COMPUTER-AIDED CHEMICAL ENGINEERING, 32

231U EUROPEAN

SYMPOSIUM ON

COMPUTER AIDED

PROCESS ENGINEERING

Editedby

Andrzej Kraslawski

Lappeenranta University of Technology, Finland

Ilkka Turunen

Lappeenranta University of Technology, Finland

Amsterdam - Boston - Heidelberg - London - New York - Oxford

Paris - San Diego - San Francisco - Singapore - Sydney - Tokyo

ELSEVIER University of Technology

Contents

Preface xix

International Program Committee xx

National Organising Committee xxii

Biomaterial Processing

1. Biomass Pyrolysis Kinetics Through Thermogravimetric Analysis/. Diaz, M. Rodriguez, C. Arnaiz, G. San Miguel and M. Domingiiez 1

2. Alternatives for the Production ofBiodiesel by Supercritical Technologies:A Comparative StudyFernando I. Gomez-Castro, Juan G. Segovia-Hernandez, Salvador

Hernandez-Castro, Vicente Rico-Ramirez, Zeferino Gamino-ArroyoandIrene Cano-Rodriguez 7

3. Simulation and optimization of a biojet fuel production processClaudia Gutierrez-Antonio, Fernando Israel Gomez-Castro, Juan Gabriel

Segovia-Hernandez andAbel Briones-Ramirez 13

4. Conceptual design ofhydrogen production process from bioethanol

reformingCalin-Cristian Cormos, ArpadImre-Lucaci, Ana-Maria Cormos,

Zsolt Tasnadi-Asztalos and Mihaela Diana Lazar 19

5. A combination of experiments and molecular dynamics simulation for the

investigation of the ion-exchange adsorption of biological macromolecules

Juan Liang and Georg Fieg 25

6. Integrated optimization ofblack tea cream effect using statistical analysisM. Monsanto, E. Zondervan and J. Meuldijk 31

7. Modelling, design and operation of a pretreatment reactor

for lignocellulosic biomassTeresa Lopez-Arenas, Mauricio Sales-Cruz, Jesus Alvarez

and Alexander Schaum 37

8. Regulatory Control for the Operation of a Simultaneous Saccharification

and Co-Fermentation Reactor for Bioethanol Production

H. Hernandez-Escoto, D. Rodriguez-Gomez and R. Morales-Rodriguez 43

9. Chemometrics for analytical data mining in separation process designfor recovery of artemisinin from Artemisia annua

Chandrakant R. Malwade, Haiyan Qu, Ben-Guang Rong and Lars

P. Christensen 49

10. Production of Methanol and Dimethyl ether from biomass derived

syngas - a comparison of the different synthesis pathways by means

of flowsheet simulation

M. Gqdek, R. Kubica andE. Jedrysik 55

v

vi Contents

11. Prediction of biopharmaceutical facility fit issues using decision tree analysis

Yang Yang, Suzanne S. Farid and Nina F. Thornhill 61

12. Sugar hydrogenation- combined heat and mass transfer

Teuvo Kilpid, Petteri Snominen and Tapio Salmi 67

13. Multi-period Synthesis of a Biorefinery's Supply Networks

Lidija Cucek, Mariano Martin, Ignacio E. Grossmann

andZdravko Kravanja 13

14. Modeling Integrated Biorefinery Supply Chains

Helena Paulo, Ana Paula F. D. Barbosa-Pdvoa and Susana Relvas 79

15. Kinetics ofthe Enzymatic Cellulose Hydrolysis by the Endoglucanasefrom the Extremophile S. solfataricus

Benjamin Bonhage, Bianca Seiferheld and Antje C. Spiess 85

16. A systematic methodology for optimal product design in an integrated

biorefineryNishanth G, Chemmangattuvalappil andDenny K.S. Ng 91

17. Effective Optimization Model for Biomass DryingTesfaldet Gebgeegziabher, Adetoyese Olajire Gyedun.Yu Zhangand Chi Wai Hui 97

18. Model-based run-to-run optimization under uncertaintyof biodiesel productionMartin F. Luna and Ernesto C. Martinez 103

19. Predictive Control Strategy for Temperature Control

for Milk Pasteurization Process

Sathit Niamsuwan, Paisan Kittisupakorn andIqbal M. Mujtaba 109

20. A model based approach to an adaptive design space in chromatographyEdward Close, Daniel G Bracewell and Eva Sorensen 115

21. Metabolic pathways analysis in PHAs production by Pseudomonas with

13C-labeling experimentsCarlos A. M. Riascos, Andreas K. Gombert, Luiziane F. Silva,

Marilda K. Taciro, Jose G. C Gomez and Galo A. C. Le Roux 121

22. Implementation aspects of modeling equilibrium reactions

and thermodynamic data in a flowsheet simulator

Kaj Jakobsson, Susanna Kuitunen and Ville Alopaeus 127

Biomedical Engineering

23. Identification of complex models of type 2 diabetes from IVGTT data

by model-based design of experimentsFederico Gah anin, Massimi/iano Barolo, Riccardo C. Bonadonna

andFabrizio Bezzo 133

Contents

24. An Integrated Computational Model ofPowder Release, Dispersion,Breakage, and Deposition in a Dry Powder Inhaler

A.H. Alexopoulos, J. Milenkovic and C. Kiparissides

25. Scaling the Endocrine System from Rats to Humans

German Campetelli, Mercedes Lombarte, Marta S. Basualdo

andAlfredo Rigalli

26. Design of vascular tree for organ biprinting

Rodrigo A. Rezende, Vladimir Kasyanov, Iveta Ozolanta, Ken Brakke,

Jorge V. L. da Silva and Vladimir Mironov

27. Mixed integer optimization of antibody purification processes

Songong Liu, Ana S. Simaria, Suzanne S. Farid

andLazaros G Papageorgiou

28. Novel two-steps optimal control of batch polymerization reactors

and application to PMMA production for the fabrication

of artificial bone tissue

Nadson M. N. Lima, Lamia Zuniga Linan.Flavio Maneti,

Rubens Maciel Filho, Marcelo Embrucu and Maria R. WolfMaciel

29. Using an Iterative Dynamic Programming Algorithm to Solve

an Immunotherapy Model

Carlos E. Lopez-Landeros, Nilton J. Carbajal-Palacios,Julissa E. Cosme-Castorena and Sergio Frausto-Hernandez

30. Structure Based Design of Non-Peptide Mimetics

Robert H. Herring III, J. Colin Haser, Subin Hada and Mario R. Eden

31. Genome-scale metabolic network reconstruction and in silico analysisofMethanococcus maripaludis S2

Nishu Goyal% Hanifah Widiastuti, Iftekhar A. Karimi and Zhou Zhi, George

Energy Systems

32. Techno-Economic Analysis of a Natural Gas Combined Cycle PowerPlant with C02 CaptureChechet Biliyok, Roberto Canepa, Meihong Wang and Hoi Yeung

33. A Superstructure Based Mixed-integer Programming Approachto the Optimal Design of a Pipelines Network for CO2 Transport

Chengchuan Zhou, Pei Liu and Zheng Li

34. Evaluation of chemical looping systems as carbon capture optionto be applied to gasification processes

Calin-Cristian Cormos, Ana-Maria Cormos andSerban Agachi

35. Building modeling: on selection of the model complexityfor predictive control

Eva Zdcekovd, Samuel Privara, Zdenek Vana andJifi Cigler

Vlll Contents

36. Dual control within MPC framework

Eva Zdcekova and Samuel Privara 211

37. Optimization of an Ethanol Dehydration Process Using Differential

Evolution AlgorithmMaria Vdzquez-Ojeda, Juan Gabriel Segovia-Hernandez,Salvador Hernandez, Arturo Herndndez-Aguirre andAnton Alexandru Kiss 217

38. Reactive distillation for production of «-butyl aerylate from bio-based raw

materials

Alexander Niesbach, Philip Lutze andAndrzej Gorak 223

39. Large-Scale Validation of a Numerical Model of Accidental Releases

from Buried C02 PipelinesC, J. Wareing, R. M. Woolley, M. Fairweather, S. A. E. G. Falle

and R. P. Cleaver 229

40. Operation of energy efficient divided wall column

Ambari Khanam, M. Shamsuzzoha and Sigurd Skogestad 235

41. Using External Recycle for Design of Reactive Distillation Columns

Haisheng Chen andKejin Huang 241

42. A Three Dimensional Dynamic CFD Simulation

for the Direct DME Production in a Fixed Bed Reactor

Fazel Moradi, Mohammad Kazemeini, Leila Vafajoo and Moslem Fattahi 247

43. Inertial Particle Behaviour in Turbulent Fluid Flow

D. O. Njobuenwu and M. Fairweather 253

44. Resource-Task Network Based Approach for Industrial Demand Side

Management of Steel Production

Lige Sun, liro Harjunkoski and Pedro Castro 259

45. Computer-aided Modeling and Optimization of Thermal Efficiencyfor Multi-fuel Boiler

Jian-Guo Wang, Jia-Lin Kang, Shyan-Shu Shieh, Shi-ShangJangand David Shan-Hill Wong 265

46. A Parallel Method with Hybrid Algorithms for Mixed Integer Nonlinear

ProgrammingKai Zhou, Wei Wan, Xi Chen, Zhijiang Shao andLorenz T. Biegler 271

47. Reactive Scheduling of micro Combined Heat and Power Systems via

Multiparametric Programming

Georgios MKopanos and Efstratios N. Pistikopoulos 277

48. Modelling and identification of the dominant phenomena in hydrogenfuel-cells by the application of DRT AnalysisVitor V. Lopes, Carmen M. Rangel andAugusto Q. Novais 283

Contents ix

49. Molecular Design ofWorking Fluid Mixtures for Organic Rankine CyclesAthanasios I Papadopoulos, Mirko Stijepovic, Patrick Linke,

Panos Seferlis and Spyros Voutetakis 289

50. A Novel Hybrid Direct Search Method for Constrained Non-Smooth

Black-Box Problems

Emanuele Martelli and Edoardo Amaldi 295

51. Limestone dissolution study for Wet Flue Gas Desulfurization under

turbulent regimes above critical suspension speedClaudio Carletti, Henrik Grenman, CataJdo De Blasio and TapioWesterlund 301

52. Intensifying heat transfer for retrofitting heat exchanger networks

with topology modifications

Ming Pan, Robin Smith andIgor Bulatov 307

53. A Conceptual Design Algorithm for Single-Feed Hybrid Reactive

Distillation Column involving azeotropic systems

Shabih Ul Hasan, Sanjay M. Mahajani andRanjan K. Malik 313

54. On-line modeling of NOx formation in a coal boiler

Achim Wechsung andPaul I. Barton 319

55. Supervisory Control for Real Time Reactive Power Flow Optimizationin Islanded MicrogridsAdam Milczarek, Juan C. Vasquez, Mariusz Malinowski,

Josep M. Guerrero and Moises Graells 325

56. On the synthesis of multicomponent distillation configurationswith nonsharp splits

Ben-Guang Rong 331

57. Multi-objective optimization of SNG production through hydrothermalgasification from microalgaeAlberto Mian, Adriano V. Ensinas and Francois Marechal 337

58. Model-based Assessment ofthe Role of Natural Gas-based Micro-CHP

in Residential Energy Supply SystemsTekena Fubara, Franjo Cecelja and Aidong Yang 343

59. Energy Integration in the cement industryAlberto Mian, Matthias Bendig, Gaia Piazzesi, Giovanni Manente,

Andrea Lazzaretto and Francois Marechal 349

60. Estimation ofenhanced heat transfer area targets in process industries

Olga P. Arsenyeva, Robin Smith, Igor Bulatov, Leonid L. Tovazhnyanskyy,Petro O. Kapustenko and Gennadiy L.Khavin 355

61. Capital Cost Assessment for Total Site Power CogenerationStanislav Boldyryev, Petar Sabev Varbanov, Andreja Nemet,Jifi Jaromir Klemes and Petro Kapustenko 3 61

62. Process engineering method for systematically comparing C02 capture

optionsLaurence Tock andFrancois Marechal

63. Optimal synthesis and design of extractive distillation systemsfor bioethanol separation: from simple to complex columns

Massimiliano Errico, Ben-Guang Rong and Giuseppe Tola

64. Modeling and Simulation for Absorption-Desorption Cyclic Process on

a Three-Stage Metal Hydride Hydrogen Compressor

Evangelos I. Gkanas, Sofoklis S. Makridis and Athanasios K. Stubos

65. Convex Relaxations ofMulti-variate Composite Functions

Angelos Tsoukalas and Alexander Mitsos

66. Optimization ofbinary geothermal power systemsHadi Ghasemi, Alessio Tizzanini, Marco Paci and Alexander Mitsos

67. Profit optimization for bio-gas upgrading PSA process based

on controlling step-timeSeimgnam Kim, Jinkyung Kim and II Moon

68. Continuous-time Batch Scheduling Approach for Optimizing ElectricityConsumption Cost

Hubert Hadera and Iiro Harjunkoski

69. CPU Heat Sink Cooled by Nanofluids and Water: Experimentaland Numerical StudyMateusz Korpys, Mohsen Al-Rashed, Grzegorz Dzido andJanusz Wdjcik

70. GWh Level Renewable Energy Storage and Supply using Liquid C02Easa I. AUmusleh, Dharik S. Mallapragada and Rakesh Agrawal

71. Simulation, Analysis, and Assessment of C02 Enhanced Biomass

Gasification

Narendra Sadhwani, Zheng Liu, Mario R. Eden andSushilAdhikari

72. Forecasting C02 emissions due to gasifier degradation by time-series

analysisMar Perez-Fortes, Elisabet Capon-Garcia andLuis Puigjaner

73. Heat Exchanger Network Design and Economic Analysisfor Coal-fired Power Plant retrofitted with C02 CaptureSalihu Adamu Girei, Meihong Wang andAminu Alhaji Hamisu

74. Overall Optimization of a Comprehensive Utility SystemMkhokheli Ndlovu and Thokozani Majozi

75. Constraint handling in stochastic optimization algorithms for natural gas

liquefaction processes

Bjom Austbo, Per E. Wahl and Truls Gundersen

Contents xi

76. Dynamic modelling and control of a pilot plant for post-combustionC02 capture

Gregoire Leonard, Bruno Cabeza Mogador, Segolene Belletante

and Georges Heyen 451

77. Enhanced configurations for polyesters synthesis by reactive distillation

Mayank Shah, Anton A. Kiss, Edwin Zondervan and Andre B. de Haan 457

78. Multi-objective, multi-period optimization of district energy systems:Networks designSamira Fazlollahi, Gwenaelle Becker, Michael Guichard

and Francois Marechal 463

Management & Economics

79. A Metaheuristic Optimization Algorithm for Binary Quadratic Problems

Otto Nissfolk and Tapio Westerlund 469

80. Risk management in the design and planning of closed-loop supply chains

Sonia R. Cardoso, Ana Paula F. D. Barbosa-Pdvoa and Susana Relvas 475

81. Integrated scheduling and control ofa polymerization reactor

with online closed-loop implementationYunfei Chu and Fengqi You 481

82. Reformulation strategies for eigenvalue optimization using Sylvester'scriterion and Cholesky decompositionDanan S. Wicaksono and Wolfgang Marquardt 487

83. Design ofBiofuel Supply Chains under Uncertainty with MultiobjectiveStochastic Programming Models and Decomposition AlgorithmFengqi You 493

84. Intelligent Alarm System applied to Continuous Pharmaceutical

ManufacturingAnshu Gupta, Arun Giridhar, Ginataras V. Reklaitis and Venkat

Venkatasubramanian 499

85. A multiproduct batch plant design model incorporating production

planning and scheduling decisions under a multiperiod scenario

Yanina Fumero, M. Susana Moreno, Gabriela Corsano

andJorge M. Montagna 505

86. Supporting the transfer ofproducts between different equipmentthrough latent variable model inversion

N. Meneghetti, E. Tomba, P. Facco, F. Lince, D. L. Marchisio,

A. A. Barresi, F. Bezzo andM. Barolo 511

87. Tactical Planning with Shelf-Life Constraints in the FMCG IndustryM. A. H. van Elzakker, E. Zondervan, N. B. Raikar, H. HooglandandI. E. Grossmann 517

xii Contents

88. OFIS - Ontological Framework for Industrial SymbiosisNikolaos Trokanas, Tara Raafat, Franjo Cecelja and Antonis Kokossis 523

89. Refinement strategies for piecewise linear functions utilized

by reformulation-based techniques for global optimizationAndreas Lundell and Tapio Westerlund 529

90. A comparison of two convex underestimation methods for quadraticfunctions

Andres Skjdl and Tapio Westerlund 535

91. A new methodology to identify supply chains sustainability bottlenecks

Ana Carvalho andAna Paula F.D. Barbosa-Pdvoa 541

92. Simplified model for integrated Supply Chains PlanningMiguel Zamarripa, Kefah Hjaila, Javier Silvente and Antonio Espuna 547

93. Hybrid time representation for the scheduling of energy supplyand demand in smart gridsJavier Silvente, Adrian Aguirre, Guillem Crexells, Miguel Zamarripa,Carlos Mendez, Moises Graells andAntonio Espuna 553

94. Supply Chain Management - Optimal Planningfor Sustainable Products'

PortfolioA.C.S. Amaw andA.P.F.D. Barbosa-Pdvoa 559

95. Evaluating the Effectiveness of Anticipatory Alarms for Proactive Process

Monitoring

AriefAdhitya, Siew Fun Cheng, Zongda Lee andRajagopalan Srinivasan 565

96. Medium-Term Production Scheduling of Large-Scale SteelmakingContinuous Casting Process under Demand UncertaintyYun Ye, Jie Li, Zukui Li, Qiuhua Tang, Xin Xiao and Christodoulos

A. Floudas 571

97. Design of Supply Chains under the Risk of Facility DisruptionsPablo Garcia-Herreros, lgnacio E. Grossmann andJohn Wassick 577

98. A Multiproduct Feedstock Optimization Model for Polymer Production

Pablo A. Marchetti, lgnacio E. Grossmann, Wiley BuceyandRita A. Majewski 583

99. A comprehensive CP approach for the scheduling of resource-constrained

multiproduct multistage batch plantsFranco M. Novara, Juan M. Novas and Gabriela P. Henning 589

100. A Mixed Integer Linear Program decomposition solution to the schedulingactivities in a real-world pipeline used to transport heavy oil derivatives

Joao A. Fabro, Sergio L. Stebel, L. V. R. Am/da, Fldvio Neves Jr.,Ana Paula F. D. Barbosa-Pdvoa and Susana Relvas 595

Contents xiii

101. Framework to Generate Engineering Standard for Plant Maintenance

Tetsuo Fuchino, Yukiyasu Shimada, Teiji Kitajima, Kazuhiro Takeda

and Masazumi Miyazawa 601

102. Overview for Management of Change based on Business Process Model

ofPlant LifecycleKazuhiro Takeda, Hideo Saito, Yukiyasu Shiamad, Teiji Kitajima,Tetsuo Fuchino and Yuji Naka 607

103. Development of a Sustainable Copper Scrap Management Model

Marie Bonnin, Catherine Azzaro-Pantel, Ludovic Montastruc,Luc Pibouleau, Serge Domenech andJacques Villeneuve 613

104. Forecasting research trends using population dynamics model

with Burgers' type interaction

Matylda Jablonska, Robert Sitarz andAndrzej Kraslawski 619

105. Reliability of operating window identified from process data

Heimo lhalainen, Risto Ritala and Olli Saarela 625

106. An improved M1LP model for scheduling crude oil unloading, storageand processingAminu A. Hamisu, Stephen Kabantiok and Meihong Wang 631

107. Mathematical Knowledge Management for Enterprise Decision MakingEdrisi Muhoz, Elisabet Capdn-Garcia, Jose M. Lainez, Antonio EspunaandLuis Puigjaner 637

108. A spatially-explicit approach to the design of ethanol supply chains

considering multiple technologies and carbon trading effects

R. A. Ortiz Gutierrez, S. Penazzi, A. Bernardi, S. Giarola andF. Bezzo 643

109. An Efficient MILP Approach for the Short-Term Planning ofRefined

Products Blending and Distribution OperationsAgustin F. Montagna, Diego C. Cafaro andJaime Cerdd 649

110. A Novel Graphical Method for Controllability Analysis of Chemical

Process DesignsAfshin Sadrieh and Parisa A. Bahri 655

111. Design of a Generic and Flexible Data Structure for Efficient

Formulation of Large Scale Network Problems

Alberto Quaglia, Bent Sarup, Giirkan Sin andRafiqul Gani 661

112. Testing and analyzing different training methods for industrial operators:an experimental approachSalman Nazir, Simone Colombo and Davide Manca 667

113. Design and Optimization of Biofuel Supply Chain Network in UK

Mingyen Yu, Franjo Cecelja and Seyed Ali Hosseini 673

xiv Contents

114. A methodology to forecast the price of electric energyDavide Manca 679

115. Improving Lead Time of Sterile Drug Product Manufacturing UsingMonte Carlo Simulation

Lakas Eberle. Hirokazu Sugiyama and Rainer Schmidt 685

116. Multi-stage stochastic optimization of the design and planningof a Closed-Loop Supply Chain

Luis J. Zeballos, Carlos A. Mendez, Ana P. Barbosa-Povoa

and Augtisto Q. Novais 691

117. Business Model of Continuous Improvement in Pharmaceutical

Production Processes

Hirokazu Sugiyama andRainer Schmidt 697

Sustainability of Products and Processes

118. Leak Identification in a Water Distribution Network using Sparse FlowMeasurements

M. Mulholland, A. Purdon, M.A. Latifi, C.J. Brouckaert and C.A. Buckley 703

119. Multi-objective optimisation ofthe operation of a water distribution network

M. Mulholland, M.A. Latifi, A. Purdon, C.A. Buckleyand C.J. Brouckaert 709

120. A methodology for simultaneous product and process designin the customer products industry: The case studyof the laundry business

Mariano Martin and Alberto Martinez 715

121. Dynamic optimization of semi-batch emulsion copolymerization reactor

for styrene/butyl acrylate in the presence of a chain transfer agentR. Paulen, B. Benyahia, M. A. Latifi and M. Fikar 721

122. Eco-design and Life Cycle Assessment of a chemical process:

the case study ofHDAAdama Ouattara, Luc Pibouleau, Catherine Azzaro-Pantel

and Serge Domenech 111

123. Life Cycle Energy, Environmental and Economic Comparative

Analysis of CdTe Thin-film Photovoltaics Domestic

and Overseas Manufacturing Scenarios

Yuan Yao and Fengqi You 733

124. Optimization of Batch and Semi-batch Reactors

Ergys Pahija. Flavio Manenti andIqbal M. Mujtaba 739

125. Decision tool for the selection among different reverse osmosis

membranes for hydrogen peroxide ultrapurificationRicardo A bejon. Aurora Garea andAngel Irabien 745

Contents xv

126. Process Fault Diagnosis Based on Bayesian Inference

Jialin Liu, Shu Jie Liu andDavid Shan Hill Wong 751

127. Hybrid advanced control of flexible multipurpose continuous tablet

manufacturing process via direct compactionRavendra Singh, Marianthi Ierapetritou andRohit Ramachandran 757

128. A hybrid GA-SQP multi-objective optimization methodologyfor carbon monoxide pollution minimization in Fluid Catalytic

Cracking Process

Jose F. Cuadros, Delba N. C. Melo, Nddson M. Nascimento,Rubens Maciel Filho and Maria R. WolfMaciel 763

129. Control ofa Biological Nitrogen Removal Process in an Intensified

Single Reactor ConfigurationAnna Katrine Vangsgaard, Miguel Mauricio-Iglesias, Krist V. Gernaey,Barth F. Smets and Giirkan Sin 769

130. Computer-aided modeling framework - a generic modeling templatefor catalytic membrane fixed bed reactors

Marina Fedorova, Gurkan Sin andRafiqul Gani 775

131. Model based optimal experimental design - a semi-definite

programming approach applied to a solvent design problemBelmiro P. M. Duarte andNuno M. C. Oliveira 781

132. Control of the particle size distribution in emulsion polymerization

by mid-course correction using a hybrid model

Alireza Hosseini, Milad Oshaghi and Sebastian Engell 787

133. Optimization of bio-hydrogen production and C-N removal in combined

anaerobic-aerobic systemsMauren Fuentes, Pio A. Aguirre and Nicolas J. Scenna 793

134. Optimal Design of SWRO Desalination Processes with Boron Level

Considerations

Sabla Y. Alnouri and Patrick Linke 799

135. Selecting the best control methodology to improve the efficiencyofdiscontinuous reactors

Ergys Pahija, Flavio Manenti and Iqbal M. Mujtaba 805

136. Total plant integrated optimization of sulfur recovery and steam

generation for Claus processes using detailed kinetic schemes

Flavio Manenti, Davide Papasidero, Giulia Bozzano, Sauro Pierucci,

Eliseo Rami and Guido Buzzi-Ferraris 811

137. Design ofan Emulsion-based Personal Detergent througha Model-based Chemical Product Design MethodologyMichele Mattel, Michael Hill, Georgios M. Kontogeorgisand Rafiqul Gani 817

xvi Contents

138. Industrial Application of Sustainable Retrofit DesignPedro Chainho, Ana Carvalho andHenrique A. Matos 823

139. Geometry optimization of photochemical reactors for advanced

oxidation processesT. Coenen, F. Logist, W. Van de Moortel, J. Luyten, J. Van ImpeandJ. Degreve 829

140. Design of Sustainable Blended Products using an Integrated MehtodologyNor Alafiza Yimus, Krist V. Gernaey, John M. Woodley andRafiqul Gani 835

141. A Modeling Approach for Dispersive Mixing of Oil in Water Emulsions

Arend Dubbelboer, Jo Janssen, Hans Hoogland, Ashvin Mudaliar, Edwin

Zondervan, Peter M. M. Bongers and Jan Meuldijk 841

142. Particle-Interaction Effects in Turbulent Channel Flow

M AJkhami, A. Hassanpour, M. Fairweather and D. O. Njobuenwu 847

143. Sensitivity-based Mnemonic Enhancement Optimization (S-MEO)for Real-time Optimization of Chemical Process

Weifeng Chen, Lingyu Zhu, Xi Chen, Zuhua Xu and Zhijiang Shao 853

144. Prediction of the Full Molecular Weight Distribution in RAFT

Polymerization using Probability Generating Functions

Cecilia Fortanatti, Claudia Sarmoria, Adriana Brando/in

and Mariano Asteasuain 859

145. INOSIM Bio - new approaches for bioprocess simulation and optimizationKatrin Sttlzbacher, Peter Balling and Gerhard Schembecker 865

146. APROS-NIMBUS: Dynamic Process Simulator and Interactive

Multiobjective Optimization in Plant Automation

Karthik Sindhya, Vesa Ojalehto, Jouni Savolainen, Hannu Niemisto,

Jussi Hakanen andKaisa Miettinen 871

147. Spatially Distributed Fines Removal in a Continuous Plug Flow

Crystallizer by Optimal Temperature Profile with Controlled Dissolution

Aniruddha Majumder and Zoltan K. Nagy 877

148. Cellular automata modeling of dissolution ofsolid-dosage forms

S.J. Ivanov, D.D. Lovskaya and N. V. Menshutina 883

149. A framework for sustainability of coal based energy and chemical

processes

Siyu Yang, Xiaoping Jia, Chen Yun and Yu Qian 889

150. Towards supply chain sustainability: balancing costs with environmental

and social impactsBnma Mota, Maria Isabel Gomes and Ana Paula Barbosa-Povoa 895

151. Fault-Tolerant Self-Reconfigutable Control SystemManuel Rodriguez, Jose Luis de la Mata and I. Diaz 901

Contents xvii

152. Optimal design of a solid-liquid separation systemRonald Cruz, Luis A. Cisternas and Edelmira D. Galvez 907

153. Global sensitivity analysis of a mineral processing flowsheet

Felipe D. Sepulveda, Luis A. Cisternas and Edelmira D. Galvez 913

154. An Integrated Platform for Optimization ofHeat and Water Use

in Multipurpose Batch Plants

Esmael R. Seid and Thokozani Majozi 919

155. Control System Development for Integrated Biological Waste Water

Treatment Process of a Paper Production Plant

Alicia Roman-Martinez, PastorLanuza-Perez, MargaritoCepeda-Rodriguez andElvia M. Mata-Padron 925

156. Applicability of Sustainability Indicators to Wastewater Treatment

Processes

Tamara Popovic, Andrzej Kraslawski and Yury Avramenko 931

157. An Uncertainty Assessment Framework for LCA-based Environmental

Process DesignJohannes Jung, Niklas von der Assen andAndre Bardow 937

158.. Optimal recipe design for Paracetamol degradation by advanced

oxidation processes (AOPs) in a pilot plantM. Moreno-Benito, E. Yamal-Turbay, A. Espuna, M. Perez-Moya and

M. Graells 943

159. Efficient Waste Management based on Scheduling OptimizationofWaste Treatment Plants

Elisabet Capdn-Garcia, Stavros Papadokonstantakisand KonradHungerbuhler 949

160. Design of Ionic Liquids Using Property Clustering and Decomposition

TechniquesSubin Hada, Robert H. Herring III and Mario R. Eden 955

161. A novel approach to hybrid evolutionary-deterministic optimizationin process designMirko Skiborowski, Marcel Rautenberg and Wolfgang Marquardt 961

162. Control of a batch reactor using constrained direct inverse

Ldszlo Richard Toth, Lajos Nagy and Ferenc Szeifert 967

163. Taylor Models in Deterministic Global Optimizationfor Large-Scale Systems with Few Degrees of Freedom

Jai Rajyaguru andBenoit Chachuat 973

164. Enclosing the Reachable Set of Parametric ODEs using Taylor Models

and Ellipsoidal Calculus

Mario Villanueva, Radoslav Paulen, Boris Houska and Benoit Chachuat 979

xvm

165. Synthesis and design of optimal biorefinery using an expanded network

with thermochemical and biochemical biomass conversion platformsPeam Cheali, Krist V. Gernaey and Giirkan Sin

166. Automated HAZOP using hybrid discrete/continuous process models

Irene Lotero-Herranz andSantos Galdn

167. Advanced control strategy for NOx reduction in forced unsteady-state

reactors

Mihaela lancu, Clandiu C. Botar andPaul S. Agachi

168. Advanced Control Used for Counteracting Accidental Pollutant

Propagation in Rivers

Vasile-Mircea Cristea, Elisabeta-Cristina Ani andPaul Serban Agachi

169. Nonlinear process monitoring by integrating manifold learningwith Gaussian process

Yuan-Jui Liu, Tao Chen and Yuan Yao

170. Dynamic effects of diabatization in distillation columns

Thomas Bisgaard, Jakob KjobstedHuusom andJens Abildskov

171. On the integration of model identification and process optimizationSebastian Recker, Nimet Kerimoglu, Andreas Harwardt,

Olga Tkacheva and Wolfgang Marquardt

172. Introduction of social criteria for the optimal location of Construction

and Demolition Waste management facilities in Cantabria (Spain)Elena Dosal, Berta Galdn, Ana Andres and Javier Viguri

173. Optimization under Uncertainty ofPollutant DischargesReduction Strategies on Drainage SystemsValeria Pinedo-Miramontes, Sergio Frausto-Herndndez

and Javier G. Zapiain Salinas

174. Shortcut method for the design of extraction columns

for multi-component mixture separationsChristian Redepenning, Mirko Skiborowski and Wolfgang Marquardt

175. Modeling of Gold Leaching with Thiosulphate Solutions in Different

Types of Reactor

Vladimir Zhukov, Yury Sharikov and Ilkka Turunen

176. An agent based model for the exploration and assessment

of sulfur technology for upstream stranded gas fields

T.van der Lei, R.Boonstra, J. Veltman, E.van Kints, P.Herder

and F. Geuzebroek

Author Index