Childrens epilepsy:5 challenges for QS dev

Why QS 1?

Why QS 2?

Why QS 3?

Challenge 1: medication + seizure

Tegretol (carbamazepine) -> mood changesKeppra (levitiracetam)Depakine (valproaat) -> fatTopamax (topiramate) -> cognitive failsDiphantoine (Diphantoïne-Z , Epanutin, Fenytoïne) -> unhealthyMogadoneTrileptal (oxcarbazepine)Frisium (clobazam)Lamictal (lamatrogine) -> mood changes + tired + feverTemesta -> addictiveOspolot (sultiam)ValiumVimpat (lacosamide)

Seizuretracker.com

Challenge 2: Adherence

Challenge 3: nightly seizure tracking

• Current practice: LOL!

• MyZeo (sleep tracking - inpractical)

• Fitbit (sleep tracking - inpractical)

• Fitbit flex (sleep tracking - easy, but confusing)

• Jawbone UP (sleep tracking – testing + IFTTT)

• Dlink camera DCS-5020L

• MyBasis + Beddit: ordered & untested

Challenge 4A: medical info

• Video EEG (2011 + 2013)• EEG (… + 2013)• FDG-PET (2013)• MRI (… + 2013)• SISCOM• EEG-fMRI (2013)• Interictal EEG (2013)• Ictal SPECT (2013)• MEG (2013)• Appointments + feedback + results + notes

Challenge 4B: circumstantial info

• Food, mood, stress, …

• Overlay por favor

• Objective translation

Challenge 5: seizure alert

• Smart-monitor

• Epi care 3000

GO TO WORK!

… Oh wait …

Miscellanous Experimental info

• Neurolink has developed a drug-device combination therapy for the treatment of epilepsy. Link

• The Neurosigma Monarch is indicated as an adjunctive treatment of epilepsy link

• Wave’s wireless monitoring aims to manage epilepsy link

• The Epicenter team tackled the problem of controlling epileptic seizures through diet and biofeedback. Link

• The epilepsy detection wristband carries two kinds of sensors link

• @bart