28-day step 1 study schedule

7/29/2019 28-Day Step 1 Study Schedule

1/12Day1

GeneralO

verview

&BeginBiochemistry

Objective

Assignments

Source

Details

Est.

Time

Self

Assessment

Completesa

mpletestmaterials

fromNBME

NBMECD-ROMordownload

fromwww

.nbme.org

Complete15

0samplequestions,andnotetroubleareasto

focuson.

3hrs

Gen

eraloverviewof

materialtobecovered

ReadThroughSectionIntroductory

Materialfrom

FirstAid,andSkim

SectionII

FirstAid

Learnabout

thetest,andhowtobestuseFirst

Aidasa

resource.

4hrs

BasicMetabolism

Chapters5&6,andsample

questionsat

endofeachchapter.

Bookmarkfigure6.2andrefertoit

beforestudy

ingeachbiochemical

pathway.

Lippincott'sBiochemistry

UnderstandtheroleofATP.

Knowwherethee

lectron

transportcha

in,andoxidativephosphorylationoccurandhow

theyfitintotheoverallmetabolicscheme.

Reviewthemain

classesofce

llreceptorsandsignalingmechanisms.

2.5

hrs

Day

2

Continue

Biochemistry

Objective

Assignments

Source

Details

Est.

Time

Stru

cture&Metabolism

ofC

arbohydrates

Chapters11

,12,

13&questions


Reviewthed

igestionofsugarsanddisordersoffructose,

galactose,andlactosemetabolism.

Spendmoretimeon

glycogenme

tabolism,

itsregulation,andrelateddisorders.

UseFigure1

3.7

tomemorizetheglycogenstoragediseases.

3hrs

Glyc

olysis

Chapter7&

questions


Knowthesta

rtandendpoints,

hormonalregula

tion,energy

yield,andva

riousfatesofpyruvate.

1.5

hrs

Gluc

oneogenesis

Chapter8&

questions,

Review

Figure6.2again!


Studyitbycomparisontoglycolysis.

Knowthe

reactions&

regulationun

iquetogluconeogenesis.

1hr

CitricAcidCycle

Chapter9&

questions


Focusonsta

rtandendpoints,placeinoverallmetabolism,

andregulatio

n.

1hr

HexoseMonophosphate

Shunt

Chapter10&questions


SkimreactionsandfocusonG6PDdeficiency

1hr


2/12Day3

Continue

Biochemistry

Objective

Assignments

Source

Details

Est.

Time

LipidMetabolism

Chapter17&questions


Focusonrolesofpancreaticlipaseandbilesalts.

Fattyacid

metabolism:

knowwheresynthesisoccurs,rela

tionshipto

glucosemetabolism,androleoftriacylglycerols

forstorageof

fattyacids.Reviewmobilizationofandoxidatio

noffattyacids.

Finally,carefullyrevieweicosanoids,

focusingo

nfigure17.2

0

3hrs

Phospholipids&

Glyc

olipids

SkimChapters18,

19


Gainasenseofwhattheseare,

butdonotmem

orize

structuresor

pathways.

Focusonrelateddisordersinstead,

usingfigures

18.1

0,

19.4.

1hr

Cho

lesterol&Steroid

Metabolism

Chapter20,

Sect.I-VII


Reviewcholesterolsynthesis(esp.

theroleofH

MGCoA

reductase)a

nditsregulation.

Understandsynthesisandrole

ofbilesalts.

Reviewbiologyoflipoproteinsand

theirrolein

atherogenes

is.

Keyfiguresare20.1

2,

20.1

4,20.1

6.

2hrs

Ster

oidHormones

Chapter20,

Sect.VII


Knowthema

jorenzymedeficienciesinsteroid

synthesisand

knowwhere

steroidreceptorsactinthecell.Studyfigures

20.1

9,

20.20

.

1hr

Day4

Continue

Biochemistry

Objective

Assignments

Source

Details

Est.

Time

Protein&Enzymes

Chapters1-4&questions


Becomefam

iliarwithbasicpropertiesofamino

acids,

levelsof

proteinstructure,

hemoglobin,andcollagen.F

orenzymes,

focusonapp

reciating(notmemorizing)theMichaelis-Menten

equation,typ

esofenzymeinhibition,modesof

enzyme

regulation,andtheuseofenzymesinclinicaldiagnosis.

4hrs

Dige

stionofDietary

ProteinsandNitrogen

Metabolism

Chapter21&questions


Learntheva

riouspancreaticproteasesandhowtheyare

regulated.U

nderstandtransaminationandoxid

ative

deamination,

butdon'tmemorizepathways.

Sp

endmoretime

onureacycleandammoniametabolismfocusingonfigures

21.4,

21.1

1,

21.1

7.

2hrs


3/12MetabolismofAmino

Acid

CarbonSkeletons

Chapter22


Emphasizer

elevantdisorders.

Focusonfigure

s22.2,

22.1

6.

1hr

Day5

Continue

Biochemistry

Objective

Assignments

Source

Details

Est.

Time

Hem

e,

Porphyrins,

Serotonin,

Histamineand

Catecholamines

Chapter23


Focusonthe

porphyriasandbilirubinmetabolis

m.

Focuson

figures23.5

and23.7.

1hr

Glyc

osaminoglycansand

Glyc

oproteins

SkimChapters14,

15


Knowwhattheyareandknowtherelateddisorders.

Don'tget

tooboggedd

ownindetails-juststudyfigures14.1

2and15.4,

thenmoveon.

1hr

NutritionandVitamins

Chapters27

,28


Knowtheda

ilyenergyrequirementsandvitamindeficiences.

FocusonabsorptionofvitaminB12andperniciousanemia,as

wellasvitam

inD.

Focusonfigures28.1

2,and

28.1

8.

3hrs

NucleotideMetabolism

Chapter29


Understanddifferencesbetweendenovoands

alvagepurine

synthesis.S

tudypurinedegradationandthepathophysiology

ofgoutandA

DAdeficiency.

Studyfigures29.7

,29.9,

29.1

0.

2hrs

Day6

FinishBiochemistry

Objective

Assignments

Source

Details

Est.

Time

IntegrativeMetabolism

Chapters24

,25,

26


Synthesizetheinformationyou'vereviewedthis

weekby

studyinginsu

lin,glucagon,

thefed/starvedstate

s,andthe

metabolicas

pectsofdiabetesmellitus.

Timespentonthese

topicswillbe

VERYWORTHWHILE.

5hrs

Day7

GeneralP

harmacology

Objective

Assignments

Source

Details

Est.

Time

Pharmacokinetics&

Pharmacodynamics

Chapters1,2

Lippincott'sPharmacology

Studygeneralprinciplesofpharmacology.

Spe

cificagentswill

becoveredw

ithrelevantorgansystems.

2hrs

Auto

nomicDrugs

Chapters3-7


Knowdiffere

nttypesofadrenergicandcholinergicreceptors

cold.

Studyfigures3.3,

3.6,

4.2,

5.2,

6.1

5,

7.10

.

5hrs


4/12Day8

BeginMic

robiology

Objective

Assignments

Source

Details

Est.

Time

Bacteria

Chapters1-15

ClinicalM

icrobiologymade

Ridiculou

slySimple

Relyheavily

oncharts.Startbuildingbuzzword

associations

withcharacterisiticsofeachorganismandhow

isidentified

(withaspecialstain,culturemedium,etc.)

Also,

timespent

withQbankq

uestionsherewillbegolden.

10hrs

Day9

Continue

Microbiology

Objective

Assignments

Source

Details

Est.

Time

Antibiotics

Chapters28

-33


Thisishighyieldmaterial,read,reviewandcon

tinuetodo

Qbankquestionstokeepbuildingbuzzwordassociations.

6hrs

Fungi

Chapter20

ClinicalM

icrobiologymade

Ridiculou

slySimple


tinuetodo


1.5

hrs

Antifungals

Chapter34



tinuetodo


1hr

Day10

FinishMicrobiology

Objective

Assignments

Source

Details

Est.

Time

Viruses

Chapters22

-29

ClinicalM

icrobiologymade

Ridiculou

slySimple


tinuetodo


6hrs

Antivirals

Chapter37


Reviewantiv

iralagents,particularlymechanism

sofaction.

1hr

Parasites

Chapters30

,31

ClinicalM

icrobiologymade

Ridiculou

slySimple


tinuetodo


2hrs

Antiparasitics

Chapters35

,36


Reviewantip

rotozoalandantihelminthicagents

,particularly

multi-drugre

gimens

1hr

ClinicalVignettes

Undergro

undClinical

Vignettes

-Microbiology

Goodforgro

upstudy,andanotherwaytokeep

sharpening

buzzwordrecall.

3hrs


5/12Day11

Immunolo

gy&GeneralPathology

Objective

Assignments

Source

Details

Est.

Time

ReviewImmunology

PartVII

MedicalM

icrobiology&

Immunology:Examination

andBoar

dReview

Excellent,co

ncisesummaryofimmunology.

4hrs

CellularInjury

Chapter1

BRSPathology

Focusonme

chanismsofcellularinjuryanddifferences

betweennec

rosis&apoptosis

0.5

hr

Infla

mmation

Chapter2

BRSPathology

Distinguishm

echanismsandhistologiccharacteristicsofacute

vs.chronicin

flammation.

1hr

Hem

ostasis

Chapter3

BRSPathology

Knowcoagulationcascade,

typesofembolism,

andtypesof

shock.

1hr

Gen

eticDisorders

Chapter4

BRSPathology

0.5

hr

Imm

uneDysfunction

Chapter5

BRSPathology

Focusonimmunedeficiencydisorders,autoimmunity,and

collagenvas

culardisease

0.5

hr

Neo

plasia

Chapter6

BRSPathology

Distinguishb

etweentumorsuppressorgenes&

oncogenes,

knowmecha

nismsofcarcinogenesis,andthep

ropertiesof

malignantce

lls.

1hr

EnvironmentalPathologyChapter7

BRSPathology

Quicklyrevie

w

0.5

hr

NutritionalDisorders

Chapter8

BRSPathology

Reviewvitam

indeficienciestorefreshbiochem

memory.

0.5

hr

Day12

CellularB

iology

Objective

Assignments

Source

Details

Est.

Time

DNA

,RNA,

Proteins

Chapters30

-33


Knowmecha

nismsofDNArepair,

differenttype

s/rolesof

RNA,mecha

nismoftranslation,andmolecular

biology

techniques.

Focusonfigures30.2,

30.1

6,

30.1

9,

30.2

2,

31.1

1,

32.9.

3.5

hrs

Cell

Membranes

Chapter1

BRSCellBiology&Histology

Knowpropertiesofmembranesandmembrane

proteins.

1hr

Nucleus

Chapter2


Knowconten

tsofnuclei,andRNAimport/exportmechanisms.

0.5

hr


6/12Cyto

plasm

Chapter3


Revieworga

nellesandfunction

0.5

hr

ExtracellularMatrix

Chapter4


Knowdiffere

nttypesofcollagen,

basementmembrane

composition,andotherECMcomponents.

1hr

Epithelia&Connective

Tiss

ue

Chapters5,6


Reviewtypesofepitheliaandlocationsofeach.

Review

connectivetissuefocusingonbonehistology.

1.5

hrs

Day13

CellularP

hysiology&GeneralEmbryology

Objective

Assignments

Source

Details

Est.

Time

Cell

Physiology

Chapter1

BRSPhy

siology

Knowmecha

nismsofiontransport,actionpotentials.

1hr

Emb

ryology

Chapters1-4

BRSEmbryology

Knowstages

fromzygotethroughembryo.

Review3Germ

celllayersan

dtheirderivativetissues.

3hrs

Birth

Defects

Chapters17

,18

BRSEmbryology

1.5

hrs

Exam

DiagnosticT

est

BoardSimulatorSeries-

BodySys

temsReview

Goodopport

unitytoidentifyweaknessesinorgansystem

areas.

2hrs

Day14

Thorax

Objective

Assignments

Source

Details

Est.

Time

Emb

ryologyofthorax

Chapters5,

11

BRSEmbryology

Knowthecongenitalcardiacabnormalities,and

fetal

circulation.Alsounderstandthestagesoffetal

lung

maturation.

3.5

hrs

ThoracicAnatomy

Chapter2

(Alsouse

Netter'sAtla

sforreference)

HighYieldGrossAnatomy

3hrs

Histologyofthoracic

viscera

Chapters11

,15


Beabletodistinguisharteriesandveinsincros

ssection.

Understandarchitectureofthegasdiffusionbarrierinthe

lungs.

1hr


7/12Day15

CardiovascularSystem

Objective

Assignments

Source

Details

Est.

Time

Cardiovascular

Physiology

Chapter3

BRSPhy

siology

Reviewhemodynamics,electrophysiology,card

iaccycle,

bloodpressu

reregulation,responsestoexercis

e,volumeloss,

altitude.

Und

erstandpre-load,after-load,

Frank-Starlingcurve,

andconduction.

1.5

hrs

CardiacPathology

Chapter10

BRSPathology

Studythisch

apterthoroughly.

1.5

hrs

VascularPathology

Chapter9

BRSPathology

Studythisch

apterthoroughly.

1hr

Cardiovascular

Pharmacology

Chapters16

-19,

21


Knowdrugs

usedtotreatCHF,

HTN,arrhythmias,angina,and

hyperlipidem

ia.

5hrs

Day16

Respirato

rySystem&

BeginHematology

Objective

Assignments

Source

Details

Est.

Time

RespiratoryPhysiology

Chapter4

BRSPhy

siology

Knowthevariouslungvolumemeasurements,and

understanda

cid-basedisorders.

1.5

hrs

RespiratoryPathology

Chapter14

BRSPathology

Studythisch

apterthoroughly.

1.5

hrs

Respiratory

Pharmacology

Chapter22


0.5

hrs

ClinicalVignettes

Volume1:C

ases1-19,

Volume2:

Cases52-66

Undergro

undClinical

Vignettes

-Patho-physiology

Goodopport

unityforgroupreview.

2hrs

HistologyofBone

Marrow,

Spleen,

&

Lym

phNodes

Chapters10

,12(andahistologic

atlasforfurtherreview)


Familiarizey

ourselfwithlymphnodearchitecture,and

understandt

hespleen.

UnderstandRBC,

WBC

,platelet

lineages.

3hrs

Day17

FinishHe

matology

Objective

Assignments

Source

Details

Est.

Time

Anemia

Chapter11

BRSPathology

Knowpathop

hysiologyandlabdifferentiationofvarious

etiologiesof

anemias.

2hrs

Hem

patopoietic&

Lym

phoreticular

Neo

plasia

Chapter12

BRSPathology

Distinguishb

etweenleukemia&lymphoma.

Understand

differenttype

sofeach.

2hrs

Hem

orrhagicDisorders

Chapter13

BRSPathology

Knowhowto

diagnoseandcorrecteachdisorder.

1hr


8/12Drugsaffecting

coagulation

Chapter20


1.5

hrs

AnticancerDrugs

Chapter38


1.5

hrs

ClinicalVignettes

Volume1:C

ases74-102

Undergro

undClinical

Vignettes

-Patho-physiology

2hrs

Day18

Gastroint

estinalSystem

Objective

Assignments

Source

Details

Est.

Time

Emb

ryologyofGutand

BodyCavities

Chapters10

,16

BRSEmbryology

Understandrotationofgutandrelatedmalformations.

Know

whichstructu

resarederivedofforegut,midgut,

hindgut,in

additiontovascularsupplies.

1.5

hrs

AbdominalAnatomy

Chapter3(A

lsorefertoNetter's

atlas)


2hrs

HistologyofGITract

Chapter6


Knowlayers

ofgutwall.Understandliverstructure,portal

bloodflow,a

ndbileflow.

1.5

hrs

GIP

hysiology

Chapter6

BRSPhy

siology

Understandinnervationofgutandguthormone

s

1hr

Day19

Gastroint

estinalSystem

Objective

Assignments

Source

Details

Est.

Time

Gas

trointestinal

Path

ology

Chapter15

BRSPathology

Studythisch

apterthoroughly.

2hrs

Hep

atobiliaryand

ExocrinePancreatic

Path

ology

Chapter16

BRSPathology

Studythisch

apterthoroughly.

2hrs

GIP

harmacology

Chapter24


KnowGIdru

gsaswellasantiemetics.

2hrs

ClinicalVignettes

Volume1:C

ases40-73

Undergro

undClinical

Vignettes

-Patho-physiology

Goodopport


2hrs

Day20

GenitoUrinarySystem

Objective

Assignments

Source

Details

Est.

Time


9/12Emb

ryologyofGU

Organs

Chapters6,

13,

14

BRSEmbryology

3hrs

AnatomyofPelvisand

Perineum

Chapters4,

5


3hrs

HistologyofGUOrgans

Chapters18

,19,

20


Knowthema

turationsequenceofspermatocytesandovarian

follicles.

Knowtheanatomyofthenephron.

3hrs

Day21

GenitoUrinarySystem

Objective

Assignments

Source

Details

Est.

Time

Ren

alPhysiology

Chapter5

BRSPhy

siology

1.5

hrs

Diur

etics

Chapter23


1.5

hrs

Ren

al&UrinaryTract

Path

ology

Chapter17

BRSPathology

Studythisch

apterthoroughly.

1.5

hrs

MaleReproductive

Path

ology

Chapter18

BRSPathology

Knowthedifferenttypesoftesticularcancer,an

dthebiology

ofBPHandprostatecancer

1hr

Fem

aleReproductive

Path

ology

Chapter19

BRSPathology

Understandcervical,uterinecancer.

1.5

hrs

ClinicalVignettes

Volume2:C

ases30-51,and83-103Undergro

undClinical

Vignettes

-Patho-physiology

Goodopport


2hrs

Day22

EndocrineSystem

Objective

Assignments

Source

Details

Est.

Time

HistologyofEndocrine

System

Chapter13

BRSEmbryology

Reviewstruc

tureofendocrineorgans,anduse

anatlasfor

additionalpictures.

1hr

Physiology

Chapter7

BRSPhy

siology

Knowhormo

nalaxes

2.5

hrs

Insu

linandoral

hypoglycemics

Chapter26


Knowdiffere

nttypesofinsulinandtheirhalflives.

Know

classesofor

alhypoglycemicsandsideeffects.

1.5

hrs

Ster

oidHormones

Chapter27


1hr


10/12ClinicalVignettes

Volume1:C

ases25-38

Undergro

undClinical

Vignettes

-Patho-physiology

Goodopport


2hrs

EXA

M

BodySystem

sIII-

Test1


BodySys

temsReview

Toughquest

ions,

butgreatexplanations.

Well

worththetime

topushyourselfabitandsolidifythematerialyou'velearned.

1.5

hrs

Day23

NervousSystem

Objective

Assignments

Source

Details

Est.

Time

Emb

ryologyofHead,

Neck,

&NervousSystem

Chapters7,

8,

9,

10

BRSEmbryology

Knowbranch

ialarches/cleftsandtheirderivativ

es.

Understandthetransitionfromneuralplatetom

atureCNS.

Knowfateof

neuralcrestcells.

3hrs

Hea

d&NeckAnatomy

Chapter8(a

lsorefertoNetter)


2hrs

Neu

roanatomy

Chapters1-23

HighYieldNeuroanatomy

6hrs

Day24

NervousSystem

Objective

Assignments

Source

Details

Est.

Time

Neu

rophysiology

Chapter2

BRSPhy

siology

UnderstandSynaptictransmissionandaxonalconduction

2hrs

Neu

ropathology

Chapter23

BRSPathology

KnowtypesofCNSinfections,

tumors,andvas

culardisorders.

2hrs

ClinicalVignettes

Volume2:C

ases45-61,

Anatomy

Cases40-56.

Undergro

undClinical

Vignettes

-Patho-physiology

Goodopport


2hrs

Neu

ropharmacology

Chapters8,

10,

11,

14,

15


Reviewdrug

susedtotreatepilepsy,

Parkinson

's.

Alsoreview

anestheticsandanalgesics.

3.5

hrs

Day25

Musculos

keletalSystem

Objective

Assignments

Source

Details

Est.

Time

Emb

ryology

Chapter15

BRSEmbryology

1hr

AnatomyofLimbsand

Back

Chapters1,

6,

7(alsouseNetter)


3.5

hours

Histology

Chapters7,

8,

10


Reviewhisto

logyofskin,muscle,

bone,andcartilage

2hrs


11/12Anti-InflammatoryAgents

and

Autocoids

Chapters39

,40


2hrs


12/12

y26

Musculos

keletalSystem

jective

Assignments

Source

Details

Est.

Time

matologicPathology

Chapter21

BRSPathology

Focusonma

lignancies(melanoma,

SCC,

BCC

)andrefertoa

dermatology

atlassothatyoucandifferentiatebetweenthem.

1.5

hrs

culoskeletal

ology

Chapter22

BRSPathology

1.5

hrs

icalVignettes

Volume3:C

ases9-18,and96-104.

AlsoAnatom

y:Cases62-84

Undergro

undClinical

Vignettes

-Patho-physiology

Goodopport


2hrs

m

BodySystem

sII-Test1


BodySys

temsReview

Toughquest

ions,

butgreatexplanations.

Well

worththetime

topushyourselfabitandsolidifythematerialyou'velearned.

2hrs

y27

BehavioralSciences&Biostatistics

jective

Assignments

Source

Details

Est.

Time

icalVignettes

Allcases

Undergro

undClinical

Vignettes

-BehavioralSci.

3hrs

chotropicDrugs

Chapters9-12,

13


3hrs

tatistics

Readentire

book

HighYieldBiostatistics

Understandsensitivity,specificity,

PPV,

NPV.Bepreparedto

calculaterisk

,oddsratios,etc.

4hrs

y28

FinalRev

iew

&ExamL

ogistics

jective

Assignments

Source

Details

Est.

Time

lReview

ReviewAny

RemainingTopicsandfinishpracticequestions.

4hrs

mLogistics

Prepareexambag-withID,

ticket,directionsto

center,lunch.

t&Relax

28-day step 1 study schedule

Documents