VULVOVAGINAL VULVOVAGINAL CANDIDIASISCANDIDIASIS

DefinitionDefinition

Vulvovaginal candidiasis (VVC)Vulvovaginal candidiasis (VVC)

An infection epithelium of vagina An infection epithelium of vagina

caused by the yeast-like fungus caused by the yeast-like fungus

Candida albicans Candida albicans or occasionally or occasionally

by other species of candidaby other species of candida

EpidemiologyEpidemiology

• VVC VVC females >>females >>

• Estimated rate Estimated rate 70 – 75%.70 – 75%.

• Recurrence Recurrence 40 – 50%.40 – 50%.

• Occur in all age especially 15-39 Occur in all age especially 15-39

years oldyears old

EtiologyEtiology Candida albicans is the Candida albicans is the

most often organismmost often organism

85 - 90% of yeast85 - 90% of yeast strains strains

isolated from the vagina isolated from the vagina

Candida albicans.Candida albicans.

Predisposing FactorsPredisposing Factors

1.1. Pregnancy.Pregnancy.

2.2. Contraceptives.Contraceptives.

3.3. Diabetes mellitus.Diabetes mellitus.

4.4. Antibiotics.Antibiotics.

5.5. Behavioral factors.Behavioral factors.

6.6. Miscellaneous.Miscellaneous.

Source of InfectionSource of Infection

1.1. Intestinal reservoir.Intestinal reservoir.

2.2. Sexual transmission.Sexual transmission.

3.3. Relapse.Relapse.

Clinical Clinical

ManifestationsManifestations

1.1. Acute pruritus & vaginal Acute pruritus & vaginal

discharge, discharge, areare t the usual he usual

presenting complaints.presenting complaints.

2.2. Vaginal soreness, Irritation, Vaginal soreness, Irritation,

vulvar burning, dysparemia & vulvar burning, dysparemia &

external are commonly external are commonly

present.present.

Odor, if present, is minimal & Odor, if present, is minimal &

inoffensive.inoffensive.

3.3. Erythema & swelling of the Erythema & swelling of the

labia & vulva Often with labia & vulva Often with

discrete pustulopapular discrete pustulopapular

peripheral lesions. peripheral lesions.

DiagnosisDiagnosis

1.1. Anamnesis.Anamnesis.

2.2. Physical exam.Physical exam.

3.3. Microscopic exam. of vaginal Microscopic exam. of vaginal

secretions secretions yeast with hypae or yeast with hypae or

pseudohyphaepseudohyphae

Differential diagnosisDifferential diagnosis

• Vaginal trichomoniasisVaginal trichomoniasis

• Bacteral vaginosisBacteral vaginosis

TreatmentTreatment

1.1. Sistemik therapySistemik therapy

Itraconazole 2 x 200 mg a once.Itraconazole 2 x 200 mg a once.

Fluconazole 150 mg SDFluconazole 150 mg SD

2. Topical agents 2. Topical agents azole agents azole agents

Adjuvant :Adjuvant :

Treatment of male Treatment of male

sexual partnerssexual partners