9 eurocare lutz

7/29/2019 9 Eurocare Lutz

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Survival in Europe (http://www.eurocare.it/


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EUROCARE

EUROPEAN CANCER REGISTRY BASED STUDY ONSURVIVAL AND CARE OF CANCER PATIENTS

EUROCARE is the widest collaborative research project on

cancer survival in Europe.The project started in 1989 under the initiative of tworesearch institutes, Istituto Nazionale Tumori (Milan, Italy)www.istitutotumori.mi.it and Istituto Superiore di Sanit(Rome, Italy) www.iss.it, with the participation of a largenumber of population-based Cancer Registries throughout

Europe.


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EUROCARE

EUROPEAN CANCER REGISTRY BASED STUDY ON

SURVIVAL AND CARE OF CANCER PATIENTS

Aims of the study wer and still are: to provide an updated

description of cancer survival time trends and differences

across European countries, to measure cancer prevalence,

and to study patterns of care of cancer patients.


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EUROCARE 1-4

Project Nb cases Nb CR's Nb cancer(period) / Nb countries sites

EUROCARE-1 800,000 30 / 12 27(1978 > 84)

EUROCARE-2 1,300.000 45 / 17 42(1985 > 89)

EUROCARE-3 1,800,000 56 / 22 42

(1990 > 94)

EUROCARE-4 2,900,000 90 / 22 44(1995-99 > 2002)


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EUROCARE-3 & 4

Geographiccoverage

22 countries90 CRs

UK (England, Scotland, Wales)Nordic countriesSouth and West EuropeEastern Europe


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EUROCARE 5

The fifth and current edition, EUROCARE-5, includes dataon more than 21 million cancer diagnoses provided by 116Cancer Registries in 30 European countries.

Aims :

To update the existing EUROCARE data bank, byincluding data of patients diagnosed up to 2007. Follow upwill be updated to the most recent possible dates (e.g. on31/12/2008) in order to analyse both long and short termsurvival rates of cases diagnosed more recently.

To analyse survival of cancer patients by means ofconventional and more innovative methods: e.g. cohortrelative survival; period survival analysis to estimatesurvival of patients with recent diagnosis; mixture survivalmodel to estimate the proportion of patients cured.


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EUROCARE 5

To compare diagnostic and therapeutic procedures forcancer patients in Italy with those in other Europeancountries at high survival by means of high resolutionstudies (HR).

To increase and promote the use of cancer survivalregistry data. The EUROCARE results will be diffused amongthe medical, public health and scientific communities, tothe public in general, to tumour patients and to healthplanners.


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EUROCARE-5

Geographiccoverage

30 countries116 CRs


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Countries ranked by survival, colored according their TNEH*0 20 40 60 80 100

SWITZERLAND

SWEDEN

NORWAY

FINLAND

FRANCE

GERMANY

BELGIUM

NETHERLAND

ICELAND

AUSTRIA

ITALY

SPAIN

EU4 POOL

UK NORTH IRELAND

MALTA

UK SCOTLAND

PORTUGAL

IRELAND

UK WALES

UK ENGLAND

DENMARK

SLOVENIA

CZECH

POLAND

EUROCARE-4 1995-99Five-year Age Standardised Relative survivalAll cancers

* TNEH:

Total

NationalExpenditure

for Health


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All cancers combined (EUROCARE 4)

5-year age-adj. relative survival trend in male

8.5

7.5

10.5

6.7

12.1

6.6

8.9

8.8

6.3

7.9

9.2

8.7

4.5

7.2

5.2

3.5

6.6

-2.3

1.8

0 10 20 30 40 50 60

Iceland

Sweden

Swiss

Dutch

French

German

Norway

Finland

Spanish

Europe

Italian

English

Denmark

Wales

Scotland

Slovenia

Estonia

Slovakia

Polish

Relative survival

1984

1993 -1984

8.0

6.5

5.2

9.5

6.4

4.5

4.7

7.4

7.5

7.5

6.4

3.9

4.5

4.0

6.8

7.3

6.3

3.9

0 10 20 30 40 50 60

French

Swiss

Sweden

Dutch

Spanish

German

Finland

Iceland

Norvay

ItalianEurope

English

Slovenia

Wales

Scotland

Slovakia

Estonia

Polish

Relative survival

1984

1993 -1984

5-year age-adj. relative survival trend in female


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EUROCARE-4 1995-99Five-year Age Standardised Relative survivalcolorectum cancer

EUROCARE-4 1995-99

Five-year Age standardised survival by regions

0 20 40 60 80 100

DENMARK

FINLAND

ICELAND

NORWAY

SWEDEN

IRELAND

UK ENGLAND

UK NORTH IRELAND

UK SCOTLAND

UK WALES

AUSTRIA

BELGIUM

FRANCE

GERMANY

ITALY

MALTA

NETHERLAND

PORTUGAL

SPAIN

SWITZERLAND

CZECH

POLAND

SLOVENIA

EU4 POOL

C

o

l

o

r

e

c

t

um

countries grouped by region countries ranked by TNEH

five-year AAS by TNHE -colorecum

0 20 40 60 80 100

SWITZERLAND

GERMANY

NORWAY

ICELAND

FRANCE

DENMARK

BELGIUM

NETHERLAND

SWEDEN

AUSTRIA

ITALY

UK ENGLAND

UK NORTH IRELAND

UK SCOTLAND

UK WALES

MALTA

FINLANDIRELAND

SPAIN

PORTUGAL

CZECH

POLAND

SLOVENIA

EU4 POOL


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EUROCARE-4: 5-year survival of lung cancer patients

0 20 40 60 80 100

DENMARK

FINLAND

ICELAND

NORWAY

SWEDEN

IRELAND

UK ENGLAND

UK NORTH IRELAND

UK SCOTLAND

UK WALES

AUSTRIA

BELGIUM

FRANCE

GERMANY

ITALY

MALTA

NETHERLAND

PORTUGAL

SPAIN

SWITZERLAND

CZECH

POLAND

SLOVENIA

EU4 POOL

L

u

n

g


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EUROCARE-4: 5-year survival of breast cancer patients

0 20 40 60 80 100

DENMARKFINLAND

ICELAND

NORWAY

SWEDEN

IRELAND

UK ENGLAND

UK NORTH IRELAND

UK SCOTLAND

UK WALES

AUSTRIA

BELGIUM

FRANCE

GERMANY

ITALY

MALTA

NETHERLAND

PORTUGAL

SPAIN

SWITZERLAND

CZECH

POLAND

SLOVENIA

EU4 POOL

B

r

ea

s

t


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8588868581

7882

78 78 72

0

20

40

60

80

100

15-44 45-54 55-64 65-74 75-99

Age at diagnosis (years)

Relatives

urvival(%)

USA (SEER)

Europe (EUROCARE)

Breast cancer, five-year survival by ageUSA vs. Europe, women diagnosed 1990-94


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Relative excess risk of death of women diagnosed withbreast cancerin Europe (EUROCARE) vs. US (SEER), 1990-92

Model 1 Model 2 Model 3age

follow-up+

stage+

n examinednodes

SEER

EUROCARE

1

1.37*

1

1.12*

1

1.07

Age :


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0102030405060708090

100

83-85 86-88 89-91 92-94

Testis

OropharynxOvary

OesophagusLung

LiverPancreas

ThyroidCorpus

MelanomaBreast Hodgkin

,Bladder LarynxCervixProstateKidneyOralRectumNHL Colon

HypopharynxStomachBrain

EUROCARE : 5-year relative survival trends 1983-94


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The cancer survival gap between elderly andmiddle aged patients in Europe is widening


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The advantage of women in cancer survival


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The cure of cancer:A European perspective


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3

4

5

7

6


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