4806467 method for the detection of equine infectious anemia and other retrovirus infections using a...
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308 PATENT ABSTRACTS
4806355
M I C R O E N C A P S U L A T I O N O F L I V I N G T I S S U E A N D C E L L S
Mattheus F A Goosen, Geraldine M O'Shea, Anthony M Sun, Toronto, Canada assigned to Connaught Laboratories Limited
Living tissue or cells, for example, islets of Langerhans, are microencapsulated for im- plantation in the body for long term treatment of diabetes or other disease requiring organ trans- plantation. The microcapsules take the form of a biocompatible semi-permeable hydrogel mem- brane which permits the passage of materials and oxygen to the cells and metabolic products from the cells while retaining the cells encapsulated. The biocompatible semi-permeable membrane has an outer negatively-charged surface, which imparts to the microcapsules the ability to main- tain long term effectiveness.
480~67
M E T H O D F O R T H E D E T E C T I O N O F E Q U I N E I N F E C T I O U S
A N E M I A A N D O T H E R R E T R O V I R U S I N F E C T I O N S
U S I N G A C O M P E T I T I V E E N Z Y M E - L I N K E D
I M M U N O A B S O R B E N T A S S A Y A N D R E A G E N T S U S E F U L IN T H E
S A M E
James P Porter, Tatsuo Matsushita, Lyndal K Hesterberg assigned to Fermenta Animal Health Company
The present invention relates to a method of detecting either antibody or antigen in the serum of horses infected with equine infectious anemia using a competitive enzyme-linked immuno- absorbent assay technique and reagents useful in such an assay. The competitive enzyme-linked immunoabsorbent assay incorporates a purified virus antigen conjugate and a monoclonal anti- body specific for the virus antigen as both the reacting and competing components. Alterna- tively, the competitive enzyme-linked immuno- absorbent assay incorporates a purified virus antigen and a monoclonal antibody conjugate specific for the viral antigen as both reacting and competing components. This invention also relates to detecting antigen and antibody found in other retrovirus infections such as Acquired Immunodeficiency Syndrome in humans.