29th Annual Conference

Clinical Hematology & OncologyOmni Hotel • San Diego, California

Saturday, February 14 - Tuesday, February 17, 2009

AccreditationScripps Clinic is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical educa-tion for physicians.

Scripps Clinic designates this educational activ-ity for a maximum number of 27 AMA PRA Category 1 Credit(s)™. Physicians should only claim credit commensurate with the extent of the participation in the activity.

Saturday 7.5 credits (includes workshops)Sunday 7.5 credits (includes workshops)Monday 7.5 credits (includes evening symposium)Tuesday 4.5

Documentation of awarded credit is provided for registered attendees in exchange for completed activity evaluation. Certificates of attendance are available, upon request, at the end of the course.

Educational ObjectivesAfter participating in this course, the attendee should be able to:

• Describethepathogenesis,diagnosticapproachesandtherapeutic modalitiesavailableforhematologicdisordersdiscussed;

• Summarizethechangingapproachestohematologicmalignancies includinginnovationsindiagnosisandtreatment;

• Recognizeandlistnewtherapeuticoptionsforthetreatment ofanumberofcommoncancers;

• Evaluatetheevolvingapproachestobreastcancer;and

• Applypracticalexperienceintheclinicalsituationsdiscussed intheworkshopsessions.

Dear Colleague,Scripps Cancer Center’s 29th Annual Conference: Clinical Hematology and Oncology 2009 is designed for

hematologists, oncologists, surgeons, radiation oncologists, internists,

and others desiring an update in these specialty areas. The program

focuses on selected hematologic subjects the first day, hematologic

malignancies the second day, new developments in oncology with a

focus on issues of current interest the third day and breast cancer the

final day. This year, we are also pleased to offer a dinner symposium

discussing prostate cancer. Afternoon workshop sessions will be offered

focusing on topics in hematology and coagulation. All presenters will

discuss their approaches to challenging but common clinical situations

and there will be ample time for participant interaction.

The primary objective of this course is to bring together clinicians and

leading experts in diverse areas of hematology and oncology, affording

them an intimate environment in which to discuss new clinical develop-

ments and significant advances.

Course Information

DisclosureIt is the policy of Scripps Clinic to ensure balance, independence, objectivity, and scientific rigor in all sponsored educational programs. Course Directors, planning committees, faculty and all others who are in a position to control the con-tent of any educational activity sponsored by Scripps Clinic are required to disclose any real or apparent conflicts of interest related to the sub-ject matter of the educational activity.

Educational GrantsThis course is supported, in part, by educational grants from industry, in accordance with ACCME Standards. At the time of printing, a complete listing of commercial supporters was not avail-able. Appropriate acknowledgement will be given to all supporters at the time of the educational activity.

Cultural and Linguistic CompetencyThis activity is in compliance with California Assembly Bill 1195 which requires that all CME activities comprising a patient care element include curriculum addressing the topic of cultural and linguistic competency. The intent of this bill is to ensure that health care professionals are able to meet the cultural and linguistic concerns of a diverse patient population through effective and appropriate professional development. Cultural and linguistic competency was incorporated into the planning of this activity.

We are honored to have two lectureships showcased at the meet-

ing this year. Dr. Ron Natale will present the Dr. Robert Memorial

Longmire Lecture. Dr. Longmire was a valued member of Scripps

Clinic and this lectureship has been established in his memory. The

honoree of the prestigious 29th Annual Bernard L. Schwartz Lecture

will be Dr. Clifford Hudis. Dr. Hudis will be speaking on Triple Negative

Breast Cancer.

A glance at the agenda will reveal we have been most fortunate to

assemble an outstanding faculty for this meeting. We look forward to

seeing many past participants again in 2009 and invite to San Diego

those of you who have not previously had the opportunity to attend

this excellent conference.

Michael P. Kosty, M.D., F.A.C.P.Course Director

FacultyCourse Director

Michael P. Kosty, M.D., F.A.C.P.Medical Director, Scripps Green Cancer CenterDirector, Graduate Medical EducationScripps Clinic/Scripps Green HospitalLa Jolla, California

Scripps Faculty

Jeffrey Andrey, M.D.Division of Hematology & OncologyBlood and Marrow TransplantationScripps ClinicLa Jolla, California

Joan Kroener, M.D.Director, Breast ProgramScripps ClinicLa Jolla, California

James Mason, M.D.Director, Scripps Clinical Research and Continuing Medical EducationDirector, Scripps Blood and Marrow Transplant ProgramScripps ClinicLa Jolla, California

William Miller, M.D.Associate ProfessorDepartment of Molecular & Experimental MedicineThe Scripps Research InstituteLa Jolla, California

Alan Saven, M.D.Head, Division of Hematology & OncologyScripps ClinicLa Jolla, California

Darren Sigal, M.D.Division of Hematology & OncologyScripps ClinicLa Jolla, California

James Sinclair, M.D.Medical Director, Stevens DivisionScripps Cancer CenterLa Jolla, California

William Stanton, M.D.Medical Director,Scripps Cancer Center Mercy HospitalSan Diego, California

Guest Faculty

Paul Chapman, M.D.Member and Attending Physician Melanoma / Sarcoma Service Memorial Sloan-Kettering Cancer Center New York, New York

E. David Crawford, M.D.Professor of Surgery, Urology, and Radiation OncologyHead, Urologic OncologyUniversity of Colorado DenverAurora, Colorado

Angela DeMichele, M.D., M.S.C.E.Assistant Professor, Medicine and EpidemiologyCo-leader, Breast Cancer Program, Abramson Cancer CenterSenior Scholar, Center for Clinical Epidemiology and BiostatisticsUniversity of PennsylvaniaPhiladelphia, Pennsylvania

Terry Gernsheimer, M.D.Associate ProfessorUniversity of Washington School of MedicineDivision of HematologyPudget Sound Blood CenterSeattle, Washington

Morie Gertz, M.D.Chair, Department of MedicineMayo ClinicRochester, Minnesota

John Godwin, M.D., M.S.Professor of MedicineChief, Division of Hematology/Oncology and Associate DirectorSimmons Cooper Cancer InstituteSouthern Illinois University School of MedicineSpringfield, Illinois

Daniel Haller, M.D.Professor of MedicineUniversity of Pennsylvania Abramson Cancer CenterPhiladelphia, Pennsylvania

Sandra Horning, M.D.Professor of MedicineOncology andBlood and Marrow TransplantationStanford University Medical CenterStanford, California

Clifford Hudis, M.D.Chief, Breast Cancer Medicine ServiceMemorial Sloan-Kettering Cancer CenterNew York, New York

Hagop Kantarjian, M.D.Chairman and ProfessorLeukemia DepartmentM.D. Anderson Cancer CenterHouston, Texas

Neil Kay, M.D.Profesor of MedicineMayo ClinicRochester, Minnesota

Krystyna Kiel, M.D.Associate Professor Northwestern University School of MedicineSavannah, Georgia

John Kelton, M.D.Professor, Pathology and Molecular MedicineDean and Vice-PresidentFaculty of Health SciencesMcMaster UniversityHamilton, Ontario

Ann Mohrbacher, M.D.Associate Professor of Clinical Keck School of MedicineUniversity of Southern CaliforniaLos Angeles, California

Stephan Moll, M.D.Associate ProfessorDepartment of MedicineDivision of Hematology-OncologyUniversity of North Carolina School of MedicineChapel Hill, North Carolina

Barbara Murphy, M.D.Director, Pain & Symptom Management ClinicLeader, Head & Neck Research TeamVanderbilt Ingram Cancer CenterNashville, Tennessee

Ron Natale, M.D.Attending PhysicianDirector, National Lung Cancer Research Program Cedars-Sinai Medical CenterLos Angeles, California

Ruth O'Regan, M.D.Assistant ProfessorDirector, Translational Breast Cancer Research The Emory Clinic Atlanta, Georgia

Kornelia Polyak, M.D., Ph.D.Associate Professor of MedicineDana-Farber Cancer InstituteBoston, Massachusetts

Derek Raghavan, M.D., Ph.D.Director, Cleveland Clinic Taussig Cancer InstituteCleveland, Ohio

Christy Russell, M.D.Associate Professor of MedicineUniversity of Southern CaliforniaLos Angeles, California

Oliver Sartor, M.D.Piltz Endowed Professor of Cancer ResearchDepartments of Medicine and UrologyTulane Medical SchoolNew Orleans, Louisiana

Neil Shah, M.D., Ph.D.Assistant Professor, Division of Hematology/OncologyThe UCSF Helen Diller Family Comprehensive Cancer Center San Francisco, California

Susan Slovin M.D., Ph.D.Associate Attending Physician, Genitourinary Oncology ServiceMemorial Sloan-Kettering Cancer CenterAssociate Professor of Medicine, Department of MedicineWeill Medical College of Cornell UniversityNew York, New York

Wendy Stock, M.D.Professor of MedicineUniversity of ChicagoChicago, Illinois

Alexis A. Thompson, M.D., M.P.H.Director of Hematology ServicesAssociate Professor of PediatricsNorthwestern University's Feinberg School of MedicineChicago, Illinois

Program

Saturday & Sunday WorkshopsA Clinical Problems in Hematology I: Case-based Clinical Discussions John Kelton, M.D.B Clinical Problems in Hematology II: Case-based Discussions Focusing on Platelet Abnormalities Terry Gernsheimer, M.D.C Clinical Problems in Hematology III: Case-based Discussions Focusing on Anemias Morie Gertz, M.D.D Clinical Problems in Coagulation I: Case-based Discussions Focusing on Bleeding Stephan Moll, M.D.E Clinical Problems in Coagulation II: Case-based Discussions Focusing on Clotting John Godwin, M.D.

Sunday, February 15Malignant HematologyModerator James Mason, M.D.

7:00a.m. Continental Breakfast & View Exhibits

8:00a.m. Practical Strategies for the Application of Novel Agents in the Frontline Treatment of Multiple Myeloma Ann Mohrbacher, M.D.

8:45a.m. Treatment Options for the Patient with Amyloidosis Morie Gertz, M.D.

9:30a.m. Break & View Exhibits

10:00a.m. Nodular Lymphocyte-Predominant Hodgkin Disease Sandra Horning, M.D.

10:45a.m. Approach to the Patient with Imatinib-Refractory CML Neil Shah, M.D.

11:30a.m. New Options for a Patient with MDS Hagop Kantarjian, M.D.

12:15p.m. LunchModerator Alan Saven, M.D.

1:15p.m. New Options for a Patient with Mantle Cell Lymphoma Sandra Horning, M.D.

2:00p.m. Comprehensive Management of the CLL Patient Neil Kay, M.D.

2:45p.m. Controversies in the Treatment of AML: A Case-based Discussion Wendy Stock, M.D.

3:30p.m. Break & View Exhibits

4:00p.m. Workshops

5:30p.m. Adjourn

Friday, February 134:00to Pre-Registration & Welcome Refreshments6:00pm Course attendees, faculty & guests are invited to attend.

Saturday, February 14Nonmalignant HematologyModerator William Stanton, M.D. 7:00a.m. Registration, Continental Breakfast & View Exhibits

7:50a.m. Welcome & Introduction Michael Kosty, M.D.

8:00a.m. New Developments in Diagnosing and Treating ITP John Kelton, M.D.

8:45a.m. Therapeutic Options for the Patient with Non-Immune Thrombocytopenia Terry Gernsheimer, M.D.

9:30a.m. Break & View Exhibits

10:00a.m. Hematologic Aspects of Pregnancy Stephan Moll, M.D.

10:45a.m. Hemoglobin E Syndromes Alexis Thompson, M.D.

11:30a.m. Potpourri: Patient-based Clinical Problems John Kelton, M.D.

12:15p.m. LunchModerator Jeffrey Andrey, M.D.

1:15p.m. The Bleeding Patient Who Clots Stephan Moll, M.D.

2:00p.m. Thrombophilia: Common Questions on Laboratory Assessment & Management John Godwin, M.D.

2:45p.m. What is a Cryoglobulin and Why Should I Care? Morie Gertz, M.D.

3:30p.m. Break & View Exhibits

4:00p.m. Workshops

5:30p.m. Get Acquainted Reception Omni Hotel Course attendees, faculty and guests are invited to attend.

Monday, February 16State of the Art: Therapy of Cancer Moderator William Miller, M.D.

7:00a.m. Continental Breakfast & View Exhibits

8:30a.m. The Biology of Melanoma & Current Therapeutic Options Paul Chapman, M.D.

9:15a.m. Approaches to the Patient with Advanced Bladder Cancer Derek Raghavan, M.D.

10:00a.m. Break & View Exhibits

10:30a.m. Strategies for the Patient with Recurrent Colon Cancer: Individualizing Therapy Daniel Haller, M.D.

11:15a.m. LONGMIRE LECTURESHIP: A Rational Approach to the Patient with Advanced Lung Cancer Ron Natale, M.D.

12:00p.m. Lunch

State of the Art: Supportive OncologyModerator Darren Sigal, M.D.

1:00p.m. Improving Cancer Pain Management Barbara Murphy, M.D.

1:45p.m. Cognitive Impairment in Cancer Patients TBD

2:30p.m. Integrating Supportive and Palliative Care into Oncologic Patient Care TBD

3:15p.m. Break

Dinner Symposium: Prostate CancerModerator Michael Kosty, M.D.

3:45p.m. Preventing Prostate Cancer: Update 2009 E. David Crawford, M.D.

4:30p.m. Do We Over Treat Prostate Cancer? Oliver Sartor, M.D.

5:15p.m. 2009 Options for the Hormone-Refractory Patient Susan Slovin, M.D.

6:00p.m. Dinner: TheUltimateSkyboxatDiamondViewTower The Ultimate Skybox is located just a few short blocks from the Omni Hotel on the top floor of Diamond View Tower, which sits just outside the right-field fence of Petco Park. The Ultimate Skybox has breath taking views of the San Diego skyline, San Diego Bay, Coronado Island and looks directly into Petco Park.

You and one guest are welcome to attend, please be sure to RSVP for this event on the registration form! You will receive tickets to attend this dinner once you check-in with the Scripps Registration Desk at the conference.

Tuesday, February 17Focus on Breast CancerModerator Joan Kroener, M.D.

7:00a.m. Continental Breakfast

8:00a.m. Risk Prediction for Breast Cancer Ruth O’Regan, M.D.

8:45a.m. Breast Cancer Stem Cells: Fact or Fiction? Kornelia Polyak, M.D.

9:30a.m. SCHWARTZ LECTURESHIP: Triple Negative Breast Cancer Clifford Hudis, M.D.

10:15a.m. Break

10:30a.m. Why Can’t We Cure Metastatic Breast Cancer? Angela DeMichele, M.D. 11:15a.m. Targeted Options for the Patient with Breast Cancer Christy Russell, M.D.

12:00p.m. Radiotherapy of Breast Cancer: Is Less More? Krystyna Keil, M.D.

12:45p.m. Final Adjournment

Program

Conference Location & Hotel InformationOMNI SAN DIEGO HOTEL The Omni San Diego Hotel, a 32-story luxury hotel, opened in the spring of 2004 and is connected via skybridge to PETCO Park, the San Diego Padres Ballpark. Nestled in the heart of the historic Gaslamp Quarter, the hotel is just moments away from the city’s top sites and attractions - including beaches, parks, museums and theaters. Take in the extraordinary views of the San Diego Bay, the downtown skyline or ballpark from the comforts of your guest room, or enjoy the sun-soaked outdoor terrace which features a pool, spa and fireplace.

TransportationThe Omni San Diego Hotel is a short 4 miles (10 minute cab ride) from the San Diego International Airport. San Diego offers many options for transportation including the San Diego Trolley, easy accessible cabs or stop by the Concierge desk to have them arrange transportation for you.

DiningWhether you’re searching for a light breakfast, an elegant dinner, or a cozy meal in your room, you can find just the right menu option at the Omni. Restaurants located on property are McCormick & Schmick’s Seafood Restaurant, Morsel’s, and the Terrace Bar & Grill. Guest room dining is also available 24-hours and all items are pre-pared by the culinary team of McCormick & Schmick’s.

Local AreaThe Omni is just steps away from the historic Gaslamp Quarter, one of San Diego’s most historic areas with century-old Victorian buildings, eclectic restaurants, shops, art galleries, and night clubs. Horton Plaza, a seven-block mall, just a short walk from the Omni, features a wide-variety of shops and restaurants. Seaport Village, a seaside village featuring one-of-a-kind shops, restaurants and side-walk eateries is located on the water just one half-mile away. Two miles from the hotel is Balboa Park, the cultural center of the city, featuring 12 distinctive museums, beautiful gardens, and the World Famous San Diego Zoo.

AccommodationsRelax in the privacy of San Diego's finest hotel accommodations. The Omni San Diego Hotel features over 500 elegant guest rooms and suites which are decorated in a luxurious, contemporary style and fea-ture the most modern amenities. The accommodations will welcome you with California warmth and sophistication throughout your stay.

Hotel Amenities• Complimentary Hi-Speed Wireless & Wired Internet Access

• Complimentary Fitness Center

• Get Fit Kits & Get Fit Guestrooms

• Outdoor heated pool & spa

• DVD player in each room

• Spa Treatment Room

• Full Service Concierge

• Omni Kids Program

• Express Check-in & Check-out

Rates & ReservationsPlease make your own hotel reservations. Make sure to mention the Scripps conference when requesting the especially low rate of $235 per night (excludes tax). Make your reservations early! A block of rooms will be held for Scripps until January 22, 2009. After this time, reservations will be accepted on a space and rate available basis only.

Omni San Diego Hotel675 L Street San Diego, CA 92101

Reservations: (619) 231-6664

Fax: (619) 231-8060

Web: www.omnisandiegohotel.com

(enter the group code 17300101639 for online reservations)

Discounted Scripps Rate: $235/night

Full Conference:................ $600 Physicians

................ $350 Fellows/Residents/Others

Day Rate:

................ $250 Physicians Sat Sun Mon Tue (circle one)

................ $175 Fellows/Residents/Others Sat Sun Mon Tue (circle one)

Saturday & Sunday Workshops Circleyourfirstandsecondchoicesforworkshops.Workshopsarefilledonafirst-come,first-servebasis.

Saturday1st Choice:A B C D E 2nd Choice:A B C D E

Sunday 1st Choice:A B C D E 2nd Choice:A B C D E

Monday Dinner

................ Willbeattending

................ Willbeattendingwithoneguest

Conference Course MaterialsIf you are unable to attend the conference the course materials are available for purchase.

................ $150Printed Syllabus & CD-ROM which contains the final presentations/audio of program

Please print clearly. Your badge will read as follows:

DATE RECEIVED CHECK NO / APPROVAL CD AMOUNT CONFIRMATION SENT INIT IALS

.................................................................................................................................................................................................................................................................................................................................................................................................

Payment Method Check Please make checks payable to Scripps

.........Visa ........MasterCard ........Amex ........Discover If paying by credit card, please complete information below

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c r e d i t c a r d b i l l i n g a d d r e s s ( i f d i f f e r e n t f r o m a b o v e )

Refund, Substitution and Cancellation Policy The course tuition is refundable, minus a $100 processing fee, if your cancellation is received in writing no later than February 6, 2009. Attendee substitutions are allowed, but notification must be made in writing by February 6, 2009. After this date, under no circumstances will refunds, credits, or substitutions be granted. No refunds or credits will be given to “no shows.” Scripps reserves the right to cancel this conference, in which case a full refund of your registra-tion fee will be provided. We are unable to refund any travel costs (flight, hotel, etc.) in the case of Scripps cancellation.

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Office Use Only

To RegisterOnline www.scripps.org/conferenceservicesFax (858) 652-5565Phone (858) 652-5400Mail Scripps Conference Services & CME Hem/Onc Conference 11025 North Torrey Pines Road Suite 200, Maildrop: SCRC200 La Jolla, CA 92037

Questions? Contact Scripps Conference Services & CMEPhone (858) 652-5400Email med.edu@scrippshealth.org

Conference Registration Included:continental breakfasts, coffee breaks, lunches, receptions, the Monday Dinner Symposium, the course syllabus and CD-ROM.

1. Please indicate your primary institutional affiliation. PrivatePractice

Hospital/ClinicalFacility

Corporate(BiochemorPharmaceutical)

MedicalSchool

Other:....................................................................

2. Please indicate your primary job responsibility. DirectPatientCare

Research

Teaching

Administration

Other:....................................................................

3. Types of Cancers/Disorders you treat/research (checkallthatapply).

Cancer

BreastCancer

ColonandRectumCancer

HeadandNeckCancers

HematologicDisorders

Leukemia

LungCancer

Melanoma

MultipleMyeloma

Myelodysplasia

Hodgkin’s/Non-Hodgkin’sLymphoma

OvarianCancer

ProstateCancer

Other:....................................................................

f i r s t, m i , l a s t n a m e d e g r e e ( m . d . , d o , p h d , e t c )

h o s p i t a l / a f f i l i at i o n

s t r e e t a d d r e s s

c i t y s t at e / p r o v i n c e z i p c o d e

o f f i c e t e l e p h o n e f a x

e m a i l

s p e c i a l n e e d s , i n c l u d i n g d i e t a r y r e s t r i c t i o n s

Registration &Information

Recording and Photography Clause Scripps reserves exclusive rights to record (audio and video) and/or pho-tograph all conference proceedings for use in marketing materials, presentations and course content sales.

Onsite Registration Fee Clause Please note: pre-registra-tion will be accepted through February 10, 2009. After this date, registrations will only be accepted on-site and will incur an additional $25 fee.

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Clinical Hematology & Oncology 2009