absorption, distribution, metabolism and elimination: part i
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Absorption, Distribution, Metabolism and Elimination: Part I. Joseph Graziano, Ph.D. Route of Administration Intramuscular: Intravenous:. Absorption Pattern Prompt from aqueous solutions, but slow and sustained from repository forms Immediate effects, since absorption is - PowerPoint PPT PresentationTRANSCRIPT
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Absorption, Distribution, Metabolism and Elimination:
Part I
Joseph Graziano, Ph.D.
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Major Routes of Drug Administration
Route of Administration
Intramuscular:
Intravenous:
Absorption Pattern
Prompt from aqueous solutions, but slow and sustained from repository forms
Immediate effects, since absorption is circumvented
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Major Routes of Drug Administration
Route of Administration
Oral Ingestion:
Subcutaneous:
Absorption Pattern
Variable; depends on many factors
Prompt from aqueous solutions, but slow and sustained from repository forms
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Other Routes of Administration
• Transdermal patch
• Inhalation
• Intra-arterial
• Intrathecal
• Topical: ocular, dermal, intranasal, intravaginal routes all lead to some systemic absorption
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