adrenergic receptors

2
Adrenergic Receptors: A1 [a POMPous HEART can PROduce SPLINTERS] - generally all are contracted increase in... P - eripheral vasoconstriction O - utflow of Aq. humor M - ydriasis P - iloerection Heart - contractility PRO-state contraction (thereby C/I for patients with BPH) ~why A1 antag. is given instead SPLINTER ("Sphincter") - contraction A2 - generally inhibition of NTA release (autoreceptor) kaya... [DON'T RELEASE, PAPaLAG, SAMBASO, NO - Lipe InsuRens AQ"] ginawan ko kasi ng kwento: DONT RELEASE the person, kaso baka PAPaLAG. kaya SAMBASO na lang bigay mo sakin, kasi NO Lipe InsuRens AQ. (hahaha.. may sense ba?) anyways, ito na meaning niya: DON'T RELEASE - NTA PAPaLAG - PLatelet Plag or aggregation SAMBASO - constriction NO... NO... NO... Lipe - olysis Insu - lin Ren - in AQ - aqueous production (different mech. from A1 receptor) B1 - simple lang to kasi two organs lang: [H - JUGA!!] H - eart becomes PICHD (Postive Inotropic + CHronotropic + Dromotropic = inc. HR) Ju-Ga - JG cells - inc. RAAS (Na ret and VASOCONSTRICTION) B2 - [Hyop Ka+! .... RELAX BLU'T BROwN sugar..] Hyop Ka! - HypoKalemia RELAX (smooth muscles) lang si BLÚT BROWN BL - ood vessels UT - Uterine muscle / myometrium

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Pharmacology

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  • Adrenergic Receptors:

    A1 [a POMPous HEART can PROduce SPLINTERS] - generally all are contracted

    increase in...

    P - eripheral vasoconstriction

    O - utflow of Aq. humor

    M - ydriasis

    P - iloerection

    Heart - contractility

    PRO-state contraction (thereby C/I for patients with BPH) ~why A1 antag. is given instead

    SPLINTER ("Sphincter") - contraction

    A2 - generally inhibition of NTA release (autoreceptor) kaya...

    [DON'T RELEASE, PAPaLAG, SAMBASO, NO - Lipe InsuRens AQ"]

    ginawan ko kasi ng kwento: DONT RELEASE the person, kaso baka PAPaLAG. kaya SAMBASO na lang

    bigay mo sakin, kasi NO Lipe InsuRens AQ. (hahaha.. may sense ba?) anyways, ito na meaning niya:

    DON'T RELEASE - NTA

    PAPaLAG - PLatelet Plag or aggregation

    SAMBASO - constriction

    NO... NO... NO...

    Lipe - olysis

    Insu - lin

    Ren - in

    AQ - aqueous production (different mech. from A1 receptor)

    B1 - simple lang to kasi two organs lang: [H - JUGA!!]

    H - eart becomes PICHD (Postive Inotropic + CHronotropic + Dromotropic = inc. HR)

    Ju-Ga - JG cells - inc. RAAS (Na ret and VASOCONSTRICTION)

    B2 - [Hyop Ka+! .... RELAX BLU'T BROwN sugar..]

    Hyop Ka! - HypoKalemia

    RELAX (smooth muscles) lang si BLT BROWN

    BL - ood vessels

    UT - Uterine muscle / myometrium

  • BROwN - chial muscles

    Sugar - goes up... (lam niyo na ito: gluconeo, glycogenolysis)

    mydriasis (contraction of radial muscles) - outflow increases because of increase in the angle at the Canal of

    schlemm

    summary:

    A1 - a POMPous can PROduce SPLINTERS

    A2 - Don't RELEASE, PaPaLAG, SAMBASO, No Lipe InsuRens Aq

    B1 - H-JuGA!

    B2 - Hyop Ka!... Relax: BLT BROwN Sugar