2015 physician referral guide
TRANSCRIPT
UH NEUROLOGICAL INSTITUTE
2015PHYSICIAN REFERRAL GUIDE
University Hospitals Case Medical Center is the primary affiliate of Case Western Reserve University School of Medicine
UHhospitals.org/Neuro • UH Neurological Institute | 32 | University Hospitals • 216-844-2724
Through a dedicated multidisciplinary team of skilled specialists
with access to leading-edge technologies, facilities and
research, the institute delivers premier care for the full range
of neurological disorders. From minor management of
common disorders to the most advanced treatments
and surgeries, no case is too complex.
University Hospitals neuroscience specialists are available to
you as a resource for second opinions or to consult or operate
on complex diseases. By referring patients into the University
Hospitals Neurological Institute, you can count on unparalleled
communication keeping you informed on your patients’
progress, and returning them to your practice for ongoing
care and follow-up. With personalized treatment plans from
specialists in any of our 15 Centers of Excellence, patients may
also receive care from our nationally recognized colleagues at
University Hospitals Rainbow Babies & Children’s Hospital and
University Hospitals Seidman Cancer Center.
Centers of Excellence Include:Brain Health & Memory . . . . . . . . . . . . . . . . . . . . . . . . . 7
Brain Tumor & Neuro-Oncology . . . . . . . . . . . . . . . . . . 10
Community Neurology . . . . . . . . . . . . . . . . . . . . . . . . 16
Comprehensive Stroke . . . . . . . . . . . . . . . . . . . . . . . . 18
Epilepsy . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 22
Functional & Restorative Neurosurgery . . . . . . . . . . . . 26
Music & Medicine . . . . . . . . . . . . . . . . . . . . . . . . . . . . 28
Neurocritical Care . . . . . . . . . . . . . . . . . . . . . . . . . . . . 30
Neurological & Behavioral Outcomes . . . . . . . . . . . . . . 32
Neuromuscular . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 33
Neuropsychiatry . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 36
Neuroscience Nursing Practice . . . . . . . . . . . . . . . . . . . 39
Parkinson’s & Movement Disorders . . . . . . . . . . . . . . . 40
Spinal Neurosurgery . . . . . . . . . . . . . . . . . . . . . . . . . . 42
Traumatic Brain Injury . . . . . . . . . . . . . . . . . . . . . . . . . 44
Recognized by U.S. News & World Report
as one of the nation’s finest neuroscience
programs, University Hospitals
Neurological Institute is Northeast Ohio’s
first designated neurological institute
providing integrated and comprehensive
care for patients with diseases affecting
the nervous system. The institute
comprises 15 Centers of Excellence,
which bring together some of the
country’s foremost experts in neurology,
neurosurgery, neuroradiology,
neuro-oncology, neuro-ophthalmology,
neurotology, neuropathology,
neuropsychology, neuropsychiatry
and related specialties.
Adult Neurology and Neurosurgery ReferralsTo refer an adult patient, please call 216-844-2724
24/7 Transfers and Urgent ConsultationsFor quick, efficient transfers and 24/7 consultation with attending physicians, please call the UH Transfer Referral Center at 216-844-1111 or 1-800-421-9199
Physician Advice LineFor free advice from our nationally renowned neurosurgery specialists, please call 216-844-1001
Immediate Access AvailableThe UH Neurological Institute offers triage services and same-day/next-day availability for patients with urgent needs. When you call 216-844-2724 to refer a patient, please identify the level of urgency so that we can best accommodate you and your patient.
Same-Day EMG ServicesTo schedule a same-day EMG, please call 216-844-1923
Urgent Access or Concerns with Neurology and Neurosurgery Access8 a.m. – 5 p.m. M – F
Tracy Grushcrow Office: 216-844-3418Interim Practice Manager Page: 32393
All Other Times for Neurosurgery Access
Warren Selman, MD Office: 216-844-5745Chairman Page: 35047 Cell: 216-308-3035
Nicholas Bambakidis, MD Office: 216-844-8758Vice Chair Clinical Affairs Page: 37758 Cell: 216-339-4061
Pediatric Neurosurgery ReferralsTo refer a pediatric patient, please call 216-844-PEDS (216-844-7337)
Pediatric Advice LineFor advice from our leading pediatric specialists, please call 216-UH4-ADOC (216-844-2362)
PHYSICIAN RESOURCES
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Warren R. Selman, MDDirector, UH Neurological InstituteChairman, Department of Neurological Surgery Chief of Division of Pediatric Neurosurgery, UH Rainbow Babies & Children’s HospitalOffice Phone: 216-844-5745Appointment Phone: 216-844-2724
Anthony J. Furlan, MDCo-Director, UH Neurological InstituteChairman, Department of Neurology Office Phone: 216-844-3193Appointment Phone: 216-844-2724
Rebecca Kahl, MBAInterim Director, Neurological InstituteOffice Phone: 216-844-8598
Michael A. DeGeorgia, MDDirector, Music & Medicine and Neurocritical Care Centers Office Phone: 216-844-1552Appointment Phone: 216-844-2724
Seth Alan Hoffer, MDDirector, Traumatic Brain Injury CenterOffice Phone: 216-844-5744Appointment Phone: 216-844-2724
Bashar Katirji, MDDirector, Neuromuscular Center Office Phone: 216-844-4854Appointment Phone: 216-844-2724
Alan J. Lerner, MDDirector, Brain Health & Memory Center Office Phone: 216-464-6412Appointment Phone: 216-464-6445
Samden Lhatoo, MDDirector, Epilepsy CenterOffice Phone: 216-844-5855Appointment Phone: 216-844-2724
Joseph A. Locala, MDDirector, Neuropsychiatry CenterOffice Phone: 216-844-2400Appointment Phone: 216-844-2400
Jonathan Miller, MDDirector, Functional & Restorative Neurosurgery CenterOffice Phone: 216-844-3470
Robert J. Ronis, MD, MPHAssociate Director, UH Neurological InstituteChairman, Department of Psychiatry Office Phone: 216-844-3883Appointment Phone: 216-844-3883
Martha Sajatovic, MDDirector, Neurological & Behavioral Outcomes Center Office Phone: 216-368-7572, 216-844-2808Appointment Phone: 216-844-2400
Cathy A. Sila, MDDirector, Comprehensive Stroke Center Office Phone: 216-844-8934Appointment Phone: 216-844-2724
Andrew E. Sloan, MDDirector, Brain Tumor & Neuro-Oncology Center Office Phone: 216-844-6054Appointment Phone: 216-844-2724
Erin Supan, RNDirector, Neuroscience Nursing Practice Center Office Phone: 216-844-2413
Robert W. Tarr, MDAssociate Director, UH Neurological InstituteSection Chief, Department of Neuroradiology Office Phone: 216-844-5722
Benjamin Walter, MDDirector, Parkinson’s & Movement Disorders Center Office Phone: 216-844-8285Appointment Phone: 216-844-2724
LEADERSHIP
UH Case Medical Center is internationally renowned for its
innovations in healing and discovery. In addition to providing
state-of-the-art care for patients with neurological diseases,
the UH Neurological Institute educates medical students,
neurology residents and fellows in neurology subspecialties.
Nationally RecognizedThe University Hospitals Neurological Institute is nationally recognized as one of the premier neuroscience and neurosurgery programs in the country.
In 2014, U.S. News & World Report ranked UH Case Medical Center as one of the nation’s best neurology and neurosurgery programs.
Additionally, after studying multidisciplinary institutes at academic medical centers to describe their operations and assess their impact on performance, University HealthSystem Consortium (UHC) proclaimed the UH Neurological Institute model as the industry benchmark, calling it “a model of interdepartmental collaboration, enhancing value across the clinical, educational and research missions.”
Leading Innovations:• First in the world to test the diaphragm pacing stimulation system
on patients with amyotrophic lateral sclerosis (ALS)• First in North America to perform deep brain stimulation of the
thalamus to successfully treat symptoms of Tourette’s syndrome• One of only six hospital centers in the world experienced in using
AutoLITT for minimally invasive brain tumor surgery• First in Ohio to offer both Gamma Knife® and CyberKnife® in our
Stereotactic Radiosurgery suite• Neuroscience Intensive Care Unit is one of only 25 centers in the
nation offering fellowships in neurocritical care• One of Ohio’s first physician-led Brain Attack programs –
now one of the largest in the nation with 24/7 availability for emergency transfers
• One of only 25 centers in the United States offering surgical therapy for dystonia
• First comprehensive pediatric autonomic lab in the country• Only program in the United States that offers multiple
hippocampal transections for the treatment of epilepsy
National Recognitions:• UH Neurological Institute: Received the Gold Center of Excellence
recognition from NeuStrategy, Inc. for spine, neurovascular stroke, cranial tumor and neuromodulation neurosurgery.
• UH Case Medical Center: Recognized by Becker’s Hospital Review as one of the 100 Top Neurosurgery and Spine programs.
• UH Case Medical Center: Awarded Comprehensive Stroke Center Certification. This is the highest available designation from The Joint Commission.
• Certified Primary Stroke Center: Awarded to UH Ahuja Medical Center, UH Geauga Medical Center, UH Bedford and Richmond Medical Centers, campuses of UH Regional Hospitals, UH Parma Medical Center, St. John Medical Center and Southwest General Health Center.
• Epilepsy Center: Designated as a Level IV Epilepsy Center – the highest designation available – by the National Association of Epilepsy Centers. The Epilepsy Center also received accreditation for both its epilepsy and clinical neurophysiology fellowships.
• Annual Performance Achievement Award for Stroke: Awarded by the American Heart Association
• University Hospitals Case Medical Center, the only major teaching hospital in Ohio to be recognized by Thomson Reuters 100 Top Hospitals
• Beacon Award for Critical Care Excellence• Leapfrog Top 50 Hospitals• Magnet Status for Nursing
INNOVATIONS IN CARING
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Novel ResearchThe commitment to exceptional patient care begins with revolutionary discovery. University Hospitals Case Medical Center is the primary affiliate of Case Western Reserve University School of Medicine, a national leader in medical research and education and consistently ranked among the top research medical schools in the country by U.S. News & World Report. Through their faculty appointments at Case Western Reserve University School of Medicine, physicians at UH Case Medical Center are advancing medical care through innovative clinical research and discovery that bring the latest treatment options to patients.
University Hospitals Case Medical Center and the UH Neurological Institute offer a depth of care and scope of services that no other medical center in Ohio can deliver. As the primary affiliate of Case Western Reserve University School of Medicine, University Hospitals Case Medical Center has unparalleled access to top talent, emerging technologies and therapies, and unequaled clinical research resources.
All National Institutes of Health funding for basic and clinical research is awarded to the School of Medicine at Case Western Reserve University.
Physician Advice LineYou’re just one phone call away from some of the finest neurological specialists and surgeons in the country. Receive immediate decision-making advice from the UH Neurological Institute team of experts by calling 216-844-1001.
Physician CommunicationThe model for interaction with physicians who refer to the UH Neurological Institute emphasizes communication and mutual respect. We ensure continuity of care from referring physician to specialist by providing prompt communication after each patient visit and carefully coordinated perioperative management. To refer a patient, call 216-844-2724.
24-Hour Rapid ReferralCall 216-844-2724 and your patient will be scheduled within 24 hours for an appointment with one of our neurological specialists.
BRAIN HEALTH & MEMORY CENTER
UH Neurological Institute’s Brain Health & Memory
Center has internationally recognized experts who devote
themselves to caring not only for patients, but their families
too. Through an interdisciplinary and longitudinal approach,
treatment processes help maintain cognitive, physical
and emotional fitness, as well as a measure of stability
and reassurance. Programs for community and caregiver
education, quality of care giving and risk factors for memory
loss have been a center priority.
Conditions treated:• Alzheimer’s disease
• Mild cognitive impairment
• Frontotemporal dementia
• Parkinson’s disease dementia
• Dementia with Lewy bodies
• Adult Attention Deficit-Hyperactivity Disorder
• Trisomy 21 (Down syndrome)
• Vascular dementia
• Normal pressure hydrocephalus
• Huntington’s disease
• Creutzfeldt-Jakob disease
InnovationsThe Brain Health & Memory Center has established an interdisciplinary care model that has been adopted by neurological institutes nationwide. It has been a leader for research in Alzheimer’s disease and has contributed to studies of the natural history, genetics and behavioral aspects of Alzheimer’s disease.
Surgical solutions:• Ventriculo-Peritoneal Shunting – For individuals diagnosed with
normal pressure hydrocephalus.
Patients and their families benefit from staff expertise and resources in the following areas:
• Neurology • Pharmacy
• Geriatrics • Neuropsychiatry
• Social work • Neuropsychology
• Pathology • Geropsychiatry
• Nursing • Speech Pathology
• Radiology
Current clinical trialsOver the past two decades, our physicians have emerged as leaders in Alzheimer’s disease evaluation and genetic studies. Clinical trials are ongoing to determine the safety and efficacy of pharmaceutical alternatives, including:
Studies change frequently; the following are those we are currently recruiting for:
• The Alzheimer’s Disease Neuroimaging Initiative (ADNI). The purpose of this study is to build upon the information obtained in the original Alzheimer’s Disease Neuroimaging Initiative (ADNI1) and ADNI-GO (Grand Opportunity; a study funded through an NIH grant under the American Recovery and Reinvestment Act), to examine how brain imaging technology can be used with other tests to measure the progression of mild cognitive impairment (MCI) and early Alzheimer’s disease (AD). ADNI2 seeks to inform the neuroscience of AD. This information will aid in the early detection of AD, and in measuring the effectiveness of treatments in future clinical trials.
• Cataract removal and Alzheimer’s disease. The investigators have designed this study to determine whether or not cataract removal will improve the AD patient’s quality of life, vision and cognition.
• A Phase III double-blind, placebo-controlled, randomized, parallel group, 12-month safety and efficacy trial of Leuco-methylthioninium bis (hydromethanesulfonate) in subjects with Behavioral Variant Frontotemporal Dementia (bvFTD). This multinational study is currently open for enrollment. The primary object is to demonstrate the efficacy of LMTM as assessed by change from baseline on the Addenbrooke’s Cognitive Examination Revised (ACE-R) and the Modified Alzheimer’s Disease Cooperative Study – Clinical Global Impression of Change (Modified ADCS-CGIC) – independently rated.
• The A4 (Anti-Amyloid Treatment in Asymptomatic Alzheimer’s) Study. This will test whether the amyloid antibody called solanezumab can prevent or slow the progression of Alzheimer’s disease. Amyloid is a protein normally produced in the brain that can build up in older people, forming amyloid plaque deposits. Scientists believe this buildup of deposits may play a key role in the eventual development of Alzheimer’s disease-related memory loss. The A4 study will enroll older adults, age 65 to 85, who have normal thinking and memory function. Participants will be screened to determine if they have elevated levels of amyloid plaques in their brains detected through a PET imaging scan. The overall goal of the A4 study is to test whether decreasing amyloid in the brain can help slow the memory loss associated with amyloid buildup.
INNOVATIONS IN CARING
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BRAIN HEALTH & MEMORY CENTER
For a current list of clinical trials within the Brain Health & Memory Center, visit UHhospitals.org/trials/neuro/clinicaltrials.
• Longitudinal Evaluation of Amyloid Risk and Neurodegeneration (LEARN) Study. A companion study to Anti-Amyloid Treatment in Asymptomatic Alzheimer’s Disease (A4) Trial. This is a multicenter, observational study evaluating the rate of cognitive change in approximately 500 subjects without evidence of elevated Aß on screening PET scan. To characterize the longitudinal change on the cognitive, clinical and biomarker measures used in the A4 trial in Aßne individuals in comparison to the Aße A4 placebo arm individuals.
• Study of Nasal Insulin to Fight Forgetfulness (SNIFF). An 18-month clinical trial testing nasal insulin to treat early Alzheimer’s disease is at 30 research sites nationwide. The nasal insulin approach has shown promise in previous short-term clinical trials. It is hypothesized that after 12 months of treatment with intranasally administered insulin compared to placebo, participants will improve cognition, memory and daily function.
• The NOBLE study is a Phase-2 multicenter, randomized, double blind, placebo-controlled, parallel group study that will explore the potential of the investigational drug T-817MA, a neuroprotectant agent designed to protect against neuron loss. Neuroprotectants are used for many central nervous system disorders including stroke and Parkinson’s disease. The study will enroll 450 people with mild-to-moderate AD at research sites across the United States. Eligible candidates include women and men aged 55 to 85 years old with mild-to-moderate AD who have been taking donepezil (Aricept®) for at least six months prior to enrollment. The duration of treatment is about 14 months. The potential of T-817MA to modify the pace of the disease may positively impact quality of life in those who are currently suffering with mild-to-moderate AD as well as their caregivers. The study is sponsored by Toyama Chemical Co., Ltd, FUJIFILM Group, and is being conducted by the Alzheimer’s Disease Cooperative Study (ADCS).
• Apathy in Dementia Methylphenidate Trial 2 (ADMET 2) is a Phase III, placebo-controlled, masked, six-month, 10-center randomized clinical trial sponsored by the National Institute of Aging involving 200 participants with Alzheimer’s disease. ADMET 2 is designed to examine the efficacy and safety of methylphenidate as treatment for clinically significant apathy in AD participants. ADMET 2 will enroll participants from real-world settings such as outpatient, nursing home and assisted-living facilities and will examine the effects of methylphenidate on apathy and cognition. ADMET 2 will also conduct careful safety monitoring.
ProgramsOur center coordinates with primary care physicians to go beyond treating biological issues by offering specialty services, such as:
• Alzheimer’s Disease & Memory Disorders Program: Evaluates and treats individuals with Alzheimer’s disease and related dementia syndromes. Services include traditional medical treatments and state-of-the-art clinical research programs.
• Memory Health Program: Targets individuals with concerns about maintaining brain health. The program offers a variety of services related to maintaining cognitive wellness in the context of aging.
• Sports Concussion Program: Evaluation of the severity and consequences of sports concussion in athletes, including assessment of safety for return to play and indicators of prognosis from head injury.
• Huntington’s Disease Interdisciplinary Clinic: Offers neurology, psychiatry, social work and genetics evaluation to patients and their families. Prescreening examinations to patients’ adult family members are also available.
• Prion Disease Program: Prion diseases are a group of rapidly progressive neurodegenerative conditions that are caused by an abnormal form of the prion protein. Sporadic Creutzfeldt-Jakob disease (sCJD) is the most common prion disease and is caused by a spontaneous change in the normal prion protein. UH physician Brian Appleby, MD, serves as Co-Director of the National Prion Disease Pathology Surveillance Center and is a Member of the CJD Foundation’s Board of Directors, and his primary research and clinical interest is prion disease.
Alan J. Lerner, MDOffice Phone: 216-464-6412Appointment Phone: 216-464-6445
Special Interests: Alzheimer’s Disease, Dementia, Behavioral Neurology, General Neurology, Higher Cortical Functions, Adult Attention Deficit Disorder (adult ADD/ADHD), Frontotemporal Dementia
Sees Patients at: UH Ahuja Medical Center, UH Foley ElderHealth Center
Brian Appleby, MDOffice Phone: 216-464-6445Appointment Phone: 216-844-2724
Special Interests: Neurology, Psychiatry, Geriatric Psychiatry, Atypical Dementia, Creutzfeldt-Jakob Disease and Frontotemporal Dementia
Sees Patients at: UH Foley ElderHealth Center
Christopher Bailey, PhDOffice Phone: 216-844-3422Appointment Phone: 216-844-2724
Special Interests: Adult/Geriatric Neuropsychology, Alzheimer’s Disease, Attention-Deficit/Hyperactivity Disorder (ADD/ADHD), Concussion, Dementia, Disability/Legal, Deep Brain Stimulation Surgery, Epilepsy and Epilepsy Surgery, Forensic Neuropsychology, Hydrocephalus, Memory Loss, Mild Cognitive Impairment, Neuropsychological Independent Medical Exam, Traumatic Brain Injury (TBI)
Sees Patients at: UH Case Medical Center, UH Ahuja Medical Center
Suzanne Debrosse, MDOffice Phone: 216-844-3936Appointment Phone: 1-866-UH4-CARE
Special Interests: Pediatric Genetics, Genetics
Sees Patients at: UH Case Medical Center
Philip Fastenau, PhDOffice Phone: 216-844-3422Appointment Phone: 216-844-2724
Special Interests: Alzheimer’s Disease, Attention-Deficit/Hyperactivity Disorder (ADD/ADHD), Concussion, Deep Brain Stimulation Surgery, Dementia, Epilepsy and Epilepsy Surgery, Hydrocephalus, Learning Disability (LD), Memory Loss, Mild Cognitive Impairment, Neuropsychological Test Development, Pediatric/Adult/Geriatric Neuropsychology, Traumatic Brain Injury (TBI)
Sees Patients at: UH Case Medical Center,UH Westlake Health Center
Cynthia Griggins, PhDOffice Phone: 216-844-1852Appointment Phone: 216-844-2724
Special Interests: ADHD and Learning Disabilities in Adults, Chronic Medical Conditions, Clinical Ethics, Cognitive Rehabilitation, Counseling and Therapy for Neurological Disorders, Dementia, Head Injury, Higher Cortical Functions, Language Mapping, Neuroethics, Neuropsychological Assessment of Adults and Adolescents, Stroke
Sees Patients at: UH Case Medical Center
Steven A. Gunzler, MDOffice Phone: 216-844-8685Appointment Phone: 216-844-2724
Special Interests: Ataxia, Neurology, Dystonia, Memory and Aging, Botulinum Toxin Injections, Movement Disorders, Dementia, Parkinson’s Disease, Huntington’s Disease, Tremors
Sees Patients at: UH Ahuja Medical Center, UH University Suburban Health Center, UH Foley ElderHealth Center
James Mack, PhDOffice Phone: 216-844-3188
Special Interest: Neuropsychiatry
Sees Patients at: UH Rehabilitation Hospital
Paula K. Ogrocki, PhDOffice Phone: 216-464-6412Appointment Phone: 216-464-6445
Special Interests: Alzheimer’s Disease & Dementia, Geriatric Neuro-Psychology, Memory and Aging, Licensed Clinical Psychologist, Forgetfulness, Psychological Testing
Sees Patients at: UH Ahuja Medical Center
BRAIN HEALTH & MEMORY CENTER
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UH Neurological Institute’s Brain Tumor & Neuro-Oncology
Center facilitates seamless collaborations between
University Hospitals world-renowned main campus facilities,
UH Seidman Cancer Center and UH Rainbow Babies &
Children’s Hospital to treat adult and pediatric patients
with both benign and malignant tumors. The interdisciplinary
approach enables UH Case Medical Center to offer a
personalized treatment plan for each patient and their
referring physician, while simultaneously giving them access
to top experts in the field and the most advanced clinical
trials available.
Surgical solutions:• Laser Interstitial Thermotherapy (NeuroBlate® System) in the
intraoperative MRI
• Gamma Knife® and CyberKnife® Radiosurgery for brain and spine tumors
• Image-guided surgical navigation
• Intraoperative magnetic resonance imaging operating room
• Intraoperative brain mapping of tumor and functionally critical brain involving motor, language, sensory, visual and cranial nerves
• Endoscopic neurosurgical techniques
• Multidisciplinary skull-base approaches
Minimally invasive and nonsurgical solutions:• Laser Interstitial Thermotherapy (NeuroBlate® System) in the
intraoperative MRI
• Gamma Knife® Radiosurgery
• CyberKnife® Radiosurgery
Conditions treatedThe Brain Tumor & Neuro-Oncology Center treats adult and pediatric patients with both benign and malignant tumors, including:
• Acoustic neuromas
• Astrocytomas
• Brain stem gliomas
• Ependymomas
• Glioblastomas
• Gliomas
• Medulloblastomas
• Meningiomas
• Mixed gliomas
• Neurofibromatosis 1 & 2
• Oligoastrocytomas
• Oligodendrogliomas
• Optic nerve gliomas
• Pilocytic Astrocytomas
• Skull-base tumors
Laser Interstitial Thermotherapy in the intraoperative MRI
UH Case Medical Center was one of two hospitals to help Monteris Medical, Inc. pioneer the NeuroBlate® System. This new technology enables the surgeon to use MRI-guided lasers to destroy previously
inoperable tumors without damaging the surrounding healthy tissue. This revolutionary technology and minimally invasive
approach is especially effective in treating glioblastoma, one of the most aggressive and difficult-to-treat brain cancers. UH Case
Medical Center is one of only nine hospital centers in the United States using this technology.
BRAIN TUMOR & NEURO-ONCOLOGY CENTER
InnovationsSurgeons at UH are pioneering new approaches of minimally invasive brain surgery including:
• Laser Interstitial Thermotherapy with real-time MRI using the Monteris NeuroBlate® System
• Brain mapping with functional MRI (fMRI), Diffusion Tensor Imaging (DTI) and/or magnetoencephalography (MEG) to optimize identification of brain tumors and surrounding normal tissues
• Intraoperative MRI to maximize safety and completeness of tumor removal
• New techniques for optical and fluorescence imaging to better identify infiltrating tumor
• Convection Enhanced Delivery (CED): A technology to improve delivery of small anti-tumor molecules and chemotherapy to brain tumors
• Stereotactic Radiosurgery using Gamma Knife® or CyberKnife®
Current clinical trials:• 06-benzylguanine (BG) and Temozolomide (TMZ) Therapy
of Glioblastoma Multiforme (GBM) in Patients with MGMT Positive Tumors with Infusion of Autologous P140KMGMT+ Hematopoietic Progenitors to Protect Hematopoiesis
• Fluorescence-Guided Detection of Malignant Gliomas: A Dose Ranging Study Using 5-Aminolevulinic Acid (ALA) Induced Protoporphyrin (PpIX) in a Multicenter Phase II Clinical Trial
• A Phase II Clinical Trial Evaluating DCVax-Brain, Autologous Dendritic Cells Pulsed with Tumor Lysate Antigen for the Treatment of Glioblastoma Multiforme
• A Phase I Study of Methoxyamine and Temozolomide in Patients with Advanced Solid Tumors
• Phase III Study of Radiation Therapy with or without Temozolomide for Symptomatic or Progressive Low-Grade Gliomas
• Phase II Trial of Observation for Low-Risk Meningiomas and of Radiotherapy for Intermediate and High-Risk Meningiomas
Nontherapeutic:• International Case-Control Study of Malignant Glioma
(A GLIOGENE Consortium Site)
• The Cancer Genome Atlas Patient Enrollment and Specimen Qualification Criteria Glioblastoma Multiforme
• Biorepository and Tissue Processing Core Facility
• Ohio Brain Tumor Study
• GLIOGENE: An International Brain Tumor Linkage Consortium Site
All National Institutes of Health funding for basic and clinical research is awarded to the School of Medicine at Case Western Reserve University.
Daily interactions among multidisciplinary team members, combined with the most current treatment protocols, facilitate rapid response to individual therapeutic needs and modifications as necessary.
ProgramsSpecialized programs allow physicians to develop appropriate paths to create personalized treatment plans with specialists from other areas of excellence within UH. Programs include:
• Benign Brain Tumor Program: Incorporates minimally invasive and image-guided approaches, endoscopic, skull base and radiosurgical techniques to treat and often cure benign tumors of the brain.
• Malignant Brain Tumor Program: Offers patients and referring physicians a personalized approach to innovative new therapies including new surgical techniques and technology and advanced therapeutic agents. Surgical trials include minimally invasive laser interstitial therapy with real-time intraoperative MRI, new methods of imaging to improve resection including optical imaging of tumor and intraoperative MRI guided resection.
BRAIN TUMOR & NEURO-ONCOLOGY CENTER
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Other novel therapies include tumor vaccines (immunotherapy), targeting tumor stem cells, use of normal hematopoetic stem cells to minimize chemotherapy induced complications, and advanced chemotherapy in combination with anti-angiogenic approaches through internal trials at UH Case Medical Center, the Case Comprehensive Cancer Center, the Adult Brain Tumor Consortium (ABTC) and the Radiation Therapy and Oncology Group (RTOG).
• Metastatic Brain Tumor Program: Treatment approaches include integration of radiotherapy and radiosurgical approaches with Gamma Knife® and CyberKnife®, as well as advanced surgical techniques, to optimize outcomes and minimize risk.
• Skull Base Surgery Program: A multidisciplinary team of neurosurgeons, head and neck surgeons, otolaryngologists, ophthalmologists and radiation oncologists who use minimally invasive, image-guided and radiosurgical techniques to optimize outcome and minimize risk.
• Pediatric Neuro-oncology: Provides comprehensive, coordinated care through research, clinical care and support services to pediatric patients with brain and spinal tumors and their families. Using an integrated team approach, the center leverages the expertise of its nationally recognized specialists in neurosurgery, neurology, neuro-oncology, oncology, radiation oncology, neuro-pathology, otolaryngology and radiology. The team’s focus on innovation and research ensures that our pediatric patients are among the first to receive groundbreaking treatments and therapies.
• Pituitary/Neuro-Endocrine Program: Multidisciplinary team of neurosurgeons, skull base surgeons, radiation oncologists and endocrinologists employ a team approach to diagnose and treat disease of the pituitary and neuro-endocrine system.
• Spine Tumor Program: Integrated team of radiation oncologists, spinal surgical oncologists, medical oncologists, orthopaedic specialists and rehabilitation specialists focused on diagnosis and treatment of spinal neoplasms.
• Neurofibromatosis 2 Center: The UH Neurofibromatosis 2 Center is comprised of a multidisciplinary group of surgeons and specialists in neurosurgery, neurology, oncology, otolaryngology and genetics. Our team also includes specialists and subspecialists in all related areas, including radiology, ophthalmology and radiation therapy, as well as various supporting services. We offer standard and innovative treatment options including management through medication, radiation or surgery. Hearing rehabilitation using auditory brainstem implants (ABI) or cochlear implantation (when appropriate) also are available. Because NF2 can impact hearing, patients and families may have difficulty coping with this disorder. To help increase their understanding and make them more comfortable, we provide information about treatment options, keep them updated on the patient’s progress and encourage them to ask questions. The goal is to help patients heal both medically and emotionally, and enhance their overall quality of life.
• Treatment of Brain Tumors in the Elderly: Integrated and multidisciplinary approach to tailoring treatments from other programs to accommodate patients over the age of 65.
• Neuro-Oncology Cancer Pain Program: Integrated multidisciplinary approach to treatment of cancer-related pain for patients with brain tumors.
• Stereotactic Radiosurgery: Multidisciplinary team of neurosurgeons, spine surgeons, radiation oncologists, physicists and medical oncologists utilizing state-of-the-art technology Gamma Knife® Perfexion® and CyberKnife® for minimally invasive approaches to the treatment of lesions of the brain and spine.
• Pediatric Neurosurgery: Our expert neurosurgeons are skilled in the latest approaches and use the latest technologies to provide customized surgical solutions to pediatric patients with a wide variety of neurological conditions.
Simon Lo, MD, Radiation Oncologist and Director for Radiosurgery, has helped formulate a new method for precisely determining the dosage used for patients receiving a limited number (one to five) of Gamma Knife® or CyberKnife® treatments. This independently validated approach is safer when used alone or in conjunction with chemotherapy as it minimizes the damage to surrounding tissue and results in more favorable outcomes for our patients.
Specialized equipment:• Laser Interstitial Thermotherapy (LITT) in the intraoperative MRI
• Gamma Knife®
• CyberKnife®
• Intraoperative MRI (iMRI)
CyberKnife®
BRAIN TUMOR & NEURO-ONCOLOGY CENTER
Andrew E. Sloan, MDOffice Phone: 216-844-6054Appointment Phone: 216-844-2724
Special Interests: Convection Enhanced Delivery (CED), Tumor Vaccines (Immunotherapy), Brain Tumors, Skull Base Surgery, Gamma Knife® and CyberKnife® Stereotactic Radiosurgery, Image Guided Neurosurgery, Stereotactic Surgery, Neuro-oncology, Spinal Cord Tumors
Sees Patients at: UH Case Medical Center
Baha Arafah, MDOffice Phone: 216-844-3142Appointment Phone: 216-844-8500
Special Interests: Endocrinology, Pituitary Disorders, Adrenal Disorders
Sees Patients at: UH Case Medical Center
Nicholas C. Bambakidis, MDOffice Phone: 216-844-8758Appointment Phone: 216-844-2724
Special Interests: Neuro-oncology, Spinal Cord Tumors, Skull Base Surgery
Sees Patients at: UH Case Medical Center, UH Ahuja Medical Center
David Bardenstein, MDOffice Phone: 216-844-8686Appointment Phone: 216-844-1700
Special Interests: Ophthalmology, Orbital Disease, Ocular Oncology, Ocular Pathology, Ophthalmic Reconstructive Surgery, Cancer of the Eye, Eye Disease, Eye Pathology, Eye Reconstructive Surgery, Melanoma
Sees Patients at: UH Case Medical Center, UH Landerbrook Health Center, UH Westlake Health Center
Michael Coffey, MDOffice Phone: 216-844-3061Appointment Phone: 216-844-2724
Special Interests: MRI, Neuroradiology
Sees Patients at: UH Case Medical Center
Mark L. Cohen, MDOffice Phone: 216-844-8928
Special Interest: Diagnostic Neuropathology
Sees Patients at: UH Case Medical Center
Peter de Blank, MD, MSOffice Phone: 216-844-3345Appointment Phone: 1-866-UH4-CARE
Special Interests: Pediatric Hematology/Oncology, Pediatrics
Sees Patients at: UH Rainbow Babies & Children’s Hospital
Stanton Gerson, MDOffice Phone: 216-844-8562Appointment Phone: 1-866-UH4-CARE
Special Interests: Hematology, Leukemia, Lymphoma, Malignant Hematology, Myelodysplasia, Myeloma, Oncology, Transplantation
Sees Patients at: UH Case Medical Center, UH Chagrin Highlands Health Center
Joseph Gibbons, MDOffice Phone: 216-844-4735Appointment Phone: 1-866-UH4-CARE
Special Interests: Bone & Soft Tissue Cancer, Breast Cancer, Gastrointestinal Cancer, Genitourinary Cancer, Hematology/Oncology, Sarcoma
Sees Patients at: UH Case Medical Center, UH Chagrin Highlands Health Center, UH Westlake Health Center
Deborah Gold, MDOffice Phone: 216-844-3691Appointment Phone: 216-844-7700
Special Interests: Pediatric Neurology, Neuro-oncology, Pediatric Stroke
Sees Patients at: UH Rainbow Babies & Children’s Hospital, UH Rainbow Specialty Center – Landerbrook, UH Mentor Health Center
Seth Alan Hoffer, MDOffice Phone: 216-844-5744Appointment Phone: 216-844-2724
Special Interest: Spinal Cord Tumors
Sees Patients at: UH Case Medical Center, UH Bedford Medical Center, UH Richmond Medical Center
BRAIN TUMOR & NEURO-ONCOLOGY CENTER
UHhospitals.org/Neuro • UH Neurological Institute | 1514 | University Hospitals • 216-844-2724
Henry B. Koon, MDOffice Phone: 216-844-0120Appointment Phone: 216-844-7700
Special Interests: Hematology/Oncology, Melanoma, Cutaneous Lymphoma, Renal Cell Carcinoma, Immunotherapy, Bone & Soft Tissue Cancer
Sees Patients at: UH Case Medical Center, UH Chagrin Highlands Health Center, UH Westlake Health Center
Charles Lanzieri, MDOffice Phone: 216-844-5721
Special Interests: CNS Imaging, Head and Neck Imaging, Interventional Neuroradiology
Sees Patients at: UH Case Medical Center
Simon Lo, MDOffice Phone: 216-844-3103Appointment Phone: 216-844-2724
Special Interests: Gamma Knife® Radiosurgery, Brain & Spinal Tumors, Stereotactic Body Radiation Therapy, Stereotactic Ablative Radiotherapy, Bone Metastasis
Sees Patients at: UH Case Medical Center
Joseph A. Locala, MDOffice Phone: 216-844-2400Appointment Phone: 216-844-2400
Special Interests: Adult Psychiatry, Psychosomatic Psychiatry, Psychiatric Care of Medically Ill Patients, Transplant Psychiatry, Mood Disorders in the Medically Ill, Anxiety Disorders in the Medically Ill
Sees Patients at: UH Case Medical Center, UH Seidman Cancer Center, W.O. Walker Center
Janice A. Lyons, MDOffice Phone: 216-844-2536Appointment Phone: 216-844-3951
Special Interests: Radiation Oncology, Breast Cancer
Sees Patients at: UH Case Medical Center, UH Chagrin Highlands Health Center, UH Westlake Health Center
Mitchell Machtay, MDOffice Phone: 216-844-2530Appointment Phone: 216-844-3951
Special Interests: Lung Cancer, Head and Neck Cancer, Brain/Spine Tumors, IMRT and Radiosurgery, Bone & Soft Tissue Cancer, Neuro-oncology, Genitourinary Oncology, Gynecologic Cancer, Malignant Hematology, Pediatric Hematology/Oncology
Sees Patients at: UH Case Medical Center
Cliff A. Megerian, MDOffice Phone: 216-844-5500Appointment Phone: 216-844-6000
Special Interests: Hearing Loss, Otitis, Chronic Ear Disease, Surgery for Hearing Loss and Tumor, Vertigo, Meniere’s Disease, Dizziness, Neurotology, Skull Based Surgery, Acoustic Neuromas
Sees Patients at: UH Case Medical Center, UH Chagrin Highlands Health Center, UH Westlake Health Center
Jonathan Miller, MDOffice Phone: 216-844-3470Appointment Phone: 216-844-2724
Special Interests: Cancer Pain, Stereotatic & Functional Neurosurgery, Gamma Knife® Stereotactic Radiosurgery, Neuro-oncology, Spinal Cord Tumors
Sees Patients at: UH Case Medical Center
Charles Nock, MDOffice Phone: 216-844-3682Appointment Phone: 216-844-3951
Special Interests: Melanoma, Genitourinary Malignancies, Neuro-oncology
Sees Patients at: UH Case Medical Center, UH Westlake Health Center
Susan Padrino, MDOffice Phone: 216-844-3400Appointment Phone: 216-844-3400
Special Interests: Adult Psychiatry, Community Psychiatry, Internal Medicine, Resident Education, Medical Student Education, Physical Diagnosis, Direct Observation, Family Therapy, Residency Education
Sees Patients at: UH Case Medical Center, UH Seidman Cancer Center
BRAIN TUMOR & NEURO-ONCOLOGY CENTER
Stefani Parrisbalogun, MDOffice Phone: 216-983-5650Appointment Phone: 216-983-5650
Special Interests: Adult Psychiatry, Psychiatric Care of Medically Ill Patients, Psychosomatic Medicine, Emergency Psychiatry, HIV/AIDS Psychiatry, Bariatric Psychiatry
Sees Patients at: W.O. Walker Center, UH Seidman Cancer Center
Mark Rodgers, MDOffice Phone: 216-844-3478Appointment Phone: 216-844-2724
Special Interest: Anatomic Pathology
Sees Patients at: UH Case Medical Center
Lisa Rogers, DOOffice Phone: 216-844-3717Appointment Phone: 216-844-2724
Special Interests: Neuro-oncology, Brain Tumor, Neurological Complications of Cancer
Sees Patients at: UH Case Medical Center, UH Ahuja Medical Center, UH Chagrin Highlands Health Center
Warren R. Selman, MDOffice Phone: 216-844-5745Appointment Phone: 216-844-2724
Special Interests: Skull Base Tumors, Acoustic Neuromas, Meningiomas, Pituitary Tumors, Spinal Cord Tumors
Sees Patients at: UH Case Medical Center
Binit Shah, MDOffice Phone: 216-844-3771Appointment Phone: 216-844-3771
Special Interests: Psycho-Oncology, Chronic Pain, Pain Rehabilitation
Sees Patients at: UH Case Medical Center, UH Seidman Cancer Center, W.O. Walker Center
Paula Silverman, MDOffice Phone: 216-844-8510Appointment Phone: 216-844-3951
Special Interests: Hematology and Oncology, Breast Cancer
Sees Patients at: UH Case Medical Center, UH Chagrin Highlands Health Center, UH Westlake Health Center
Duncan Stearns, MDOffice Phone: 216-286-7400Appointment Phone: 1-866-UH4-CARE
Special Interests: Pediatric Hematology/Oncology, Pediatrics
Sees Patients at: UH Rainbow Babies & Children’s Hospital
Jeffrey L. Sunshine, MD, PhDOffice Phone: 216-844-3112Appointment Phone: 216-844-3112
Special Interests: Neuroradiology, Interventional Neuroradiology, Head and Neck Imaging, MRI, Acute Stroke Treatment, Brain Aneurysm, Carotid Stenosis, Brain and Spine AVM, Intracranial Stenosis, MR Imaging Head, Neck, Spine
Sees Patients at: UH Case Medical Center
Krystal Tomei, MD, MPHOffice Phone: 216-844-5741Appointment Phone: 216-844-7337
Special Interests: Hydrocephalus, Pediatric Brain Tumors, Congenital Spinal Disorders and Spina Bifida, Tethered Cords, Craniosynostosis, Spasticity, Spinal Deformities, Pediatric Traumatic Brain Injury, Pediatric Spinal Injury
Sees Patients at: UH Rainbow Babies & Children’s Hospital
BRAIN TUMOR & NEURO-ONCOLOGY CENTER
UHhospitals.org/Neuro • UH Neurological Institute | 1716 | University Hospitals • 216-844-2724
At the Community Neurology Center, our experienced
doctors use an interdisciplinary, highly integrated approach
to care for patients with undiagnosed neurological disorders
or those seeking second opinions. Offering appointment
accessibility in many locations throughout the greater
Cleveland area, patients receive a comprehensive
evaluation, treatment, prevention and rehabilitation
services. The programs are led by clinicians who are
recognized and respected for accomplishments in their
respective fields of expertise.
Patients who visit our community facilities receive the same level of clinical expertise and comprehensive range of neurological services available at UH Case Medical Center. The neurologists and neurosurgeons at these locations are supported by the UH Neurological Institute and have unfettered access to its multidisciplinary team of specialists, leading-edge technology and complete range of medical resources.
Conditions treatedThe Community Neurology Center provides comprehensive care for patients with diseases of the nervous system. Conditions treated include:
• Advanced back and spine surgery
• Alzheimer’s and dementia disorders
• Autonomic disorders
• Brain surgery
• Chronic pain
• Epilepsy
• Fibromyalgia
• General neurology conditions and disorders
• Headache (including migraine)
• Multiple sclerosis
• Neuromuscular diseases
• Parkinson’s disease
• Peripheral neuropathy
• Radiculopathy
• Stroke
• And more
Programs:• Headache Management: Diagnose and treat migraine, cluster,
sinus and tension headaches.
• Neuro-ophthalmology: Diagnose and manage treatment for patients experiencing visual disturbances from optic nerve diseases, central nervous system disorders, ocular motility dysfunction and pupillary abnormalities. Patients benefit from collaboration between clinicians and world-renowned investigators in the field of eye movements.
• Multiple Sclerosis: Experienced experts provide early diagnosis and treatment with the latest disease-modifying drugs to positively alter the course of multiple sclerosis.
• Pain Management: Management of neuropathic pain syndromes such as radiculopathies, trigeminal neuralgia, postherpetic neuralgia, phantom limb pain, complex regional pain syndromes and the various peripheral neuropathies.
• Sleep Disorders: Diagnose and manage a variety of sleep disorders including sleep apnea, narcolepsy, restless leg syndrome, insomnia, circadian rhythm disorders and parasomnia.
Specialized equipment:• EEG are recorded in community locations and read by world
renowned epileptologists at UH Case Medical Center.
• EMG tests are performed by registered technologists and physicians with subspecialty training in neuromuscular and electrodiagnostic medicine.
• Autonomic Lab full tests are performed throughout community locations.
COMMUNITY NEUROLOGY CENTER
John Andrefsky, MDOffice Phone: 440-743-8120Appointment Phone: 216-844-2724
Special Interests: General Neurology, Stroke
See Patients at: UH Parma Medical Center
Marek A. Buczek, MDOffice Phone: 440-250-5303Appointment Phone: 216-844-2724
Special Interests: General Neurology, Electrophysiology, Headache, Chronic Pain Syndromes, Head Injury, Language Mapping
Sees Patients at: UH Case Medical Center, UH Westlake Health Center, St. John Medical Center
Michael W. Devereaux, MDOffice Phone: 216-844-3591Appointment Phone: 216-844-2724
Special Interests: Multiple Sclerosis, Epilepsy, General Neurology, Neuro-Ophthalmology
Sees Patients at: UH Case Medical Center, UH Ahuja Medical Center, UH Richmond Medical Center, UH University Suburban Health Center, UH Geneva Medical Center, UH Medina Health Center
Stefan Dupont, MD, PhDOffice Phone: 216-285-5041Appointment Phone: 216-844-2724
Special Interests: Neurology, Vascular Neurology, Stroke
Sees Patients at: UH Ahuja Medical Center
COMMUNITY NEUROLOGY CENTER
Suresh Kumar, MDOffice Phone: 440-816-6794Appointment Phone: 440-816-6794
Special Interest: Neurology
Sees Patients at: UH Parma Medical Center, Southwest General Health Center
Daniel W. Miller, MDOffice Phone: 216-844-7380Appointment Phone: 216-844-2724
Special Interests: General Neurology, Neuromuscular Disorders, Neurophysiology, EMG
Sees Patients at: UH Case Medical Center, UH University Suburban Health Center
Kempsagar Ravishankar, MDOffice Phone: 440-826-9221Appointment Phone: 440-826-9221
Special Interest: Neurology
Sees Patients at: Southwest General Health Center
Mark Rorick, MDOffice Phone: 440-285-2888Appointment Phone: 216-844-2724
Special Interest: General Neurology
Sees Patients at: UH Geauga Medical Center, UH Mentor Health Center
Alessandro Serra, MD, PhDOffice Phone: 216-844-3193Appointment Phone: 216-844-2724
Special Interests: Multiple Sclerosis, Neuroimmunological Disorders
Sees Patients at: UH Case Medical Center, UH Ahuja Medical Center
Tanvir U. Syed, MDOffice Phone: 440-827-5061Appointment Phone: 216-844-2724
Special Interests: Intraoperative Monitoring, Epilepsy, Language Mapping, Higher Cortical Functions, Pseudoseizures, Outcomes Research, Biostatistics, Psychogenic Nonepileptic Seizures
Sees Patients at: UH Westlake Health Center, St. John Medical Center, UH Medina Health Center
Marie Tani, MDOffice Phone: 440-357-3100Appointment Phone: 440-357-3100
Special Interests: General Neurology, Multiple Sclerosis
Sees Patients at: UH Concord Health Center
Colleen B. Tomcik, MDOffice Phone: 440-735-4723Appointment Phone: 216-844-2724
Special Interests: Higher Cortical Functions, Medical Education, Neurology, Headache
Sees Patients at: UH Case Medical Center, UH Ahuja Medical Center, UH Bedford Medical Center, UH Twinsburg Health Center
Mark Walker, MDOffice Phone: 216-286-0315Appointment Phone: 216-286-0315
Special Interests: Vestibular Disorders, Vertigo, Eye Movement Disorders, Nystagmus, Cerebellar Ataxia
Sees Patients at: UH Case Medical Center
Leonard Weinberger, MDOffice Phone: 440-357-3100Appointment Phone: 440-357-3100
Special Interests: General Neurology, Parkinson’s Disease, EMG
Sees Patients at: UH Concord Health Center
Norton A. Winer, MDOffice Phone: 216-383-7850Appointment Phone: 216-383-7850
Special Interests: Sports Related Neurological Injuries, Cerebrovascular Disease, Carotid Ultrasonography, Pain Management
Sees Patients at: UH Richmond Medical Center, UH Mentor Health Center
UHhospitals.org/Neuro • UH Neurological Institute | 1918 | University Hospitals • 216-844-2724
UH Neurological Institute’s Comprehensive Stroke Center
is the premier leader in stroke care in Northeast Ohio.
UH Case Medical Center was the first hospital in
Northeast Ohio to achieve The Joint Commission’s
standards for Comprehensive Stroke Center Certification.
The center also has the most experienced stroke team in Northeast Ohio with a world-class, multidisciplinary team including five board-certified vascular neurologists, four neurointensivists, three interventional neuroradiologists and two cerebrovascular neurosurgeons.
The Joint Commission also has designated UH Ahuja Medical Center, UH Bedford Medical Center, UH Geauga Medical Center, UH Parma Medical Center, UH Richmond Medical Center, St. John Medical Center and Southwest General Health Center as certified Primary Stroke Centers. UH Case Medical Center also meets Brain Attack Coalition criteria for a comprehensive stroke center and has a dedicated stroke inpatient service.
Minimally invasive and nonsurgical solutions:• Treatment of complex vascular malformations deemed
“inoperable” with “knifeless” procedures such as Gamma Knife® and CyberKnife® Stereotactic Radiosurgery
• Experienced team of neuro-interventionalists offering minimally invasive endovascular ablation of aneurysms and AVMs, angioplasty and stenting of extracranial and intracranial stenosis, and emergency treatment of acute stroke or vasospasm
Surgical solutions:• Aneurysm repair, vascular reformations and
diseased-artery bypasses
• Carotid revascularization and EC-IC bypass procedures
Conditions treated:• Diagnosis and management of complex diseases in patients
with vascular disorders of the brain or spine including those considered high-risk due to age, co-morbid conditions or inability to tolerate anesthesia
• Emergent evaluation of transient ischemic attacks and stroke
• Aneurysms
• Arteriovenous malformations (AVMs), dural and cavernous malformations
• Intracranial stenosis
• Carotid artery atherosclerotic stenosis or occlusion
• Stroke due to cardiac disease, including patent foramen ovale (PFO)
• Lacunar or small vessel disease
• Carotid or vertebral artery dissection
• Cerebral vasculitis
• Other unusual causes – mitochondrial disorders, CADASIL, migraine
InnovationsThe Comprehensive Stroke Center’s connection with Case Western Reserve University School of Medicine enables basic science research to be translated to findings that will improve future patient care. Recent major activities include:
• Joseph LaManna, PhD, Director of the BrainLab, has been involved in cerebral blood flow and metabolism research for over 30 years. Dr. LaManna is investigating energy demand, energy metabolism and blood flow in the brain, as well as the roles of mechanisms associated with tissue response to pathological insults such as stroke (cerebral edema), hypoxia and seizures.
• Sophia Sundararajan, MD, PhD, is leading an NIH-funded, K08-award investigating the role of PPAR agonists to limit inflammation and damage caused by a stroke.
• Janis J. Daly, PhD, MS, Director, Cognitive and Motor Learning Research Program, EUREKA study to treat the brain (where the stroke occurred), using electroencephalography (EEG) signals to direct brain retraining following stroke to measure the potential to more completely restore normal brain and motor function to a greater number of patients in shorter rehabilitation time.
COMPREHENSIVE STROKE CENTER
Current clinical trialsThe Comprehensive Stroke Center participates in groundbreaking clinical research trials to provide patients with access to therapies that are not otherwise available or reimbursed by their insurance.
• Surgical Rehearsal Platform (SRP). Surgical Rehearsal Platform is software that provides virtual imagery for high-risk, open/classic surgery; and cerebral aneurysm clipping. This technology enables the surgeon to gain currently unobtainable presurgery insights needed to refine the performance of time-critical tasks on a patient-specific basis. The main objective of this clinical study is to determine if the use of the SRP will lead to improved effort and time efficiency in cerebral aneurysm surgery. We will be looking at the number of clipping attempts and adjustments, time of temporary occlusion, number of clips wasted and other surgical data.
• CLEAR. The purpose of this Phase III randomized clinical trial (RCT) is to compare a policy of early extraventricular drain (EVD) use and recombinant tissue plasminogen activator (rt-PA, Cathflo® Activase® Genentech, Inc., San Francisco, CA) with EVD use and placebo (normal saline) the treatment of subjects with intracerebral hemorrhage (ICH) and intraventricular hemorrhage (IVH) with obstruction of the third or fourth ventricles by blood. We will evaluate a population of 500 ICH subjects with intraventricular hemorrhage, representative of current clinical practice and national demographics of ICH.
• Athersys. The primary objectives of this trial are the following:
- To determine the highest well-tolerated and safest single dose of MultiStem up to a maximum of 1200 million total cells in subjects with ischemic stroke and
- To determine the efficacy of MultiStem on functional outcome in subjects with ischemic stroke.
The secondary objectives of this trial are the following:
- To determine the safety of MultiStem in subjects with ischemic stroke and
- To determine changes in functional outcomes and disease severity outcomes of ischemic stroke in subjects treated with MultiStem.
The exploratory objectives of this trial are to evaluate changes in brain and spleen imaging metrics and blood biomarker outcomes as well as the incidence of infection (local and systemic) in ischemic stroke subjects treated with MultiStem.
• ATACH-II. To determine the therapeutic benefit of intensive SBP treatment (SBP<140 mmHg) compared with standard SBP treatment (SBP<180 mmHg) in reducing the proportion of patients with death and disability (mRS of 4-6) at Day 90 among subjects with ICH treated within 3.5 hours of symptom onset.
• StrokeNet. The StrokeNet grant is a new way of operating and conducting collaborative clinical NIH trials across the country. Cleveland has been chosen as a Regional Coordinating Center which is comprised of the four major health care institutions (CCF, Metro, UH, VA) along with its satellite hospital systems to conduct NIH stroke and neurology research. What makes this unique is that all four institutions and its corresponding satellite hospitals will operate and conduct clinical research trials under one financial budget and contract and utilize one central IRB. This will allow for us to maximize efficiencies in the development, promotion and conduct of multisite exploratory Phase I, II and confirmatory Phase III clinical trials in stroke prevention, treatment and recovery that are funded by NIH.
ProgramsDedicated Stroke Prevention Clinic:
• Initial evaluation, ongoing therapy with rehabilitation specialists who employ state-of-the-art techniques to speed recovery after stroke and management of co-morbid conditions.
• Neuroscience Intensive Care Unit staffed by neurointensivists and specialty-trained nurses providing round-the-clock care for critically ill patients.
Pediatric Neurosurgery:
Our expert neurosurgeons are skilled in the latest approaches and use the latest technologies to provide customized surgical solutions to pediatric patients with a wide variety of neurological conditions.
Special equipment:• Extensive array of diagnostic modalities including MR diffusion/
perfusion, MRA, MRV, CTA, CT perfusion, SPECT, PET, carotid duplex and Transcranial Doppler
To access the stroke team at UH Case Medical Center 24/7 for patient transfers or urgent advice, call the transfer line at 216-844-1111.
For patients or physicians requesting outpatient consults, second opinions or stroke prevention trials call 216-844-2724.
UH Case Medical Center was the first certified Comprehensive Stroke Center in Northeast Ohio.
This certification showcases our ability to treat the most complex cases and deliver the highest quality stroke care in the region.
COMPREHENSIVE STROKE CENTER
UHhospitals.org/Neuro • UH Neurological Institute | 2120 | University Hospitals • 216-844-2724
Sophia Sundararajan, MDOffice Phone: 216-844-8421Appointment Phone: 216-844-2724
Special Interests: Cerebrovascular Disorders, Acute Intervention, Stroke Recovery, Stroke, Acute Stroke Treatment, TIA
Sees Patients at: UH Case Medical Center,UH Mentor Health Center
Jeffrey L. Sunshine, MD, PhDOffice Phone: 216-844-3112Appointment Phone: 216-844-3112
Special Interests: Neuroradiology, Interventional Neuroradiology, Head and Neck Imaging, MRI, Acute Stroke Treatment, Brain Aneurysm, Carotid Stenosis, Brain and Spine AVM, Intracranial Stenosis, MR Imaging Head, Neck, Spine
Sees Patients at: UH Case Medical Center
Tanvir U. Syed, MDOffice Phone: 440-827-5061Appointment Phone: 216-844-2724
Special Interests: Intraoperative Monitoring, Epilepsy, Language Mapping, Higher Cortical Functions, Pseudoseizures, Outcomes Research, Biostatistics, Psychogenic Nonepileptic Seizures
Sees Patients at: UH Westlake Health Center, St. John Medical Center, UH Medina Health Center
Robert W. Tarr, MDOffice Phone: 216-844-5722
Special Interests: Neuroradiology, Interventional Neuroradiology
Sees Patients at: UH Case Medical Center
Colleen B. Tomcik, MDOffice Phone: 440-735-4723Appointment Phone: 216-844-2724
Special Interests: Higher Cortical Functions, Medical Education, Neurology, Headache
Sees Patients at: UH Case Medical Center, UH Bedford Medical Center, UH Twinsburg Health Center,UH University Suburban Health Center
Mark Walker, MDOffice Phone: 216-286-0315Appointment Phone: 216-286-0315
Special Interests: Vestibular Disorders, Vertigo, Eye Movement Disorders, Nystagmus, Cerebellar Ataxia
Sees Patients at: UH Case Medical Center
Norton A. Winer, MDOffice Phone: 216-383-7850Appointment Phone: 216-383-7850
Special Interests: Stroke, Sports Related Neurological Injuries, Cerebrovascular Disease, Carotid Ultrasonography, Pain Management
Sees Patients at: UH Euclid Health Center,UH Mentor Health Center
Wei Xiong, MDOffice Phone: 216-844-0474Appointment Phone: 216-844-2724
Special Interests: Stroke, Hypothermia, Neurocritical Care, Cardiac Arrest
Sees Patients at: UH Geauga Medical Center
COMPREHENSIVE STROKE CENTER
Cathy A. Sila, MDOffice Phone: 216-844-8934Appointment Phone: 216-844-2724
Special Interests: Stroke in the Young, Stroke, TIA, Intracranial Stenosis, PFO, Cerebral Vasculitis, Carotid Stenosis, Dissection, Stroke Prevention
Sees Patients at: UH Case Medical Center, UH Ahuja Medical Center
Nicholas C. Bambakidis, MDOffice Phone: 216-844-8758Appointment Phone: 216-844-2724
Special Interests: Spinal Cord Injuries, Traumatic Brain Injury, Skull Base Surgery, Cerebrovascular Surgery
Sees Patients at: UH Case Medical Center, UH Ahuja Medical Center
Marek A. Buczek, MD, PhDOffice Phone: 440-250-5303Appointment Phone: 216-250-5303
Special Interests: General Neurology, Electrophysiology, Headache, Chronic Pain Syndromes, EMG, Head Injury
Sees Patients at: UH Case Medical Center, UH Westlake Health Center, St. John Medical Center
Michael DeGeorgia, MDOffice Phone: 216-844-1552Appointment Phone: 216-844-2724
Special Interests: Critical Care Bioinformatics, Hemorrhagic Stroke, Hypothermia, ICU Monitoring, Ischemic Stroke, Neurocritical Care
Sees Patients at: UH Case Medical Center
Stefan Dupont, MD, PhDOffice Phone: 216-285-5041Appointment Phone: 216-844-2724
Special Interests: Neurology, Vascular Neurology
Sees Patients at: UH Ahuja Medical Center
Ciro Estabenez, MDOffice Phone: 216-844-3192
Appointment Phone: 216-844-2724
Special Interests: General Neurology, Neuromuscular
Disorders, Neurocritical Care, Stroke
Sees Patients at: UH Case Medical Center
Anthony J. Furlan, MDOffice Phone: 216-844-3193Appointment Phone: 216-844-2724
Special Interests: PFO, Thrombolysis, Heart Disease and Stroke, Acute Stroke Treatment, Stroke, Cerebrovascular Disorders, Stroke Systems and Outcomes
Sees Patients at: UH Case Medical Center, UH Ahuja Medical Center
Daniel W. Miller, MDOffice Phone: 216-844-7380Appointment Phone: 216-844-3192
Special Interests: General Neurology, Neuromuscular Disorders, Neurophysiology, EMG
Sees Patients at: UH Case Medical Center, UH University Suburban Health Center
Mark Rorick, MDOffice Phone: 440-285-2888Appointment Phone: 216-844-2724
Special Interest: General Neurology
Sees Patients at: UH Geauga Medical Center, UH Mentor Health Center
Warren R. Selman, MDOffice Phone: 216-844-5745Appointment Phone: 216-844-2724
Special Interests: Cerebrovascular Surgery, Aneurysms, Arteriovenous Malformations and Occlusive Disorders
Sees Patients at: UH Case Medical Center
COMPREHENSIVE STROKE CENTER
UHhospitals.org/Neuro • UH Neurological Institute | 2322 | University Hospitals • 216-844-2724
With level IV designations from the National Association of
Epilepsy Centers, the Epilepsy Center at UH Case Medical
Center and the Epilepsy Center at UH Rainbow Babies &
Children’s Hospital provide services to adult and pediatric
patients for consults or after previous treatments have failed.
Personalized treatment plans include clinical drug trials, novel
medications and advanced surgical therapies. Epileptologists
accurately classify, quantify and localize seizure-producing
areas of the patient’s brain by using the most advanced
diagnostic methods. The Epilepsy Center at UH Case Medical
Center and the Epilepsy Center at UH Rainbow Babies &
Children’s Hospital work together to deliver comprehensive
lifetime management of epilepsy and are national
destinations for both children and adults needing
surgery and complex treatment for epilepsy.
Surgical solutionsSeizures that do not respond to pharmaceutical management may be reduced or eliminated through epilepsy surgery. Advances in presurgical diagnostic techniques, including brain-mapping, expand therapeutic options to a larger percentage of epileptic patients.
• Temporal lobe resections
• Extratemporal lobe resections
• Lesionectomies
• Corpus callosum sections
• Selective amygdalo-hippocampectomies
• Multiple subpial transections
• Multiple hippocampal transections
• Hemispherectomies
• Vagal nerve stimulations
• Stereo-Electroencephalography (sEEG)
Minimally invasive and nonsurgical solutions:• Precise, noninvasive localization of epileptic foci by source-imaging
the electric or magnetic signal directly on the patient’s MRI
• Specialized MRI epilepsy-specific imaging protocols using 4 Tesla MRI, which can detect formerly hidden lesions
Conditions treatedThe epileptologists at UH specialize in all types of epilepsy, including:
• Adult epilepsy
• Developmentally delayed epilepsy
• Geriatric epilepsy
• Intractable epilepsy
• New onset epilepsy
• Pediatric epilepsy
• Women’s epilepsy
Innovations:• Cortical stimulation identifies brain areas involved with specific
cognitive functions like reading, writing and mathematical calculations, recognition of faces, etc.
• Cortico-cortical evoked potentials uncover brain to brain connections
• Advanced computer programs permit automatic recognition of the interictal and ictal epileptiform activity
• Multiple hippocampal transections reduce seizure activity while preserving memory functions
EPILEPSY CENTER
Current clinical trialsUH researchers are pioneering advances in the understanding of and causes of seizures through participation in various clinical and surgical studies including:
• The PRISM Project (1-P20-NS076965-01) is a National Institutes of Health (National Institute of Neurological Disorders and Stroke) funded multidisciplinary, multicenter collaboration between clinician researchers, basic scientists and expert engineers in bioinformatics and electrical engineering based at Case Western Reserve University. Its primary remit is to establish and facilitate research into Sudden Unexpected Death in Epilepsy (SUDEP), a significant, devastating public health problem that affects up to 5,000 individuals every year in the United States alone. In order to collect enough large-scale, multimodal physiological data for SUDEP patients, the project aims to establish a novel, online, web-based seizure data acquisition system capable of handling multimodal data, which will facilitate the bioinformatics core for sharing data with multiple epilepsy centers across the country.
• Targeted Self-Management for Epilepsy and Mental Illness: Epilepsy affects approximately 2 million Americans and is associated with substantial disability and a significantly increased risk of mortality and injury. Serious mental illnesses (SMI) such as psychotic conditions, bipolar disorder and chronic depression are common in people with epilepsy. This project targets the historically hard-to-reach group of individuals with epilepsy and with serious persistent mental illness (E-SMI), and will refine an intervention adapted for use in people with E-SMI, with the intent to improve both neurological and mental health outcomes.
• StrokeNet: The StrokeNet grant is a new way of operating and conducting collaborative clinical NIH trials across the country. Cleveland has been chosen as a Regional Coordinating Center which is comprised of the four major health care institutions (CCF, Metro, UH, VA) along with its satellite hospital systems to conduct NIH stroke and neurology research. What makes this unique is that all four institutions and its corresponding satellite hospitals will operate and conduct clinical research trials under one financial budget and contract and utilize one central IRB. This will allow for us to maximize efficiencies in the development, promotion and conduct of multisite exploratory Phase I, II and confirmatory Phase III clinical trials in stroke prevention, treatment and recovery that are funded by NIH.
Advances in presurgical diagnostic techniques, including brain-mapping, now offer surgical options to a significantly larger percentage of epileptic patients with medically intractable seizures.
Programs:• Epilepsy Monitoring Units (EMU): Provides separate units for
both adult and pediatric patients where anti-epileptic medications are reduced or removed and seizures are recorded with video/EEG to more precisely diagnose the type of epilepsy a patient has. Monitoring is also used to precisely localize the epileptogenic focus in patients who are candidates for epilepsy surgery.
• The UH Electroneurodiagnostics (END) Lab: Provides comprehensive testing of the electrical activity of the brain and nervous systems. The lab is equipped with electroencephalogram (EEG), continuous video EEG monitoring and evoked potentials. We also offer technology used for monitoring EEG or evoked potentials during surgery for brain or spinal cord tumor, trauma, aneurysm, vascular malformations or blockage, congenital abnormalities, spinal cord malformations, epilepsy surgery and movement disorders.
• Epilepsy Transition Clinic: In collaboration with the Epilepsy Center at UH Rainbow Babies & Children’s Hospital, the Epilepsy Transition Clinic provides continuity of care as adolescent epilepsy patients transition to adult care. The clinic is comprised of both adult and pediatric epileptologists and is designed to create a seamless transition of care to patients entering adulthood who have continuing medical issues. The primary objectives of this teenager clinic are to address the unique needs and concerns of this age group and, importantly, to facilitate a smooth handover of specialist epilepsy care from pediatric to adult services.
• Intra-operative monitoring (IOM): Provides comprehensive monitoring of evoked potentials and other neurophysiologic parameters during surgery to immediately identify changes in brain, spinal cord and peripheral nerve function prior to irreversible damage. IOM also is effective in localizing anatomical structures, including peripheral nerves and sensorimotor cortex, which helps guide the surgeon during dissection.
Specialized equipment:• 4 Tesla MRI
• Functional MRI
• Intracarotid amobarbital testing
• Ictal SPECT scans
• Mapping of seizure onset zones
• PET scans
• Specialized MRI epilepsy-specific imaging protocols
EPILEPSY CENTER
UHhospitals.org/Neuro • UH Neurological Institute | 2524 | University Hospitals • 216-844-2724
EPILEPSY CENTER
Samden Lhatoo, MDOffice Phone: 216-844-5855Appointment Phone: 216-844-2724
Special Interests: Epilepsy, Neurophysiology
Sees Patients at: UH Case Medical Center, UH Ahuja Medical Center
Hans O. Lüders, MDOffice Phone: 216-844-3650Appointment Phone: 216-844-2724
Special Interests: Clinical Neurophysiology, Higher Cortical Functions, EEG – Electroencephalography, Epilepsy, Language Mapping
Sees Patients at: UH Case Medical Center
Shahram Amina, MDOffice Phone: 216-844-3675Appointment Phone: 216-844-2724
Special Interest: Epilepsy
Sees Patients at: UH Ahuja Medical Center, UH University Suburban Health Center
Fareeha Ashraf, MDOffice Phone: 216-844-3192Appointment Phone: 216-844-2724
Special Interests: Epilepsy, Sleep Medicine, Hypersomnia, Sleep Apnea, Sleep Related Movement Disorder, Sleep Breathing Disorders
Sees Patients at: UH Case Medical Center, UH Ahuja Medical Center
Michael W. Devereaux, MDOffice Phone: 216-844-3591Appointment Phone: 216-844-2724
Special Interests: Multiple Sclerosis, Epilepsy, General Neurology, Neuro-ophthalmology
Sees Patients at: UH Case Medical Center, UH Ahuja Medical Center, UH Richmond Medical Center, UH University Suburban Health Center, UH Geneva Medical Center, UH Medina Health Center
Matthew Eccher, MD, MSPHOffice Phone: 216-844-1764Appointment Phone: 216-844-2724
Special Interests: Epilepsy, Disorders of Consciousness, Clinical Neurophysiology
Sees Patients at: UH Case Medical Center, UH Ahuja Medical Center, UH University Suburban Health Center
Pamela Lang, CNSOffice Phone: 216-844-5383Appointment Phone: 216-844-2724
Special Interest: Epilepsy
Sees Patients at: UH Case Medical Center, UH University Suburban Health Center
Joseph A. Locala, MDOffice Phone: 216-844-2400Appointment Phone: 216-844-2400
Special Interests: Adult Psychiatry, Psychosomatic Psychiatry, Psychiatric Care of Medically Ill Patients, Transplant Psychiatry, Mood Disorders in the Medically Ill, Anxiety Disorders in the Medically Ill
Sees Patients at: UH Case Medical Center, UH Seidman Cancer Center, W.O. Walker Center
Jonathan Miller, MDOffice Phone: 216-844-3470Appointment Phone: 216-844-2724
Special Interest: Epilepsy Surgery
Sees Patients at: UH Case Medical Center
Jennifer Sweet, MDOffice Phone: 216-983-3334Appointment Phone: 216-844-2724
Special Interest: Epilepsy Surgery
Sees Patients at: UH Case Medical Center
Tanvir U. Syed, MDOffice Phone: 440-827-5061Appointment Phone: 216-844-2724
Special Interests: Intraoperative Monitoring, Epilepsy, Language Mapping, Higher Cortical Functions, Pseudoseizures, Outcomes Research, Biostatistics, Psychogenic Nonepileptic Seizures
Sees Patients at: UH Westlake Health Center, St. John Medical Center, UH Medina Health Center
Epilepsy Center at UH Rainbow Babies & Children’s Hospital University Hospitals Rainbow Babies & Children’s Hospital is
a national leader in pediatric epilepsy diagnosis, treatment
and management. With a focus on helping patients enjoy
a healthy and seizure-free life, our pediatric epilepsy team
delivers comprehensive, family-centered care to infants,
children and teens.
Accurate diagnosisComprehensive assessments and state-of-the-art tests, including an inpatient pediatric video EEG monitoring unit and high-resolution MRI, PET and SPECT imaging technologies, accurately diagnose new onset seizures, spells that mimic seizures and epileptic disorders due to many different causes.
Best practices in pediatric epilepsy managementIndividualized approach to patient care incorporates specialized programs, newer medications, advanced surgery and other innovative therapies – all closely monitored by pediatric epileptologists, neurosurgeons and epilepsy nurses.
Surgical therapyPediatric epileptologists perform an extensive presurgical evaluation with modern invasive electrode technology and work with experienced pediatric neurosurgeons, radiologists, neuropsychologists and psychiatrists to treat seizures with specialized and individually tailored brain surgery.
Level IV Pediatric Epilepsy CenterRecognized with the highest level designation by the National Association of Epilepsy Centers.
Convenient accessOutpatient services provided at community locations across the region and an expert call center that guides medication adjustments to reduce side effects and improve outcomes.
New Onset Seizure ClinicThe new onset seizure clinic provides expert diagnostic services, referrals, treatment and follow-up care for children who experience a first seizure. The outpatient program offers rapid access to care, and was developed as part of the hospital’s increased focus on pediatric neurology and epilepsy. The key to effectively treating children with seizures starts with an accurate diagnosis. This includes imaging the brain and performing EEG testing to record brain activity. This helps to confirm the diagnosis, identify the cause of seizures and initiate appropriate treatment with medications. We counsel patients on safety issues and behaviors that may reduce the risk for further seizures. Neuropsychologic screening is available to screen for possible academic and behavior problems. We offer and develop individualized care plans for children who have experienced new onset seizures.
Jonathan Miller, MDOffice Phone: 216-844-3470Appointment Phone: 216-844-2724
Special Interests: Pain Neurosurgery, Movement Disorders Surgery, Cancer Pain, Facial Pain, Peripheral Nerve Surgery, Stereotatic & Functional Neurosurgery, Epilepsy Surgery, Gamma Knife® Stereotactic Radiosurgery, Neuro-oncology
Sees Patients at: UH Case Medical Center
Asim Shahid, MDOffice Phone: 216-286-3691Appointment Phone: 1-866-UH4-PEDS
Special Interests: Electroencephalography, Pediatric Epilepsy, Pediatric Neurology
Sees Patients at: UH Rainbow Babies & Children’s Hospital, UH Landerbrook Health Center, UH Westlake Health Center
Jun Park, MDOffice Phone: 216-286-6644Appointment Phone: 1-866-UH4-CARE
Special Interests: Intractable Epilepsy, Cortical Dysplasia, Tuberous Sclerosis, Neonatal Stroke, Infantile Spasms, Seizures in Infancy, Post-traumatic Epilepsy, Vagal Nerve Stimulation
Sees Patients at: UH Rainbow Babies & Children’s Hospital
Rachel B. Tangen, PhDOffice Phone: 216-844-3230Appointment Phone: 1-866-UH4-CARE
Special Interests: Neuropsychology, Pediatric Brain Disease, Brain Injury, Neuropsychological/ Learning Evaluations, Seizure Disorders, Cochlear Implantation
Sees Patients at: W.O. Walker Center
EPILEPSY CENTER
UHhospitals.org/Neuro • UH Neurological Institute | 2726 | University Hospitals • 216-844-2724
UH Neurological Institute’s Functional & Restorative
Neurosurgery Center is dedicated to the restoration
of function affected by neurological disease and the
development of new technologies to improve brain health.
The center is focused on the electrical or pharmacologic modification of neurological activity through neuromodulation therapies, including alterations of nerve function through electrical stimulation or ablation and direct delivery of medication to the nervous system. These advanced procedures provide options for patients with conditions and symptoms that aren’t responding optimally to standard medical management.
The primary surgical treatment for restoring neurological function is deep brain stimulation (DBS). However, our nationally recognized neurosurgeons also perform a wide variety of restorative procedures including vagal nerve stimulation and targeted cranial surgical resections for the treatment of refractory epilepsy, spinal cord and peripheral nerve stimulation, surgical treatment of facial pain, stereotactic radiosurgery and intrathecal drug delivery.
Conditions treated:• Chronic neuropathic pain
Trigeminal neuralgiaFailed back surgery syndrome (postlaminectomy)Chronic regional pain syndrome/reflex sympathetic dystrophyOccipital neuralgiaAnesthesia dolorosaDeafferentation pain (brachial plexus avulsion, cancer pain)
• EpilepsyMedically refractory epilepsy (adult and pediatric)Neuromodulation for epilepsy
• Movement disordersEssential tremorParkinson’s diseaseCervical dystoniaGeneralized dystonia
• Peripheral nerve disordersEntrapment neuropathy (carpal tunnel, ulnar neuropathy, peroneal neuropathy)Post-herniorraphy ilioinguinal neuralgiaPeripheral nerve tumorsPeripheral nerve trauma (brachial plexus, nerve injuries)
• PsychosurgeryObsessive-compulsive disease
• SpasticityCerebral palsyMultiple sclerosisSpastic hemiplegia/paraplegia/tetraplegia due to stroke or trauma
Innovations:• First in North America to perform DBS of the thalamus to treat
symptoms of Tourette syndrome successfully.
• The first group worldwide to complete a prospective randomized double blinded trial of thalamic DBS for Tourette syndrome in a pilot clinical trial of five patients.
Programs:• Deep Brain Stimulation: Manages tremors, movement and walking
problems via surgical implantation of electrodes in the brain and pulse generators in the upper chest just beneath the collarbones.
• Spinal Cord Stimulation: Uses spinal cord neurostimulators that deliver targeted chronic pain management. The neurostimulator is inserted under the skin through a small incision in the upper buttock, while the long-term lead is implanted in the epidural space of the spinal cord.
• Intrathecal Drug Delivery: Also known as the “pain pump” or “baclofen pump,” this simple procedure uses a small pump to deliver medication directly to your spinal cord. The pump is surgically placed under the abdominal skin and delivers medication through a catheter to the area around your spinal cord. Effective in treating chronic pain and spasticity.
• Surgical Treatment of Epilepsy: Seizures that do not respond to pharmaceutical management may be reduced or eliminated through epilepsy surgery. Advances in presurgical diagnostic techniques, including brainmapping, expand therapeutic options to a larger percentage of epileptic patients.
• Surgical Treatment of Facial Pain: Accurately identifies source of pain before devising customized surgical treatments. Surgical solutions are available to relieve pain associated with trigeminal neuralgia, multiple sclerosis, tumors and a variety of other neuropathies.
• Pediatric Neurosurgery: Our expert neurosurgeons are skilled in the latest approaches and use the latest technologies to provide customized surgical solutions to pediatric patients with a wide variety of neurological conditions.
Current clinical trials:• BrainGate2. Feasibility Study of an Intracortical Neural Interface
System for Persons with Tetraplegia. Obtain preliminary device safety information and demonstrate proof of principle (feasibility of efficacy) of the ability of people with tetraplegia to control a computer cursor and other assistive devices with their thoughts. Prospective, open-label, feasibility study. Primary Endpoint: Safety: Sensor successfully implanted, not explanted for safety reasons during the one-year post-implant evaluation, and there are no device-related Serious Adverse Events which result in death or permanently increased disability during the one-year post-implant evaluation period.
FUNCTIONAL & RESTORATIVE NEUROSURGERY CENTER
Jonathan Miller, MDOffice Phone: 216-844-3470Appointment Phone: 216-844-2724
Special Interests: Pain Neurosurgery, Movement Disorders Surgery, Facial Pain, Peripheral Nerve Surgery, Stereotatic & Functional Neurosurgery, Epilepsy Surgery, Gamma Knife® Stereotactic Radiosurgery
Sees Patients at: UH Case Medical Center
Mirza Baig, MDOffice Phone: 216-286-6486Appointment Phone: 1-866-UH4-CARE
Special Interests: Physical Medicine, Rehabilitation
Sees Patients at: UH Case Medical Center, UH Rehabilitation Hospital
Bashar Katirji, MDOffice Phone: 216-844-4854Appointment Phone: 216-844-2724
Special Interests: Peripheral Nerve Disorders, Neuromuscular Disorders, Amyotrophic Lateral Sclerosis, Myasthenia Gravis, Entrapment Neuropathies, Electrodiagnosis, EMG
Sees Patients at: UH Case Medical Center, UH AhujaMedical Center, UH University Suburban Health Center
Samden Lhatoo, MDOffice Phone: 216-844-5855Appointment Phone: 216-844-2724
Special Interests: Epilepsy, Neurophysiology
Sees Patients at: UH Case Medical Center,UH Ahuja Medical Center
David Ryan, MDOffice Phone: 440-816-2850Appointment Phone: 440-816-2850
Special Interests: Anesthesiology, Pain Management, Interventional Treatments Including Radio Frequency and Ablation, Neuromodulation for Cervicogenic and Migraine Headache, Infusion Therapies, Sympathetic Mediated Pain
Sees Patients at: Southwest General Health Center
Asim Shahid, MDOffice Phone: 216-286-3691Appointment Phone: 1-866-UH4-PEDS
Special Interests: Electroencephalography, Pediatric Epilepsy, Pediatric Neurology
Sees Patients at: UH Rainbow Babies & Children’s Hospital, UH Landerbrook Health Center, UH Westlake Health Center
Barbara E. Shapiro, MD, PhDOffice Phone: 216-844-7768Appointment Phone: 216-844-2724
Special Interests: Lysosomal Disorders, EMG, Tay-Sachs Disease, Peripheral Neuropathy, Metabolic & Muscular Dystrophy, Neuromuscular Disorders
Sees Patients at: UH Case Medical Center,UH Ahuja Medical Center
Jennifer Sweet, MDOffice Phone: 216-983-3334Appointment Phone: 216-844-2724
Special Interests: Pain Neurosurgery, Movement Disorders Surgery, Cancer Pain, Facial Pain, Peripheral Nerve Surgery, Stereotatic & Functional Neurosurgery, Epilepsy Surgery, Gamma Knife®, Stereotactic Radiosurgery, Neuro-oncology
Sees Patients at: UH Case Medical Center
Benjamin L. Walter, MDOffice Phone: 216-844-8285Appointment Phone: 216-844-2724
Special Interests: Dystonia, Tremors, Movement Disorders, Functional Magnetic Resonance Imaging (MRI), Mechanisms of Effect of DBS, Deep Brain Stimulation, Parkinson’s Disease
Sees Patients at: UH Case Medical Center,UH University Suburban Health Center,UH Medina Health Center, UH Westlake Health Center
FUNCTIONAL & RESTORATIVE NEUROSURGERY CENTER
UHhospitals.org/Neuro • UH Neurological Institute | 2928 | University Hospitals • 216-844-2724
MUSIC & MEDICINE CENTER
Recognizing that musicians often develop unique medical
problems that can be devastating to their musical abilities and
careers, the UH Neurological Institute established the Music
& Medicine Center. Clinical trials, specialized equipment,
and innovative treatment options make UH Case Medical
Center uniquely qualified to correctly diagnose and manage
music-related injuries. A full range of patient services relevant
to music-related medical problems is available through the
Music & Medicine Wellness Program.
UH Case Medical Center and Case Western Reserve University School of Medicine collectively have physician-scientists covering the entire spectrum of care, from perception of music, speech and voice, to memory and motor performance.
Musician wellness program and treatment of music-related injuries:• Tinnitus
• Musculoskeletal disorders
• Dizziness
• Voice and throat disorders
• Hearing loss
• Pulmonary disorders
• Depression
• Memory loss
• Visual loss
Neuromuscular disorders:• Overuse Syndrome
• Neural Impingement
• Focal Dystonia
Psychiatric disorders:• Anxiety
• Bipolar Disorder
• Depression & Substance Use
Otological disorders:• Hearing Loss
• Tinnitus & Vertigo
Laryngological disorders:• Laryngitis
• Voice Disturbance
• Aphonia
Michael DeGeorgia, MDOffice Phone: 216-844-1552Appointment Phone: 216-844-2724
Special Interests: Critical Care Bioinformatics, Hemorrhagic Stroke, Hypothermia, ICU Monitoring, Ischemic Stroke, Neurocritical Care
Sees Patients at: UH Case Medical Center
Jonathan Lass, MDOffice Phone: 216-844-8590Appointment Phone: 216-844-3601
Special Interests: Cataract and Lens Implant Surgery, Corneal and External Diseases, Corneal Transplantation, Eye Exams, Eye Injury, Eye Trauma, Intra-ocular Lenses, IOL, Ophthalmology, Vision Exams
Sees Patients at: UH Case Medical Center, UH Landerbrook Health Center, UH Lyndhurst Surgery Center
Alan J. Lerner, MDOffice Phone: 216-464-6412Appointment Phone: 216-464-6445
Special Interests: Alzheimer’s Disease, Dementia, Behavioral Neurology, General Neurology, Higher Cortical Functions, Adult Attention Deficit Disorder (adult ADD/ADHD)
Sees Patients at: UH Ahuja Medical Center, UH Foley ElderHealth Center
Hans O. Lüders, MDOffice Phone: 216-844-3650Appointment Phone: 216-844-2724
Special Interests: Clinical Neurophysiology, EEG – Electroencephalography, Epilepsy, Higher Cortical Functions, Language Mapping
Sees Patients at: UH Case Medical Center
Nicole Maronian, MDOffice Phone: 216-983-3455 Appointment Phone: 216-844-2724
Special Interests: Ear, Nose & Throat, Head and Neck Cancer, Otolaryngology, Voice and Swallowing Disorders
Sees Patients at: UH Case Medical Center
Cliff A. Megerian, MDOffice Phone: 216-844-5500Appointment Phone: 216-844-6000
Special Interests: Hearing Loss, Otitis, Chronic Ear Disease, Surgery for Hearing Loss and Tumor, Vertigo, Meniere’s Disease, Dizziness, Neurotology, Skull Based Surgery, Acoustic Neuromas
Sees Patients at: UH Case Medical Center, UH Chagrin Highlands Health Center, UH Westlake Health Center
Jonathan Miller, MDOffice Phone: 216-844-3470Appointment Phone: 216-844-2724
Special Interests: Pain Neurosurgery, Movement Disorders Surgery, Cancer Pain, Facial Pain, Peripheral Nerve Surgery, Stereotatic & Functional Neurosurgery, Epilepsy Surgery, Gamma Knife® Stereotactic Radiosurgery, Neuro-oncology
Sees Patients at: UH Case Medical Center
Gail Murray, PhD, MEdOffice Phone: 216-844-8168Appointment Phone: 216-844-7191
Special Interests: Pediatric Audiology, Central Audiotory Processing, Cochlear Implantation
Sees Patients at: UH Rainbow Babies & Children’s Hospital, UH Chagrin Highlands Health Center
David C. Preston, MDOffice Phone: 216-844-7776Appointment Phone: 216-844-2724
Special Interests: Neuromuscular Disorders, Electrophysiology, Myasthenia Gravis, Entrapment Neuropathies, Peripheral Neuropathies, Peripheral Nerve Disorders
Sees Patients at: UH Case Medical Center, UH University Suburban Health Center, UH Richmond Medical Center
Robert J. Ronis, MD, MPHOffice Phone: 216-844-3883Appointment Phone: 216-844-3883
Special Interests: Community Psychiatry, Adult Ambulatory, Psychopharmacology, Chemical Dependency, Psychotherapy, Addiction Psychiatry, Community Mental Health
Sees Patients at: W.O. Walker Center
Robert Schilz, DO, PhDOffice Phone: 216-844-3201Appointment Phone: 216-844-7200
Special Interests: Bronchoscopy, Critical Care, Lung Transplantation, Pulmonary Vascular Disease
Sees Patients at: UH Case Medical Center
Maroun Semaan, MDOffice Phone: 216-844-8013Appointment Phone: 216-844-6000
Special Interests: Cochlear & Brainstem Implants, Facial Nerve & Balance Disorders, Hearing, Neuro Fibromatosis Type II, Skull Base Surgery
Sees Patients at: UH Case Medical Center, UH Chagrin Highlands Health Center, UH Twinsburg Health Center, UH Seidman Cancer Center – Westlake
Barbara E. Shapiro, MD, PhDOffice Phone: 216-844-7768Appointment Phone: 216-844-2724
Special Interests: Lysosomal Disorders, Tay-Sachs Disease, Peripheral Neuropathy, Metabolic & Muscular Dystrophy, Neuromuscular Disorders
Sees Patients at: UH Case Medical Center, UH Ahuja Medical Center
Benjamin L. Walter, MDOffice Phone: 216-844-8285Appointment Phone: 216-844-2724
Special Interests: Dystonia, Tremors, Movement Disorders, Functional Magnetic Resonance Imaging (MRI), Mechanisms of Effect of DBS, Deep Brain Stimulation, Parkinson’s Disease
Sees Patients at: UH Case Medical Center, UH University Suburban Health Center, UH Medina Health Center, UH Westlake Health Center
MUSIC & MEDICINE CENTER
UHhospitals.org/Neuro • UH Neurological Institute | 3130 | University Hospitals • 216-844-2724
NEUROCRITICAL CARE CENTER
UH Neurological Institute’s world-renowned Neurocritical
Care Center is one of only a few available in Ohio
and provides continuous state-of-the-art monitoring
and treatment for patients who are critically ill, need
postoperative care or require intensive neurological
monitoring. The Neurocritical Care Center is a dedicated,
multidisciplinary center structured to provide the best
patient care and improve communication and coordination
of research, while promoting education and advanced
administrative efficiency. It is the only such center for
neurocritical care in the Midwest.
Hospital staff at UH Case Medical Center as well as our community hospitals receive continuous training in the latest, most effective techniques and technology to benefit patient treatment. Studies show that involvement of a dedicated neurological intensive care team correlates to a significant reduction in length-of-stay and controlled cost and, most importantly, a reduction of in-hospital mortality and better patient outcomes.
Conditions treatedNeurocritical care is comprehensive multisystem care of the critically ill neurological patient. In the NSU, we care for a broad spectrum of patients including postoperative neurosurgical patients and patients with massive ischemic stroke, status epilepticus, encephalitis and neuromuscular respiratory failure, as well as trauma, intracerebral hemorrhage and subarachnoid hemorrhage.
ProgramsPediatric Neurosurgery: Our expert neurosurgeons are skilled in the latest approaches and use the latest technologies to provide customized surgical solutions to pediatric patients with a wide variety of trauma-related conditions.
InnovationsUniversity Hospitals created the world’s first neurological intensive care medicine practice nearly three decades ago. We literally “wrote the book” on neurocritical care (our textbook, Critical Care Neurology and Neurosurgery, is the standard textbook of the field). UH is one of 25 institutions in the United States that offers a fellowship in Neurocritical Care and our annual international CME conference is the benchmark meeting for the field.
University Hospitals is a world leader when it comes to heart and brain resuscitation after cardiac arrest. In fact, George Crile, MD, former Professor and Chief of Surgery at University Hospitals, was the first to successfully use external chest compression in 1903 and the first to use adrenaline (epinephrine) in resuscitation in 1909. Claude Beck, MD, Professor of Cardiothoracic Surgery, is credited with performing the first successful cardiac defibrillation in humans in 1947 and introduced the first CPR course for the lay public in 1958.
Continuing with this strong tradition, University Hospitals was one of the first institutions to adopt hypothermia after cardiac arrest to protect the brain from damage. We have been working closely with Cleveland EMS to cool patients as early as possible to achieve the best possible outcome. Michael DeGeorgia, MD, Director of the Neurocritical Care Center, is one of the world’s leading authorities in hypothermia.
Case Critical Care Bioinformatics Consortium: We believe the future of intensive care monitoring lies in:
(1) Integration and time-synchronization of multiple channels of physiological data continuously and simultaneously
(2) Processing of this data in real-time, using new tools such as multivariate analysis and nonlinear time series analysis
(3) Presenting this data to the clinician using innovative and intuitive clinician-centric visual displays
Special equipmentWe review minute-to-minute progress with the most advanced monitoring equipment in the world, including:
• Brain tissue oxygenation monitoring
• Cerebral blood flow monitoring
• Continuous video EEG monitoring
• CT angiography and CT perfusion studies
• Intracranial pressure monitoring
• MRI perfusion – diffusion imaging
• Positron Emission Tomography (PET)
• Transcranial Doppler (TCD) ultrasonography
These monitoring capabilities are combined with the latest interventions to save brain function, including:
• Burst suppression
• Cerebral angiography and intervention (angioplasty, stenting)
• Endovascular coiling
• Induced hypertension (Hypertensive hypervolemic hemodilution)
• Induced hypothermia
• Intravenous and intra-arterial thrombolysis
• Plasmapheresis
• Ventricular drainage
Mission of the center: • To improve patient care by implementing best medical
practices for acute neurological disorders. To foster clinical, experimental, and outcomes research focused on developing innovative interventions. To improve education of residents and fellows by developing standards for training in neurocritical care. To advance administrative efficiency and quality improvement. To deliver nursing care in a manner that promotes interdisciplinary collaboration, caring and compassion.
• To strive to be the world leader in neurocritical care.
Michael DeGeorgia, MDOffice Phone: 216-844-1552Appointment Phone: 216-844-2724
Special Interests: Critical Care Bioinformatics, Hemorrhagic Stroke, Hypothermia, ICU Monitoring, Ischemic Stroke, Neurocritical Care
Sees Patients at: UH Case Medical Center
Ciro Estabenez, MDOffice Phone: 216-844-3192
Appointment Phone: 216-844-2724
Special Interests: General Neurology, Neuromuscular
Disorders, Neurocritical Care, Stroke
Sees Patients at: UH Case Medical Center
Seth Alan Hoffer, MDOffice Phone: 216-844-5744Appointment Phone: 216-844-2724
Special Interests: Neurocritical Care, Spine Surgery
Sees Patients at: UH Case Medical Center, UH Richmond Medical Center, UH Bedford Medical Center
Wei Xiong, MDOffice Phone: 216-844-0474Appointment Phone: 216-844-2724
Special Interests: Stroke, Hypothermia, Neurocritical Care, Cardiac Arrest
Sees Patients at: UH Geauga Medical Center
NEUROCRITICAL CARE CENTER
UHhospitals.org/Neuro • UH Neurological Institute | 3332 | University Hospitals • 216-844-2724
UH Neurological Institute’s Neurological & Behavioral
Outcomes Center is one of the first centers of its kind
in the United States devoted exclusively to studying
outcomes and quality improvements in patients with
neurological conditions.
By establishing the center, the UH Neurological Institute is creating an infrastructure to accurately evaluate patient outcomes, refine performance improvement processes and increase health care value.
Contributions to neuroscienceThe Neurological & Behavioral Outcomes Center identifies, develops and assists with implementing methods and approaches that incorporate the latest education and research to deliver the highest value health care to patients with neurological disorders.
The center is committed to health promotion approaches that have the potential to advance health outcomes for patients with neurological and neuropsychiatric conditions. The Neurological & Behavioral Outcomes Center infrastructure is designed to generate new research and to help investigators shape their ideas into proposals and grant applications. Working with investigators from a variety of other local, regional, national and international research groups, center researchers have led and/or collaborated on projects covering a broad range of neuroscience topics. Collaborators include faculty at the Case Western Reserve University School of Medicine and School of Arts and Sciences, the Francis Payne Bolton School of Nursing, the Veterans Health Administration, MetroHealth Medical Center, the Case Western Reserve University Prevention Research Center, the Cleveland Clinic, University of Pennsylvania, University of Toronto, the Parkinson’s Research Institute in Milwaukee, Wis., The Ohio State University and Kent State
University. Recognizing the critical importance of preliminary data to continue a robust research trajectory, the Neurological & Behavioral Outcomes Center is also involved in pilot projects intended to support the submission of future grant applications, and to inform improvements in UH Neurological Institute clinical programming. Center researchers through Case Western Reserve University School of Medicine receive research funding from the National Institutes of Health (NIH), the Centers for Disease Control (CDC), National Science Foundation (NSF), national and regional foundations as well as industry and patient/consumer advocacy associations.
Focused on education, center faculty are engaged in mentoring junior UH Neurological Institute investigators and students in various stages of their research careers. Recently, the Neurological & Behavioral Outcomes Center faculty began leading the U.S.-based component of an NIH Medical Education Partnership Initiative to develop clinical and research training in neurological disorders in Uganda, Africa. Faculty are also active in teaching colleagues by speaking locally and internationally.
The center is also supported by an NIH Clinical and Translational Science Award (CTSA) to Case Western Reserve University School of Medicine. The university is one of 38 medical research institutions working together as a national consortium to improve the way biomedical research is conducted across the country. The consortium shares a common vision of reducing the time it takes for laboratory discoveries to become treatments for patients and to engage communities in clinical research efforts.
Martha Sajatovic, MDOffice Phone: 216-844-2808, 216-368-7572Appointment Phone: 216-844-2400
Special Interests: Adult Psychiatry, Geropsychiatry, Geriatric Psychiatry, Health Services, Bipolar Disorder, Treatment Adherence
Sees Patients at: W.O. Walker Center
NEUROLOGICAL & BEHAVIORAL OUTCOMES CENTER
UH Neurological Institute’s Neuromuscular Center has
established itself as one of America’s foremost institutions
for the treatment of complex neuromuscular disorders
by combining extensive clinical experience for a wide
variety of specialties.
UH provides diverse testing, diagnosis and treatment labs to address the full range of neuromuscular conditions. Labs are available at many community facilities and offer:
• Autonomic Laboratory: As one of only 12 such labs in the country, we test all aspects of autonomic function including cardiac, vasomotor and sudomotor (sweat) functions; and to diagnose chronic regional pain syndrome, peripheral neuropathies, Postural Orthostatic Tachycardia Syndrome (POTS) and syncope of unknown etiology. It provides full support in the assessment of patients seen in the interdisciplinary program clinics.
• Electromyography (EMG) Lab: The EMG Lab provides high-quality, state-of-the-art electrodiagnostic testing of neuromuscular disorders. The EMG test includes nerve conduction studies performed by the EMG technologists under physician supervision and the muscle needle examination performed by the EMG physician. Computerized EMG machines are available at all six EMG lab locations within the UH system. These machines enable lab personnel to perform detailed electrodiagnostic testing on every patient with instant report generation. Highly specialized testing such as single fiber EMG and quantitative testing are also offered.
Surgical solutions:• Diaphragmatic pacing for high cervical spinal cord injury and
patients with amyotrophic lateral sclerosis
Conditions treatedNeuromuscular conditions treated include:
• Amyotrophic lateral sclerosis (ALS)
• Cervical and lumbar radiculopathy
• Chronic inflammatory demyelinating polyneuropathy (CIDP)
• Entrapment neuropathies
• Guillain-Barre syndrome
• Muscular dystrophies
• Myasthenia gravis
• Peripheral neuropathy
• Polymyositis/Dermatomyositis
Autonomic conditions treated include:
• Orthostatic hypotension
• Syncope
• Small fiber neuropathies
• Postural tachycardia syndrome (POTS)
• Multiple system atrophy
• Hyperhidrosis
Current clinical trialsClinical research is a cornerstone in the treatment options Neuromuscular Center physicians offer to patients. Our physicians and scientists contribute to:
• ICEPAC NIH Grant: (Interstitial Cystitis Evaluation of Psychophysiologic and Autonomic Characteristics) – to understand the role of the nervous system in this debilitating chronic pain disorder, as well as in another pelvic pain disorder called myofascial pelvic pain syndrome.
The Neuromuscular Center is one of only a few nationwide participating in an NIH-Funded Trial testing the efficacy of thymectomy in the treatment of myasthenia gravis.
ProgramsFor the proper development of personalized patient treatment plans, the Neuromuscular Center has designated leading-edge diagnostic and treatment programs:
• Autonomic Disorders Interdisciplinary Program: This program provides interdisciplinary clinics for diagnosis and treatment for adults and children with mysterious episodes of dizziness, fainting, vomiting or unexplained stomach pain. Physicians also address complex regional pain syndrome, unexplained or unmanaged pain in the pelvic region and issues of excessive sweating or other sweat or flushing related issues.
• Amyotrophic Lateral Sclerosis (ALS) Program: This nationally renowned program takes an interdisciplinary approach by combining strengths of specialists from the Neuromuscular Center, pulmonary medicine, speech pathology and nutrition to manage the symptoms and treatment for each patient. UH uses diaphragmatic stimulation and pacing to help patients breathe and speak more normally, and it helps stave off respiratory complications during the progression of ALS.
NEUROMUSCULAR CENTER
UHhospitals.org/Neuro • UH Neurological Institute | 3534 | University Hospitals • 216-844-2724
NEUROMUSCULAR CENTER
Autonomic Lab ProgramThe Neuromuscular Center’s Autonomic Lab Program performs four different types of tests depending on the diagnosis of the referring physician:
• Autonomic Screen
• Reflex Sympathetic Dystrophy/Chronic Regional Pain Syndrome Screen
• Quantitative Sensory Test
• Thermoregulatory Sweat Test
• Myasthenia Gravis Program: For over a decade, patients have been treated with immunosuppressive drugs as well as plasma exchange and intravenous immunoglobulin.
• Muscular Disease Program: This program brings a multidisciplinary approach to the diagnosis and management of patients with inherited neuromuscular disorders, including muscular dystrophies and peripheral neuropathies, as well as acquired conditions such as postpolio-myelitis syndrome and inclusion body myositis.
Patient conveniencePerhaps the most significant benefit to patients is that they have access to expert consultation and advanced diagnostics close to home in our community facilities. In addition to the main UH Case Medical Center campus, our renowned specialists see patients at UH Bedford Medical Center, UH Richmond Medical Center, UH University Suburban Health Center and UH Westlake Health Center.
Same-Day EMG Services AvailableThe UH Neurological Institute announces the availability of same-day service for Nerve Conduction Studies and Electromyography (EMG) for your patients with suspected entrapment neuropathies, radiculopathies, peripheral neuropathies, and other complex nerve, muscle, anterior horn cell and NMJ disorders. To schedule a same-day EMG, call 216-844-1923.
Advanced diagnostic screening is available at:EMG Lab
UH Case Medical Center
UH Ahuja Medical Center
UH University Suburban Health Center
UH Westlake Health Center
Autonomic Lab
UH Case Medical Center
UH Ahuja Medical Center
UH Westlake Health Center
The Neuromuscular Center operates the first Diaphragmatic Pacing Center in the world. This center evaluates patients with spinal cord injury, ALS and other neurological disorders with early respiratory failure who may be candidates for diaphragm pacing systems..
Bashar Katirji, MDOffice Phone: 216-844-4854Appointment Phone: 216-844-2724
Special Interests: Peripheral Nerve Disorders, Neuromuscular Disorders, Amyotrophic Lateral Sclerosis, Myasthenia Gravis, Entrapment Neuropathies, Electrodiagnosis, EMG
Sees Patients at: UH Case Medical Center, UH Ahuja Medical Center, UH University Suburban Health Center
Marek A. Buczek, MD, PhDOffice Phone: 440-250-5303Appointment Phone: 216-250-5303
Special Interests: General Neurology, Electrophysiology, Headache, Chronic Pain Syndromes, EMG, Head Injury
Sees Patients at: UH Case Medical Center, UH Westlake Health Center, St. John Medical Center
All National Institute of Health (NIH) funding for basic and clinical research is awarded to the School of Medicine at Case Western Reserve University.
Brian Dyko, NPOffice Phone: 216-844-3495Appointment Phone: 216-844-3192
Special Interests: Autonomic Disorders, General Neurology, Headache, Memory & Cognition, Neuromuscular
Sees patients at: UH Case Medical Center, UH Westlake Health Center, UH Foley ElderHealth Center
Mary Jo Elmo, CNPOffice Phone: 216-844-8594
Special Interest: Diaphragm Pacing System Referral
Sees Patients at: UH Case Medical Center
Gerald E. Grossman, MDOffice Phone: 216-844-8925Appointment Phone: 216-844-2724
Special Interests: Neuromuscular Disorders, EMG
Sees Patients at: UH Case Medical Center, UH Ahuja Medical Center
Jeff Janata, PhDOffice Phone: 216-844-8550Appointment Phone: 216-844-8550
Special Interests: Autonomic Disorders, Behavior Therapy, Behavioral Medicine, Cognitive Behavioral Psychotherapy, Health Psychiatry, Health Psychology, Pain Management
Sees Patients at: UH MacDonald Women’s Hospital, W.O. Walker Center
Joseph A. Locala, MDOffice Phone: 216-844-2400Appointment Phone: 216-844-2400
Special Interests: Adult Psychiatry, Psychosomatic Psychiatry, Psychiatric Care of Medically Ill Patients, Transplant Psychiatry, Mood Disorders in the Medically Ill, Anxiety Disorders in the Medically Ill
Sees Patients at: UH Case Medical Center, UH Seidman Cancer Center, W.O. Walker Center
Daniel W. Miller, MDOffice Phone: 216-844-7380Appointment Phone: 216-844-3192
Special Interests: General Neurology, Neuromuscular Disorders, Neurophysiology, EMG
Sees Patients at: UH Case Medical Center, UH University Suburban Health Center
Raymond P. Onders, MDOffice Phone: 216-844-5797Appointment Phone: 216-844-7874
Special Interests: Minimally Invasive Surgery, General Surgery, Diaphragm Pacing, Anti-Reflux Surgery
Sees Patients at: UH Case Medical Center, UH University Suburban Health Center, UH Westlake Health Center
David C. Preston, MDOffice Phone: 216-844-7776Appointment Phone: 216-844-2724
Special Interests: Neuromuscular Disorders, Electrophysiology, Myasthenia Gravis, EMG, Entrapment Neuropathies, Peripheral Neuropathies, Peripheral Nerve Disorders
Sees Patients at: UH Case Medical Center, UH University Suburban Health Center, UH Richmond Medical Center
Jenice Robinson, MDOffice Phone: 216-844-3495Appointment Phone: 216-844-2724
Special Interests: Amyotrophic Lateral Sclerosis (ALS), Autonomic Disorders, Neuromuscular Disorders, Electromyography
Sees Patients at: UH Case Medical Center, UH Ahuja Medical Center
Barbara E. Shapiro, MD, PhDOffice Phone: 216-844-7768Appointment Phone: 216-844-2724
Special Interests: Lysosomal Disorders, EMG, Tay-Sachs Disease, Peripheral Neuropathy, Metabolic & Muscular Dystrophy, Neuromuscular Disorders
Sees Patients at: UH Case Medical Center, UH Ahuja Medical Center
Leonard Weinberger, MDOffice Phone: 440-357-3100Appointment Phone: 440-357-3100
Special Interests: General Neurology, Parkinson’s Disease, EMG
Sees Patients at: UH Concord Health Center
NEUROMUSCULAR CENTER
UHhospitals.org/Neuro • UH Neurological Institute | 3736 | University Hospitals • 216-844-2724
NEUROPSYCHIATRY CENTER
UH Neurological Institute’s Neuropsychiatry Center treats
co-occurring disorders in adults and pediatric patients.
This cross-functional treatment plan works for psychiatric
syndromes ranging from adjustment disorders, to depression
or anxiety, to a primary medical illness or to an underlying
mood or anxiety disorder that was previously unrecognized
or untreated. Primary services are available at our
community-based UH Richmond Medical Center.
Minimally invasive and nonsurgical solutionsTreatment refractory disorders may also be helped by the most advanced neuro-stimulation techniques, including:
• Electroconvulsive Therapy (ECT): External electrical stimulation of the brain to induce controlled seizure activity to treat refractory depression
Conditions treated:• Mood and anxiety disorders
• Drug and alcohol addiction recovery
• Delirium, dementia and psychiatric disorders of aging
• Psychiatric sequellae of neurologic conditions
InnovationsThe Neuropsychiatry Center is nationally renowned for pioneering advanced protocols for treatment refractory disorders, or disorders that are resistant to traditional therapy.
Patients may have access to pharmacologic treatments currently under investigation through research protocols of UH Case Medical Center National Institute of Mental Health “Bipolar Disorder Across the Lifespan” Center, the first funded Bipolar Center of Excellence in the United States.
Current clinical trialsPatients in our programs benefit through access to novel antipsychotic medications, antidepressants and various mood stabilizers that are generally not available. Following is an abbreviated list of current trials:
• Patients diagnosed with major depression or bipolar disorder may benefit from participation in an ongoing research study being conducted within the Mood & Metabolic Clinic. We are currently enrolling participants in a National Institutes of Health (NIH)-sponsored research project to test whether the treatment of insulin resistance can reduce symptoms of depression. Patients with obesity or those who have not responded to traditional antidepressant medications are encouraged to participate.
• Longitudinal Assessment of Mania Symptoms (LAMS) – An epidemiological based study that assesses symptoms of mania every six months for a five-year period.
• Collaborative Lithium Trial (COLT) – A multiphase study designed to assess the safety and efficacy of Lithium in children and adolescents with Bipolar I disorder.
For more information on available clinical trials call 216-844-2865 or visit UHhospitals.org/neuro/clinicaltrials
Programs:• Addiction Recovery Services: The Neuropsychiatry Center
houses an addiction recovery program at the W.O. Walker Center. Here, patients can be treated on an intensive outpatient basis where they come to the center three to five days a week and return home in the evening. Treatment includes an innovative concept of a UH unique 12-Step Program for patients suffering from both a mental illness and an addiction problem.
• Connor Integrative Medicine Network: This program offers a unique approach to healing and well-being that blends evidence-based, holistic therapies like acupuncture, massage, yoga and Reiki with traditional medicine to promote optimal health of the mind, body and spirit.
• Neuro-geriatric Program: Provides comprehensive inpatient and outpatient assessment and treatment for older adults with psychiatric illness or adults with psychiatric illness and co-occurring medical or neurological illness.
• Discovery & Wellness Center for Children: Our mission is to compassionately conduct clinically meaningful research that will better the lives of children and adolescents suffering from psychiatric illnesses. Research-based treatment programs are currently available for children and adolescents who suffer from problems such as schizophrenia, bipolar disorder, adult and childhood ADHD and disruptive behavior disorders and depression. All of these programs are provided at NO cost to the family.
• Mood & Metabolic Clinic (MMC): Developed out of the recognition that depressive disorders frequently co-occur with illnesses affecting the body’s metabolism. This program delivers personalized outpatient care to patients with mood disorders and co-occurring “metabolic” illnesses such as obesity, prediabetes and the metabolic syndrome.
• Consultation Psychiatry/Psychosomatic Medicine: The Division of Psychiatry and Medicine is a newly formed addition to the University Hospitals Department of Psychiatry, and offers comprehensive psychiatric care for patients with significant co-occurring medical illnesses in both outpatient and inpatient settings. Our primary goal is to foster a multidisciplinary team approach and to recognize the importance of the mind-body connection in patient care. Current sections of the division include: Emergency Department-UH Case Medical Center, Transplant Service, Psycho-Oncology and Dermatology.
All National Institute of Mental Health (NIMH) funding for basic and clinical research is awarded to the School of Medicine at Case Western Reserve University.
Robert J. Ronis, MD, MPHOffice Phone: 216-844-3883Appointment Phone: 216-844-3883
Special Interests: Community Psychiatry, Adult Ambulatory, Psychopharmacology, Chemical Dependency, Psychotherapy, Addiction Psychiatry, Community Mental Health
Sees Patients at: W.O. Walker Center
Joseph A. Locala, MDOffice Phone: 216-844-2400Appointment Phone: 216-844-2400
Special Interests: Adult Psychiatry, Psychosomatic Psychiatry, Psychiatric Care of Medically Ill Patients, Transplant Psychiatry, Mood Disorders in the Medically Ill, Anxiety Disorders in the Medically Ill
Sees Patients at: UH Case Medical Center, W.O. Walker Center
Francoise Adan, MDOffice Phone: 216-285-4070Appointment Phone: 216-285-4070
Special Interests: Integrative Psychiatry, Mood and Anxiety Disorders, Pharmacotherapy and Psychotherapy
Sees Patients at: UH Ahuja Medical Center
Felipe Amunategui, PhDOffice Phone: 216-844-3881Appointment Phone: 1-866-UH4-CARE
Special Interests: Cognitive Behavior Therapy, Adolescent Co-Morbid Disorders, Treatment Refractory Disorders, Child-Onset Mood and Anxiety Disorders, Disruptive Behavior Disorders, Parent-Child Relationship Problems, Psychotherapy, Psychotherapy Process Research, Graduate Education/Training, School/Community Consultation, Program Design/Evaluation, Self-Producing Systems
Sees Patients at: W.O. Walker Center
Christopher Bedosky, PhDOffice Phone: 216-844-8550Appointment Phone: 1-866-UH4-CARE
Special Interests: Child Adolescent and Adult Psychotherapy and Psychological Testing, Disruptive Behavioral Disorders
Sees Patients at: W.O. Walker Center
Philipp L. Dines, MD, PhDOffice Phone: 216-844-2400Appointment Phone: 216-844-2400
Special Interests: Adult Psychiatry, ECT, Geropsychiatry, Forensic Psychiatry, Geriatric Mood Disorders, Geriatric Psychotic Disorders, Dementia, Brain Injury, Mental Retardation, Psychiatric Issues in Neurological and Medical Primary Illnesses
Sees Patients at: UH Foley ElderHealth Center, W.O. Walker Center, UH Westlake Health Center
Keming Gao, MD, PhDOffice Phone: 216-844-2400Appointment Phone: 216-844-2400
Special Interests: Adult Psychiatry, Anxiety Disorders, Bipolar Disorders Research, ECT, Moods, Phenomenology and Psychopharmacotherapy
Sees Patients at: W.O. Walker Center
John Hertzer, MDOffice Phone: 216-844-3881Appointment Phone: 216-844-3881
Special Interests: Child Psychiatry, Adolescent Psychiatry, Psychopharmacology for Kids
Sees Patients at: W.O. Walker Center
Jeff Janata, PhDOffice Phone: 216-844-8550Appointment Phone: 216-844-8550
Special Interests: Autonomic Disorders, Behavior Therapy, Behavioral Medicine, Cognitive Behavioral Psychotherapy, Health Psychiatry, Health Psychology, Pain Management
Sees Patients at: UH MacDonald Women’s Hospital,W.O. Walker Center
Irina Korobkova, MDOffice Phone: 216-844-8726Appointment Phone: 216-844-2400
Special Interests: Dementia, ECT, Geriatric Psychiatry, Geropsychiatry
Sees Patients at: W.O. Walker Center,UH Richmond Medical Center
Jeanne Lackamp, MDOffice Phone: 216-844-2400Appointment Phone: 216-844-2400
Special Interests: Adult Psychiatry, Consultation, Medical Education
Sees Patients at: UH Case Medical Center, W.O. Walker Center
Zinaida Lebedeva, MDOffice Phone: 440-285-6588Appointment Phone: 216-844-2400
Special Interests: Adult Psychiatry, Geriatric Psychiatry
Sees Patients at: UH Case Medical Center, UH Geauga Medical Center
NEUROPSYCHIATRY CENTER
UHhospitals.org/Neuro • UH Neurological Institute | 3938 | University Hospitals • 216-844-2724
NEUROPSYCHIATRY CENTER
Jennifer Levin, PhDOffice Phone: 216-844-2400Appointment Phone: 1-866-UH4-CARE
Special Interests: Cognitive Behavioral Therapy for the Treatment of Anxiety Disorders, Depression, Panic Disorder, OCD, Social Phobia, Generalized Anxiety Disorder, Behavioral Medicine (including management of chronic pain and chronic disease), Health Psychology
Sees Patients at: W.O. Walker Center
Molly McVoy, MDOffice Phone: 216-844-3881Appointment Phone: 1-866-UH4-CARE
Special Interests: Pediatric Mood Disorders, ADHD, Trauma-related Psychotherapy, Pediatric Anxiety Disorders, Psychopharmacology
Sees Patients at: W.O. Walker Center
Susan Padrino, MDOffice Phone: 216-844-3400Appointment Phone: 216-844-3400
Special Interests: Adult Psychiatry, Community Psychiatry, Internal Medicine, Resident Education, Medical Student Education, Physical Diagnosis, Direct Observation, Family Therapy, Residency Education
Sees Patients at: UH Case Medical Center, UH Seidman Cancer Center
Stefani Parrisbalogun, MDOffice Phone: 216-983-5650Appointment Phone: 216-983-5650
Special Interests: Adult Psychiatry, Psychiatric Care of Medically Ill Patients, Psychosomatic Medicine, Emergency Psychiatry, HIV/AIDS Psychiatry, Bariatric Psychiatry
Sees Patients at: W.O. Walker Center, UH Seidman Cancer Center
Amir Poreh, PhDOffice Phone: 216-983-3126Appointment Phone: 1-866-UH4-CARE
Special Interests: Psychology, Neuropsychological Assessment
Sees Patients at: W.O. Walker Center
Stephen Ruedrich, MDOffice Phone: 216-983-3088Appointment Phone: 216-983-3088
Special Interests: Intellectual and Developmental Disabilities
Sees Patients at: W.O. Walker Center
Martha Sajatovic, MDOffice Phone: 216-844-2400Appointment Phone: 216-844-2400
Special Interests: Adult Psychiatry, Geropsychiatry, Geriatric Psychiatry, Health Services, Bipolar Disorder
Sees Patients at: W.O. Walker Center
Rebecca R. Schlachet, DOOffice Phone: 216-844-2400Appointment Phone: 216-844-2400
Special Interests: Adult Psychiatry, Geriatric Psychiatry
Sees Patients at: W.O. Walker Center
Binit Shah, MDOffice Phone: 216-844-3771Appointment Phone: 216-844-3771
Special Interests: Psycho-Oncology, Chronic Pain, Pain Rehabilitation
Sees Patients at: UH Case Medical Center, UH Seidman Cancer Center, W.O. Walker Center
Karen Tien, PhDOffice Phone: 216-844-6015Appointment Phone: 216-844-6015
Special Interests: Child & Adolescent Psychology, Child Chronic Illness & Injury, Cognitive Behavioral Therapy, Parenting, Pediatric Injury, Psychological Adjustment Problems, Health Promotion, Cognitive-Behavioral Therapy
Sees Patients at: W.O. Walker Center
Solomon Zaraa, DOOffice Phone: 216-983-3718Appointment Phone: 216-983-3718
Special Interests: Child Psychiatry, Bipolar Disorder, ADHD, Depression in Children and Adolescents
Sees Patients at: UH Case Medical Center, UH Seidman Cancer Center, W.O. Walker Center
UH Neurological Institute’s Neuroscience Nursing Practice
Center is dedicated to the development and implementation
of best practices in neuroscience nursing. Our mission is to
improve patients’ long-term outcomes by providing care
according to the most advanced protocols based on the
latest research findings; offering highly personalized care;
and maximizing efficiencies during every stage of treatment.
These strategies are implemented throughout the
continuum of patient care from first diagnosis,
through treatment and follow-up.
Clinical practice is based on three core principals:
• Evidence-based nursing practice – bridges the gap between nursing research and clinical practice
• Patient-centered care – places responsibility for important aspects of self-care and monitoring in the patients’ hands by providing tools and support
• Relationship-based nursing – maintains a standard of excellence by relying on the principles of relationship-based nursing
Treatment from UH neuroscience nurses provides multidisciplinary services including rehabilitation, pharmacy, social work, nutrition and medical services. Patient-centered care also takes into consideration individual circumstances including lifestyle, family situations, cultural traditions, religious beliefs and other factors during care planning and implementation. Patients are able to contribute to important aspects of their care and healing, and are prepared with the tools and support needed to carry out this responsibility. In this way, patient-centered care can reduce unneeded and unwanted services as well as improve outcomes.
InnovationsThe Neuroscience Nursing Practice Center aims to bridge the gap between nursing research and clinical practice by creating mechanisms to facilitate the translation of information from evidence-based research to practice. In this way, we ensure critical, succinct, reasonable evaluation and application of research findings as they relate to point-of-care delivery.
• Preoperative Bundle for Neurosurgery: Nursing worked in collaboration with Neurosurgery and Infection Control to develop a presurgical regimen which is now used for the outpatient preoperative neurosurgery patients and also for inpatient neurosurgery patients going for surgery. This process includes screening patients for MRSA/MSSA and prophylactically treating with mupirocin as well as bathing the patient with an alcohol-based scrub. With the implementation of the presurgical bundle, the rate of postoperative infections has shown a decrease.
• External Ventricular Drain: Nurses in the Neuroscience Intensive Care Unit (NSU) developed a guideline to standardize care of external ventricular drains (EVD). The standardized guideline provides instruction for drain placement which includes giving prophylactic antibiotics prior to drain placement including nursing management of the drain as well as CSF sampling techniques. Data is being collected to evaluate the positive effect this guideline has on improved EVD management.
Current clinical trialsTo bridge the gap between nursing research and clinical practice, the center aims to put evidence-based research into practice. This ensures high-quality care backed by scientific nursing services.
The Neuroscience Nursing Practice Center, in collaboration with the Case Western Reserve University Frances Payne Bolton School of Nursing, is working on a quality improvement research project to standardize nursing care of external ventricular drainage systems to decrease infection rates.
NEUROSCIENCE NURSING PRACTICE CENTER
Erin Supan, RNDirector, Neuroscience Nursing Practice Center Office Phone: 216-844-2413
UHhospitals.org/Neuro • UH Neurological Institute | 4140 | University Hospitals • 216-844-2724
PARKINSON’S & MOVEMENT DISORDERS CENTER
UH Neurological Institute’s Parkinson’s & Movement
Disorders Center is comprised of a multidisciplinary
team of specialists that offer pharmaceutical therapy
and surgical management to treat the complex
implications of movement disorders.
Surgical solutions:• Functional and Restorative Neurosurgery: State-of-the-art Deep
Brain Stimulation (DBS) surgery, as well as comprehensive preoperative and postoperative care for patients undergoing DBS. Careful, fine-tuned programming of DBS stimulators, balanced with medical management, is provided on an ongoing basis.
• Deep Brain Stimulation (DBS) Program: Manages tremors, movement and walking problems via surgical implantation of electrodes in the brain and pulse generators in the upper chest just beneath the collarbones.
Minimally invasive and nonsurgical solutions:• Botulinum Toxin Therapy: Used to treat movement disorders,
spasticity, drooling, migraine and other indications
• Intrathecal Baclofen Therapy (IBT): Effective in treating chronic pain and spasticity
Conditions treated:• Parkinson’s disease
• Essential tremor
• Dystonia
• Huntington’s disease
Innovations:• First in North America to perform DBS of the thalamus to treat
symptoms of Tourette syndrome successfully.
• The first group worldwide to complete a prospective randomized double blinded trial of thalamic DBS for Tourette syndrome in a pilot clinical trial of five patients.
• Greatest experience in Ohio with botulinum toxin injections, and uses the procedure for the broadest range of neurological indications.
Programs:• Huntington’s Disease Interdisciplinary Clinic: Offers neurology,
psychiatry, social work and genetics evaluation to patients and their families. Prescreening examinations to patients’ adult family members are also available.
• Pediatric Neurosurgery: Our expert neurosurgeons are skilled in the latest approaches and use the latest technologies to provide customized surgical solutions to pediatric patients with a wide variety of neurological conditions.
Current clinical studies:• Establishment of a CTSC Parkinson’s Disease Phenotypic and
Genotypic Registry. The purpose of this research study is to establish a registry of people with Parkinson’s disease (PD) to examine the effects of genes on PD. Investigators will compare disease features in people with certain gene mutations associated with PD but without those mutations, attempting to identify any distinctive characteristics. Investigators will also try to determine how the mutations contribute to the damage done to nerve cells in PD.
• BrainGate2: Feasibility Study of an Intracortical Neural Interface System for Persons with Tetraplegia. Obtain preliminary device safety information and demonstrate proof of principle (feasibility of efficacy) of the ability of people with tetraplegia to control a computer cursor and other assistive devices with their thoughts. Prospective, open-label, feasibility study. Primary Endpoint: Safety: Sensor successfully implanted, not explanted for safety reasons during the one-year post-implant evaluation, and there are no device-related Serious Adverse Events which result in death or permanently increased disability during the one-year post-implant evaluation period.
• AM IMPAKT Study. A Phase 4, open-label, efficacy and safety study of APOKYN® for rapid and reliable improvement of motor symptoms in Parkinson’s disease subjects with delayed onset of levodopa (L dopa) action. This is a multicenter, multiple-treatment, open-label design, outpatient study to assess the effect of APOKYN treatment in rapid and reliable improvement of motor symptoms in Parkinson’s disease subjects suffering from delayed or unreliable onset of (L dopa) action.
• Functional Magnetic Resonance Imaging (fMRI) Investigations of the Pathophysiology and effects of Deep Brain Stimulation in Dystonia: This NIH-sponsored study aims to reveal changes in the integration of brain sensory and motor systems in patients with dystonia using advanced imaging techniques and to also use these techniques in patients undergoing Deep Brain Stimulation to understand how the integration of these systems change as dystonia improves. This information will lead to understanding into both the pathophysiology of dystonia, and the mechanism by which DBS produced its improvement. This may furthermore be used to advance the treatment of dystonia by improving the location or method by which DBS is delivered and through the development of new therapeutic approaches.
• Functional Magnetic Resonance Imaging (fMRI) Investigations of the Pathophysiology of Parkinson’s disease: This pilot study aims to understand brain network changes involved in changes in the handling and perception of proprioceptive information in patients with Parkinson’s disease. Information gained from this study may be used to develop functional markers for progression of Parkinson’s disease and may reveal the neural circuitry involved in the alterations of perception of scale in patients with Parkinson’s disease.
All National Institutes of Health funding for basic and clinical research is awarded to the School of Medicine at Case Western Reserve University.
Benjamin L. Walter, MDOffice Phone: 216-844-8285Appointment Phone: 216-844-2724
Special Interests: Dystonia, Tremors, Movement Disorders, Functional Magnetic Resonance Imaging (MRI), Mechanisms of Effect of DBS, Deep Brain Stimulation, Parkinson’s Disease
Sees Patients at: UH Case Medical Center, UH University Suburban Health Center, UH Medina Health Center, UH Westlake Health Center
Steven A. Gunzler, MDOffice Phone: 216-844-8685Appointment Phone: 216-844-2724
Special Interests: Ataxia, Neurology, Dystonia, Memory and Aging, Botulinum Toxin Injections, Movement Disorders, Dementia, Parkinson’s Disease, Huntington’s Disease, Tremors
Sees Patients at: UH Ahuja Medical Center, UH University Suburban Health Center, UH Foley ElderHealth Center
Camilla Kilbane, MDOffice Phone: 216-844-3192Appointment Phone: 216-844-2724
Special Interests: Movement Disorders, Neurology, Deep Brain Stimulation, Dystonia, Essential Tremor, Neurophysiology, Parkinson’s Disease, Functional Movement Disorders, Genetics, Huntington’s Disease, Tourette’s Syndrome, Tremors, Botulinum Toxin Injections, Myoclonus, Chorea, Tics
Sees Patients at: UH Case Medical Center,UH University Suburban Health Center, UH Westlake Health Center
Joseph A. Locala, MDOffice Phone: 216-844-2400Appointment Phone: 216-844-2400
Special Interests: Adult Psychiatry, Psychosomatic Psychiatry, Psychiatric Care of Medically Ill Patients, Transplant Psychiatry, Mood Disorders in the Medically Ill, Anxiety Disorders in the Medically Ill
Sees Patients at: UH Case Medical Center, UH Seidman Cancer Center, W.O. Walker Center
Jonathan Miller, MDOffice Phone: 216-844-3470Appointment Phone: 216-844-2724
Special Interest: Movement Disorders Surgery
Sees Patients at: UH Case Medical Center
Amy Stralka-Larson, NPOffice Phone: 216-844-8285Appointment Phone: 216-844-2724
Special Interest: Movement Disorders
Sees Patients at: UH Case Medical Center, UH Ahuja Medical Center
Ellen Walter, NPOffice Phone: 216-291-2021Appointment Phone: 216-844-2724
Special Interest: Movement
Sees Patients at: UH Case Medical Center
PARKINSON’S & MOVEMENT DISORDERS CENTER
UHhospitals.org/Neuro • UH Neurological Institute | 4342 | University Hospitals • 216-844-2724
UH Neurological Institute’s Spinal Neurosurgery Center offers
the most innovative and sophisticated surgical techniques
along with proven conventional methods to treat the full
range of spinal disorders. Our physicians are nationally
recognized for their expertise in minimally invasive spinal
surgery techniques and have taught numerous courses on
the subject around the country. Our emphasis is on the total
care of the patient, viewing their spinal problem as it affects
their whole person, not just the spine.
Surgical solutions:• Spinal decompression (laminectomy, discectomy)
• Minimally invasive surgery
• Microsurgery of the spinal cord
• Microvascular surgery
• Spinal implants
• Numerous fusion techniques
• Dynamic spinal stabilization
• Spinal cord and cauda equina
• Revision spine surgery
• Deformity correction
• Image guided surgery
Minimally invasive and nonsurgical solutions:• CyberKnife® Radiosurgery for spinal tumors
• Kyphoplasty
• X-stop device
Conditions treatedThe Spinal Neurosurgery Center fosters an interdisciplinary collaboration with pain medicine interventionalists, orthopaedic surgeons and physical therapists to develop treatment plans according to each patient’s individual needs. Conditions treated include:• Arthritis
• Degenerative disorders/aging of the spine
• Fractures
• Herniated discs
• Infections of the spine
• Injury, trauma to back, neck, spine or spinal cord
• Malignant and benign spinal tumors
• Chronic spinal pain
• Spinal cord compression
• Spinal deformities (scoliosis, kyphosis)
• Spinal stenosis
Special equipment:• CyberKnife® Radiosurgery
• Image guidance in spinal surgery for trauma (Iso-C)
• BrainLAB
Program:• Pediatric Neurosurgery: Our expert neurosurgeons are skilled in
the latest approaches and use the latest technologies to provide customized surgical solutions to pediatric patients with a wide variety of neurological conditions.
Current clinical trialsThe Spinal Neurosurgery Center is currently recruiting for the following:
• DuraSeal. This multicenter, nonrandomized, post-approval study with a prospective treatment arm and a retrospective control arm will further evaluate the rate of post-operative CSF leaks in subjects who undergo a spinal procedure and receive DuraSeal Spine Sealant for treatment of either an intentional or incidental opening of the dura as compared to control patients who receive other products and/or treatments to close the dura.
• Prospective, Randomized, Multicenter Clinical Study Comparing Axial Lumbar Interbody Fusion (AxiaLIF®) and Transforaminal Lumbar Interbody Fusion (TLIF) Spinal Procedures. The primary objective of the study is to demonstrate noninferiority between the axial lumbar interbody fusion procedure (AxiaLIF) and the transforaminal lumbar interbody fusion procedure (TLIF) by meeting the following primary and secondary study endpoints: Primary Endpoint – Efficacy: Fusion of the targeted vertebral bodies (L4-L5-S1 or L5-S1) will be assessed individually at 24 months as determined by Central Radiographic Reviewer’s (orthopaedic surgeon) interpretation of high resolution computed tomography (CT) Scan; Secondary Endpoints – Safety: Incidence of major device-related adverse events by 24 months, defined as those requiring revision surgery or a secondary operation, or events resulting in permanent disability or death; Clinical Effectiveness: A 20 percent decrease in back pain compared to baseline at 24 months as measured by the Visual Analog Scale (VAS) score; Clinical Effectiveness: A 20 percent decrease in disability at 24 months compared to baseline as measured by the Oswestry Disability Index (ODI). Additional evaluations will also be collected to measure specific health outcomes throughout the study, including but not limited to, operative measures, time to return to work and activity post-surgery and quality of life relative to baseline as measured by the SF-36® Health Survey.
SPINAL NEUROSURGERY CENTER
Mirza Baig, MDOffice Phone: 216-286-6486Appointment Phone: 1-866-UH4-CARE
Special Interests: Physical Medicine, Rehabilitation
Sees Patients at: UH Case Medical Center, UH Rehabilitation Hospital
Nicholas C. Bambakidis, MDOffice Phone: 216-844-8758Appointment Phone: 216-844-2724
Special Interests: Spine Surgery, Spinal Cord Tumors
Sees Patients at: UH Case Medical Center, UH Ahuja Medical Center
Stephen Fulop, MDOffice Phone: 440-816-2860Appointment Phone: 440-816-2860
Special Interests: Minimally Invasive Spinal Surgery, Navigated Spinal Surgery, Cervical Degenerative Disease
Sees Patients at: Southwest General Health Center
Rishi Goel, MDOffice Phone: 440-250-9133Appointment Phone: 440-250-9133
Special Interests: General Neurosurgery, Spine Surgery, Spinal Cord Tumors
Sees Patients at: Southwest General Health Center, St. John Medical Center
Seth Alan Hoffer, MDOffice Phone: 216-844-5744Appointment Phone: 216-844-2724
Special Interests: Spine Surgery, Spinal Cord Tumors
Sees Patients at: UH Case Medical Center, UH Richmond Medical Center, UH Bedford Medical Center
Roseanna Lechner, MDOffice Phone: 216-285-5131Appointment Phone: 216-844-2724
Special Interests: Spine Surgery, Degenerative and Developmental Disorders, Tumors, Trauma, Minimally Invasive Spine Surgery
Sees Patients at: UH Ahuja Medical Center, UH Geauga Medical Center, UH Twinsburg Health Center
Jonathan Miller, MDOffice Phone: 216-844-3470Appointment Phone: 216-844-2724
Special Interests: Pain Neurosurgery, Stereotatic & Functional Neurosurgery, Gamma Knife® Stereotactic Radiosurgery, Spine Surgery, Spinal Cord Tumors
Sees Patients at: UH Case Medical Center
Richard Rhiew, MDOffice Phone: 440-816-2860Appointment Phone: 440-816-2860
Special Interests: General Neurosurgery, Physiology, Functional Neurosurgery, Spine Surgery
Sees Patients at: Southwest General Health Center
Bhupinder Sawhny, MDOffice Phone: 440-891-8880Appointment Phone: 440-891-8880
Special Interest: Neurosurgery
Sees Patients at: Southwest General Health Center
Warren R. Selman, MDOffice Phone: 216-844-5745Appointment Phone: 216-844-2724
Special Interests: Spine Surgery, Spinal Cord Tumors
Sees Patients at: UH Case Medical Center
Jennifer Sweet, MDOffice Phone: 216-983-3334Appointment Phone: 216-844-2724
Special Interest: Epilepsy Surgery
Sees Patients at: UH Case Medical Center
SPINAL NEUROSURGERY CENTER
UHhospitals.org/Neuro • UH Neurological Institute | 4544 | University Hospitals • 216-844-2724
TRAUMATIC BRAIN INJURY CENTER
Traumatic brain injury (TBI) is a complex medical condition
requiring specialized care to ensure the best patient
outcome. The wide spectrum of injuries encompasses
everything from mild concussion to life-threatening swelling
and bleeding. Despite this broad range of injury severity,
even the mildest injuries can have long-lasting effects.
The Traumatic Brain Injury Center within UH Neurological
Institute is a comprehensive, multidisciplinary, longitudinal
program that addresses all aspects of TBI. From the
emergency room to the intensive care unit to rehabilitation,
our experts deliver leading-edge care so that our patients can
regain the physical and cognitive functions that allow them
to recover from brain trauma.
Conditions treated:• Traumatic brain injury
• Mild traumatic brain injury
• Concussion
• Cerebral contusion
• Post-traumatic intracranial hypertension
• Post-traumatic cerebral herniation
• Skull fracture
• Epidural hematoma
• Subdural hematoma
• Penetrating head injury
• Post-traumatic CSF leak (otorrhea, rhinorrhea)
Special equipmentWe review minute-to-minute progress with the most advanced monitoring equipment in the world, including:
• Brain tissue oxygenation monitoring
• Cerebral blood flow monitoring
• Continuous video EEG monitoring
• CT angiography and CT perfusion studies
• Intracranial pressure monitoring
• MRI perfusion – diffusion imaging
• Positron emission tomography (PET)
• Transcranial doppler (TCD) ultrasonography
Inpatient Care of Acute TBIComprehensive inpatient care of the brain-injured patient requires the coordinated efforts of many specialists. At University Hospitals, we have put together a multidisciplinary group of physicians, nurses and therapists to address the needs of our patients and their families.
Our Beacon Award-winning Reinberger Neurosciences Intensive Care Unit (NSU) is the cornerstone of the care we deliver. This dedicated 14-bed ICU operates 24 hours a day under the supervision of neurosurgeons and critical care intensivists. Staffed by intensive care nurses who have completed specialized training in the care of patients with neurologic injuries, the NSU offers patients the most up-to-date technologies in brain physiology monitoring and treatment.
Focusing on early detection and rapid intervention to minimize and reverse the effects of brain trauma, our neurosurgeons are dedicated to giving patients their best chance of maintaining and recovering neurologic function.
Although brain and spinal injuries are the primary diagnoses of patients in the NSU, every organ system may be at risk. Fellowship-trained neurointensivists are on hand to treat the medical problems that may affect the heart, lungs and other organs.
Seth Alan Hoffer, MDOffice Phone: 216-844-5744Appointment Phone: 216-844-2724
Special Interests: Neurocritical Care, Spine Surgery, Traumatic Brain Injury
Sees Patients at: UH Case Medical Center, UH Richmond Medical Center, UH Bedford Medical Center
Mirza Baig, MDOffice Phone: 216-286-6486Appointment Phone: 1-866-UH4-CARE
Special Interests: Physical Medicine, Rehabilitation
Sees Patients at: UH Case Medical Center, UH Rehabilitation Hospital
Christopher Bailey, PhDOffice Phone: 216-844-3422Appointment Phone: 216-844-2724
Special Interests: Adult/Geriatric Neuropsychology, Alzheimer’s Disease, Attention Deficit/Hyperactivity Disorder (ADD/ADHD), Concussion, Dementia, Disability/Legal, Deep Brain Stimulation Surgery, Epilepsy and Epilepsy Surgery, Forensic Neuropsychology, Hydrocephalus, Memory Loss, Mild Cognitive Impairment, Neuropsychological Independent Medical Exam, Traumatic Brain Injury (TBI)
Sees Patients at: UH Case Medical Center, UH Ahuja Medical Center
Nicholas C. Bambakidis, MDOffice Phone: 216-844-8758Appointment Phone: 216-844-2724
Special Interests: Spinal Cord Injuries, Traumatic Brain Injury, Skull Base Surgery, Cerebrovascular Surgery
Sees Patients at: UH Case Medical Center, UH Ahuja Medical Center
Michael DeGeorgia, MDOffice Phone: 216-844-1552Appointment Phone: 216-844-2724
Special Interests: Critical Care Bioinformatics, Hemorrhagic Stroke, Hypothermia, ICU Monitoring, Ischemic Stroke, Neurocritical Care
Sees Patients at: UH Case Medical Center
Ciro Estabenez, MDOffice Phone: 216-844-3192
Appointment Phone: 216-844-2724
Special Interests: General Neurology, Neuromuscular
Disorders, Neurocritical Care, Stroke
Sees Patients at: UH Case Medical Center
TRAUMATIC BRAIN INJURY CENTER
Recognition and Rehabilitation After TBIPhysical and cognitive rehabilitation are essential to restore function following traumatic brain injury. Patients hospitalized at UH Case Medical Center may continue their comprehensive care at UH’s neurorehabilitation unit. This facility specializes in treating patients with brain injuries. With intensive therapies, patients are able to maximize their physical and mental abilities with the goal of returning to preinjury level of functioning.
While the brain is not able to regenerate itself as other organs can, the brain can often form new pathways following injury that facilitate recovery. Therapies overseen by neuropsychologists and rehabilitation physicians allow patients to retrain their minds and bodies.
Mild traumatic brain injuries such as concussion can go undetected – though their effects can have a profound impact upon the ability to perform at work or school, social functioning, and the prevalence of depression and anxiety. Our neuropsychologists are recognized for their advances in the detection and treatment of mild TBI, which is essential to patient recovery.
Our sports concussion team offers preseason baseline assessments to teams throughout Northeast Ohio to ensure that no student athletes return to their sport before they are ready. This combination of questionnaires and computerized tests measures a number of basic cognitive functions and is given before the season starts.
Future Directions in TBI Treatment Working in conjunction with Case Western Reserve University School of Medicine, University Hospitals’ basic science and translational research program for TBI examines the biology of brain injuries and is focused on developing therapies to protect and restore the brain. Collaborating with the National Institutes of Health, the Department of Defense and investigators around the globe, our team is studying the mechanisms of cell injury and death after brain trauma, the effects of TBI on cognition and behavior, and compounds that can be used to treat the injured brain.
While laboratory research is essential to medical progress, translating those discoveries into human treatments is a hallmark of our center as direct brain stimulation is used to help patients recover from brain injury. Stimulation by electrode implantation can retrain the brain to regain function lost by trauma.
UHhospitals.org/Neuro • UH Neurological Institute | 4746 | University Hospitals • 216-844-2724
Philip Fastenau, PhDOffice Phone: 216-844-3422Appointment Phone: 216-844-2724
Special Interests: Alzheimer’s Disease, Attention Deficit/Hyperactivity Disorder (ADD/ADHD), Concussion, Deep Brain Stimulation Surgery, Dementia, Epilepsy and Epilepsy Surgery, Hydrocephalus, Learning Disability (LD), Memory Loss, Mild Cognitive Impairment, Neuropsychological Test Development, Pediatric/Adult/Geriatric Neuropsychology, Traumatic Brain Injury (TBI)
Sees Patients at: UH Case Medical Center,UH Westlake Health Center
Cynthia Griggins, PhDOffice Phone: 216-844-1852Appointment Phone: 216-844-2724
Special Interests: ADHD and Learning Disabilities in Adults, Chronic Medical Conditions, Clinical Ethics, Cognitive Rehabilitation, Counseling and Therapy for Neurological Disorders, Dementia, Head Injury, Higher Cortical Functions, Language Mapping, Neuroethics, Neuropsychological Assessment of Adults and Adolescents, Stroke
Sees Patients at: UH Case Medical Center
Alan J. Lerner, MDOffice Phone: 216-464-6412Appointment Phone: 216-464-6445
Special Interests: Alzheimer’s Disease, Dementia, Behavioral Neurology, General Neurology, Higher Cortical Functions, Adult Attention Deficit Disorder (adult ADD/ADHD)
Sees Patients at: UH Ahuja Medical Center, UH Foley ElderHealth Center
James Mack, PhDOffice Phone: 216-844-3Special Interest: NeuropsychiatrySees Patients at: UH Rehabilitation Hospital
Jonathan Miller, MDOffice Phone: 216-844-3470Appointment Phone: 216-844-2724
Special Interests: Pain Neurosurgery, Movement Disorders Surgery, Facial Pain, Peripheral Nerve Surgery, Stereotatic and Functional Neurosurgery, Epilepsy Surgery, Gamma Knife® Stereotactic Radiosurgery
Sees Patients at: UH Case Medical Center
Warren R. Selman, MDOffice Phone: 216-844-5745Appointment Phone: 216-844-2724
Special Interests: Cerebrovascular Surgery, Spinal Cord Injuries, Traumatic Brain Injury, Skull Base Surgery
Sees Patients at: UH Case Medical Center
Crystal Tomei, MD, MPHOffice Phone: 216-844-5741Appointment Phone: 216-844-7337
Special Interests: Hydrocephalus, Pediatric Brain Tumors, Congenital Spinal Disorders and Spina Bifida, Tethered Cords, Craniosynostosis, Spasticity, Spinal Deformities, Pediatric Traumatic Brain Injury, Pediatric Spinal Injury
Sees Patients at: UH Rainbow Babies & Children’s Hospital
Todd Zeiger, MDOffice Phone: 330-239-4455Appointment Phone: 330-239-4455
Special Interests: Chronic Disease Management, FAA Exams, Sports Injuries
Sees patients at: Sharon Family Physicians
TRAUMATIC BRAIN INJURY CENTER
Name Specialty Page Office Phone
Adan, Francoise, MD Neuropsychiatry 37 216-844-2400
Amina, Shahram, MD Epilepsy 24 216-844-3675
Amunategui, Felipe, PhD Neuropsychiatry 37 216-844-3881
Andrefsky, John, MD Community Neurology 16 440-743-8120
Appleby, Brian, MD Brain Health & Memory 9 216-464-6445
Arafah, Baha, MD Brain Tumor & Neuro-Oncology 13 216-844-3142
Ashraf, Fareeha, MD Epilepsy 24 216-844-3192
Baig, Mirza, MD Functional & Restorative Neurosurgery, Spinal Neurosurgery, Traumatic Brain Injury 27, 43, 45 216-286-6486
Bailey, Christopher, PhD Brain Health & Memory, Traumatic Brain Injury 9, 45 216-844-3422
Bambakidis, Nicholas C., MD Brain Tumor & Neuro-Oncology, Comprehensive Stroke, Spinal Neurosurgery, Traumatic Brain Injury 13, 20, 43, 45 216-844-8758
Bardenstein, David, MD Brain Tumor & Neuro-Oncology 13 216-844-8686
Bedosky, Christopher, PhD Neuropsychiatry 37 216-844-8550
Buczek, Marek A., MD, PhD Community Neurology, Comprehensive Stroke, Neuromuscular 16, 20, 34 440-250-5303
Coffey, Michael, MD Brain Tumor & Neuro-Oncology 13 216-844-3061
Cohen, Mark L., MD Brain Tumor & Neuro-Oncology 13 216-844-8928
de Blank, Peter, MD, MS Brain Tumor & Neuro-Oncology 13 216-844-3345
Debrosse, Suzanne, MD Brain Health & Memory 9 216-844-3936
DeGeorgia, Michael A., MD Leadership, Comprehensive Stroke, Music & Medicine, Neurocritical Care, Traumatic Brain Injury 4, 20, 28, 31, 45 216-844-1552
Devereaux, Michael W., MD Community Neurology, Epilepsy 16, 24 216-844-3591
Dines, Philipp L., MD, PhD Neuropsychiatry 37 216-844-2400
Dupont, Stefan, MD, PhD Community Neurology, Comprehensive Stroke 16, 20 216-285-5041
Dyko, Brian, NP Neuromuscular 35 216-844-3495
Eccher, Matthew, MD, MSPH Epilepsy 24 216-844-1764
Elmo, Mary Jo, CNP Neuromuscular 35 216-844-8594
INDEX
UHhospitals.org/Neuro • UH Neurological Institute | 4948 | University Hospitals • 216-844-2724
INDEX
Name Specialty Page Office Phone
Estabenez, Ciro, MD Comprehensive Stroke, Neurocritical Care, Traumatic Brain Injury 20, 31, 45 216-844-3192
Fastenau, Philip, PhD Brain Health & Memory, Traumatic Brain Injury 9, 46 216-844-3422
Fulop , Stephen, MD Spinal Neurosurgery 43 440-816-2860
Furlan, Anthony J., MD Leadership, Comprehensive Stroke 4, 20 216-844-3193
Gao, Keming, MD, PhD Neuropsychiatry 37 216-844-2400
Gerson, Stanton, MD Brain Tumor & Neuro-Oncology 13 216-844-8562
Gibbons, Joseph, MD Brain Tumor & Neuro-Oncology 13 216-844-4735
Goel, Rishi, MD Spinal Neurosurgery 43 440-250-9133
Gold, Deborah, MD Brain Tumor & Neuro-Oncology 13 216-844-3691
Griggins, Cynthia, PhD Brain Health & Memory, Traumatic Brain Injury 9, 46 216-844-1852
Grossman, Gerald E., MD Neuromuscular 35 216-844-8925
Gunzler, Steven A., MD Brain Health & Memory, Parkinson’s & Movement Disorders 9, 41 216-844-8685
Hertzer, John, MD Neuropsychiatry 37 216-844-3272
Hoffer, Seth Alan, MD Leadership, Brain Tumor & Neuro-Oncology, Neurocritical Care, Spinal Neurosurgery, Traumatic Brain Injury 4, 13, 31, 43, 45 216-844-5744
Janata, Jeff, PhD Neuromuscular, Neuropsychiatry 35, 37 216-844-8550
Kahl, Rebecca Leadership 4 216-844-8598
Katirji, Bashar, MD Leadership, Functional & Restorative Neurosurgery, Neuromuscular 4, 27, 34 216-844-4854
Kilbane, Camilla, MD Parkinson’s & Movement Disorders 41 216-844-3192
Koon, Henry B., MD Brain Tumor & Neuro-Oncology 14 216-844-0120
Korobkova, Irina, MD Neuropsychiatry 37 216-844-8726
Kumar, Suresh, MD Community Neurology 17 440-816-6794
Lackamp, Jeanne, MD Neuropsychiatry 37 216-844-2400
Lang, Pamela, CNS Epilepsy 24 216-844-5383
Lanzieri, Charles, MD Brain Tumor & Neuro-Oncology 14 216-844-5721
Name Specialty Page Office Phone
Lass, Jonathan, MD Music & Medicine 28 216-844-8590
Lebedeva, Zinaida, MD Neuropsychiatry 37 440-285-6588
Lechner, Roseanna, MD Spinal Neurosurgery 43 216-285-5131
Lerner, Alan J., MD Leadership, Brain Health & Memory, Music & Medicine, Traumatic Brain Injury 4, 9, 28, 46 216-464-6412
Levin, Jennifer, PhD Neuropsychiatry 38 216-844-2400
Lhatoo, Samden, MD Leadership, Epilepsy, Functional & Restorative Neurosurgery 4, 24, 27 216-844-5855
Lo, Simon, MD Brain Tumor & Neuro-Oncology 14 216-844-3103
Locala, Joseph A., MD Leadership, Brain Tumor & Neuro-Oncology, Epilepsy, Neuromuscular, Neuropsychiatry, Parkinson’s & Movement Disorders
4, 14, 24, 35, 37, 41 216-844-2400
Lüders, Hans O., MD, PhD Epilepsy, Music & Medicine 24, 28 216-844-3650
Lyons, Janice A., MD Brain Tumor & Neuro-Oncology 14 216-844-2536
Machtay, Mitchell, MD Brain Tumor & Neuro-Oncology 14 216-844-2530
Mack, James, PhD Brain Health & Memory, Traumatic Brain Injury 9, 46 216-844-3188
Maronian, Nichole, MD Music & Medicine 29 216-983-3455
McVoy, Molly, MD Neuropsychiatry 38 216-844-3881
Megerian, Cliff A., MD Brain Tumor & Neuro-Oncology, Music & Medicine 14, 29 216-844-5500
Miller, Daniel W., MD Community Neurology, Comprehensive Stroke, Neuromuscular 17, 20, 35 216-844-7380
Miller, Jonathan, MDLeadership, Brain Tumor & Neuro-Oncology, Epilepsy, Functional & Restorative Neurosurgery, Music & Medicine, Parkinson’s & Movement Disorders, Spinal Neurosurgery, Traumatic Brain Injury
4, 14, 24, 25, 27, 29, 41, 43, 46 216-844-3470
Murray, Gail, PhD, MEd Music & Medicine 29 216-844-8168
Nock, Charles, MD Brain Tumor & Neuro-Oncology 14 216-844-3682
Ogrocki, Paula K., PhD Brain Health & Memory 9 216-464-6412
Onders, Raymond P., MD Neuromuscular 35 216-844-5797
Padrino, Susan, MD Brain Tumor & Neuro-Oncology, Neuropsychiatry 14, 38 216-844-3400
Park, Jun, MD Epilepsy 25 216-286-6644
Parrisbalogun, Stefani, MD Brain Tumor & Neuro-Oncology, Neuropsychiatry 15, 38 216-983-5650,
INDEX
UHhospitals.org/Neuro • UH Neurological Institute | 5150 | University Hospitals • 216-844-2724
INDEX
Name Specialty Page Office Phone
Poreh, Amir, PhD Neuropsychiatry 38 216-983-3126
Preston, David C., MD Music & Medicine, Neuromuscular 29, 35 216-844-7776
Ravishankar, Kempsagar, MD Community Neurology 17 440-826-9221
Rhiew, Richard, MD Spinal Neurosurgery 43 440-816-2860
Robinson, Jenice, MD Neuromuscular 35 216-844-3495
Rodgers, Mark, MD Brain Tumor & Neuro-Oncology 15 216-844-3478
Rogers, Lisa, DO Brain Tumor & Neuro-Oncology 15 216-844-3717
Ronis, Robert J., MD Leadership, Music & Medicine, Neuropsychiatry 4, 29, 37 216-844-3883
Rorick, Mark, MD Community Neurology, Comprehensive Stroke 17, 20 440-285-2888
Ruedrich, Stephen, MD Neuropsychiatry 38 216-983-3088
Ryan, David, MD Functional & Restorative Neurosurgery 27 440-816-2850
Sajatovic, Martha, MD Leadership, Neurological & Behavioral Outcomes, Neuropsychiatry 4, 32, 38 216-844-2808 216-368-7572
Sawhny, Bhupinder, MD Spinal Neurosurgery 43 440-891-8880
Schilz, Robert, DO, PhD Music & Medicine 29 216-844-3201
Schlachet, Rebecca R., DO Neuropsychiatry 38 216-844-2400
Selman, Warren R., MD Leadership, Brain Tumor & Neuro-Oncology, Comprehensive Stroke, Spinal Neurosurgery, Traumatic Brain Injury 4, 15, 20, 43, 46 216-844-5745
Semaan, Maroun, MD Music & Medicine 29 216-844-8013
Serra, Alessandro, MD, PhD Community Neurology 17 216-844-3193
Shah, Binit, MD Brain Tumor & Neuro-Oncology, Neuropsychiatry 15, 38 216-844-3771
Shahid, Asim, MD Epilepsy, Functional & Restorative Neurosurgery 25, 27 216-286-3691
Shapiro, Barbara E., MD, PhD Functional & Restorative Neurosurgery, Music & Medicine, Neuromuscular 27, 29, 35 216-844-7768
Sila, Cathy A., MD Leadership, Comprehensive Stroke 4, 20 216-844-8934
Silverman, Paula, MD Brain Tumor & Neuro-Oncology 15 216-844-8510
Sloan, Andrew E., MD Leadership, Brain Tumor & Neuro-Oncology 4, 13 216-844-6054
INDEX
Name Specialty Page Office Phone
Stearns, Duncan, MD Brain Tumor & Neuro-Oncology 15 216-844-7400
Stralka-Larson, Amy, NP Parkinson’s & Movement Disorders 41 216-844-8285
Sundararajan, Sophia, MD Comprehensive Stroke 21 216-844-8421
Sunshine, Jeffrey L., MD, PhD Brain Tumor & Neuro-Oncology, Comprehensive Stroke 15, 21 216-844-3112
Supan, Erin, RN Leadership, Neuroscience Nursing Practice 4, 39 216-844-2413
Sweet, Jennifer, MD Epilepsy, Functional & Restorative Neurosurgery, Spinal Neurosurgery 24, 27, 43 216-983-3334
Syed, Tanvir U., MD Community Neurology, Comprehensive Stroke, Epilepsy 17, 21, 24 440-827-5061
Tangen, Rachel B., PhD Epilepsy 25 216-844-3230
Tani, Marie, MD Community Neurology 17 440-357-3100
Tarr, Robert W., MD Leadership, Comprehensive Stroke 4, 21 216-844-5722
Tien, Karen J., PhD Neuropsychiatry 38 216-844-6015
Tomcik, Colleen B., MD Community Neurology, Comprehensive Stroke 17, 21 440-735-4723
Tomei, Krystal, MD, MPH Brain Tumor & Neuro-Oncology, Traumatic Brain Injury 15, 46 216-844-5741
Walker, Mark, MD Community Neurology, Comprehensive Stroke 17, 21 216-286-0315
Walter, Benjamin L., MD Leadership, Functional & Restorative Neurosurgery, Music & Medicine, Parkinson’s & Movement Disorders 4, 27, 29, 41 216-844-8285
Walter, Ellen, NP Parkinson’s & Movement Disorders 41 216-291-2021
Weinberger, Leonard, MD Community Neurology, Neuromuscular 17, 35 440-357-3100
Winer, Norton A., MD Community Neurology, Comprehensive Stroke 17, 21 216-383-7850
Xiong, Wei, MD Comprehensive Stroke, Neurocritical Care 21, 31 216-844-0474
Zaraa, Solomon, MD Neuropsychiatry 38 216-983-3718
Zeiger, Todd, MD Traumatic Brain Injury 46 330-239-4455
UHhospitals.org/Neuro • UH Neurological Institute | 5352 | University Hospitals • 216-844-2724
UH Case Medical Center11100 Euclid AvenueCleveland, Ohio 44106216-844-2724
The UH Neurological Institute offers unparalleled access and availability through its hub at UH Case Medical
Center and an ever-growing network of community facilities. The continued expansion of neurology,
advanced neurodiagnostics and neurosurgical capabilities at our community medical and health centers
brings our expertise and personalized care closer to home to those in outlying areas of Northeast Ohio.
Each of our systemwide locations have access to treatment options using advanced technology, such as:
neurostimulators for movement disorders, invasive monitoring and magnetoencephalography for epilepsy,
epilepsy surgical options, minimally invasive spine surgery and artificial disc replacement, image guided
neurosurgery, and endovascular therapy. In addition, all sites have access to leading-edge Stereotactic
Radiosurgery services, including Gamma Knife® and CyberKnife® therapy.
UH Ahuja Medical CenterKathy Risman Pavilion1000 Auburn Road, Suite 200Beachwood, Ohio 44122216-285-5115
Bolwell Health Center11100 Euclid Avenue, Suite 3100Cleveland, Ohio 44106216-844-2724
UH Bedford Medical Center44 Blaine AvenueBedford, Ohio 44146440-735-4775
UH Concord Health Center7500 Auburn RoadConcord Township, Ohio 44077216-844-2724
UH Elyria Medical Center630 East River StreetElyria, Ohio 44035
UH Foley ElderHealth Center3619 Park East Drive, Suite 211Beachwood, Ohio 44122216-464-6445
UH Geauga Medical Center13207 Ravenna RoadChardon, Ohio 44204440-285-6000
UH Geneva Medical Center870 West Main Street Geneva, Ohio 44041 440-466-1141
UH Landerbrook Health Center5885 Landerbrook DriveMayfield Heights, Ohio 44124216-844-2724
UH Medina Health Center4001 Carrick DriveMedina, Ohio 44256216-844-2724
UH Mentor Health Center9000 Mentor Avenue Mentor, Ohio 44060216-844-2724
UH Parma Medical Center7007 Powers BoulevardParma, Ohio 44129440-743-3000
UH Rehabilitation Hospital23333 Harvard RoadBeachwood, Ohio 44122216-593-2200
UH Richmond Medical Center27100 Chardon RoadRichmond Heights, Ohio 44143440-585-6137
St. John Medical Center29000 Center Ridge RoadWestlake, Ohio 44145440-835-6160
Southwest General Health Center18697 Bagley RoadMiddleburg Heights, Ohio 44130440-816-5050
UH Twinsburg Health Center8819 Commons BoulevardTwinsburg, Ohio 44087216-844-2724
UH University Suburban Health Center1611 South Green RoadSouth Euclid, Ohio 44121216-844-2724
UH Westlake Health Center960 Clague RoadWestlake, Ohio 44145216-844-2724
W.O. Walker Center10524 Euclid Avenue Cleveland, OH 44106Adult: 216-844-2400Pediatric: 216-844-3881
Northeast Ohio Locations – Refer patients to any of the following UH community locations.
LOCATIONS FOR NEUROLOGICAL CARE AT UNIVERSITY HOSPITALSCLINICIANS AND SCIENTISTS AT UH CASE MEDICAL CENTER AND
CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE
Warren R. Selman, MDHarvey Huntington Brown, Jr., Professor and ChairDepartment of Neurological SurgeryUH Case Medical Center and Case Western Reserve University School of MedicineNeurosurgeon-in-Chief and DirectorUniversity Hospitals Neurological InstituteChief of Division of Pediatric Neurosurgery, UH Rainbow Babies & Children’s Hospital
Anthony J. Furlan, MDChairman, Department of NeurologyUH Case Medical Center and Case Western Reserve University School of MedicineCo-Director, University Hospitals Neurological InstituteGilbert W. Humphrey Professor and Chair, Case Western ReserveUniversity School of Medicine
Francoise Adan, MDInstructor
Shahram Amina, MDAssistant Professor
Felipe Amunategui, PhDAssociate Director, Child &Adolescent Residency TrainingAssociate Professor
John Andrefsky, MDClinical Assistant Professor
Brian Appleby, MDAssociate Professor
Baha M. Arafah, MDDivision Chief and Fellowship Program DirectorClinical & Molecular EndocrinologyProfessor of Medicine
Fareeha Ashraf, MDClinical Instructor
Mirza Baig, MDClinical Assistant Professor
Christopher M. Bailey, PhDAssistant Professor
Nicholas C. Bambakidis, MDDirector, Cerebrovascular & Skull Base SurgeryProfessor and Vice Chair for Clinical Affairs
David Bardenstein, MDDirector, Center for Oculoplastics & Neuro-ophthalmologyProfessor of Ophthalmology
Christopher Bedosky, PhDAssistant Professor
Marek A. Buczek, MD, PhDAssistant Professor
Michael Coffey, MDAssistant Professor
Mark Cohen, MDAssistant Professor
Peter de Blank, MD, MSAssistant Professor
Suzanne Debrosse, MDClinical Assistant Professor
Michael DeGeorgia, MDDirector, Music & Medicine and Neurocritical Care CentersMaxeen Stone and John A. FlowerChair in NeurologyProfessor
Michael W. Devereaux, MDProfessor
Philipp Dines, MDDirector, Inpatient Geropsychiatry ServicesDirector, Geropsychiatry FellowshipAssistant Professor
Stefan Dupont, MD, PhDClinical Assistant Professor
Matthew Eccher, MD, MSPHAssistant Professor
Ciro Estabenez, MDAssistant Professor
Philip Fastenau, PhDDirector, Clinical NeuropsychologyProfessor
Steven Fulop, MD, MSClinical Assistant Professor
Keming Gao, MDClinical Director, Mood DisordersProgramMedical Director, ECTAssociate Professor
Stanton L. Gerson, MDDirector, University Hospitals Seidman Cancer Centerat UH Case Medical CenterDirector, Case Comprehensive Cancer Center at CaseWestern Reserve UniversityShiverick Professor of Hematologic Oncology
Joseph Gibbons, MDAssistant Professor
Rishi Goel, MDAssistant Clinical Professor
Deborah Gold, MDAssistant Professor
Cynthia Griggins, PhDAssistant Professor
Gerald E. Grossman, MDAssistant Professor
Steven A. Gunzler, MDAssistant Professor
John Hertzer, MDInterim Chief, Assistant Professor
Seth Alan Hoffer, MDDirector, Traumatic Brain Injury Center Co-Director, Neurocritical Care Center, UH Case Medical CenterDirector, NeurotraumaAssistant Professor
Jeffrey Janata, PhDDirector, Behavioral Medicine ProgramAssociate Professor
Bashar Katirji, MDDirector, Neuromuscular CenterProfessor
Camilla Kilbane, MDAssistant Professor
Henry B. Koon, MDAssistant Professor
Irina Korobkova, MDSenior Instructor
Jeanne Lackamp, MDDirector, Medical Student EducationAssistant Professor
Charles Lanzieri, MDAssistant Professor
Jonathan H. Lass, MDCharles I Thomas Professor
Zinaida Lebedeva, MDClinical Senior Instructor
Roseanna Lechner, MDClinical Assistant Professor
Jennifer Levin, PhDAssistant Professor
Alan J. Lerner, MDDirector, Brain Health & Memory CenterChair for Memory and CognitionProfessor
Samden D. Lhatoo, MD, FRCPDirector, Epilepsy Center Professor
Simon S. Lo, MDAssociate Professor
Joseph Locala, MDDirector, Neuropsychiatry Center Psychiatry & Medicine, Division DirectorDirector, Psychiatry & MedicineFellowshipAssociate Professor
Hans Lüders, MD, PhDProfessor
Janice A. Lyons, MDAssociate Professor
Mitchell Machtay, MDVincent K. Smith Chair in Radiation OncologyProfessor
James Mack, PhDAssistant Professor
Nicole Maronian, MDDirector, Voice CenterAssociate Professor
Molly McVoy, MDDirector, Child & AdolescentResidency TrainingAssistant Professor
Cliff A. Megerian, MDChairman of Otolaryngology – Head & Neck SurgeryRichard W. and Patricia R. PogueChair in Auditory Surgery and Hearing SciencesPresident, UH Physician ServicesProfessor
Daniel W. Miller, MDAssistant Professor
Jonathan Miller, MDDirector, Functional & RestorativeNeurosurgery Center,UH Case Medical CenterGeorge R. and Constance P.Lincoln Master Clinician inMemory Loss and BehavioralOutcomesAssociate Professor
UHhospitals.org/Neuro • UH Neurological Institute | 5554 | University Hospitals • 216-844-2724
Gail S. Murray, MEd, PhD, CC-A, FAAAAssociate Professor
Charles J. Nock, MDAssistant Professor
Paula K. Ogrocki, PhDAssistant Professor
Raymond Onders, MDDirector, Adult Minimally Invasive SurgeryMargaret and Walter Remen Chair in Surgical Innovation Professor
Susan Padrino, MDAssistant Professor
Jun Park, MDClinical Assistant Professor
Stephani Parrisbalogun, MDSenior Instructor
Amir Poreh, PhDClinical Associate Professor
David C. Preston, MDProfessor and Vice ChairmanProgram Director, NeurologyResidency
Richard B. Rhiew, MD, PhDClinical Assistant Professor
Jenice Robinson, MDAssistant Professor
Mark Rodgers, MDAssistant Professor
Lisa R. Rogers, DODirector, Medical Neuro-OncologyProfessor
Robert J. Ronis, MD, MPHChairman, Department ofPsychiatry, UH Case Medical Center and Case Western Reserve UniversitySchool of MedicinePsychiatrist-In-Chief, University HospitalsDouglas Danford Bond Professor
Mark Rorick, MDDirector, Primary Stroke Center at UH Geauga Medical CenterClinical Associate Professor
Stephen Ruedrich, MDAdult Psychiatry, Division DirectorL. Douglas Lenkoski Professor
Martha Sajatovic, MDDirector, Neurological & Behavioral OutcomesCenter, Willard W. Brown Chair inNeurological OutcomesProfessor
Robert Schilz, DO, PhDDirector, Pulmonary VascularDisease and Lung TransplantationAssociate Professor
Rebecca Schlachet, DOSenior Instructor
Maroun Semaan, MDAssociate Director, Otology,Neurotology & Balance DisordersAssistant Professor
Alessandro Serra, MD, PhDAssistant Professor
Binit Shah, MDDirector, Psycho-Oncology ProgramSenior Instructor
Asim Shahid, MDAssistant Professor
Barbara E. Shapiro, MD, PhDDirector, Neuromuscular ResearchAssociate Professor
Cathy Sila, MDDirector, Comprehensive Stroke Center, George M. Humphrey IIChair in Neurology, Professor
Paula Silverman, MDAssociate Professor
Andrew E. Sloan, MDDirector, Brain Tumor & Neuro-Oncology CenterPeter D. Cristal Chair in NeurosurgeryVice Chair for Research Affairs and Professor
Duncan Stearns, MDAssistant Professor
Sophia Sundararajan, MD, PhDAssistant Professor
Jeffrey Sunshine, MD, PhDAssistant Professor
Jennifer Sweet, MDAssistant Professor
Tanvir U. Syed, MD, MPHAssistant Professor
Rachel Tangen, PhDAssistant Professor
Marie Tani, MDClinical Assistant Professor
Robert Tarr, MDAssociate Director, UH Neurological InstituteSection Chief NeuroradiologyProfessor
Karen Tien, PhDSenior Instructor
Colleen B. Tomcik, MDInstructor
Krystal Tomei, MD, MPHAssistant Professor
Mark F. Walker, MDAssociate Professor
Benjamin L. Walter, MDDirector, Movement Disorders Center Medical Director, Deep BrainStimulation (DBS) ProgramAssistant Professor
Leonard Weinberger, MDClinical Assistant Professor
Peter J. Whitehouse, MD, PhDProfessor
Norton Winer, MDClinical Assistant Professor
Wei Xiong, MDAssistant Professor
Solomon Zaraa, DOSenior Instructor
The commitment to exceptional patient care begins with revolutionary discovery. University Hospitals Case Medical Center is the primary affiliate of Case Western Reserve University School of Medicine, a national leader in medical research and education and consistently ranked among the top research medical schools in the country by U.S. News & World Report. Through their faculty appointments at Case Western Reserve University School of Medicine, physicians at UH Case Medical Center are advancing medical care through innovative research and discovery that bring the latest treatment options to patients.
Physicians receive their academic appointments and their accompanying titles from Case Western Reserve University School of Medicine.
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Among the nation’s leading academic medical centers, University Hospitals Case Medical Center is the primary affiliate of Case Western Reserve University School of Medicine, a nationally recognized leader in medical research and education.