APC

CD4 T lymphocytes

Monocytes

Epitheloid Macrophages

Tuberculosis Pathogenesis• Bacterial entry

• T Lymphocytes.

• Macrophages.

• Epitheloid cells.

• Proliferation.

• Central Necrosis.

• Giant cell formation.

• Fibrosis.

Mechanisms of granuloma formation

Infection - Immunity

Pathogenesis of TB:

• MBBS ST CCLL:

Mycobacterium Tuberculosis

Brucellosis

Berryliosis

Syphilis

Sarcoidosis

Cat-scratch disease

Crohn's disease

Leprosy

Lipid granuloma- Foreign body granulomas

Lymphogranuloma Inguinale

TB- Lymph node

Intestinal Tuberculosis

Lung Miliary Tuberculosis

Tubercular Caseous Necrosis & Giant cells

Tubercular Granulomatous Inflammation

Epitheloid Macrophages

Foreign body granuloma.

Lipid granulomas.

Sarcoidosis.

Crohns disease.

Fungal infections.

Cat scratch disease.

Brucellosis.

Leprosy.

Syphilis.

Berilliosis

Lymphogranuloma venerium