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Room 17.P1.E3 09:30 Introduction to ADMET, Membrane and Transport Mechanisms Fernando Remião 10:15 MOOC TOX-OER - module 2.1 ADMET, Membrane and Transport Mechanisms Fernando Remião 11:00 Self-assessment and discussion 11:15 Coffee-break 11:30 Journal Club/Peer Learning/Discussion (Part-I) Fernando Remião/Félix Carvalho/Helena Carmo 12:30 Lunch at ICBAS | FFUP Canteen Room 13.P1.E3 14:00 Introduction to Membrane Transporters :: Lecture Fernando Remião 14:45 MOOC TOX-OER – module 2.2 ABC Transporters, BBB Barrier Fernando Remião 15:30 Self-assessment and discussion 15:45 Coffee-break 16:00 Journal Club/Peer Learning/Discussion (Part-II) Fernando Remião/Félix Carvalho/Helena Carmo 17:00—19:00 Visit to Rectorate and City Center Toxicology Laboratory 09:30 Introduction to Laboratory Class: Everted intestinal gut sac – evaluation of P-glycoprotein activation :: Lecture Carolina Amorim/Alfredo Paso 10:00 Laboratory Class: Everted intestinal gut sac – evaluation of P-glycoprotein activation 12:00 Discussion of the results 12:30 Lunch at ICBAS | FFUP Canteen Room 16.P1.E3 14:00 Introduction to Absortion, Distribution, Excretion :: Lecture Fernando Remião 14:45 MOOC TOX-OER – module 2.3 Absortion, Distribution, Excretion Fernando Remião 15:30 Self-assessment and discussion 15:45 Coffee-break 16:00 Journal Club/Peer Learning/Discussion (Part-III) Fernando Remião/Félix Carvalho/Helena Carmo 17:00—18:00 Visit to National Museum Soares dos Reis www.museusoaresdosreis.gov.pt/en-GB/default.aspx Room Sala do Conselho 10:00 Welcome to the University of Porto, Faculty of Pharmacy and Laboratory of Toxicology Director of Faculty and Director of the Lab. of Toxicology Room 15.P1.E3 10:30 Introduction of the Course and to the TOX-OER project Fernando Remião 11:00 Presentation of the course, Informatics Assistance and visit to the Faculty and Toxicology Laboratory 12:30 Lunch at ICBAS | FFUP Canteen Room Anfiteatro 5 14:00 Pharmaco/Toxicokinetics and Microbiota :: Lecture Maria de Lourdes Bastos 15:00 Pharmaco/Toxicokinetics – General Aspects :: Lecture Fernando Remião 16:15—18:00 Visit to Pharmacy Museum Porto www.museudafarmacia.pt/pagina.aspx?id=9 23 rd OCT MONDAY 24 th OCT TUESDAY 25 th OCT WEDNESDAY INTENSIVE LEARNERS MEETING Pharmaco/Toxicokinetics PROGRAM October 23-29, 2017 1/2

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Room 17.P1.E3 09:30Introduction to ADMET,Membrane and Transport MechanismsFernando Remião

10:15MOOC TOX-OER - module 2.1 ADMET, Membrane and Transport MechanismsFernando Remião

11:00Self-assessment and discussion

11:15Co�ee-break

11:30Journal Club/Peer Learning/Discussion (Part-I) Fernando Remião/Félix Carvalho/Helena Carmo

12:30Lunch at ICBAS | FFUP Canteen

Room 13.P1.E314:00Introduction to Membrane Transporters :: LectureFernando Remião

14:45MOOC TOX-OER – module 2.2 ABC Transporters, BBB Barrier Fernando Remião

15:30Self-assessment and discussion

15:45Co�ee-break

16:00Journal Club/Peer Learning/Discussion (Part-II) Fernando Remião/Félix Carvalho/Helena Carmo

17:00—19:00Visit to Rectorate and City Center

Toxicology Laboratory09:30Introduction to Laboratory Class: Everted intestinal gut sac – evaluation of P-glycoprotein activation :: LectureCarolina Amorim/Alfredo Paso

10:00Laboratory Class: Everted intestinal gut sac – evaluation of P-glycoprotein activation

12:00Discussion of the results

12:30Lunch at ICBAS | FFUP Canteen

Room 16.P1.E314:00Introduction to Absortion, Distribution, Excretion :: LectureFernando Remião

14:45MOOC TOX-OER – module 2.3 Absortion,Distribution, Excretion Fernando Remião

15:30Self-assessment and discussion

15:45Co�ee-break

16:00Journal Club/Peer Learning/Discussion (Part-III) Fernando Remião/Félix Carvalho/Helena Carmo

17:00—18:00Visit to National Museum Soares dos Reiswww.museusoaresdosreis.gov.pt/en-GB/default.aspx

Room Sala do Conselho10:00Welcome to the University of Porto, Facultyof Pharmacy and Laboratory of Toxicology Director of Faculty and Directorof the Lab. of Toxicology

Room 15.P1.E310:30Introduction of the Course and to the TOX-OER project Fernando Remião

11:00 Presentation of the course, Informatics Assistance and visit to the Faculty and Toxicology Laboratory

12:30Lunch at ICBAS | FFUP Canteen

Room Anfiteatro 514:00 Pharmaco/Toxicokinetics and Microbiota :: LectureMaria de Lourdes Bastos

15:00Pharmaco/Toxicokinetics – General Aspects :: LectureFernando Remião

16:15—18:00Visit to Pharmacy Museum Portowww.museudafarmacia.pt/pagina.aspx?id=9

23rd OCTMONDAY

24th OCTTUESDAY

25th OCTWEDNESDAY

INTENSIVE LEARNERS MEETINGPharmaco/Toxicokinetics

PROGRAMOctober 23-29, 2017

1/2

Room 17.P1.E3 09:30Journal Club/Peer Learning/Discussion (Part-V)Fernando Remião/Félix Carvalho/Helena Carmo

11:00Journal Club Presentations Maria de Lourdes Bastos/Fernando Remião/Félix Carvalho/Helena Carmo

12:30Lunch at ICBAS | FFUP Canteen

Room 15.P1.E314:00MOOC TOX-OER – exploring other contentsFernando Remião

15:00Overall discussion about Pharmaco/Toxicokinetics Fernando Remião

16:00—18:00Visit to Hall of Biodiversity of the University of Portohttps://mhnc.up.pt/galeria-da-biodiversidade/

Room 15.P1.E310:00Students assessment in TOX-OER Moodle platform Fernando Remião

11:15Discussion about assessment results

12:00Students survey course and MOOC TOX-OER

12:30Lunch at FLUP Canteen

14:00—18:00Cultural activities(Suggestions, not covered by the program)

Casa da Músicavisit at 16h: 3,50€www.casadamusica.com/

Serralves Contemporary Art Museum3,20€www.serralves.pt/en/

Room 15.P1.E309:30Introduction to Xenobiotic Metabolism :: LectureFernando Remião

10:15MOOC TOX-OER – module 2.4 Xenobiotic MetabolismFernando Remião

11:00 Self-assessment and discussion

11:15Co�ee-break

11:30Journal Club/Peer Learning/Discussion (Part-IV) Fernando Remião/Félix Carvalho/Helena Carmo

12:30Lunch at ICBAS | FFUP Canteen

Toxicology Laboratory14:00 Introduction to Laboratory Class: Paracetamol Bioactivation – in vitro evaluation of GSH depletion Renata Silva/Vera Costa

14:30Laboratory Class: Paracetamol Bioactivation – in vitro evaluation of GSH depletion

16:30Discussion of the results

17:00—18:00Visit to Gardens of Palácio de Cristalwww.cm-porto.pt/jardins-e-parques-urbanos/pala-cio-de-cristal_33

26th OCTTHURSDAY

27th OCTFRIDAY

Conclusion, Delivery of Participation Certificate

Departure of students

28th OCTSATURDAY

29th OCTSUNDAY

INTENSIVE LEARNERS MEETINGPharmaco/Toxicokinetics

PROGRAMOctober 23-29, 2017

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