advanced non-invasive techniques in early detection of oral cancer
DESCRIPTION
ADVANCED NON-INVASIVE TECHNIQUES IN EARLY DETECTION OF ORAL CANCER. PRESENTED BY : Abhishek Ghosh 3 rd prof. B.D.S. Dr.R.Ahmed Dental college &Hospital GUIDED BY: Dr. Jay Gopal Ray H.O.D. Dept. Of Oral & Maxillofacial Pathology. ORAL CANCER : SOME DEADLY STATISTICS. - PowerPoint PPT PresentationTRANSCRIPT
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ADVANCED NON-INVASIVE TECHNIQUES IN EARLY DETECTION OF ORAL CANCER
PRESENTED BY: Abhishek Ghosh
3rd prof. B.D.S.Dr.R.Ahmed Dental
college &HospitalGUIDED BY:
Dr. Jay Gopal RayH.O.D.
Dept. Of Oral & Maxillofacial
Pathology
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ORAL CANCER : SOME DEADLY STATISTICS• Every hour 1 American dies of oral cancer
• Death rate is higher than cervical cancer
• 25%cases have no risk factor
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IMPORTANCE OF EARLY DETECTION
70% cases are diagnosed in late stagesIt leads to 5 year survival rate of 57% patientsOral cancer is 90% curable when detected early
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Why non-invasive techniques?• Painless and bloodless technique
• Biopsy is not possible in screening examination
• Helpful for follow-up cases
• Easy and simple for operator
• Patient’s medical status is fragile for biopsy• Patient refuses for biopsy
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EXFOLIATIVE CYTOLOGYIt is the histo-
pathological examination of
cells obtained by their physical
removal,followed by placement on glass-slide and
then appropriately stained.
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Preparation of ‘Pap-smear’
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VIZILITESimple painless non-invasive technology to visualize suspicious areas at earlier stages what we may not see by naked eyes .It’s based on the principle of CHEMILUMINESCENCE
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ACTION OF VIZILITEUnder vizilite
normal healthy tissue will
absorb light & appear dark.
Abnormal tissue will
appear white.
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HOW VIZILITE WORKS?Mouth
rinse
• Removes mucosal glycoprotei-n
• Increase N-C ratio
Light
stick
• Differentia-te between normal & abnormal tissue
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STEPSEncourage the
patient after routine exam
Rinse with 1%acetic acid for 30-60 sec
Bend outer light stick breaking
inner vial
Shake vigorously to mix content of
light stick
Insert it into open end of retractor &
assemble
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Make the room dark & re-examine the oral cavity with vizilite
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Intra-oral vital
stainingWith Toluidine blue helps to identify dysplastic and malignant mucous membrane in the oral cavity.
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STEPSDrying of mucosa with gauge
Mouth rinse with 1% T-blue for 1-2 min
1 min rinse with 1% acetic acid for decolourisation
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Maligna-nt cells have more metaboli-c rate
They retain the stain
Normal mucosa decolou-rises
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VIZILITE &TOLUIDINE BLUEVIZI-LITE
T-BLUE
SITE
FOR BIOPSY
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IR THERMOGRAPHYIt uses the heat of
our body to aid in making diagnosis.It is completely safe and uses no radiation.
2 parts-1.IR CAMERA
2.HIGH RESOLUTION COMPUTER
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MECHANISMDetection of breast cancer
Use in oral cancer –on way
Malignant tissue has more vascularity
Raised surface temperature
Detected by thermograph
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ADJUNCT TO SURGICAL BIOPSY
Confirm diagnosis
Biopsy
Visual examinati-on
Screening
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CONCLUSIONThese screening
techniques help in early detection of malignancy with an accuracy of 90 % and thus
%
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THANK YOU