2015 workshop immunodeficiency and...

Society for Hematopathology/ European Association for Haematopathology

October 29 – 31, 2015Long Beach Convention CenterLong Beach, California

Immunodeficiency and Dysregulation

2015 Workshop

NEW!ASCP/SH DAYWednesday, Oct. 28See p.5 for details.

Society for Hematopathology/European Association for Haematopathology

Program Overview

Immunodeficiency and dysregulation can predispose to as well as mimic hematolymphoid malignancy. Recognition of an underlying immune defect can pose significant challenges to the pathologist and be instrumental in guiding workup and therapy of affected patients. The intersection of immunologic dysfunction and pathologic diagnosis is rapidly evolving as a result of recent advances in high-throughput genomic and proteomic technologies. The objectives of this workshop are to improve understanding of primary and secondary im-munodeficiencies and disorders of immune regulation and refine diagnostic criteria surrounding immunodeficiency-related hematopoietic malignancy and their separation from immune-mediated morphologic mimics. This forum will specifically focus on primary and secondary immunodeficiency and associated neoplasms, immune dysregulation including autoimmune, iatrogenic and viral-related lymphoproliferative disorders and post-transplant lymphoproliferative disorders. In addition, distinguished speakers will share their insights into human immune senescence, hematopoietic stem cells and ag-ing and high throughput strategies to interrogate lymphocyte repertoires in inherited and acquired immunodeficiency.

Program Committee

Yaso Natkunam, MD, PhD (Chair)

Dita Gratzinger, MD, PhD

Scott Boyd, MD, PhD

Robert Ohgami, MD, PhD

Department of Pathology Stanford University Sch of MedicineStanford, California, USA

Workshop Review Panel

Amy Chadburn, MD

John K.C. Chan, MD, FRCPath

Daphne de Jong, MD, PhD

Elaine S. Jaffe, MD

John Goodlad, MD, FRCPath

Dita Gratzinger, MD, PhD

Yaso Natkunam, MD, PHD

Jonathan Said, MD

October 29 – 31, 2015Long Beach Convention CenterLong Beach, California

Immunodeficiency and Dysregulation

2015 Workshop

This year the SH workshop is being held in conjunction with the ASCP annual meeting. This allows you to attend certain ASCP meeting functions in addition to this workshop. Please see schedule and additional registration option details enclosed.

2015 Workshop Immunodeficiency and Dysregulation

Faculty

Scott Boyd, MD, PhDStanford University Sch of MedicineStanford, CA

Ethel Cesarman, MD, PhDWeill Medical College of Cornell UniversityNew York, NY

Amy Chadburn, MDWeill Medical College of Cornell UniversityNew York, NY

John K.C. Chan, MD, FRCPathQueen Elizabeth HospitalHong Kong

Mark Davis, PhDStanford University School of MedicineStanford, CA

Daphne de Jong, MD, PhDNetherlands Cancer InstituteAmsterdam, The Netherlands

John Goodlad, MD, FRCPathUniversity of EdinburghUnited Kingdom

Dita Gratzinger, MD, PhDStanford University Sch of MedicineStanford, CA

Elaine S. Jaffe, MDNational Institutes of HealthBethesda, MD

Katherine Yudeh KingBaylor College of MedicineHouston, TX

Yaso Natkunam, MD, PHDStanford University Sch of MedicineStanford, CA

Robert Ohgami, MD, PhDStanford University Sch of MedicineStanford, CA

Stefania Pittaluga, MDNational Institutes of HealthBethesda, MD

Jonathan Said, MDUCLA Medical CenterLos Angeles, CA

Steven H. Swerdlow, MDUniversity of PittsburgPittsburg, PA

Educational Objectives

After attending the conference, participants should be able to: • Appraise current WHO

categories of immunodeficiency-related lymphoproliferative disorders, and identify areas of diagnostic difficulty (Knowledge, Competence, Performance)

• Correlate advances in molecular diagnostics and the molecular pathogenesis of primary (congeni-tal), post-transplant, infection-related, aging, autoimmune and iatrogenic immunodeficiencies and related lymphoproliferative disorders (Knowledge, Competence)

• Connect new clinical approaches to treatment and monitoring of patients with immunodeficiency-related lymphoproliferative disorders to hematopathology practice (Knowledge, Competence, Performance, Patient Outcomes)

Target Audience

This conference is designed for physi-cians and other health professionals in hematopathology, pathology, hematology and oncology.

Educational Methods

Lectures, Case Studies, Questions and Answers, Audience Response System

Evaluation

A course evaluation form will pro-vide participants with the opportu-nity to comment on the value of the program content to their practice decisions, performance improvement activities, or possible impact on pa-tient health status. Participants will also have the opportunity to com-ment on any perceived commercial bias in the presentations as well as to identify future educational topics.

Accreditation/ Credit Designation

The Society for Hematopathology in partnership with the American Soci-ety for Clinical Pathology designates this live activity for a maximum of 18 AMA PRA Category 1 CreditsTM. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

The American Society for Clini-cal Pathology is accredited by the Accreditation Council for Continu-ing Medical Education to provide continuing medical education for physicians.

CME Certificates and Attendance

Verification CertificatesCertificates awarding AMA PRA Category 1 CreditTM or certificates documenting attendance will be distributed to participants when the participant departs the confer-ence. To obtain a CME certificate, physicians must submit a completed evaluation questionnaire and a CME Verification Form. Upon request, a record of attendance (certificate) will be provided on–site to other health care professionals for requesting cred-its in accordance with state nursing boards, specialty societies, or other professional associations.

SAM CreditsThe Society for Hematopathology is partnering with the American Society for Clinical Pathology to provide American Board of Pathol-ogy (ABP)-approved Self-Assessment Module (SAM) credits. SAM credits are necessary to meet the ABP main-tenance of certification requirements. SAM credits will be available for this conference.


Types of Cases Featured in the Workshop

Lymphoproliferative disorders of primary (congenital) immunodeficiency• Lymphoproliferative neoplasms in the setting of chronic variable im-

munodeficiency (CVID), severe combined immunodeficiency (SCID), hyper-IgM syndrome, CD40/CD40 ligand deficiency, ataxia telangi-ectasia, autoimmune lymphoproliferative syndrome (ALPS), X-linked lymphoproliferative syndrome (XLP), chronic granulomatous disease (CGD), Nijmegen breakage syndrome (NBS) and related entities.

• Morphologic abnormalities or mimics of lymphoma in the setting of primary immunodeficiency or inherited immune disorders.

Post-transplant lymphoproliferative disorders (PTLD) • Particular focus will be given to uncommon categories or

controversial areas of PTLD with the goal of achieving better definitions and criteria for diagnosis

• Early lesions• Polymorphic PTLD and the border with monomorphic PTLD• EBV-negative PTLD• T-cell PTLD• Classical Hodgkin and Hodgkin-like PTLD

Infection-related lymphoproliferative disorders (excluding PTLD)• Lymphoproliferative disorders related to HCV,

HHV8 and other oncogenic viruses• HIV-associated lymphoma, with a focus on less common manifestations

(e.g. Burkitt with plasmacytoid differentiation, plasmablastic lymphoma)• Chronic active EBV (CAEBV)• EBV-positive T and NK cell lymphoproliferative disorders of childhood • Non-neoplastic complications of infection/immunodeficiency-

related lymphoproliferative disorders (e.g. hemophagocytic lymphohistiocytosis, macrophage activation syndrome)

Lymphoproliferative disorders related to autoimmunity, non-transplant iatrogenic conditions and aging • Autoimmune conditions including systemic lupus erythematosus,

rheumatoid arthritis, and IgG4-related systemic sclerosing disease• Manifestations related to drugs (e.g. methotrexate) or biologic response

modifiers (e.g. interferon, TNF-alpha, G-CSF, monoclonal antibodies)• Other predisposing conditions (e.g. breast implants/seroma, lymphoma)• Aging and immune senescence (e.g. EBV+ lymphoproliferations of the

elderly)

Registration Now Open

www.ascp.org/2015SHmeeting

Featured Guest Speakers & Topics

Mark Davis, PhD Human Immune Senescence: Insights into Immunodeficiency of Aging

Stefania Pittaluga, MD, PhD Primary Immunodeficiency Disorders

Steven Swerdlow, MD Posttransplant Lymphoproliferative Disorders

Ethel Cesarman, MD, PhD Human Oncogenic Herpesviruses

John K. Chan, MD IgG4-Related Systemic Sclerosing Disorders

Scott Boyd, MD, PhD High-Throughput DNA Sequencing Studies of Lymphocyte Repertoires in Inherited and Acquired Immunodeficiency

Katherine Yudeh King, MD, PhD Inflammation Regulates Hematopoietic Stem Cell Function

Robert H. Schiestl, Ph.D. Intestinal microbiota involved in genetic instability, genotoxicity, latency of lymphoma and longevity in Atm deficient mice


WEDNESDAY, OCTOBER 28TH - ASCP/SH DAY AT ASCP 2015

6:30am – 6:00pm Registration at Long Beach Convention Center Open8:00am – 9:30am ASCP Educational Sessions9:45am – 11:15am ASCP Educational Sessions (Including a 90 minute program on The Diagnosis,

Classification and Clinical Care of Peripheral T‐cell Lymphoma (PTCL))1:00pm – 4:10pm ASCP Educational Sessions (Including a 3-hour program on

The Spectrum of Non-Neoplastic Hematologic Disease)4:30pm Poster Presentation Viewing5:00pm – 6:30pm ASCP Grand Opening General Session6:15pm – 8:00pm ASCP Grand Opening Reception in Science Connection Central

THURSDAY, OCTOBER 29TH - SH-EAHP PROGRAM BEGINS

6:30am – 6:00pm Registration at Long Beach Convention Center Open7:00am – 7:50am Continental breakfast for SH attendees7:50am – 8:00 am Welcome and Opening Remarks8:00am – 10:40am SH Workshop Sessions10:40am – 11:00am Break/Networking11:00am – 11:50am SH Workshop Sessions11:50am – 1:00pm Lunch (included) & Networking1:00pm – 5:10pm SH Workshop Sessions5:10pm SH program ends for the day (Dinner on your own)5:30pm – 6:30pm ASCP Exhibitor Attendee Mixer (Reception in Hall)6:40pm – 8:10pm ASCP Educational Sessions6:40pm – 8:30pm ASCP Poster Platform Oral Abstract Sessions

FRIDAY, OCTOBER 30TH - SH-EAHP PROGRAM CONTINUES

6:30am – 12:00pm Registration open at Long Beach Convention Center Open7:00am – 8:00am Continental breakfast for SH attendees8:00am – 10:40am SH Workshop Sessions10:40am–11:00am Break/Networking11:00am – 11:50am SH Workshop Sessions12:00pm – 1:30pm Roche/Ventana Lunch Symposium: Biomarkers of Immune System-Update1:00pm – 5:30pm SH Workshop Sessions6:30pm – 10:30pm SH Halloween Gala Dinner Reception (Costumes highly encouraged!)

SATURDAY, OCTOBER 31ST - SH-EAHP PROGRAM CONCLUDES

7:00am – 8:00am Continental breakfast for SH attendees8:00am – 10:40am SH Workshop Sessions10:40am – 11:00am Break/Networking11:00am – 12:00pm SH Workshop Sessions12:00pm – 12:10pm Closing remarks, meeting ends

Specific SH topics and

speakers with times will be updated in

the Summer

ScheduleNEW – Join us 1 day early for ASCP/SH Day! For only $199 additional, get full access to all of ASCP 2015, includ-ing ASCP/SH day on Wednesday, featuring a full day of hematopathology content presented by both organizations.


Registration InformationThe American Society for Clinical Pathology - ASCP, see www.ascp.org, is managing and hosting the SH/EAHP 2015 Workshop in association with the ASCP 2015 Annual Meeting. ASCP is providing an option to add-on access to the ASCP program for activities outside of SH Workshop times.

For more information about any aspect of the SH/EAHP 2015 Workshop, please contact Jennifer Clark, SCT(ASCP)CMMBCM at 1.312.541.4999 x3901 or by email at [email protected]

Early registration pricing is available until 8/31/2015. Advance registration is encouraged.

The full conference registration fee includes the tuition, conference materials, breaks, lunches, and one gala dinner. Guests may be added to the gala dinner for an additional fee.

There are three ways to register for the workshop:1. Online registration at www.ascp.org/services/Organization/

OrgMeetingInfo?Org=SH is preferred. You will receive immediate email receipt confirmation.

2. Mail to: The Society for Hematopathology, C/O ASCP, 3462 Eagle Way, Chicago, IL 60678

3. Call ASCP Customer Service at: 1.800.267.2727 (Toll-free) 312.541.4848 (International Customer Service) Fax 312.541.4472

We accept the following forms of payment:

• Check (payable through U.S. banks only)• Money Order• Credit Cards (MasterCard, VISA, and American Express)

Refund/Cancellation PolicyA full refund will be issued for cancellations received in writing no later than October 10, 2015. Refunds are not issued for cancellations after this date. ASCP reserves the right to cancel a program due to circumstances beyond its control or for insufficient registration. Registrants will be notified immediately and allowed to substitute a session or obtain a full refund. The Society is not responsible for penalties incurred as a result of cancelled transportation. Please notify us in advance by contacting ASCP Customer Service at 800.267.2727, option 2; international callers: 312.541.4890; or www.ascp.org/feedback.

Registration Open

www.ascp.org/2015SHmeeting


Airports & Ground TransportationLong Beach area is served by two main airports

• John Wayne, Orange County Airport, Santa Ana/ Anaheim (22mi/30minutes from Long Beach)

• LAX Los Angeles International Airport, Los Angeles (23mi/40minutes)

Taxicabs and Shuttle Transportation to the Westin Hotel Long Beach can be arranged upon arrival at either airport

Meeting FacilityThe SH-EAHP 2015 Workshop will be held Thursday – Saturday, October 29-31, 2015 in Long Beach, California, USA at the Long Beach Convention & Entertainment Center. See www.visitlongbeach.com.

The ASCP Annual meeting will also be held at this location from Wednesday – Friday this same week.

AccommodationsThe host hotel for the 2015 SH//EAHP Workshop is the WESTIN Long Beach. The Westin Long Beach is located at 333 East Ocean Blvd in Long Beach, California. See www.westinlongbeachhotel.com.

It is conveniently located halfway between Los Angeles International Airport and Orange County Airport. Only a mile from the beach, and a few minutes from the new Aquarium of the Pacific, guests can experience the best of California.

Room ReservationWe have secured a room block to accommodate our SH/EAHP guests. It is very important that you stay at the WESTIN to receive the preferential pricing we have secured. The Westin hotel group rate pricing will be available until October 8, 2015, so please book early to assure your reservation using the link on the Workshop website.

Reception & DinnerA Gala Reception and Halloween themed dinner will be held at the Westin Long Beach SH/EAHP host hotel on Friday evening, October 30, 2015.

One ticket to this event is complimentary with your workshop registration.

Guests may be added at the cost of $125 each.

Workshop WebsitePlease continue to visit the SH/EAHP 2015 Workshop website at www.ascp.org/2015shmeeting for continuously updated information about this meeting, including information about: Educational program; registration; conference faculty; hotel and gala dinner.

6:30pm - 7:30 pm Cocktails

7:30pm - 9:00 pm Dinner

9:00pm - 10:00 pm Dancing


PARTICIPANT INFORMATIONLast Name First MI

Highest Degree

Department (include box no.)

Specialty

Physician

Institution

Street

City State Zip or Mail Code

E–mail Address

Daytime Phone (with area code) Cell Phone (with area code)

Fax (with area code) Emergency Contact Phone (with area code)

PAYMENT INFORMATIONCharge the following: VISA MasterCard American ExpressCredit Card Number Expiration Date

Credit Card Holder Name (First/Last)

Credit Card Holder Billing Address

IDT Approver Name (First/Last)

IDT Approver E–mail

Authorized Signature (REQUIRED)

2015 Workshop Registration – October 29-31, 2015This is not a self-mailer

Address to:The Society for HematopathologyC/O ASCP3462 Eagle WayChicago, IL 60678

Make check or money order payable to:The Society for Hematopathology

Registration FeesSH/EAHP Members

$649 Rate until 8/31/15 $699 Rate on or after 9/1/15

Non–Members $699 Rate until 8/31/15 $749 Rate on or after 9/1/15

Trainees $449 Rate until 8/31/15 $499 Rate on or after 9/1/15

Dinner Guest FeeGuests for Gala Reception and Dinner

$125 per Guest # of Guests

ASCP/SH Day – Wed, October 28 (New!)For only $199 additional, get full access to ASCP 2015, also located at the Long Beach Convention Center. Includes access to ASCP/SH Day on Wednesday, October 28, featuring a full day of hematopathology sessions, including:

• The Spectrum of Non-Neoplastic Hematologic Disease: Important Non-Malignant Conditions in Lymph Nodes, Bone Marrow, and Flow Cytometry

• The Diagnosis, Classification and Clinical Care of MDS II• The Diagnosis, Classification and Clinical Care of T-Cell Lymphoma

TOTAL Payment

$

ASCP 2015 RegistrationIncludes access to ASCP/SH Day and all ASCP 2015 ses-sions, keynotes, exhibits, and the Opening Reception.

$199

2015 workshop immunodeficiency and...

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