PATENT ABSTRACTS 249

A membrane batch-processor system and method for the fluid treatment of a plurality of specimen containing membranes, such as mem- branes having specimens of DNA, RNA, and protein molecules deposited thereon, includes a receptacle having an interior cavity and a plug- like closure slidably received in the cavity. A membrane stack is assembled from a plurality of membranes to be treated and flow definers inter- leaved between the membranes to defined a membrane stack of alternate flow definers and membranes. The flow definers are preferable fabricated from an open-weave fabric-like material to define multiple fluid pathways across the opposite surfaces of each membrane. Fluid distribution plenums are defined between to the receptacle and closure so that treatment fluid in- troduced into an entry plenum will flow through the multiple fluid pathways across the opposite surfaces of each membrane to expose each mem- brane to the treatment fluid and effect time and fluid efficient treatment of the membranes.

4795744

M O D U L A T I O N O F A I D S V I R U S - R E L A T E D E V E N T S BY D O U B L E -

S T R A N D E D R N A S

William A Carter assigned to HEM Research Inc

The use of mismatched dsRNA, e.g. Ampligen for the manufacture of compositions for use in the selective activation of a latent natural defense system within human cells, both cells already in- fected with AIDS virus as well as cells at risk to infection. Specific treatments for various clinical phases of the biological continuous of AIDS virus-related events ranging from subtle, early immunological lesions to advanced disease are described. Prophylaxis or prevention of AIDS virus related events, such as by introduction of mismatched double-stranded RNA into various blood products or biological fluids to be used in man (e.g., blood transfusion) or around man (e.g., dialysis programs) are also described.

4795699

T7 D N A P O L Y M E R A S E

Stanle Tabor, Charles Richardson assigned to President and Fellows of Harvard College

4795805

D E R I V A T I V E O F A D U L T T C E L L L E U K E M I A V I R U S A N T I G E N

P E P T I D E

This invention relates to T7-type DNA poly- merases and method for using them.

Seiga Itoh, Susum Sekine, Tadatsug Taniguchi, Mitsuaki Yoshida, Haruo Sugano, Sagamihara, Japan assigned to Kyowa Hakko Kogyo Co Ltd; Juridical Foundation Japanese Foundation for Cancer Researc

4795706

N O V E L E X P R E S S I O N C O N T R O L S E Q U E N C E S

Hansen M Hsiung, Dennis P Smith assigned to Eli Lilly and Company

The present invention comprises novel expres- sion control sequences that promote transcrip- tion of DNA. The novel sequences have been positioned for expression of structural genes encoding bovine growth hormone derivatives on recombinant DNA expression vectors. The novel expression control sequences function in both Gram-positive and Gram-negative or- ganisms and can be constructed by either DNA synthesizing instruments or by conventional modified phosphotriester methodology.

Recombinant plasmids are constructed by in- serting a DNA fragment coding for a fused pro- tein of an adult T cell leukemia virus antigen peptide and an enzyme into a vector DNA. Microorganisms are transformed with the recombinant plasmid and thereafter cultured to express the fused protein. The fused protein is useful for the detection and diagnosis of adult T cell leukemia.

4795855

T R A N S F O R M A T I O N A N D F O R E I G N G E N E E X P R E S S I O N

W I T H W O O D Y S P E C I E S

Joanne Fillatti, Luca Comai