ABSTRACT

DRUG UTILIZATION STUDY IN HOSPITALIZED PATIENTS WITHPULMONAL TUBERCULOSIS AT Dr. RAMELAN NAVAL HOSPITAL

SURABAYA

The purpose of this study was to analyze the drug utilization in patients withpulmonal tuberculosis who were hospitalized during Juni 1st until December 31st

2005. This study include the demography of the tuberculosis patients, generalprofile of therapy in tuberculosis, the relationship between clinical/ laboratorydata and therapy, and drug interactions. The retrospective method was used in thisstudy with descriptive analysis in which the result then compared to guidelines fromDep. Kes. RI and WHO. The results of study were demography of patient revealedthat men suffering of tuberculosis was higher than woman (66% and 34%),respectively. The age of the patient of this study was the productive age higher thanothers age (57,9% vs 42,1%). 44,73% patients discharged from the hospital withrecovered condition, 47,36% with improved condition, 2,6 % with compulsion return,and 5,3 % were died in the hospital. The combination of anti tuberculosis used were:HRZE (44,7%), HRZ (31,6 %), HRE (10,6%), RZE (2,6%), H2E2 (2,6%), and HE(2,6%). The others treatment were treatment used to complication disease (to stophaemoptisis, secondary infection, anemia, and hypoalbuminemia), treatment usedto symptoms (to respiratory disturbance, GIT disturbance, antipyretic, andanalgesic), and treatment used to secondary degenerative disease (to control bloodpressure and blood glucose).

Keyword: Drug Utilization Study (DUS), Tuberculosis (TBC), Retrospectivestudy.