33f skin patches 3. 2 1 mccune albright 13m bone age - esrd 2

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33F Skin patches 3 Slide 2 2 Slide 3 1 Slide 4 McCune Albright Slide 5 13M Bone Age - ESRD 2 Slide 6 1 year later 1 Slide 7 Healing rickets distal ulna Slide 8 25M 1 Slide 9 Osteopoikilosis Benign sclerosing bone dysplasia Melorrheostosis Osteopathiastriata Slide 10 35M Chronic illness 6 Slide 11 5 Slide 12 4 Slide 13 3 Slide 14 2 Slide 15 1 Slide 16 ROD Slide 17 66F 3 Slide 18 2 Slide 19 1 Slide 20 Fibrous Dysplasia Slide 21 43F Slide 22 Slide 23 RTA-ROD Slide 24 29M Slide 25 Slide 26 Slide 27 POFD Slide 28 53M Slide 29 Slide 30 Slide 31 Slide 32 Renal Tx ROD - AVN Slide 33 57F Bone pain 8 Slide 34 7 Slide 35 6 Slide 36 5 Slide 37 4 Slide 38 3 Slide 39 2 Slide 40 1 Slide 41 Gauchers Slide 42 49M Bone pain Slide 43 Slide 44 Poly osstotic fibrous dysplasia Slide 45 25F Slide 46 4 Slide 47 3 Slide 48 2 Slide 49 1 Slide 50 Primary oxalosis secondary hyperparathyroidism Primary Hereditary hyperoxaluria AR, enzyme deficiency - carboligase Diffuse calcium oxalate deposits Secondary Disturbance of bile acid metabolism Usually diseases of terminal ileum 25F Slide 51 Acroosteolysis Tuft CVD, Psoriatic, Neuropathic, Thermal, Trauma, HPT, Porphyria, Epidermolysis bullosa, Phenytoin toxicity, Subungal exostosis, Snake venom Middle HPT, Hajdu Cheney, PVC Periarticular Psoriatic, Erosive OA, HPT, Thermal injury, Scleroderma, Multicetric reticulohistiocytosis Slide 52 20F 1 Slide 53 Familial osteolysis 20F Slide 54 7M Kyphosis Slide 55 Mucolipidosis 3 - PseudoHurlers Slide 56 Newborn Slide 57 Slide 58 Slide 59 3mM Short Slide 60 Slide 61 32M Stiffness and decreased ROM since child Slide 62 Slide 63 Trevors disease Dysplasia epiphysialis hemimelica 32M Stiffness and decreased ROM since child Slide 64 29F Short stature 8 Slide 65 7 Slide 66 6 Slide 67 5 Slide 68 4 Slide 69 3 Slide 70 2 Slide 71 1 Slide 72 Diastrophic dwarf 29F Short stature Slide 73 57M L hip pain 2 Slide 74 Sandwich vertebrae - Osteopetrosis 57M L hip pain 1 Slide 75 Osteopetrosis Marble bone, Defective osteoclasts AR, Infantile, Systemic, Leukaemia AD, Adult, Fxs, anaemia, CN palsy Sclerotic, peri and endosteal Erlenmyer flask Bone in bone, sandwich vertebrae Calvaria and mandible spared 57M L hip pain Slide 76 67F Lump 2 Slide 77 1 Slide 78 Fibrous Dysplasia Common Hamartomatous fibro-osseous metaplasia 70% monoostotic Polyostotic tends to be unilateral Usually expansile Shepherds crook, ground glass Any bone, but spine unusual 67F Lump Slide 79 Variable patients Same condition 6 Slide 80 5 Slide 81 4 Slide 82 3 Slide 83 2 Slide 84 1 Slide 85 Pseudohypoparathyroidism X-linked, renal and skeletal resistance to PTH Short, retarded, Decreased Ca, normal/increased PTH Brachydactyly 1,4,5 MC Ca basal ganglia, skin, SubQ Variable patients Same condition Slide 86 Same condition Various patients 8 Slide 87 7 Slide 88 6 Slide 89 5 Slide 90 4 Slide 91 3 Slide 92 2 Slide 93 1 Slide 94 Dermatomyositis Damaged chondroitin sulfate Atrophy, oedema, necrosis of muscle 30-60, F>M Calcification extremities and girdles Pointing of tufts Ass. Malignancy, lung, kidney, ovary, breast Same condition Various patients Slide 95 37F acute torticollis, stiffness and shortness of breath Slide 96 * Fibrodysplasia ossificans progressiva Slide 97 MOP / Stone man Rare, AD, sporadic Presents in childhood Stiffness, Heterotopic ossification Malformed fingers and toes Bone morphogenic protein (BMP) signaling pathway problem Fibrodysplasia ossificans progressiva Slide 98 Variable ages increasing stiffness Slide 99 * Fibrodysplasia ossificans progressiva Slide 100 MOP / Stone man Rare, AD, sporadic Presents in childhood Stiffness, Heterotopic ossification Malformed fingers and toes Bone morphogenic protein (BMP) signaling pathway problem Fibrodysplasia ossificans progressiva Slide 101 48M joint pains and dark pigmentation on ears Slide 102 Alkaptonuria * Alkaptonuria / Ochronosis Slide 103 Absence of homogentisic acid oxidase Pigmentation Arthropathy Osteoporotic with dense disc calcification Larger joints show DJD Slide 104 6mM Calcareous nodules Slide 105 Idiopathic calcinosis universalis * Idiopathic calcinosis universalis Slide 106 Rare, unknown cause Infants - subcutaneous Children - spreads to muscles Calcium phosphate and carbonate Serum calcium and phosphorous normal DDx - DMS, HPT, Calcium gluconate Slide 107 50F Life long problems Slide 108 * OGI Slide 109 Slide 110 45M ITC Slide 111 Slide 112 Slide 113 23M Hemophilia Slide 114 23M Slide 115 Slide 116 Mastocytosis Slide 117 65 Mastocytosis Slide 118 65 Mastocytosis Slide 119 65 Mastocytosis Slide 120 65 Mastocytosis Slide 121 65 Mastocytosis Slide 122 65 Mastocytosis Histamine release causes lucency, bodies reaction causes sclerosis. Mastocytosis Slide 123 Slide 124 Cherub - Fibrous Dysplasia Slide 125 Slide 126 16mF Dysostosis multiplex Slide 127 Slide 128 4M Morquios Slide 129 Slide 130 24F NF1 Slide 131 Slide 132 22F Calcinosis Interstitialis Universalis Dermatomyositis Slide 133 McCune Albright Slide 134 9F McCune Albright Slide 135 Polyostotic fibrous dysplasia Slide 136 24M Polyostotic fibrous dysplasia Slide 137 Slide 138 28BF mass in shoulder Slide 139 Idiopathic Tumoral Calcinosis * Slide 140 Periarticular calcified masses Shoulder, hip, elbow B>W, M=F Recur if resected Elevated phosphate, normal calcium Renal tubular phosphate resorption Slide 141 63F ITC Slide 142 Slide 143 Rib osteochondroma Slide 144 Slide 145 Slide 146 Massive osteolysis Slide 147 Slide 148 Slide 149 Multiple hereditary exostoses Slide 150 Slide 151 Multiple hereditary exostosis Slide 152 Multiple hereditary exostoses 21mF Slide 153 Multiple hereditary exostoses 21mF Slide 154 Multiple hereditary exostoses Slide 155 Newborn FLK Slide 156 OGI Slide 157 Slide 158 Camurati Engelman Slide 159 Slide 160 Slide 161 Metaphyseal dysplasia Slide 162 Slide 163