Prepared by :Huner Sleman & Sarbast Mamand

Outline :

1. What is albumin?2. Functions of albumin?3. Serum albumin test:4. What Abnormal Results Mean?5. Drugs that effect albumin:6. Increase and decrease blood albumin:7. References:

What is albumin?

Human plasma protein, 66 Kda 80% of plasma proteins Negatively charged Synthesized in the liver Degradation is poorly

understood

Albumin is a protein made by the liver.Albumin is the major plasma protein.

What is albumin?

Functions of albumin?

Albumin helps move many small molecules through the blood, including bilirubin, calcium, progesterone, and medicines.

It plays an important role in keeping the fluid from the blood from leaking out into the tissues.

Free radical scavenging. Anti coagulatory effects. Acid-base balance.

Functions of albumin?

Serum albumin test:

A serum albumin test measures the amount of this protein in the clear liquid portion of the blood.

The health care provider may tell you to temporarily stop taking certain medicines that can affect the albumin.

Albumin can also be measured in the urine. The normal range is 3.4 to 5.4 g/dL.

What abnormal Results Mean

A lower than normal level of blood albumin may be a sign of:

Kidney diseases Liver disease (for example, hepatitis, or

cirrhosis that may cause ascites)

What abnormal Results Mean

A higher than normal level of blood albumin may be a sign of:

Water depletion Recent infusion of plasma or other albwmin

containing fluids.

Drugs that effect albumin:

Drugs that can increase albumin levels include:Anabolic steroids Drugs that AndrogensGrowth hormoneInsulin

Decreased blood albumin may due to:

After weight-loss surgery Crohn disease Low-protein diets Celiac disease Whipple disease

Increased blood albumin may be due to:

Dehydration. High protein diet. Having a tourniquet on for a long time when giving a blood

sample.

Risks: There is very little risk involved with having your blood taken.

Veins and arteries vary in size from one patient to another and from one side of the body to the other. Taking blood from some people may be more difficult than from others.

Other risks associated with having blood drawn are slight, but may include:Bleeding from where the needle was insertedFainting or feeling lightheadedHematoma (blood collecting under the skin)Infection (rare)

https://www.nlm.nih.gov/medlineplus/ency/article/003480.htm

https://labtestsonline.org/understanding/analytes/albumin/tab/test/

http://chemocare.com/chemotherapy/sideeffects/ hypoalbuminemialowalbumin. Aspx

http://bja.oxfordjournals.org/content/85/4/599.full

References:

Thank you