in Children 25
26 Monitoring
Co-Morbid Conditions
Mangement of Drug-Resistant Tuberculosis in Children 27
and or
Algorithm for Management of Children on Treatment for MDR-
TB and HIV
28 Monitoring
Adherence
Mangement of Drug-Resistant Tuberculosis in Children 29
Case Examples: Adherence
30 Monitoring
Nutritional Monitoring for Children with MDR-TB
Mangement of Drug-Resistant Tuberculosis in Children 31
32 Monitoring
TB
Mangement of Drug-Resistant Tuberculosis in Children 33
Facility-Based Infection Control
Section 4: Infection Control
34 Infection Control
Case Example: Infection control
Community-Based Infection Control
Mangement of Drug-Resistant Tuberculosis in Children 35
Case Example: Infection Control
36 References
Selected References
Mangement of Drug-Resistant Tuberculosis in Children 37
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38 Appendices
Appendix A: Sample Intake Form
Mangement of Drug-Resistant Tuberculosis in Children 39
40 Appendices
Mangement of Drug-Resistant Tuberculosis in Children 41
Y Y Y Y P
Y Y Y Y P
Y Y Y Y P
Y Y Y Y P
o or
C
42 Appendices
Appendix B: Medications Used to Treat
MDR-TB
Mangement of Drug-Resistant Tuberculosis in Children 43
44 Appendices
Appendix C: Contact Management Form for
Children Exposed to MDR-TB
Mangement of Drug-Resistant Tuberculosis in Children 45
46 Appendices
Appendix D: Protocols for Specimen
Collection
Gastric Aspiration
Mangement of Drug-Resistant Tuberculosis in Children 47
Sputum Induction
General:
48 Appendices
Management of materials
Management of the environment
Mangement of Drug-Resistant Tuberculosis in Children 49
50 Appendices
Mangement of Drug-Resistant Tuberculosis in Children 51
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