actin depletion initiates events leading to granule secretion at the immunological synapse alex t....

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Actin Depletion Initiates Events Leading to Granule Secretion at the Immunological Synapse Alex T. Ritter, Yukako Asano, Jane C. Stinchcombe, N.M.G. Dieckmann, Bi-Chang Chen, C. Gawden-Bone, Schuyler van Engelenburg, Wesley Legant, Liang Gao, Michael W. Davidson, Eric Betzig, Jennifer Lippincott-Schwartz, Gillian M. Griffiths Immunity Volume 42, Issue 5, Pages 864-876 (May 2015) DOI: 10.1016/j.immuni.2015.04.013 Copyright © 2015 Elsevier Inc. Terms and Conditions

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Page 1: Actin Depletion Initiates Events Leading to Granule Secretion at the Immunological Synapse Alex T. Ritter, Yukako Asano, Jane C. Stinchcombe, N.M.G. Dieckmann,

Actin Depletion Initiates Events Leading to Granule Secretion at the Immunological Synapse 

Alex T. Ritter, Yukako Asano, Jane C. Stinchcombe, N.M.G. Dieckmann, Bi-Chang Chen, C. Gawden-Bone, Schuyler van Engelenburg, Wesley Legant, Liang Gao, Michael W. Davidson, Eric Betzig, Jennifer Lippincott-Schwartz, Gillian M. Griffiths  

Immunity Volume 42, Issue 5, Pages 864-876 (May 2015)

DOI: 10.1016/j.immuni.2015.04.013

Copyright © 2015 Elsevier Inc. Terms and Conditions

Page 2: Actin Depletion Initiates Events Leading to Granule Secretion at the Immunological Synapse Alex T. Ritter, Yukako Asano, Jane C. Stinchcombe, N.M.G. Dieckmann,

Figure 1

Immunity 2015 42, 864-876DOI: (10.1016/j.immuni.2015.04.013) Copyright © 2015 Elsevier Inc. Terms and Conditions

Page 3: Actin Depletion Initiates Events Leading to Granule Secretion at the Immunological Synapse Alex T. Ritter, Yukako Asano, Jane C. Stinchcombe, N.M.G. Dieckmann,

Figure 2

Immunity 2015 42, 864-876DOI: (10.1016/j.immuni.2015.04.013) Copyright © 2015 Elsevier Inc. Terms and Conditions

Page 4: Actin Depletion Initiates Events Leading to Granule Secretion at the Immunological Synapse Alex T. Ritter, Yukako Asano, Jane C. Stinchcombe, N.M.G. Dieckmann,

Figure 3

Immunity 2015 42, 864-876DOI: (10.1016/j.immuni.2015.04.013) Copyright © 2015 Elsevier Inc. Terms and Conditions

Page 5: Actin Depletion Initiates Events Leading to Granule Secretion at the Immunological Synapse Alex T. Ritter, Yukako Asano, Jane C. Stinchcombe, N.M.G. Dieckmann,

Figure 4

Immunity 2015 42, 864-876DOI: (10.1016/j.immuni.2015.04.013) Copyright © 2015 Elsevier Inc. Terms and Conditions

Page 6: Actin Depletion Initiates Events Leading to Granule Secretion at the Immunological Synapse Alex T. Ritter, Yukako Asano, Jane C. Stinchcombe, N.M.G. Dieckmann,

Figure 5

Immunity 2015 42, 864-876DOI: (10.1016/j.immuni.2015.04.013) Copyright © 2015 Elsevier Inc. Terms and Conditions

Page 7: Actin Depletion Initiates Events Leading to Granule Secretion at the Immunological Synapse Alex T. Ritter, Yukako Asano, Jane C. Stinchcombe, N.M.G. Dieckmann,

Figure 6

Immunity 2015 42, 864-876DOI: (10.1016/j.immuni.2015.04.013) Copyright © 2015 Elsevier Inc. Terms and Conditions

Page 8: Actin Depletion Initiates Events Leading to Granule Secretion at the Immunological Synapse Alex T. Ritter, Yukako Asano, Jane C. Stinchcombe, N.M.G. Dieckmann,

Figure 7

Immunity 2015 42, 864-876DOI: (10.1016/j.immuni.2015.04.013) Copyright © 2015 Elsevier Inc. Terms and Conditions

Page 9: Actin Depletion Initiates Events Leading to Granule Secretion at the Immunological Synapse Alex T. Ritter, Yukako Asano, Jane C. Stinchcombe, N.M.G. Dieckmann,

Immunity 2015 42, 864-876DOI: (10.1016/j.immuni.2015.04.013) Copyright © 2015 Elsevier Inc. Terms and Conditions