Holarrhena antidysentericaHolarrhena antidysentericaApocynaceae

Collection

• Obtained from wild sources

• Collected from plants of 8-12 yrs old

• Longitudinal & transverse incisions are made in the trunk from July – Sept

Description

• Shape recurved

• Surface buff / brownish colour

shows deep cracks

longitudinally wrinkled

• Odourless

• Taste bitter

• Fracture short , granular , splintery

Microscopy • Cork tangentially & radially elongated • Cork cambium present in several layers• Cortex stone cellsstone cells single/groups horizontal layers

Phloem fibersPhloem fibers absent

ParenchymaParenchyma encircle stone cells & also contain starch

• Medullary rays multiseriate

Widen towards outer side

In between them stone cells & calcium oxalate present

Constituents

• Steroidal alkaloids

Conessine

Norconessine

Isoconessine

Kurchine

Uses Uses • Antiprotozoal in the treatment of amoebic

dysentery