62 A case of 47,XXY/46,XY Klinefelter syndrome

Download 62 A case of 47,XXY/46,XY Klinefelter syndrome

Post on 19-Sep-2016

214 views

Category:

Documents

1 download

TRANSCRIPT

  • Abstracts

    during the short-term follow-up, with 6 cystic fat nodules.The satisfaction rate for sexual function, morphology andglobal state were 79.8%, 78.9%, and 91.7%.Conclusions: Our technique shows very effective short-term outcomes and patients satisfaction without seriouscomplications.

    62A case of 47,XXY/46,XY Klinefelter syndrome

    H. Masuda1, Y. Katsuoka2. 1Aino Hospital, 2 Osaka MedicalCollege, Japan

    Klinefelter syndrome represents the most commonlyfound human sex chromosomal abnormality. It ischaracterized by small, rm testes with hyalinizationof the seminiferous tubules, elevated gonadotropinsand azoospermia. Males with Klinefelter syndrome mayhave a 47,XXY or a mosaic 47,XXY/46,XY constitutionalkaryotype and varying degrees of spermatogenic failure.Mosaicism 47,XXY/46,XX with clinical features suggestiveof Klinefelter syndrome is very rare. We report herea case of a mosaic 47,XXY/46,XX infertile male. Thepatient was a 31-year-old male. Physical examinationrevealed perfect male-type of genitalia, almost normalpenis and bilateral small testicles, being 1.0 2.0 1.0 cmsized for the right and 1.0 2.0 1.0 cm for the left.Chromosome analysis by means of culture of peripheralblood lymphocytes revealed twokinds of 46 chromosomesand of 47 chromosomes. The genotype of the former wasXX and of the later was XXY, making XX/XXY mosaicism.Testicular sperm extraction was performed, but wecould nd the sperm in microdissection testicular spermextraction procedure. Histologically the testicle showedatrophy of seminiferous tubules with hyalinizaition ofthe canaliculi. No spermatogenesis was observed at all.

    63Coenzyme Q10 treatment foroligoasthenoteratozoospemia in infertile men withvaricoceleY. Kobori, H. Okada, G. Arai, S. Soh, H. Yagi. DokkyoMedical University Koshigaya Hospital, Department of Urology,Japan

    Objective: To evaluate the effectiveness of coenzyme Q10treatment in improving semen quality in men who havevaricocele with infertility.Patients: Sixty-nine infertile patients (2151 years of age)with the following baseline sperm selection criteria:concentration

Recommended

View more >