Climate change foreseen for the next several decades of the 21st century over the European region is expected to alter air pollution and the effi ciency of subsequent abatement measures, and may lead to migration of new invasive allergenic plant species. The complex interplay across these multiple stressors might exacerbate the overall eff ect of environmental change on allergies in synergistic ways that are diffi cult to assess from a single discipline perspective. It is therefore neces-sary to develop an integrated and cross-disciplinary approach to assess health risks arising from environmental change and to design suitable adaptation policies.

The main aim of ATOPICA is to establish quantitative models of allergic disease to environmen-tal stressors to be used for pro-jections of future disease risk. The focus is on Ambrosia arte-misiifolia L. (Asteraceae), com-monly called Ragweed, which is a highly invasive plant with pol-len that causes allergic disease, increases allergenic sensitiza-

tion and has signifi cant negative impacts on health and quality of life. Since the development of allergies in Europe is currently undergoing rapid growth, there is an urgent need for aware-ness of invasive plants along with early detection and preven-tive management initiatives and sustainable strategies to control and reduce this invasive plant.

By gathering an interdisciplinary team of climate and air quality scientists, together with clini-cians and biologists, ATOPICA aims to quantify and project the eff ects of environmental changes on Ambrosia pollen-induced allergic disease in Europe, using a highly interdisci-plinary and integrated approach.

ContactsScientifi c CoordinatorDr. Michelle Epstein,MUW - Medizinische Universität Wien,Währinger Gürtel 18-20, A1090, Vienna, Austria

UNDERSTANDING & QUANTIFYING THE EFFECTS OF ENVIRONMENTAL CHANGES ON AMBROSIA ALLERGY

This research project has received funding from the European Union’s Seventh Framework Programme (FP7/2007-2013) under grant agreement n. 282687

atopica.eu

secretariat@atopica.eu

MUW Medizinische Universität Wien Wien, Austria ICTP

The Abdus Salam International Centre forTheoretical PhysicsTrieste, Italy

CHS

Dječja Bolnica SrebrnjakZagreb, Croatia

INERIS

Institut National de l’Environnement Industriel et des RisquesVerneuil-en-Halatte, France

CNRS

Centre National de la Recherche Scientifi queParis, France

Moverim ConsultingBruxelles, Belgium

PromoscienceTrieste, Italy

RRes

Rothamsted ResearchHarpenden, United Kingdom

UULM

Universität UlmUlm, Germany

UEA

University of East AngliaNorwich, United Kingdom

USR

Università Vita-Salute San Raff aeleMilano, Italy

pollen is in the air

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DISEASES

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GREENHOUSE GAS EMISSIONS / LAND-USE CHANGE / SOCIOECONOMIC POLICIES / GREENHOUSE GAS EMISSIONS / LAND-USE CHANGE / LAND-USE CHANGE / SOCIOECONOMIC POLICIES / GREENHOUSE GAS EMISSIONS / LAND-USE CHANGE / GREENHOUSE GAS EMISSIONS / SOCIOECONOMIC POLICIES / GREENHOUSE GAS EMISSIONS / LAND-USE CHANGE / SOCIOECONOMIC POLICIES / GREENHOUSE GAS EMISSIONS / GREENHOUSE GAS EMISSIONS / SOCIOECONOMIC POLICIES / LAND-USE CHANGE / SOCIOECONOMIC POLICIES / GREENHOUSE GAS EMISSIONS / LAND-USE CHANGE / SOCIOECONOMIC POLICIES/ GREEN HOUSE GAS EMISSIONS / LAND-USE CHANGE / POLLUTION / SOCIO POLICIES / GREENHOUSE GAS EMISSIONS / SOCIOECONOMIC POLICIES / LAND-USE CHANGE / GREENHOUSE GAS EMISSIONS / LAND-USE USAGEMIC POLICIES / GREENHO UUSE / SOCIOECONOMIC POLICIES / GAS / LAND-USE CHANGE / SOCIOECONOMIC / GREENHOUSE GAS EMISSIONS / LAND-USE CHANGE / AIR POLLUTION / LAND-USE CHANGE / GREEN SOCIOECONOMIC POLICIES / GREENHOUSE GAS EMISSIONS / LAND ALAND-USE CH / GREENHOUSE GAS EMISSIONS / AIR POLLUTIOC ONOMIC POLICIES / GREENHOUSE GAS EMISSIONS / AIR-USE/ GREENGASEMISSIONS / SOCIOECONOMIC POLICIES / GREENHOUSE GAS EMISSIONS / LAND -USE CHANGE / SOCIO ECONOMIC / AIR POLLUTION / GREENHOUSE GAS EMISSIONS / LAND-USE CHANGE / GREENHOUSE GAS EMISSIONS / SOCIOECONOMIC POLICIES / GREENHOUSE GAS EMISSIONS / LAND-USE CHANGE / SOCIOECONOMIC POLICIES / GREENHOUSE GAS EMISSIONS / GREENHOUSE GAS EMISSIONS / SOCIOECONOMIC POLICIES / LAND-USE CHANGE / SOCIOECONOMIC POLICIES / GREENHOUSE GAS EMISSIONS / LAND-USE CHANGE / SOCIOECONOMIC POLICIES / GREENHOUSE GAS EMISSIONS / LAND-USE CHANGE / SOCIOECONOMIC POLICIES / GREENHOUSE GAS EMISSIONS / SOCIOECONOMIC POLICIES / LAND-USE CHANGE / GREENH / SOCIOECONOMIC POLICIES / GREENHOUSE GAS EMISSIONS / LAND-USE CHANGE / SOCIOECONOMIC POL ICIES / LAND-USE CHANGE / EMISSIONS / LAND-USE CHANGE / GREENHOUSE GAS EMISSIONS / LAND-USE CHANGE / LAND-USE CHANGE / SOCIOECONOMIC POLICIES / GREENHOUSE GAS EMISSIONS / LAND-USE CHANGE / GREENHOUSE GAS EMISSIONS / SOCIOECONOMIC POLICIES / GREENHOUS / AIR POLLUTION / SOCIOECONOM / LAND-USE CHAN SOCIOECONOMIC POLICIES / LAND-USE / / LAND/ SOCIOECONOMIC POLICIES / LAND-USE / CHANGE / SOCIOECONOMIC POLICIES / GREENHOUSE GAS EMISSIONS / LAND-USE CHANGE / SOCIOECONOMIC POLICIES / GREENHOUSE GAS EMISSIONS / LAND-USE CHANGE / SOCIOECONOMIC POLICIES / GREENHOUSE GAS EMISSIONS / SOCIOECONOMIC POLICIES / LAND-USE CHANGE / GREENH / SOCIOECONOMIC POLICIES / GREENHOUSE GAS EMISSIONS / LAND-USE CHANGE / SOCIOECONOMIC POLICIES / GREENHOUSE GAS EMISSIONS / LAND-USE CHANGE / GREENHOUSE GAS EMISSIONS / LAND-USE CHANGE / LAND-USE CHANGE / SOCIOECONOMIC POLICIES / GREENHOUSE GAS EMISSIONS / LAND-USE CHANGE / GREENHOUSE GAS EMISSIONS / SOCIOECONOMIC POLICIES / GREENHOUSE GAS EMISSIONS / LAND-USE

DISEASES VECTORS / POLLEN POLLEN / AMBROSIA /

VECTORS / POLLEN / DISEASES VECTORS / POLLEN / AMBROSIA /

AMBROSIA / DISEASES VECTORS / POLLEN / POLLEES VECTORS / POLLEN / AMBROSIA /

DISEASES VECTORS / DISEASES DISEASES VECTORS / POLLEN / AMBROSIA / DISEASES VECTORS / POLLEN / AMBROSIA /

AMBROSIA / AMBROSIA / DISEASES VECTORS / POLLEN / PLANTS / DISEASES VECTORS / POLLEN / AMBROSIA / DISEASES VECTORS / POLLEN / AMBROSIA

DISEASES VECTORS / POLLEN / AMBROSIA / DISEASES VECTORS / POLLEN / INVASIVE PLANTS / AMBROSIA /

POLLEN / AMBROSIA / DISEASES VECTORS / POLLEN /

ASTHMA / ATOPIC DERMATITIS / VEORS / POLLEN / AMBROSIA /AMBROSIA / AMBROSIA / DISEASES VECTORS / DISEASES VECTORS /

AMBROSIARAGWEED

/ POLLEN / DISEASES VECTORS / POLLEN DISEASES VECTORS / POLLEN / AMBROSIA / POLLEN / AMBROSIA /

DISEASES VECTORS / POLLEN / AMBROSIAPOLLEES VECTORS / POLLEN / AMBROSIA / DISEES VECTORS / RAGWEED

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AMBROSIA /

DERMATITIS / ATOPIC DERMATITIS / ATOPIC DERMATITIS /

ATOPIC DERMATITIS / ASTHMA / HAY FEVERHAY FEVER / ATOPIC DERMATITIS /

GREENGASEMISSIONS / SOCIOECONOMIC POLICIES / GREENGASEMISSIONS / SOCIOECONOMIC POLICIES / GREENGASEMISSIONS /LAND -USE CHANGE / SOCIO ECONOMIC / AIR POLLUTION /

GREENHOUSE GAS EMISSIONS / LAND-USE CHANGE LAND-USE CHANGE SOCIOECONOMIC POLICIES / GREENHOUSE GAS EMISSIONS GREENHOUSE GAS EMISSIONS

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LAND-USE CHANGE / GREENH / SOCIOECONOMIC POLICIES / GREENHOUSE GAS EMISSIONS / LAND-USE CHANGE

ATOPIC DERMATITIS / ASTHMA / HAY FEVER / ATOPIC

HAY FEVER / ASTHMA / ATOPIC DERMATITIS /

ATOPIC DERMATITIS / ASTHMA / HAY FEVER / ATOPIC

DROUGHT / FLOOD / HEAT-WAVESHEAT-WAVESHEAT WAVES / DROUGHT / FLOOD / / DROUGHT / FLOOD /

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/ DROUGHT / FLOOD / HEAT-WAVES / DROUGHT / / DROUGHT / / DROUVES / HEAT-WA / HEAT-WAVES / DROUGHT / FLOOD / DROUGHT / FLOOD

HEAT-WAVES / DROUGHT /

anthropogenic factors, climate changes,

invasive allergenic plants:

the complex interplay across these multiple stressors might exacerbate the overall eff ect

of environmental change on pollen allergy

Our objectives are to

explore the pan-European impact of changes in climate, land use and air pollution on allergen

pollen-induced diseases through a chain of quantitative models

study vulnerable groups of patients and search for relevant indicators to assess the risk

establish statistical models of disease response to pollen concentrations for assessing future trends

examine the effects of environmental change, including exposure to air pollution on

pollen allergy in laboratory experiments

communicate with relevant stakeholders and provide recommendations useful to policy

makers dealing with air quality, public health, land use and climate change issues

Predicting future risk of pollen allergy in Europe

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