By-Dr KRAGHU RAMUDU

2nd year PG ScholarDepartment of Dravyaguna

SVAyurvedic collegeTirupatiAndhra pradesh

Review of Scientific studies on Amavatahara drugs

Dr M Paramkussh RauMD(DG)PhD

PGProfessoramp HODDepartment of Dravyaguna

SVAyurvedic collegeTirupatiAndhra pradesh

Introduction

Amavata is the most crippling of the joint diseases It occurs throughout the world in all climates

First explained in Madhava Nidana by Madhavakara

Ama and vitiated Vata play the dominant role so it is called as Amavata

The incidence of Amavata (Rheumatoid Arthritis) is

reported to be 1-2 of general population with a

female to male ratio of 31

Nidana amp Samprapthi

Viruddahara means unwholesome foods or combination of foods which effects adverselyPoor digestion power defective metabolismSedentary life style and also too much exercise

So affected defective metabolism with the influence of nervous system also affects the normal functioning and the products of this reaches Dhamanis(blood vessels) and circulates all over the body and produces symptoms

Samanya lakshanas

BodyachePoor appetite feeling thirsty lethargicHeavyness in the bodyFever feelingNon inflammatory and no suppurative nature

Severe AMAVATA features Very difficult to tolerate when becomes severe Can

also be considered as difficult to treat when aggravates

Severe pain in hand foot head ankle neck low back knee and hip joints

Pain and swelling is seen in different parts of body

Pain will be severe as if bit by scorpion (burning sensation and pain as if hit by stick)

with the use of NSAIDrsquos (Non Steroidal

Anti Inflammatory Drugs) glucocorticoids DMARDrsquos

(Disease Modifying Anti Rheumatic Drugs) treatment

remains unsatisfactory through modern system of

medicine Patients are continuously looking with a hope

towards Ayurveda to overcome this challenge

So the Ayurvedic medicinal herbs are moving to

mainstream

Pippali (Piper longum Linn)

Pippali is one of the Rasayana drugs described in Ayurveda It has Agnidipana and Amapachana actions and is helpful in the alleviation of Ama from the body which is the main pathological factor in Amavata ie rheumatoid arthritis

Pippali alleviates Ama the factor responsible for Balabhrmsha or development of autoimmune disorders in the body resulting in the correction in immune system activities Pippali has rasayana and immunomodulator actions Thus because of all these actions together it plays an important role in the Samprapti-vighatana of the Amavata ie rheumatoid arthritis

Ref Clinical evaluation of Vardhamana Pippali Rasayana in the management of Amavata (Rheumatoid

Arthritis) Anamika Soni1 Kalapi Patel2 and S N Gupta3

Introduction

Amavata is the most crippling of the joint diseases It occurs throughout the world in all climates

First explained in Madhava Nidana by Madhavakara

Ama and vitiated Vata play the dominant role so it is called as Amavata

The incidence of Amavata (Rheumatoid Arthritis) is

reported to be 1-2 of general population with a

female to male ratio of 31

Nidana amp Samprapthi

Viruddahara means unwholesome foods or combination of foods which effects adverselyPoor digestion power defective metabolismSedentary life style and also too much exercise

So affected defective metabolism with the influence of nervous system also affects the normal functioning and the products of this reaches Dhamanis(blood vessels) and circulates all over the body and produces symptoms

Samanya lakshanas

BodyachePoor appetite feeling thirsty lethargicHeavyness in the bodyFever feelingNon inflammatory and no suppurative nature

Severe AMAVATA features Very difficult to tolerate when becomes severe Can

also be considered as difficult to treat when aggravates

Severe pain in hand foot head ankle neck low back knee and hip joints

Pain and swelling is seen in different parts of body

Pain will be severe as if bit by scorpion (burning sensation and pain as if hit by stick)

with the use of NSAIDrsquos (Non Steroidal

Anti Inflammatory Drugs) glucocorticoids DMARDrsquos

(Disease Modifying Anti Rheumatic Drugs) treatment

remains unsatisfactory through modern system of

medicine Patients are continuously looking with a hope

towards Ayurveda to overcome this challenge

So the Ayurvedic medicinal herbs are moving to

mainstream

Pippali (Piper longum Linn)

Pippali is one of the Rasayana drugs described in Ayurveda It has Agnidipana and Amapachana actions and is helpful in the alleviation of Ama from the body which is the main pathological factor in Amavata ie rheumatoid arthritis

Pippali alleviates Ama the factor responsible for Balabhrmsha or development of autoimmune disorders in the body resulting in the correction in immune system activities Pippali has rasayana and immunomodulator actions Thus because of all these actions together it plays an important role in the Samprapti-vighatana of the Amavata ie rheumatoid arthritis

Ref Clinical evaluation of Vardhamana Pippali Rasayana in the management of Amavata (Rheumatoid

Arthritis) Anamika Soni1 Kalapi Patel2 and S N Gupta3

Nidana amp Samprapthi

Viruddahara means unwholesome foods or combination of foods which effects adverselyPoor digestion power defective metabolismSedentary life style and also too much exercise

So affected defective metabolism with the influence of nervous system also affects the normal functioning and the products of this reaches Dhamanis(blood vessels) and circulates all over the body and produces symptoms

Samanya lakshanas

BodyachePoor appetite feeling thirsty lethargicHeavyness in the bodyFever feelingNon inflammatory and no suppurative nature

Severe AMAVATA features Very difficult to tolerate when becomes severe Can

also be considered as difficult to treat when aggravates

Severe pain in hand foot head ankle neck low back knee and hip joints

Pain and swelling is seen in different parts of body

Pain will be severe as if bit by scorpion (burning sensation and pain as if hit by stick)

with the use of NSAIDrsquos (Non Steroidal

Anti Inflammatory Drugs) glucocorticoids DMARDrsquos

(Disease Modifying Anti Rheumatic Drugs) treatment

remains unsatisfactory through modern system of

medicine Patients are continuously looking with a hope

towards Ayurveda to overcome this challenge

So the Ayurvedic medicinal herbs are moving to

mainstream

Pippali (Piper longum Linn)

Pippali is one of the Rasayana drugs described in Ayurveda It has Agnidipana and Amapachana actions and is helpful in the alleviation of Ama from the body which is the main pathological factor in Amavata ie rheumatoid arthritis

Pippali alleviates Ama the factor responsible for Balabhrmsha or development of autoimmune disorders in the body resulting in the correction in immune system activities Pippali has rasayana and immunomodulator actions Thus because of all these actions together it plays an important role in the Samprapti-vighatana of the Amavata ie rheumatoid arthritis

Ref Clinical evaluation of Vardhamana Pippali Rasayana in the management of Amavata (Rheumatoid

Arthritis) Anamika Soni1 Kalapi Patel2 and S N Gupta3

Samanya lakshanas

BodyachePoor appetite feeling thirsty lethargicHeavyness in the bodyFever feelingNon inflammatory and no suppurative nature

Severe AMAVATA features Very difficult to tolerate when becomes severe Can

also be considered as difficult to treat when aggravates

Severe pain in hand foot head ankle neck low back knee and hip joints

Pain and swelling is seen in different parts of body

Pain will be severe as if bit by scorpion (burning sensation and pain as if hit by stick)

with the use of NSAIDrsquos (Non Steroidal

Anti Inflammatory Drugs) glucocorticoids DMARDrsquos

(Disease Modifying Anti Rheumatic Drugs) treatment

remains unsatisfactory through modern system of

medicine Patients are continuously looking with a hope

towards Ayurveda to overcome this challenge

So the Ayurvedic medicinal herbs are moving to

mainstream

Pippali (Piper longum Linn)

Pippali is one of the Rasayana drugs described in Ayurveda It has Agnidipana and Amapachana actions and is helpful in the alleviation of Ama from the body which is the main pathological factor in Amavata ie rheumatoid arthritis

Pippali alleviates Ama the factor responsible for Balabhrmsha or development of autoimmune disorders in the body resulting in the correction in immune system activities Pippali has rasayana and immunomodulator actions Thus because of all these actions together it plays an important role in the Samprapti-vighatana of the Amavata ie rheumatoid arthritis

Ref Clinical evaluation of Vardhamana Pippali Rasayana in the management of Amavata (Rheumatoid

Arthritis) Anamika Soni1 Kalapi Patel2 and S N Gupta3

Severe AMAVATA features Very difficult to tolerate when becomes severe Can

also be considered as difficult to treat when aggravates

Severe pain in hand foot head ankle neck low back knee and hip joints

Pain and swelling is seen in different parts of body

Pain will be severe as if bit by scorpion (burning sensation and pain as if hit by stick)

with the use of NSAIDrsquos (Non Steroidal

Anti Inflammatory Drugs) glucocorticoids DMARDrsquos

(Disease Modifying Anti Rheumatic Drugs) treatment

remains unsatisfactory through modern system of

medicine Patients are continuously looking with a hope

towards Ayurveda to overcome this challenge

So the Ayurvedic medicinal herbs are moving to

mainstream

Pippali (Piper longum Linn)

Pippali is one of the Rasayana drugs described in Ayurveda It has Agnidipana and Amapachana actions and is helpful in the alleviation of Ama from the body which is the main pathological factor in Amavata ie rheumatoid arthritis

Pippali alleviates Ama the factor responsible for Balabhrmsha or development of autoimmune disorders in the body resulting in the correction in immune system activities Pippali has rasayana and immunomodulator actions Thus because of all these actions together it plays an important role in the Samprapti-vighatana of the Amavata ie rheumatoid arthritis

Ref Clinical evaluation of Vardhamana Pippali Rasayana in the management of Amavata (Rheumatoid

Arthritis) Anamika Soni1 Kalapi Patel2 and S N Gupta3

with the use of NSAIDrsquos (Non Steroidal

Anti Inflammatory Drugs) glucocorticoids DMARDrsquos

(Disease Modifying Anti Rheumatic Drugs) treatment

remains unsatisfactory through modern system of

medicine Patients are continuously looking with a hope

towards Ayurveda to overcome this challenge

So the Ayurvedic medicinal herbs are moving to

mainstream

Pippali (Piper longum Linn)

Pippali is one of the Rasayana drugs described in Ayurveda It has Agnidipana and Amapachana actions and is helpful in the alleviation of Ama from the body which is the main pathological factor in Amavata ie rheumatoid arthritis

Pippali alleviates Ama the factor responsible for Balabhrmsha or development of autoimmune disorders in the body resulting in the correction in immune system activities Pippali has rasayana and immunomodulator actions Thus because of all these actions together it plays an important role in the Samprapti-vighatana of the Amavata ie rheumatoid arthritis

Ref Clinical evaluation of Vardhamana Pippali Rasayana in the management of Amavata (Rheumatoid

Arthritis) Anamika Soni1 Kalapi Patel2 and S N Gupta3

Pippali (Piper longum Linn)

Pippali is one of the Rasayana drugs described in Ayurveda It has Agnidipana and Amapachana actions and is helpful in the alleviation of Ama from the body which is the main pathological factor in Amavata ie rheumatoid arthritis

Pippali alleviates Ama the factor responsible for Balabhrmsha or development of autoimmune disorders in the body resulting in the correction in immune system activities Pippali has rasayana and immunomodulator actions Thus because of all these actions together it plays an important role in the Samprapti-vighatana of the Amavata ie rheumatoid arthritis

Ref Clinical evaluation of Vardhamana Pippali Rasayana in the management of Amavata (Rheumatoid

Arthritis) Anamika Soni1 Kalapi Patel2 and S N Gupta3

Shunthi(Zingiber officinale Roscoe)

Shunthi due to its Katu Rasa and

Ushna Virya is well known for

Vata-Shleshma Vibandhahara

Shunthi possesses the basic quality of

Deepan and Pachan properties which improve Jatharagni When

Jatharagni is improved it leads to the formation of Dhatus and

checks the formation of Ama

By virtue of Ushana Veerya it digests and absorbs the

vitiated Ama by its Shoshana Karma

Scientifically it has been proved that Shunthi possesses

active principles of gingerol dehydrozingerone and gingerdione

and they are potent inhibitors of prostaglandin synthesis indicating

the mechanism of an anti-arthritic effect

Ref Clinical studies on the role of sunthiguggulu yoga in the treatment of amavata - rheumatoid arthritis Kishore P KV Devi Das and S Banerjee

Guduchi(Tinospora cordifolia Willd)

Guduchi possesses the qualities of Tikta Kashaya Rasa

Madhur Vipak and Ushana Veerya Guduchi have the dual

action of Vata Shamana and Bruhana on the tissues

especially the Asthi Dhatu

Guduchi contains gycosides whose activity

resembles that of nonsteriodal anti-inflammatory agents

producing anti-inflammatory and anti-arthritic activities

Ref Clinical evaluation of Tinospora cordifolia in amavata and sandhigata vataMhaiskar VB DC Pandya and KB Karmarkar

Rasona(Allium cepa Linn)

Rasona is a well-known Vata and Kaphahara

It is also proved to have an anti-inflammatory effect

A concentrate having allicin and allinase alkaloid proved

effective in treating rheumatoid arthritis

Rasona is a rasayana according

to Bhavprakash and Madanpal and thus it is very useful for

treating the disease and also for maintaining the health of the

patients due to the chronic nature of the disease

Ref A comparative study ofRasona Rasnadi Ghanavati andSimhanadaGuggulu onAmavatawith special reference to Rheumatoid arthritis Raja Ram Mahto1 Alankruta R Dave2 and V D Shukla3

Guduchi(Tinospora cordifolia Willd)

Guduchi possesses the qualities of Tikta Kashaya Rasa

Madhur Vipak and Ushana Veerya Guduchi have the dual

action of Vata Shamana and Bruhana on the tissues

especially the Asthi Dhatu

Guduchi contains gycosides whose activity

resembles that of nonsteriodal anti-inflammatory agents

producing anti-inflammatory and anti-arthritic activities

Ref Clinical evaluation of Tinospora cordifolia in amavata and sandhigata vataMhaiskar VB DC Pandya and KB Karmarkar

Rasona(Allium cepa Linn)

Rasona is a well-known Vata and Kaphahara

It is also proved to have an anti-inflammatory effect

A concentrate having allicin and allinase alkaloid proved

effective in treating rheumatoid arthritis

Rasona is a rasayana according

to Bhavprakash and Madanpal and thus it is very useful for

treating the disease and also for maintaining the health of the

patients due to the chronic nature of the disease

Ref A comparative study ofRasona Rasnadi Ghanavati andSimhanadaGuggulu onAmavatawith special reference to Rheumatoid arthritis Raja Ram Mahto1 Alankruta R Dave2 and V D Shukla3

Rasona(Allium cepa Linn)

Rasona is a well-known Vata and Kaphahara

It is also proved to have an anti-inflammatory effect

A concentrate having allicin and allinase alkaloid proved

effective in treating rheumatoid arthritis

Rasona is a rasayana according

to Bhavprakash and Madanpal and thus it is very useful for

treating the disease and also for maintaining the health of the

patients due to the chronic nature of the disease

Ref A comparative study ofRasona Rasnadi Ghanavati andSimhanadaGuggulu onAmavatawith special reference to Rheumatoid arthritis Raja Ram Mahto1 Alankruta R Dave2 and V D Shukla3

Haridra(Curcuma longa Linn)

Curcuma longa commonly known as Turmeric has

antiseptic and anti-inflammatory properties Curcumin

an alkaloid isolated from this plant has anti-

inflammatory anti-arthritic and anti-rheumatic

properties

It also has beneficial effects on platelet

aggregation and vascular prostaglandin synthesis The

activation of the adrenohypophysial axis may be

responsible for inhibition of late arthritic changes

Ref Advances in research in Indian Medicine KN Udupa GN Chaturvedi and SN Tripathi

Dalbergia lanceolaria L

This is a tree of Leguminacae family found on the small hills throughout India The botanical description of the plant is available in wealth of indiaand has also been described by Kirtikar and Basu

This plant is popularly used for the treatment of arthritis as folk medicine The decoction of leaves and tender branches of the plant mixed with sugar and ghee is used every day for a month or so The seed oil has also been described to have anti-Rheumatic property

Ref Advances in research in Indian Medicine KN Udupa GN Chaturvedi and SN Tripathi

Semecarpus anacardium Linn

(Bhallataka)

It is tree of Anacardiacae family

found in the lower level of Himalayan range

It is popularly known as Marking nut

This is one of the potent drugs of

Indian system of medicine used for various

conditions it contains a highly irritant oil of

Phenolic nature in the pulp of the fruit

This drug is supposed to have powerful

action on gastro-intestinal tract It stimulates the

digestive mechanism

According to ayurveda involvement of

gastro-intestinal tract is primary in the aetiology of

amavata hence this drug was given a trial to assess

its role in the treatment of the same

Ref Bhallataka in management of rheumatoid arthritis (Amavata) A clinical and experimental

evidenceP Kishore SN Tripathi - Rheumatism 1966

Paedaria foetida Linn (prasarini)

It is a creeper of Rubiacae family having

an special pungent odour The root is quite thick

which is used for medicinal purpose

Extensive experimental and clinical

studies have been done on this drug the result have

been highly encouraging Oil processed with this drug

has also been recommended for Rheumatic diseases

Ref Advances in research in Indian Medicine KN Udupa GN Chaturvedi and SN Tripathi

Ricinus communis Linn (Erenda)

Eranda oil by virtue of its different pharmacological property

overcomes the pathology of amavata like ushna viryaamp vata

pacifying property helps in improving pain and inflammation

Ushna property also acts as deepana and potentiates agni thus

checking ama formation

Castor oil is very effective natural antiinflammatory

High vitamin E content contributes significantly to the

antiInflammatory properties of castor oil The natural vitamin E

present in castor oil has a number of tocopherol specific

moisturizing antiinflammatory ampantioxidant property Also

vitamin E contributes to improve microcirculation and UV

protection

Ref Effect Of Eranda Taila amp Ruksha (Baluka) Sweda On Biochemical Mediators In Rheumatoid Arthritis Mishra Pramod Kumar Rai NP

Commiphora mukul Hook(Guggulu)

The Sanskrit definition of the term guggul is one that protects

against diseases This attests to the wide respect and therapeutic

Ayurvedic applications for this botanical considered the most

important for the removal of ama toxic substances which

accumulate as a result of sluggish digestion and circulation

associated with a slowing of metabolism

Guggul is a resin the major ingredient in joint care

and immuno care that has been regarded as a remedy in Ayurvedic

medicine known to increase white blood cell count and to possess

strong immuno-modulating properties Guggul is one of the broad

spectrum health products with a wide range of benefits Ref Advances in research in Indian Medicine KN Udupa GN Chaturvedi and SN Tripathi

References

1Clinical evaluation of Vardhamana Pippali Rasayana in the management of Amavata (Rheumatoid

Arthritis)

Anamika Soni1 Kalapi Patel2 and S N Gupta3

2A comparative study of Rasona Rasnadi Ghanavati andSimhanada Guggulu on Amavata with

special reference to Rheumatoid arthritis

Raja Ram Mahto1 Alankruta R Dave2 and V D Shukla3

3Effect Of Eranda Taila amp Ruksha (Baluka) Sweda On Biochemical Mediators In Rheumatoid Arthritis Mishra Pramod Kumar Rai NP 4Clinical studies on the role of sunthiguggulu yoga in the treatment of amavata - rheumatoid

arthritis

Kishore P KV Devi Das and S Banerjee

5Clinical evaluation of Tinospora cordifolia in amavata and sandhigata vata

Mhaiskar VB DC Pandya and KB Karmarkar

6Management of Amavata with lsquoAmrita Ghritarsquo A clinical study

P S Lekurwale1 Kamlesh Pandey2 and P Yadaiah3

7Advances in research in Indian Medicine

KN Udupa GN Chaturvedi and SN Tripathi

8Mishra al UPJ 201302 (04) page20-22

9Panthulu Raghupathi Goud et alIJRAP 3 (1) Jan-Feb 2013

Dalbergia lanceolaria L

This is a tree of Leguminacae family found on the small hills throughout India The botanical description of the plant is available in wealth of indiaand has also been described by Kirtikar and Basu

This plant is popularly used for the treatment of arthritis as folk medicine The decoction of leaves and tender branches of the plant mixed with sugar and ghee is used every day for a month or so The seed oil has also been described to have anti-Rheumatic property

Ref Advances in research in Indian Medicine KN Udupa GN Chaturvedi and SN Tripathi

Semecarpus anacardium Linn

(Bhallataka)

It is tree of Anacardiacae family

found in the lower level of Himalayan range

It is popularly known as Marking nut

This is one of the potent drugs of

Indian system of medicine used for various

conditions it contains a highly irritant oil of

Phenolic nature in the pulp of the fruit

This drug is supposed to have powerful

action on gastro-intestinal tract It stimulates the

digestive mechanism

According to ayurveda involvement of

gastro-intestinal tract is primary in the aetiology of

amavata hence this drug was given a trial to assess

its role in the treatment of the same

Ref Bhallataka in management of rheumatoid arthritis (Amavata) A clinical and experimental

evidenceP Kishore SN Tripathi - Rheumatism 1966

Paedaria foetida Linn (prasarini)

It is a creeper of Rubiacae family having

an special pungent odour The root is quite thick

which is used for medicinal purpose

Extensive experimental and clinical

studies have been done on this drug the result have

been highly encouraging Oil processed with this drug

has also been recommended for Rheumatic diseases

Ref Advances in research in Indian Medicine KN Udupa GN Chaturvedi and SN Tripathi

Ricinus communis Linn (Erenda)

Eranda oil by virtue of its different pharmacological property

overcomes the pathology of amavata like ushna viryaamp vata

pacifying property helps in improving pain and inflammation

Ushna property also acts as deepana and potentiates agni thus

checking ama formation

Castor oil is very effective natural antiinflammatory

High vitamin E content contributes significantly to the

antiInflammatory properties of castor oil The natural vitamin E

present in castor oil has a number of tocopherol specific

moisturizing antiinflammatory ampantioxidant property Also

vitamin E contributes to improve microcirculation and UV

protection

Ref Effect Of Eranda Taila amp Ruksha (Baluka) Sweda On Biochemical Mediators In Rheumatoid Arthritis Mishra Pramod Kumar Rai NP

Commiphora mukul Hook(Guggulu)

The Sanskrit definition of the term guggul is one that protects

against diseases This attests to the wide respect and therapeutic

Ayurvedic applications for this botanical considered the most

important for the removal of ama toxic substances which

accumulate as a result of sluggish digestion and circulation

associated with a slowing of metabolism

Guggul is a resin the major ingredient in joint care

and immuno care that has been regarded as a remedy in Ayurvedic

medicine known to increase white blood cell count and to possess

strong immuno-modulating properties Guggul is one of the broad

spectrum health products with a wide range of benefits Ref Advances in research in Indian Medicine KN Udupa GN Chaturvedi and SN Tripathi

References

1Clinical evaluation of Vardhamana Pippali Rasayana in the management of Amavata (Rheumatoid

Arthritis)

Anamika Soni1 Kalapi Patel2 and S N Gupta3

2A comparative study of Rasona Rasnadi Ghanavati andSimhanada Guggulu on Amavata with

special reference to Rheumatoid arthritis

Raja Ram Mahto1 Alankruta R Dave2 and V D Shukla3

3Effect Of Eranda Taila amp Ruksha (Baluka) Sweda On Biochemical Mediators In Rheumatoid Arthritis Mishra Pramod Kumar Rai NP 4Clinical studies on the role of sunthiguggulu yoga in the treatment of amavata - rheumatoid

arthritis

Kishore P KV Devi Das and S Banerjee

5Clinical evaluation of Tinospora cordifolia in amavata and sandhigata vata

Mhaiskar VB DC Pandya and KB Karmarkar

6Management of Amavata with lsquoAmrita Ghritarsquo A clinical study

P S Lekurwale1 Kamlesh Pandey2 and P Yadaiah3

7Advances in research in Indian Medicine

KN Udupa GN Chaturvedi and SN Tripathi

8Mishra al UPJ 201302 (04) page20-22

9Panthulu Raghupathi Goud et alIJRAP 3 (1) Jan-Feb 2013

Semecarpus anacardium Linn

(Bhallataka)

It is tree of Anacardiacae family

found in the lower level of Himalayan range

It is popularly known as Marking nut

This is one of the potent drugs of

Indian system of medicine used for various

conditions it contains a highly irritant oil of

Phenolic nature in the pulp of the fruit

This drug is supposed to have powerful

action on gastro-intestinal tract It stimulates the

digestive mechanism

According to ayurveda involvement of

gastro-intestinal tract is primary in the aetiology of

amavata hence this drug was given a trial to assess

its role in the treatment of the same

Ref Bhallataka in management of rheumatoid arthritis (Amavata) A clinical and experimental

evidenceP Kishore SN Tripathi - Rheumatism 1966

Paedaria foetida Linn (prasarini)

It is a creeper of Rubiacae family having

an special pungent odour The root is quite thick

which is used for medicinal purpose

Extensive experimental and clinical

studies have been done on this drug the result have

been highly encouraging Oil processed with this drug

has also been recommended for Rheumatic diseases

Ref Advances in research in Indian Medicine KN Udupa GN Chaturvedi and SN Tripathi

Ricinus communis Linn (Erenda)

Eranda oil by virtue of its different pharmacological property

overcomes the pathology of amavata like ushna viryaamp vata

pacifying property helps in improving pain and inflammation

Ushna property also acts as deepana and potentiates agni thus

checking ama formation

Castor oil is very effective natural antiinflammatory

High vitamin E content contributes significantly to the

antiInflammatory properties of castor oil The natural vitamin E

present in castor oil has a number of tocopherol specific

moisturizing antiinflammatory ampantioxidant property Also

vitamin E contributes to improve microcirculation and UV

protection

Ref Effect Of Eranda Taila amp Ruksha (Baluka) Sweda On Biochemical Mediators In Rheumatoid Arthritis Mishra Pramod Kumar Rai NP

Commiphora mukul Hook(Guggulu)

The Sanskrit definition of the term guggul is one that protects

against diseases This attests to the wide respect and therapeutic

Ayurvedic applications for this botanical considered the most

important for the removal of ama toxic substances which

accumulate as a result of sluggish digestion and circulation

associated with a slowing of metabolism

Guggul is a resin the major ingredient in joint care

and immuno care that has been regarded as a remedy in Ayurvedic

medicine known to increase white blood cell count and to possess

strong immuno-modulating properties Guggul is one of the broad

spectrum health products with a wide range of benefits Ref Advances in research in Indian Medicine KN Udupa GN Chaturvedi and SN Tripathi

References

1Clinical evaluation of Vardhamana Pippali Rasayana in the management of Amavata (Rheumatoid

Arthritis)

Anamika Soni1 Kalapi Patel2 and S N Gupta3

2A comparative study of Rasona Rasnadi Ghanavati andSimhanada Guggulu on Amavata with

special reference to Rheumatoid arthritis

Raja Ram Mahto1 Alankruta R Dave2 and V D Shukla3

3Effect Of Eranda Taila amp Ruksha (Baluka) Sweda On Biochemical Mediators In Rheumatoid Arthritis Mishra Pramod Kumar Rai NP 4Clinical studies on the role of sunthiguggulu yoga in the treatment of amavata - rheumatoid

arthritis

Kishore P KV Devi Das and S Banerjee

5Clinical evaluation of Tinospora cordifolia in amavata and sandhigata vata

Mhaiskar VB DC Pandya and KB Karmarkar

6Management of Amavata with lsquoAmrita Ghritarsquo A clinical study

P S Lekurwale1 Kamlesh Pandey2 and P Yadaiah3

7Advances in research in Indian Medicine

KN Udupa GN Chaturvedi and SN Tripathi

8Mishra al UPJ 201302 (04) page20-22

9Panthulu Raghupathi Goud et alIJRAP 3 (1) Jan-Feb 2013

This drug is supposed to have powerful

action on gastro-intestinal tract It stimulates the

digestive mechanism

According to ayurveda involvement of

gastro-intestinal tract is primary in the aetiology of

amavata hence this drug was given a trial to assess

its role in the treatment of the same

Ref Bhallataka in management of rheumatoid arthritis (Amavata) A clinical and experimental

evidenceP Kishore SN Tripathi - Rheumatism 1966

Paedaria foetida Linn (prasarini)

It is a creeper of Rubiacae family having

an special pungent odour The root is quite thick

which is used for medicinal purpose

Extensive experimental and clinical

studies have been done on this drug the result have

been highly encouraging Oil processed with this drug

has also been recommended for Rheumatic diseases

Ref Advances in research in Indian Medicine KN Udupa GN Chaturvedi and SN Tripathi

Ricinus communis Linn (Erenda)

Eranda oil by virtue of its different pharmacological property

overcomes the pathology of amavata like ushna viryaamp vata

pacifying property helps in improving pain and inflammation

Ushna property also acts as deepana and potentiates agni thus

checking ama formation

Castor oil is very effective natural antiinflammatory

High vitamin E content contributes significantly to the

antiInflammatory properties of castor oil The natural vitamin E

present in castor oil has a number of tocopherol specific

moisturizing antiinflammatory ampantioxidant property Also

vitamin E contributes to improve microcirculation and UV

protection

Ref Effect Of Eranda Taila amp Ruksha (Baluka) Sweda On Biochemical Mediators In Rheumatoid Arthritis Mishra Pramod Kumar Rai NP

Commiphora mukul Hook(Guggulu)

The Sanskrit definition of the term guggul is one that protects

against diseases This attests to the wide respect and therapeutic

Ayurvedic applications for this botanical considered the most

important for the removal of ama toxic substances which

accumulate as a result of sluggish digestion and circulation

associated with a slowing of metabolism

Guggul is a resin the major ingredient in joint care

and immuno care that has been regarded as a remedy in Ayurvedic

medicine known to increase white blood cell count and to possess

strong immuno-modulating properties Guggul is one of the broad

spectrum health products with a wide range of benefits Ref Advances in research in Indian Medicine KN Udupa GN Chaturvedi and SN Tripathi

References

1Clinical evaluation of Vardhamana Pippali Rasayana in the management of Amavata (Rheumatoid

Arthritis)

Anamika Soni1 Kalapi Patel2 and S N Gupta3

2A comparative study of Rasona Rasnadi Ghanavati andSimhanada Guggulu on Amavata with

special reference to Rheumatoid arthritis

Raja Ram Mahto1 Alankruta R Dave2 and V D Shukla3

3Effect Of Eranda Taila amp Ruksha (Baluka) Sweda On Biochemical Mediators In Rheumatoid Arthritis Mishra Pramod Kumar Rai NP 4Clinical studies on the role of sunthiguggulu yoga in the treatment of amavata - rheumatoid

arthritis

Kishore P KV Devi Das and S Banerjee

5Clinical evaluation of Tinospora cordifolia in amavata and sandhigata vata

Mhaiskar VB DC Pandya and KB Karmarkar

6Management of Amavata with lsquoAmrita Ghritarsquo A clinical study

P S Lekurwale1 Kamlesh Pandey2 and P Yadaiah3

7Advances in research in Indian Medicine

KN Udupa GN Chaturvedi and SN Tripathi

8Mishra al UPJ 201302 (04) page20-22

9Panthulu Raghupathi Goud et alIJRAP 3 (1) Jan-Feb 2013

Paedaria foetida Linn (prasarini)

It is a creeper of Rubiacae family having

an special pungent odour The root is quite thick

which is used for medicinal purpose

Extensive experimental and clinical

studies have been done on this drug the result have

been highly encouraging Oil processed with this drug

has also been recommended for Rheumatic diseases

Ref Advances in research in Indian Medicine KN Udupa GN Chaturvedi and SN Tripathi

Ricinus communis Linn (Erenda)

Eranda oil by virtue of its different pharmacological property

overcomes the pathology of amavata like ushna viryaamp vata

pacifying property helps in improving pain and inflammation

Ushna property also acts as deepana and potentiates agni thus

checking ama formation

Castor oil is very effective natural antiinflammatory

High vitamin E content contributes significantly to the

antiInflammatory properties of castor oil The natural vitamin E

present in castor oil has a number of tocopherol specific

moisturizing antiinflammatory ampantioxidant property Also

vitamin E contributes to improve microcirculation and UV

protection

Ref Effect Of Eranda Taila amp Ruksha (Baluka) Sweda On Biochemical Mediators In Rheumatoid Arthritis Mishra Pramod Kumar Rai NP

Commiphora mukul Hook(Guggulu)

The Sanskrit definition of the term guggul is one that protects

against diseases This attests to the wide respect and therapeutic

Ayurvedic applications for this botanical considered the most

important for the removal of ama toxic substances which

accumulate as a result of sluggish digestion and circulation

associated with a slowing of metabolism

Guggul is a resin the major ingredient in joint care

and immuno care that has been regarded as a remedy in Ayurvedic

medicine known to increase white blood cell count and to possess

strong immuno-modulating properties Guggul is one of the broad

spectrum health products with a wide range of benefits Ref Advances in research in Indian Medicine KN Udupa GN Chaturvedi and SN Tripathi

References

1Clinical evaluation of Vardhamana Pippali Rasayana in the management of Amavata (Rheumatoid

Arthritis)

Anamika Soni1 Kalapi Patel2 and S N Gupta3

2A comparative study of Rasona Rasnadi Ghanavati andSimhanada Guggulu on Amavata with

special reference to Rheumatoid arthritis

Raja Ram Mahto1 Alankruta R Dave2 and V D Shukla3

3Effect Of Eranda Taila amp Ruksha (Baluka) Sweda On Biochemical Mediators In Rheumatoid Arthritis Mishra Pramod Kumar Rai NP 4Clinical studies on the role of sunthiguggulu yoga in the treatment of amavata - rheumatoid

arthritis

Kishore P KV Devi Das and S Banerjee

5Clinical evaluation of Tinospora cordifolia in amavata and sandhigata vata

Mhaiskar VB DC Pandya and KB Karmarkar

6Management of Amavata with lsquoAmrita Ghritarsquo A clinical study

P S Lekurwale1 Kamlesh Pandey2 and P Yadaiah3

7Advances in research in Indian Medicine

KN Udupa GN Chaturvedi and SN Tripathi

8Mishra al UPJ 201302 (04) page20-22

9Panthulu Raghupathi Goud et alIJRAP 3 (1) Jan-Feb 2013

Ricinus communis Linn (Erenda)

Eranda oil by virtue of its different pharmacological property

overcomes the pathology of amavata like ushna viryaamp vata

pacifying property helps in improving pain and inflammation

Ushna property also acts as deepana and potentiates agni thus

checking ama formation

Castor oil is very effective natural antiinflammatory

High vitamin E content contributes significantly to the

antiInflammatory properties of castor oil The natural vitamin E

present in castor oil has a number of tocopherol specific

moisturizing antiinflammatory ampantioxidant property Also

vitamin E contributes to improve microcirculation and UV

protection

Ref Effect Of Eranda Taila amp Ruksha (Baluka) Sweda On Biochemical Mediators In Rheumatoid Arthritis Mishra Pramod Kumar Rai NP

Commiphora mukul Hook(Guggulu)

The Sanskrit definition of the term guggul is one that protects

against diseases This attests to the wide respect and therapeutic

Ayurvedic applications for this botanical considered the most

important for the removal of ama toxic substances which

accumulate as a result of sluggish digestion and circulation

associated with a slowing of metabolism

Guggul is a resin the major ingredient in joint care

and immuno care that has been regarded as a remedy in Ayurvedic

medicine known to increase white blood cell count and to possess

strong immuno-modulating properties Guggul is one of the broad

spectrum health products with a wide range of benefits Ref Advances in research in Indian Medicine KN Udupa GN Chaturvedi and SN Tripathi

References

1Clinical evaluation of Vardhamana Pippali Rasayana in the management of Amavata (Rheumatoid

Arthritis)

Anamika Soni1 Kalapi Patel2 and S N Gupta3

2A comparative study of Rasona Rasnadi Ghanavati andSimhanada Guggulu on Amavata with

special reference to Rheumatoid arthritis

Raja Ram Mahto1 Alankruta R Dave2 and V D Shukla3

3Effect Of Eranda Taila amp Ruksha (Baluka) Sweda On Biochemical Mediators In Rheumatoid Arthritis Mishra Pramod Kumar Rai NP 4Clinical studies on the role of sunthiguggulu yoga in the treatment of amavata - rheumatoid

arthritis

Kishore P KV Devi Das and S Banerjee

5Clinical evaluation of Tinospora cordifolia in amavata and sandhigata vata

Mhaiskar VB DC Pandya and KB Karmarkar

6Management of Amavata with lsquoAmrita Ghritarsquo A clinical study

P S Lekurwale1 Kamlesh Pandey2 and P Yadaiah3

7Advances in research in Indian Medicine

KN Udupa GN Chaturvedi and SN Tripathi

8Mishra al UPJ 201302 (04) page20-22

9Panthulu Raghupathi Goud et alIJRAP 3 (1) Jan-Feb 2013

Commiphora mukul Hook(Guggulu)

The Sanskrit definition of the term guggul is one that protects

against diseases This attests to the wide respect and therapeutic

Ayurvedic applications for this botanical considered the most

important for the removal of ama toxic substances which

accumulate as a result of sluggish digestion and circulation

associated with a slowing of metabolism

Guggul is a resin the major ingredient in joint care

and immuno care that has been regarded as a remedy in Ayurvedic

medicine known to increase white blood cell count and to possess

strong immuno-modulating properties Guggul is one of the broad

spectrum health products with a wide range of benefits Ref Advances in research in Indian Medicine KN Udupa GN Chaturvedi and SN Tripathi

References

1Clinical evaluation of Vardhamana Pippali Rasayana in the management of Amavata (Rheumatoid

Arthritis)

Anamika Soni1 Kalapi Patel2 and S N Gupta3

2A comparative study of Rasona Rasnadi Ghanavati andSimhanada Guggulu on Amavata with

special reference to Rheumatoid arthritis

Raja Ram Mahto1 Alankruta R Dave2 and V D Shukla3

3Effect Of Eranda Taila amp Ruksha (Baluka) Sweda On Biochemical Mediators In Rheumatoid Arthritis Mishra Pramod Kumar Rai NP 4Clinical studies on the role of sunthiguggulu yoga in the treatment of amavata - rheumatoid

arthritis

Kishore P KV Devi Das and S Banerjee

5Clinical evaluation of Tinospora cordifolia in amavata and sandhigata vata

Mhaiskar VB DC Pandya and KB Karmarkar

6Management of Amavata with lsquoAmrita Ghritarsquo A clinical study

P S Lekurwale1 Kamlesh Pandey2 and P Yadaiah3

7Advances in research in Indian Medicine

KN Udupa GN Chaturvedi and SN Tripathi

8Mishra al UPJ 201302 (04) page20-22

9Panthulu Raghupathi Goud et alIJRAP 3 (1) Jan-Feb 2013

References

1Clinical evaluation of Vardhamana Pippali Rasayana in the management of Amavata (Rheumatoid

Arthritis)

Anamika Soni1 Kalapi Patel2 and S N Gupta3

2A comparative study of Rasona Rasnadi Ghanavati andSimhanada Guggulu on Amavata with

special reference to Rheumatoid arthritis

Raja Ram Mahto1 Alankruta R Dave2 and V D Shukla3

3Effect Of Eranda Taila amp Ruksha (Baluka) Sweda On Biochemical Mediators In Rheumatoid Arthritis Mishra Pramod Kumar Rai NP 4Clinical studies on the role of sunthiguggulu yoga in the treatment of amavata - rheumatoid

arthritis

Kishore P KV Devi Das and S Banerjee

5Clinical evaluation of Tinospora cordifolia in amavata and sandhigata vata

Mhaiskar VB DC Pandya and KB Karmarkar

6Management of Amavata with lsquoAmrita Ghritarsquo A clinical study

P S Lekurwale1 Kamlesh Pandey2 and P Yadaiah3

7Advances in research in Indian Medicine

KN Udupa GN Chaturvedi and SN Tripathi

8Mishra al UPJ 201302 (04) page20-22

9Panthulu Raghupathi Goud et alIJRAP 3 (1) Jan-Feb 2013

ACKNOWLEDGEMENT

I am thankful to TTD Principal SV

Ayurvedic college Tirupathi and my guide amp

Professor Dr M Paramkussh Rau garu for kind

support