a one-pot, two-step enzymatic synthesis of l-lactic acid from acetaldehyde

1
2002 hydroxycarboxylic acids hydroxycarboxylic acids (ether carboxylic acids) (acyclic compounds) and esters P 0280 46 - 089 A One-Pot, Two-Step Enzymatic Synthesis of L-Lactic Acid from Acetaldehyde. The title reaction is performed using a combination of reverse reaction of pyruvate decarboxylase and hydrogenation of pyruvate by lactic dehydrogenase. — (MIYAZAKI, MASAYA; OGINO, KAZUYA; SHIBUE, MITSUKUNI; NAKAMURA, HIROYUKI; MAEDA, HIDEAKI; Chem. Lett. (2002) 7, 758-759; Micro-space Chem. Lab., Natl. Inst. Adv. Ind. Sci Technol., Tosu, Saga 841, Japan; EN) 1

Upload: masaya-miyazaki

Post on 06-Jun-2016

213 views

Category:

Documents


1 download

TRANSCRIPT

Page 1: A One-Pot, Two-Step Enzymatic Synthesis of L-Lactic Acid from Acetaldehyde

2002 hydroxycarboxylic acids

hydroxycarboxylic acids (ether carboxylic acids) (acyclic compounds) and estersP 0280

46 - 089A One-Pot, Two-Step Enzymatic Synthesis of L-Lactic Acid fromAcetaldehyde. — The title reaction is performed using a combinationof reverse reaction of pyruvate decarboxylase and hydrogenation of pyruvateby lactic dehydrogenase. — (MIYAZAKI, MASAYA; OGINO, KAZUYA;SHIBUE, MITSUKUNI; NAKAMURA, HIROYUKI; MAEDA, HIDEAKI;Chem. Lett. (2002) 7, 758-759; Micro-space Chem. Lab., Natl. Inst. Adv. Ind.Sci Technol., Tosu, Saga 841, Japan; EN)

1