96 neurophysiologic intraoperative monitoring of somatosensory evoked potentials to detect...

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RESULTS: A total of 43 men (n22 DOBG, n21 ANTA) with a mean followup of 2015 months were identified. There were no significant differences between ANTA patients and DOBG patients in terms of age, previous treatment, location of the stricture within the bulbar urethra, or postoperative followup. ANTA was significantly more likely to be used for an obliterative type stricture (found in 50% versus 18% of those who underwent a DOBG, p0.043). There was no significant difference between groups in the use of bilateral buccal grafts; mean buccal length harvested was significantly less in the ANTA group (5.11.7cm) versus the DOBG group (6.01.9cm, p0.048). Overall, there were 6 patients with minor postoperative complications, and 1 patient with a postoperative periurethral ab- scess requiring conversion to a staged procedure. From the medical records, no new postoperative erectile dysfunction or chordee was reported in either group. There was no significant difference in post void dribbling between the two groups (ANTA 32% versus DOBG 25%, p0.65). Mean Qmax at last followup was similar in both groups (ANTA 2312 mL/sec versus DOBG 229 mL/sec, p0.92). Overall success rate was 93% and not statistically different between groups, with one ANTA patient and two DOBG patients requiring a post-urethroplasty dilation. CONCLUSIONS: The ANTA has results similar to DOBG in this population. Significantly less buccal graft is required when using the ANTA technique compared to traditional DOBG. ANTA can be used for obliterative type strictures that would have otherwise required a tran- sected AAU. Source of Funding: None 96 NEUROPHYSIOLOGIC INTRAOPERATIVE MONITORING OF SOMATOSENSORY EVOKED POTENTIALS TO DETECT NEUROLOGIC INJURIES DUE TO PATIENT POSITIONING Marc Manganiello*, Jay Shils, Carl Borromeo, Jill Buckley, Burlington, MA INTRODUCTION AND OBJECTIVES: To determine if intraop- erative somatosensory evoked potential (SSEP) monitoring may detect and prevent upper and lower extremity peripheral positioning related neuropathies in high risk urologic patients. METHODS: 64 patients underwent urethral reconstruction and intraoperative neuromonitoring by a single surgeon (JB) from March 2009 through August 2010. During the procedure, electrodes were placed at the wrist to stimulate the radial, ulnar and/or median nerve. The SSEP’s were recorded at the brachial plexus (for upper limb nerves), the cervical spine, and the cortex. The functional integrity of the pathway was monitored using the characteristic SSEP waveform parameters (amplitude and latency) from the various recording sites. The surgical and anesthesia teams were alerted when significant waveform changes (50% reduction in amplitude) occurred and re- positioning of the patient was performed. Patients were assessed postoperatively for neurologic deficits. RESULTS: 9 of the 64 patients in our cohort experienced significant intra-operative SSEP changes. The SSEP changes were detected on all upper extremity leads (1), all right upper extremity leads (2), right ulnar lead (1), left ulnar lead (3), and left median lead (2). 8 of these SSEP reductions were detected within ten minutes of the beginning of the case and returned to baseline with repositioning of the affected extremity. One event occurred after repositioning the patient during the case with correction bringing the SSEP back to baseline. In these 9 patients, there were no postoperative events. 2 of the 64 patients awoke with neurologic symptoms that were not detected intraoperatively. One experienced bilateral forearm numb- ness and hand extensor weakness, which resolved by the time of discharge. The second experienced right upper extremity sensory and motor weakness that required extensive neurologic assessment and prolonged physical therapy until 95% resolution at 3 months. No lower extremity neuropathies occurred. CONCLUSIONS: SSEP is a useful monitoring device to detect and prevent common position related neuropathies. Patients undergo- ing prolonged procedures or those at a high risk of a positioning related neuropathy may avoid postoperative neuropathies with SSEP monitor- ing. Detection of potential peripheral nerve damage largely occurred within the first ten minutes after positioning with resolution after re- positioning and no post-operative events. Source of Funding: None 97 EXTRAPERITONEAL BLADDER RUPTURES: COMPLICATIONS ASSOCIATED WITH OPERATIVE VERSUS NON-OPERATIVE MANAGEMENT AT THE TIME OF ANTERIOR PELVIC FIXATION OR ABDOMINAL EXPLORATION FOR OTHER INJURIES Michael Taylor*, William Brant, Chad Wallis, Molly McFadden, Salt Lake City, UT; Mark Stevens, Jay Bishoff, Murray, UT; Raminder Nirula, Jeremy Myers, Salt Lake City, UT INTRODUCTION AND OBJECTIVES: We sought to under- stand whether complication rates, in patients with extraperitoneal bladder rupture, were influenced by the management of these inju- ries with either an operative versus a non-operative approach at the time of anterior pelvis fixation or abdominal exploration for other injuries. METHODS: Patients with bladder injury were identified from the prospective trauma registry from all designated trauma 1 hospitals in Utah from 1996 –2010. Multiple patient data points were collected pertaining to injury presentation, management, and outcomes. Patients were excluded from our study if they had any component of intraperi- toneal bladder injury. RESULTS: A total of 259 patients were identified with possi- ble lower urinary tract injury, 121 of these patients had bladder injury, and 73 of these bladder injuries were extraperitoneal. The mean age of the patients was 38.4 years. The predominant mech- anism of injury was blunt trauma (93.2%) and the mean injury severity score was 24.3. Concomitant injuries included pelvic frac- ture in 64 (87.7%), solid organ injury in 19 (26.0%), and urethral injury in 10 (13.7%). 63 patients had bladder specific followup to rule out persistent urinary leak; the remaining patients died or had no radiologic follow up of their injury. The rate of persistent leak, in all patients with extraperitoneal injuries, with operative versus conser- vatively managed cases, was 5.6% (1/18) and 17.7% (8/45) (p0.04). At the time of anterior pelvic fixation, operative versus conservative management was associated with persistent leak in 12.5% (1/8) and 20.0% (2/10) (P1.0). During abdominal explora- tion for other injuries, operative versus conservative management of bladder injury was associated with persistent leak in 0% (0/6) and 16.7% (1/6) (P0.44). CONCLUSIONS: Extraperitoneal bladder injuries had a non- significant trend to have lower rates of persistent urinary leak when they were managed operatively. This trend was found in the entire cohort, as well as at the time of anterior pelvic fixation or abdominal exploration for other injuries. This finding was the stimulus for an ongoing multi-institutional analysis of bladder injury to determine if this trend is significant with a greater number of patients. Given this finding, trauma surgeons should consider operative management of extraperitoneal bladder injury at the time of anterior pelvic fixation or abdominal exploration. Source of Funding: None Vol. 185, No. 4, Supplement, Saturday, May 14, 2011 THE JOURNAL OF UROLOGY e41

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Page 1: 96 NEUROPHYSIOLOGIC INTRAOPERATIVE MONITORING OF SOMATOSENSORY EVOKED POTENTIALS TO DETECT NEUROLOGIC INJURIES DUE TO PATIENT POSITIONING

RESULTS: A total of 43 men (n�22 DOBG, n�21 ANTA) witha mean followup of 20�15 months were identified. There were nosignificant differences between ANTA patients and DOBG patientsin terms of age, previous treatment, location of the stricture withinthe bulbar urethra, or postoperative followup. ANTA was significantlymore likely to be used for an obliterative type stricture (found in 50%versus 18% of those who underwent a DOBG, p�0.043). There wasno significant difference between groups in the use of bilateralbuccal grafts; mean buccal length harvested was significantly less inthe ANTA group (5.1�1.7cm) versus the DOBG group (6.0�1.9cm,p�0.048). Overall, there were 6 patients with minor postoperativecomplications, and 1 patient with a postoperative periurethral ab-scess requiring conversion to a staged procedure. From the medicalrecords, no new postoperative erectile dysfunction or chordee wasreported in either group. There was no significant difference in postvoid dribbling between the two groups (ANTA 32% versus DOBG25%, p�0.65). Mean Qmax at last followup was similar in bothgroups (ANTA 23�12 mL/sec versus DOBG 22�9 mL/sec, p�0.92).Overall success rate was 93% and not statistically different betweengroups, with one ANTA patient and two DOBG patients requiring apost-urethroplasty dilation.

CONCLUSIONS: The ANTA has results similar to DOBG in thispopulation. Significantly less buccal graft is required when using theANTA technique compared to traditional DOBG. ANTA can be used forobliterative type strictures that would have otherwise required a tran-sected AAU.

Source of Funding: None

96NEUROPHYSIOLOGIC INTRAOPERATIVE MONITORING OFSOMATOSENSORY EVOKED POTENTIALS TO DETECTNEUROLOGIC INJURIES DUE TO PATIENT POSITIONING

Marc Manganiello*, Jay Shils, Carl Borromeo, Jill Buckley,Burlington, MA

INTRODUCTION AND OBJECTIVES: To determine if intraop-erative somatosensory evoked potential (SSEP) monitoring may detectand prevent upper and lower extremity peripheral positioning relatedneuropathies in high risk urologic patients.

METHODS: 64 patients underwent urethral reconstruction andintraoperative neuromonitoring by a single surgeon (JB) from March2009 through August 2010. During the procedure, electrodes wereplaced at the wrist to stimulate the radial, ulnar and/or median nerve.The SSEP’s were recorded at the brachial plexus (for upper limbnerves), the cervical spine, and the cortex. The functional integrity ofthe pathway was monitored using the characteristic SSEP waveformparameters (amplitude and latency) from the various recording sites.The surgical and anesthesia teams were alerted when significantwaveform changes (50% reduction in amplitude) occurred and re-positioning of the patient was performed. Patients were assessedpostoperatively for neurologic deficits.

RESULTS: 9 of the 64 patients in our cohort experiencedsignificant intra-operative SSEP changes. The SSEP changes weredetected on all upper extremity leads (1), all right upper extremityleads (2), right ulnar lead (1), left ulnar lead (3), and left median lead(2). 8 of these SSEP reductions were detected within ten minutes ofthe beginning of the case and returned to baseline with repositioningof the affected extremity. One event occurred after repositioning thepatient during the case with correction bringing the SSEP back tobaseline. In these 9 patients, there were no postoperative events. 2of the 64 patients awoke with neurologic symptoms that were notdetected intraoperatively. One experienced bilateral forearm numb-ness and hand extensor weakness, which resolved by the time ofdischarge. The second experienced right upper extremity sensoryand motor weakness that required extensive neurologic assessmentand prolonged physical therapy until 95% resolution at 3 months. Nolower extremity neuropathies occurred.

CONCLUSIONS: SSEP is a useful monitoring device to detectand prevent common position related neuropathies. Patients undergo-ing prolonged procedures or those at a high risk of a positioning relatedneuropathy may avoid postoperative neuropathies with SSEP monitor-ing. Detection of potential peripheral nerve damage largely occurredwithin the first ten minutes after positioning with resolution after re-positioning and no post-operative events.

Source of Funding: None

97EXTRAPERITONEAL BLADDER RUPTURES: COMPLICATIONSASSOCIATED WITH OPERATIVE VERSUS NON-OPERATIVEMANAGEMENT AT THE TIME OF ANTERIOR PELVICFIXATION OR ABDOMINAL EXPLORATION FOR OTHERINJURIES

Michael Taylor*, William Brant, Chad Wallis, Molly McFadden, SaltLake City, UT; Mark Stevens, Jay Bishoff, Murray, UT; RaminderNirula, Jeremy Myers, Salt Lake City, UT

INTRODUCTION AND OBJECTIVES: We sought to under-stand whether complication rates, in patients with extraperitonealbladder rupture, were influenced by the management of these inju-ries with either an operative versus a non-operative approach at thetime of anterior pelvis fixation or abdominal exploration for otherinjuries.

METHODS: Patients with bladder injury were identified from theprospective trauma registry from all designated trauma 1 hospitals inUtah from 1996–2010. Multiple patient data points were collectedpertaining to injury presentation, management, and outcomes. Patientswere excluded from our study if they had any component of intraperi-toneal bladder injury.

RESULTS: A total of 259 patients were identified with possi-ble lower urinary tract injury, 121 of these patients had bladderinjury, and 73 of these bladder injuries were extraperitoneal. Themean age of the patients was 38.4 years. The predominant mech-anism of injury was blunt trauma (93.2%) and the mean injuryseverity score was 24.3. Concomitant injuries included pelvic frac-ture in 64 (87.7%), solid organ injury in 19 (26.0%), and urethralinjury in 10 (13.7%). 63 patients had bladder specific followup to ruleout persistent urinary leak; the remaining patients died or had noradiologic follow up of their injury. The rate of persistent leak, in allpatients with extraperitoneal injuries, with operative versus conser-vatively managed cases, was 5.6% (1/18) and 17.7% (8/45)(p�0.04). At the time of anterior pelvic fixation, operative versusconservative management was associated with persistent leak in12.5% (1/8) and 20.0% (2/10) (P�1.0). During abdominal explora-tion for other injuries, operative versus conservative management ofbladder injury was associated with persistent leak in 0% (0/6) and16.7% (1/6) (P�0.44).

CONCLUSIONS: Extraperitoneal bladder injuries had a non-significant trend to have lower rates of persistent urinary leak whenthey were managed operatively. This trend was found in the entirecohort, as well as at the time of anterior pelvic fixation or abdominalexploration for other injuries. This finding was the stimulus for anongoing multi-institutional analysis of bladder injury to determine ifthis trend is significant with a greater number of patients. Given thisfinding, trauma surgeons should consider operative management ofextraperitoneal bladder injury at the time of anterior pelvic fixation orabdominal exploration.

Source of Funding: None

Vol. 185, No. 4, Supplement, Saturday, May 14, 2011 THE JOURNAL OF UROLOGY� e41