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A Strategy for Assessing and Managing Occupational Exposures Exposure Assessment Basic Characterization Start Unacceptabl e Acceptable Uncertain Control Measures Further Information Gathering Periodic Re- Assessment

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Page 1: A Strategy for Assessing and Managing Occupational Exposures Exposure Assessment Basic Characterization Start Unacceptable AcceptableUncertain Control

A Strategy for Assessing and Managing Occupational Exposures

Exposure Assessment

Basic CharacterizationStart

UnacceptableAcceptable Uncertain

Control Measures

Further Information Gathering

Periodic Re-Assessment

Page 2: A Strategy for Assessing and Managing Occupational Exposures Exposure Assessment Basic Characterization Start Unacceptable AcceptableUncertain Control

How do we develop the comprehensive metrology, instrumentation, and standards to

support a nanotechnology ESH program?

Page 3: A Strategy for Assessing and Managing Occupational Exposures Exposure Assessment Basic Characterization Start Unacceptable AcceptableUncertain Control

Exposure ManagementControl banding - concept

Low Dustiness Medium Dustiness High Dustiness

Hazard Group A

Small 1 1 1

Medium 1 1 2

Large 1 2 2

Hazard Group B

Small 1 1 1

Medium 1 2 2

Large 1 3 3

Hazard Group C

Small 1 1 2

Medium 2 3 3

Large 2 4 4

Hazard Group D

Small 2 2 3

Medium 3 4 4

Large 3 4 4

Hazard Group E

For all hazard group E substances, choose control approach 4

Parameters

Amount Used

Dustiness

Hazard Group (R-Phrase)

Control Approach1. General Ventilation

2. Engineering Control

3. Containment

4. Specialist Advice

www.ilo.orgNIOSH: TJ Lentz

Page 4: A Strategy for Assessing and Managing Occupational Exposures Exposure Assessment Basic Characterization Start Unacceptable AcceptableUncertain Control

A requirement from the U.K. Regulationson Control of Substances Hazardous to Health

(COSHH)

COSHH requires you to carry out health surveillance in the following circumstances:

• where employees are exposed to a substance linked to a particular disease or adverse health effect

• and there is a reasonable likelihood, under the conditions of the work, of that disease or effect occurring

• and it is possible to detect the disease or health effect.

Reference: COSHH: A brief guide to the Regulations What you need to know about the Control of Substances Hazardous to Health Regulations 2002 (COSHH), Health and safety Executive, INDG136rev3 04/05 C2000 (April 2005).

Page 5: A Strategy for Assessing and Managing Occupational Exposures Exposure Assessment Basic Characterization Start Unacceptable AcceptableUncertain Control

Comprehensive Industrial Hygiene Program Functional Elements

Exposure Monitoring

Engineering Controls

Hazardous Materials Management

Hazard Communication

Hearing Conservation

Personal Protective EquipmentMedical

Surveillance

Epidemiology Studies

Exposure Assessment

Page 6: A Strategy for Assessing and Managing Occupational Exposures Exposure Assessment Basic Characterization Start Unacceptable AcceptableUncertain Control

Particle CategoriesClasses of engineered nanoparticles

A. Spherical homogeneous

B. Fibrous homogeneous

C. Non-spherical homogeneous

D. Agglomerate homogeneous

E. Heterogeneous concentric

F. Heterogeneous distributed

G. Heterogeneous agglomerate

H. Active particle

I. Multifunctional particle

(not necessarily inclusive)Dr. Andrew D. Maynard: Woodrow Wilson International Center for Scholars

Page 7: A Strategy for Assessing and Managing Occupational Exposures Exposure Assessment Basic Characterization Start Unacceptable AcceptableUncertain Control

Particle CategoriesClasses of engineered nanoparticles

A. Spherical homogeneous

(not necessarily inclusive)Dr. Andrew D. Maynard: Woodrow Wilson International Center for Scholars

Page 8: A Strategy for Assessing and Managing Occupational Exposures Exposure Assessment Basic Characterization Start Unacceptable AcceptableUncertain Control

Particle CategoriesClasses of engineered nanoparticles

(not necessarily inclusive)Dr. Andrew D. Maynard: Woodrow Wilson International Center for Scholars

B. Fibrous homogeneous

Page 9: A Strategy for Assessing and Managing Occupational Exposures Exposure Assessment Basic Characterization Start Unacceptable AcceptableUncertain Control

Particle CategoriesClasses of engineered nanoparticles

(not necessarily inclusive)Dr. Andrew D. Maynard: Woodrow Wilson International Center for Scholars

C. Non-spherical homogeneous

Page 10: A Strategy for Assessing and Managing Occupational Exposures Exposure Assessment Basic Characterization Start Unacceptable AcceptableUncertain Control

Particle CategoriesClasses of engineered nanoparticles

(not necessarily inclusive)Dr. Andrew D. Maynard: Woodrow Wilson International Center for Scholars

D. Agglomerate homogeneous

Page 11: A Strategy for Assessing and Managing Occupational Exposures Exposure Assessment Basic Characterization Start Unacceptable AcceptableUncertain Control

Particle CategoriesClasses of engineered nanoparticles

(not necessarily inclusive)Dr. Andrew D. Maynard: Woodrow Wilson International Center for Scholars

E. Heterogeneous concentric

Page 12: A Strategy for Assessing and Managing Occupational Exposures Exposure Assessment Basic Characterization Start Unacceptable AcceptableUncertain Control

Particle CategoriesClasses of engineered nanoparticles

(not necessarily inclusive)Dr. Andrew D. Maynard: Woodrow Wilson International Center for Scholars

F. Heterogeneous distributed

Page 13: A Strategy for Assessing and Managing Occupational Exposures Exposure Assessment Basic Characterization Start Unacceptable AcceptableUncertain Control

Particle CategoriesClasses of engineered nanoparticles

(not necessarily inclusive)Dr. Andrew D. Maynard: Woodrow Wilson International Center for Scholars

G. Heterogeneous agglomerate

Page 14: A Strategy for Assessing and Managing Occupational Exposures Exposure Assessment Basic Characterization Start Unacceptable AcceptableUncertain Control

Particle CategoriesClasses of engineered nanoparticles

(not necessarily inclusive)Dr. Andrew D. Maynard: Woodrow Wilson International Center for Scholars

H. Active particle

Page 15: A Strategy for Assessing and Managing Occupational Exposures Exposure Assessment Basic Characterization Start Unacceptable AcceptableUncertain Control

Particle CategoriesClasses of engineered nanoparticles

(not necessarily inclusive)Dr. Andrew D. Maynard: Woodrow Wilson International Center for Scholars

I. Multifunctional particle

Page 16: A Strategy for Assessing and Managing Occupational Exposures Exposure Assessment Basic Characterization Start Unacceptable AcceptableUncertain Control

Particle CategoriesClasses of engineered nanoparticles

A. Spherical homogeneous

B. Fibrous homogeneous

C. Non-spherical homogeneous

D. Agglomerate homogeneous

E. Heterogeneous concentric

F. Heterogeneous distributed

G. Heterogeneous agglomerate

H. Active particle

I. Multifunctional particle

(not necessarily inclusive)Dr. Andrew D. Maynard: Woodrow Wilson International Center for Scholars

Page 17: A Strategy for Assessing and Managing Occupational Exposures Exposure Assessment Basic Characterization Start Unacceptable AcceptableUncertain Control
Page 18: A Strategy for Assessing and Managing Occupational Exposures Exposure Assessment Basic Characterization Start Unacceptable AcceptableUncertain Control

– Approaches to Safe Nanotechnology is a dynamic document about which NIOSH seeks public input, and that NIOSH will periodically update.

– Developing a comprehensive, centralized information management system across agencies and organizations would be a significant contribution

www.cdc.gov/niosh/topics/nanotech

Page 19: A Strategy for Assessing and Managing Occupational Exposures Exposure Assessment Basic Characterization Start Unacceptable AcceptableUncertain Control

The findings and conclusions of this presentation have not been formallydisseminated by the National Institute for Occupational Safety and Heathand should not be construed to represent any agency determination or policy.

Mention of company or product does not constitute endorsement by the Centers for Disease Control and Prevention or the National Institute for Occupational Safety and Health.

The assistance of many colleagues in the NIOSH Nanotechnology ResearchProgram and our partnering organizations is gratefully acknowledged.

[email protected] [email protected] 202-401-3737