2015 physician referral guide

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UH NEUROLOGICAL INSTITUTE 2015 PHYSICIAN REFERRAL GUIDE University Hospitals Case Medical Center is the primary affiliate of Case Western Reserve University School of Medicine

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Page 1: 2015 PHYSICIAN REFERRAL GUIDE

UH NEUROLOGICAL INSTITUTE

2015PHYSICIAN REFERRAL GUIDE

University Hospitals Case Medical Center is the primary affiliate of Case Western Reserve University School of Medicine

Page 2: 2015 PHYSICIAN REFERRAL GUIDE

UHhospitals.org/Neuro • UH Neurological Institute | 32 | University Hospitals • 216-844-2724

Through a dedicated multidisciplinary team of skilled specialists

with access to leading-edge technologies, facilities and

research, the institute delivers premier care for the full range

of neurological disorders. From minor management of

common disorders to the most advanced treatments

and surgeries, no case is too complex.

University Hospitals neuroscience specialists are available to

you as a resource for second opinions or to consult or operate

on complex diseases. By referring patients into the University

Hospitals Neurological Institute, you can count on unparalleled

communication keeping you informed on your patients’

progress, and returning them to your practice for ongoing

care and follow-up. With personalized treatment plans from

specialists in any of our 15 Centers of Excellence, patients may

also receive care from our nationally recognized colleagues at

University Hospitals Rainbow Babies & Children’s Hospital and

University Hospitals Seidman Cancer Center.

Centers of Excellence Include:Brain Health & Memory . . . . . . . . . . . . . . . . . . . . . . . . . 7

Brain Tumor & Neuro-Oncology . . . . . . . . . . . . . . . . . . 10

Community Neurology . . . . . . . . . . . . . . . . . . . . . . . . 16

Comprehensive Stroke . . . . . . . . . . . . . . . . . . . . . . . . 18

Epilepsy . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 22

Functional & Restorative Neurosurgery . . . . . . . . . . . . 26

Music & Medicine . . . . . . . . . . . . . . . . . . . . . . . . . . . . 28

Neurocritical Care . . . . . . . . . . . . . . . . . . . . . . . . . . . . 30

Neurological & Behavioral Outcomes . . . . . . . . . . . . . . 32

Neuromuscular . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 33

Neuropsychiatry . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 36

Neuroscience Nursing Practice . . . . . . . . . . . . . . . . . . . 39

Parkinson’s & Movement Disorders . . . . . . . . . . . . . . . 40

Spinal Neurosurgery . . . . . . . . . . . . . . . . . . . . . . . . . . 42

Traumatic Brain Injury . . . . . . . . . . . . . . . . . . . . . . . . . 44

Recognized by U.S. News & World Report

as one of the nation’s finest neuroscience

programs, University Hospitals

Neurological Institute is Northeast Ohio’s

first designated neurological institute

providing integrated and comprehensive

care for patients with diseases affecting

the nervous system. The institute

comprises 15 Centers of Excellence,

which bring together some of the

country’s foremost experts in neurology,

neurosurgery, neuroradiology,

neuro-oncology, neuro-ophthalmology,

neurotology, neuropathology,

neuropsychology, neuropsychiatry

and related specialties.

Adult Neurology and Neurosurgery ReferralsTo refer an adult patient, please call 216-844-2724

24/7 Transfers and Urgent ConsultationsFor quick, efficient transfers and 24/7 consultation with attending physicians, please call the UH Transfer Referral Center at 216-844-1111 or 1-800-421-9199

Physician Advice LineFor free advice from our nationally renowned neurosurgery specialists, please call 216-844-1001

Immediate Access AvailableThe UH Neurological Institute offers triage services and same-day/next-day availability for patients with urgent needs. When you call 216-844-2724 to refer a patient, please identify the level of urgency so that we can best accommodate you and your patient.

Same-Day EMG ServicesTo schedule a same-day EMG, please call 216-844-1923

Urgent Access or Concerns with Neurology and Neurosurgery Access8 a.m. – 5 p.m. M – F

Tracy Grushcrow Office: 216-844-3418Interim Practice Manager Page: 32393

All Other Times for Neurosurgery Access

Warren Selman, MD Office: 216-844-5745Chairman Page: 35047 Cell: 216-308-3035

Nicholas Bambakidis, MD Office: 216-844-8758Vice Chair Clinical Affairs Page: 37758 Cell: 216-339-4061

Pediatric Neurosurgery ReferralsTo refer a pediatric patient, please call 216-844-PEDS (216-844-7337)

Pediatric Advice LineFor advice from our leading pediatric specialists, please call 216-UH4-ADOC (216-844-2362)

PHYSICIAN RESOURCES

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Warren R. Selman, MDDirector, UH Neurological InstituteChairman, Department of Neurological Surgery Chief of Division of Pediatric Neurosurgery, UH Rainbow Babies & Children’s HospitalOffice Phone: 216-844-5745Appointment Phone: 216-844-2724

Anthony J. Furlan, MDCo-Director, UH Neurological InstituteChairman, Department of Neurology Office Phone: 216-844-3193Appointment Phone: 216-844-2724

Rebecca Kahl, MBAInterim Director, Neurological InstituteOffice Phone: 216-844-8598

Michael A. DeGeorgia, MDDirector, Music & Medicine and Neurocritical Care Centers Office Phone: 216-844-1552Appointment Phone: 216-844-2724

Seth Alan Hoffer, MDDirector, Traumatic Brain Injury CenterOffice Phone: 216-844-5744Appointment Phone: 216-844-2724

Bashar Katirji, MDDirector, Neuromuscular Center Office Phone: 216-844-4854Appointment Phone: 216-844-2724

Alan J. Lerner, MDDirector, Brain Health & Memory Center Office Phone: 216-464-6412Appointment Phone: 216-464-6445

Samden Lhatoo, MDDirector, Epilepsy CenterOffice Phone: 216-844-5855Appointment Phone: 216-844-2724

Joseph A. Locala, MDDirector, Neuropsychiatry CenterOffice Phone: 216-844-2400Appointment Phone: 216-844-2400

Jonathan Miller, MDDirector, Functional & Restorative Neurosurgery CenterOffice Phone: 216-844-3470

Robert J. Ronis, MD, MPHAssociate Director, UH Neurological InstituteChairman, Department of Psychiatry Office Phone: 216-844-3883Appointment Phone: 216-844-3883

Martha Sajatovic, MDDirector, Neurological & Behavioral Outcomes Center Office Phone: 216-368-7572, 216-844-2808Appointment Phone: 216-844-2400

Cathy A. Sila, MDDirector, Comprehensive Stroke Center Office Phone: 216-844-8934Appointment Phone: 216-844-2724

Andrew E. Sloan, MDDirector, Brain Tumor & Neuro-Oncology Center Office Phone: 216-844-6054Appointment Phone: 216-844-2724

Erin Supan, RNDirector, Neuroscience Nursing Practice Center Office Phone: 216-844-2413

Robert W. Tarr, MDAssociate Director, UH Neurological InstituteSection Chief, Department of Neuroradiology Office Phone: 216-844-5722

Benjamin Walter, MDDirector, Parkinson’s & Movement Disorders Center Office Phone: 216-844-8285Appointment Phone: 216-844-2724

LEADERSHIP

UH Case Medical Center is internationally renowned for its

innovations in healing and discovery. In addition to providing

state-of-the-art care for patients with neurological diseases,

the UH Neurological Institute educates medical students,

neurology residents and fellows in neurology subspecialties.

Nationally RecognizedThe University Hospitals Neurological Institute is nationally recognized as one of the premier neuroscience and neurosurgery programs in the country.

In 2014, U.S. News & World Report ranked UH Case Medical Center as one of the nation’s best neurology and neurosurgery programs.

Additionally, after studying multidisciplinary institutes at academic medical centers to describe their operations and assess their impact on performance, University HealthSystem Consortium (UHC) proclaimed the UH Neurological Institute model as the industry benchmark, calling it “a model of interdepartmental collaboration, enhancing value across the clinical, educational and research missions.”

Leading Innovations:• First in the world to test the diaphragm pacing stimulation system

on patients with amyotrophic lateral sclerosis (ALS)• First in North America to perform deep brain stimulation of the

thalamus to successfully treat symptoms of Tourette’s syndrome• One of only six hospital centers in the world experienced in using

AutoLITT for minimally invasive brain tumor surgery• First in Ohio to offer both Gamma Knife® and CyberKnife® in our

Stereotactic Radiosurgery suite• Neuroscience Intensive Care Unit is one of only 25 centers in the

nation offering fellowships in neurocritical care• One of Ohio’s first physician-led Brain Attack programs –

now one of the largest in the nation with 24/7 availability for emergency transfers

• One of only 25 centers in the United States offering surgical therapy for dystonia

• First comprehensive pediatric autonomic lab in the country• Only program in the United States that offers multiple

hippocampal transections for the treatment of epilepsy

National Recognitions:• UH Neurological Institute: Received the Gold Center of Excellence

recognition from NeuStrategy, Inc. for spine, neurovascular stroke, cranial tumor and neuromodulation neurosurgery.

• UH Case Medical Center: Recognized by Becker’s Hospital Review as one of the 100 Top Neurosurgery and Spine programs.

• UH Case Medical Center: Awarded Comprehensive Stroke Center Certification. This is the highest available designation from The Joint Commission.

• Certified Primary Stroke Center: Awarded to UH Ahuja Medical Center, UH Geauga Medical Center, UH Bedford and Richmond Medical Centers, campuses of UH Regional Hospitals, UH Parma Medical Center, St. John Medical Center and Southwest General Health Center.

• Epilepsy Center: Designated as a Level IV Epilepsy Center – the highest designation available – by the National Association of Epilepsy Centers. The Epilepsy Center also received accreditation for both its epilepsy and clinical neurophysiology fellowships.

• Annual Performance Achievement Award for Stroke: Awarded by the American Heart Association

• University Hospitals Case Medical Center, the only major teaching hospital in Ohio to be recognized by Thomson Reuters 100 Top Hospitals

• Beacon Award for Critical Care Excellence• Leapfrog Top 50 Hospitals• Magnet Status for Nursing

INNOVATIONS IN CARING

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Novel ResearchThe commitment to exceptional patient care begins with revolutionary discovery. University Hospitals Case Medical Center is the primary affiliate of Case Western Reserve University School of Medicine, a national leader in medical research and education and consistently ranked among the top research medical schools in the country by U.S. News & World Report. Through their faculty appointments at Case Western Reserve University School of Medicine, physicians at UH Case Medical Center are advancing medical care through innovative clinical research and discovery that bring the latest treatment options to patients.

University Hospitals Case Medical Center and the UH Neurological Institute offer a depth of care and scope of services that no other medical center in Ohio can deliver. As the primary affiliate of Case Western Reserve University School of Medicine, University Hospitals Case Medical Center has unparalleled access to top talent, emerging technologies and therapies, and unequaled clinical research resources.

All National Institutes of Health funding for basic and clinical research is awarded to the School of Medicine at Case Western Reserve University.

Physician Advice LineYou’re just one phone call away from some of the finest neurological specialists and surgeons in the country. Receive immediate decision-making advice from the UH Neurological Institute team of experts by calling 216-844-1001.

Physician CommunicationThe model for interaction with physicians who refer to the UH Neurological Institute emphasizes communication and mutual respect. We ensure continuity of care from referring physician to specialist by providing prompt communication after each patient visit and carefully coordinated perioperative management. To refer a patient, call 216-844-2724.

24-Hour Rapid ReferralCall 216-844-2724 and your patient will be scheduled within 24 hours for an appointment with one of our neurological specialists.

BRAIN HEALTH & MEMORY CENTER

UH Neurological Institute’s Brain Health & Memory

Center has internationally recognized experts who devote

themselves to caring not only for patients, but their families

too. Through an interdisciplinary and longitudinal approach,

treatment processes help maintain cognitive, physical

and emotional fitness, as well as a measure of stability

and reassurance. Programs for community and caregiver

education, quality of care giving and risk factors for memory

loss have been a center priority.

Conditions treated:• Alzheimer’s disease

• Mild cognitive impairment

• Frontotemporal dementia

• Parkinson’s disease dementia

• Dementia with Lewy bodies

• Adult Attention Deficit-Hyperactivity Disorder

• Trisomy 21 (Down syndrome)

• Vascular dementia

• Normal pressure hydrocephalus

• Huntington’s disease

• Creutzfeldt-Jakob disease

InnovationsThe Brain Health & Memory Center has established an interdisciplinary care model that has been adopted by neurological institutes nationwide. It has been a leader for research in Alzheimer’s disease and has contributed to studies of the natural history, genetics and behavioral aspects of Alzheimer’s disease.

Surgical solutions:• Ventriculo-Peritoneal Shunting – For individuals diagnosed with

normal pressure hydrocephalus.

Patients and their families benefit from staff expertise and resources in the following areas:

• Neurology • Pharmacy

• Geriatrics • Neuropsychiatry

• Social work • Neuropsychology

• Pathology • Geropsychiatry

• Nursing • Speech Pathology

• Radiology

Current clinical trialsOver the past two decades, our physicians have emerged as leaders in Alzheimer’s disease evaluation and genetic studies. Clinical trials are ongoing to determine the safety and efficacy of pharmaceutical alternatives, including:

Studies change frequently; the following are those we are currently recruiting for:

• The Alzheimer’s Disease Neuroimaging Initiative (ADNI). The purpose of this study is to build upon the information obtained in the original Alzheimer’s Disease Neuroimaging Initiative (ADNI1) and ADNI-GO (Grand Opportunity; a study funded through an NIH grant under the American Recovery and Reinvestment Act), to examine how brain imaging technology can be used with other tests to measure the progression of mild cognitive impairment (MCI) and early Alzheimer’s disease (AD). ADNI2 seeks to inform the neuroscience of AD. This information will aid in the early detection of AD, and in measuring the effectiveness of treatments in future clinical trials.

• Cataract removal and Alzheimer’s disease. The investigators have designed this study to determine whether or not cataract removal will improve the AD patient’s quality of life, vision and cognition.

• A Phase III double-blind, placebo-controlled, randomized, parallel group, 12-month safety and efficacy trial of Leuco-methylthioninium bis (hydromethanesulfonate) in subjects with Behavioral Variant Frontotemporal Dementia (bvFTD). This multinational study is currently open for enrollment. The primary object is to demonstrate the efficacy of LMTM as assessed by change from baseline on the Addenbrooke’s Cognitive Examination Revised (ACE-R) and the Modified Alzheimer’s Disease Cooperative Study – Clinical Global Impression of Change (Modified ADCS-CGIC) – independently rated.

• The A4 (Anti-Amyloid Treatment in Asymptomatic Alzheimer’s) Study. This will test whether the amyloid antibody called solanezumab can prevent or slow the progression of Alzheimer’s disease. Amyloid is a protein normally produced in the brain that can build up in older people, forming amyloid plaque deposits. Scientists believe this buildup of deposits may play a key role in the eventual development of Alzheimer’s disease-related memory loss. The A4 study will enroll older adults, age 65 to 85, who have normal thinking and memory function. Participants will be screened to determine if they have elevated levels of amyloid plaques in their brains detected through a PET imaging scan. The overall goal of the A4 study is to test whether decreasing amyloid in the brain can help slow the memory loss associated with amyloid buildup.

INNOVATIONS IN CARING

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BRAIN HEALTH & MEMORY CENTER

For a current list of clinical trials within the Brain Health & Memory Center, visit UHhospitals.org/trials/neuro/clinicaltrials.

• Longitudinal Evaluation of Amyloid Risk and Neurodegeneration (LEARN) Study. A companion study to Anti-Amyloid Treatment in Asymptomatic Alzheimer’s Disease (A4) Trial. This is a multicenter, observational study evaluating the rate of cognitive change in approximately 500 subjects without evidence of elevated Aß on screening PET scan. To characterize the longitudinal change on the cognitive, clinical and biomarker measures used in the A4 trial in Aßne individuals in comparison to the Aße A4 placebo arm individuals.

• Study of Nasal Insulin to Fight Forgetfulness (SNIFF). An 18-month clinical trial testing nasal insulin to treat early Alzheimer’s disease is at 30 research sites nationwide. The nasal insulin approach has shown promise in previous short-term clinical trials. It is hypothesized that after 12 months of treatment with intranasally administered insulin compared to placebo, participants will improve cognition, memory and daily function.

• The NOBLE study is a Phase-2 multicenter, randomized, double blind, placebo-controlled, parallel group study that will explore the potential of the investigational drug T-817MA, a neuroprotectant agent designed to protect against neuron loss. Neuroprotectants are used for many central nervous system disorders including stroke and Parkinson’s disease. The study will enroll 450 people with mild-to-moderate AD at research sites across the United States. Eligible candidates include women and men aged 55 to 85 years old with mild-to-moderate AD who have been taking donepezil (Aricept®) for at least six months prior to enrollment. The duration of treatment is about 14 months. The potential of T-817MA to modify the pace of the disease may positively impact quality of life in those who are currently suffering with mild-to-moderate AD as well as their caregivers. The study is sponsored by Toyama Chemical Co., Ltd, FUJIFILM Group, and is being conducted by the Alzheimer’s Disease Cooperative Study (ADCS).

• Apathy in Dementia Methylphenidate Trial 2 (ADMET 2) is a Phase III, placebo-controlled, masked, six-month, 10-center randomized clinical trial sponsored by the National Institute of Aging involving 200 participants with Alzheimer’s disease. ADMET 2 is designed to examine the efficacy and safety of methylphenidate as treatment for clinically significant apathy in AD participants. ADMET 2 will enroll participants from real-world settings such as outpatient, nursing home and assisted-living facilities and will examine the effects of methylphenidate on apathy and cognition. ADMET 2 will also conduct careful safety monitoring.

ProgramsOur center coordinates with primary care physicians to go beyond treating biological issues by offering specialty services, such as:

• Alzheimer’s Disease & Memory Disorders Program: Evaluates and treats individuals with Alzheimer’s disease and related dementia syndromes. Services include traditional medical treatments and state-of-the-art clinical research programs.

• Memory Health Program: Targets individuals with concerns about maintaining brain health. The program offers a variety of services related to maintaining cognitive wellness in the context of aging.

• Sports Concussion Program: Evaluation of the severity and consequences of sports concussion in athletes, including assessment of safety for return to play and indicators of prognosis from head injury.

• Huntington’s Disease Interdisciplinary Clinic: Offers neurology, psychiatry, social work and genetics evaluation to patients and their families. Prescreening examinations to patients’ adult family members are also available.

• Prion Disease Program: Prion diseases are a group of rapidly progressive neurodegenerative conditions that are caused by an abnormal form of the prion protein. Sporadic Creutzfeldt-Jakob disease (sCJD) is the most common prion disease and is caused by a spontaneous change in the normal prion protein. UH physician Brian Appleby, MD, serves as Co-Director of the National Prion Disease Pathology Surveillance Center and is a Member of the CJD Foundation’s Board of Directors, and his primary research and clinical interest is prion disease.

Alan J. Lerner, MDOffice Phone: 216-464-6412Appointment Phone: 216-464-6445

Special Interests: Alzheimer’s Disease, Dementia, Behavioral Neurology, General Neurology, Higher Cortical Functions, Adult Attention Deficit Disorder (adult ADD/ADHD), Frontotemporal Dementia

Sees Patients at: UH Ahuja Medical Center, UH Foley ElderHealth Center

Brian Appleby, MDOffice Phone: 216-464-6445Appointment Phone: 216-844-2724

Special Interests: Neurology, Psychiatry, Geriatric Psychiatry, Atypical Dementia, Creutzfeldt-Jakob Disease and Frontotemporal Dementia

Sees Patients at: UH Foley ElderHealth Center

Christopher Bailey, PhDOffice Phone: 216-844-3422Appointment Phone: 216-844-2724

Special Interests: Adult/Geriatric Neuropsychology, Alzheimer’s Disease, Attention-Deficit/Hyperactivity Disorder (ADD/ADHD), Concussion, Dementia, Disability/Legal, Deep Brain Stimulation Surgery, Epilepsy and Epilepsy Surgery, Forensic Neuropsychology, Hydrocephalus, Memory Loss, Mild Cognitive Impairment, Neuropsychological Independent Medical Exam, Traumatic Brain Injury (TBI)

Sees Patients at: UH Case Medical Center, UH Ahuja Medical Center

Suzanne Debrosse, MDOffice Phone: 216-844-3936Appointment Phone: 1-866-UH4-CARE

Special Interests: Pediatric Genetics, Genetics

Sees Patients at: UH Case Medical Center

Philip Fastenau, PhDOffice Phone: 216-844-3422Appointment Phone: 216-844-2724

Special Interests: Alzheimer’s Disease, Attention-Deficit/Hyperactivity Disorder (ADD/ADHD), Concussion, Deep Brain Stimulation Surgery, Dementia, Epilepsy and Epilepsy Surgery, Hydrocephalus, Learning Disability (LD), Memory Loss, Mild Cognitive Impairment, Neuropsychological Test Development, Pediatric/Adult/Geriatric Neuropsychology, Traumatic Brain Injury (TBI)

Sees Patients at: UH Case Medical Center,UH Westlake Health Center

Cynthia Griggins, PhDOffice Phone: 216-844-1852Appointment Phone: 216-844-2724

Special Interests: ADHD and Learning Disabilities in Adults, Chronic Medical Conditions, Clinical Ethics, Cognitive Rehabilitation, Counseling and Therapy for Neurological Disorders, Dementia, Head Injury, Higher Cortical Functions, Language Mapping, Neuroethics, Neuropsychological Assessment of Adults and Adolescents, Stroke

Sees Patients at: UH Case Medical Center

Steven A. Gunzler, MDOffice Phone: 216-844-8685Appointment Phone: 216-844-2724

Special Interests: Ataxia, Neurology, Dystonia, Memory and Aging, Botulinum Toxin Injections, Movement Disorders, Dementia, Parkinson’s Disease, Huntington’s Disease, Tremors

Sees Patients at: UH Ahuja Medical Center, UH University Suburban Health Center, UH Foley ElderHealth Center

James Mack, PhDOffice Phone: 216-844-3188

Special Interest: Neuropsychiatry

Sees Patients at: UH Rehabilitation Hospital

Paula K. Ogrocki, PhDOffice Phone: 216-464-6412Appointment Phone: 216-464-6445

Special Interests: Alzheimer’s Disease & Dementia, Geriatric Neuro-Psychology, Memory and Aging, Licensed Clinical Psychologist, Forgetfulness, Psychological Testing

Sees Patients at: UH Ahuja Medical Center

BRAIN HEALTH & MEMORY CENTER

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UH Neurological Institute’s Brain Tumor & Neuro-Oncology

Center facilitates seamless collaborations between

University Hospitals world-renowned main campus facilities,

UH Seidman Cancer Center and UH Rainbow Babies &

Children’s Hospital to treat adult and pediatric patients

with both benign and malignant tumors. The interdisciplinary

approach enables UH Case Medical Center to offer a

personalized treatment plan for each patient and their

referring physician, while simultaneously giving them access

to top experts in the field and the most advanced clinical

trials available.

Surgical solutions:• Laser Interstitial Thermotherapy (NeuroBlate® System) in the

intraoperative MRI

• Gamma Knife® and CyberKnife® Radiosurgery for brain and spine tumors

• Image-guided surgical navigation

• Intraoperative magnetic resonance imaging operating room

• Intraoperative brain mapping of tumor and functionally critical brain involving motor, language, sensory, visual and cranial nerves

• Endoscopic neurosurgical techniques

• Multidisciplinary skull-base approaches

Minimally invasive and nonsurgical solutions:• Laser Interstitial Thermotherapy (NeuroBlate® System) in the

intraoperative MRI

• Gamma Knife® Radiosurgery

• CyberKnife® Radiosurgery

Conditions treatedThe Brain Tumor & Neuro-Oncology Center treats adult and pediatric patients with both benign and malignant tumors, including:

• Acoustic neuromas

• Astrocytomas

• Brain stem gliomas

• Ependymomas

• Glioblastomas

• Gliomas

• Medulloblastomas

• Meningiomas

• Mixed gliomas

• Neurofibromatosis 1 & 2

• Oligoastrocytomas

• Oligodendrogliomas

• Optic nerve gliomas

• Pilocytic Astrocytomas

• Skull-base tumors

Laser Interstitial Thermotherapy in the intraoperative MRI

UH Case Medical Center was one of two hospitals to help Monteris Medical, Inc. pioneer the NeuroBlate® System. This new technology enables the surgeon to use MRI-guided lasers to destroy previously

inoperable tumors without damaging the surrounding healthy tissue. This revolutionary technology and minimally invasive

approach is especially effective in treating glioblastoma, one of the most aggressive and difficult-to-treat brain cancers. UH Case

Medical Center is one of only nine hospital centers in the United States using this technology.

BRAIN TUMOR & NEURO-ONCOLOGY CENTER

InnovationsSurgeons at UH are pioneering new approaches of minimally invasive brain surgery including:

• Laser Interstitial Thermotherapy with real-time MRI using the Monteris NeuroBlate® System

• Brain mapping with functional MRI (fMRI), Diffusion Tensor Imaging (DTI) and/or magnetoencephalography (MEG) to optimize identification of brain tumors and surrounding normal tissues

• Intraoperative MRI to maximize safety and completeness of tumor removal

• New techniques for optical and fluorescence imaging to better identify infiltrating tumor

• Convection Enhanced Delivery (CED): A technology to improve delivery of small anti-tumor molecules and chemotherapy to brain tumors

• Stereotactic Radiosurgery using Gamma Knife® or CyberKnife®

Current clinical trials:• 06-benzylguanine (BG) and Temozolomide (TMZ) Therapy

of Glioblastoma Multiforme (GBM) in Patients with MGMT Positive Tumors with Infusion of Autologous P140KMGMT+ Hematopoietic Progenitors to Protect Hematopoiesis

• Fluorescence-Guided Detection of Malignant Gliomas: A Dose Ranging Study Using 5-Aminolevulinic Acid (ALA) Induced Protoporphyrin (PpIX) in a Multicenter Phase II Clinical Trial

• A Phase II Clinical Trial Evaluating DCVax-Brain, Autologous Dendritic Cells Pulsed with Tumor Lysate Antigen for the Treatment of Glioblastoma Multiforme

• A Phase I Study of Methoxyamine and Temozolomide in Patients with Advanced Solid Tumors

• Phase III Study of Radiation Therapy with or without Temozolomide for Symptomatic or Progressive Low-Grade Gliomas

• Phase II Trial of Observation for Low-Risk Meningiomas and of Radiotherapy for Intermediate and High-Risk Meningiomas

Nontherapeutic:• International Case-Control Study of Malignant Glioma

(A GLIOGENE Consortium Site)

• The Cancer Genome Atlas Patient Enrollment and Specimen Qualification Criteria Glioblastoma Multiforme

• Biorepository and Tissue Processing Core Facility

• Ohio Brain Tumor Study

• GLIOGENE: An International Brain Tumor Linkage Consortium Site

All National Institutes of Health funding for basic and clinical research is awarded to the School of Medicine at Case Western Reserve University.

Daily interactions among multidisciplinary team members, combined with the most current treatment protocols, facilitate rapid response to individual therapeutic needs and modifications as necessary.

ProgramsSpecialized programs allow physicians to develop appropriate paths to create personalized treatment plans with specialists from other areas of excellence within UH. Programs include:

• Benign Brain Tumor Program: Incorporates minimally invasive and image-guided approaches, endoscopic, skull base and radiosurgical techniques to treat and often cure benign tumors of the brain.

• Malignant Brain Tumor Program: Offers patients and referring physicians a personalized approach to innovative new therapies including new surgical techniques and technology and advanced therapeutic agents. Surgical trials include minimally invasive laser interstitial therapy with real-time intraoperative MRI, new methods of imaging to improve resection including optical imaging of tumor and intraoperative MRI guided resection.

BRAIN TUMOR & NEURO-ONCOLOGY CENTER

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Other novel therapies include tumor vaccines (immunotherapy), targeting tumor stem cells, use of normal hematopoetic stem cells to minimize chemotherapy induced complications, and advanced chemotherapy in combination with anti-angiogenic approaches through internal trials at UH Case Medical Center, the Case Comprehensive Cancer Center, the Adult Brain Tumor Consortium (ABTC) and the Radiation Therapy and Oncology Group (RTOG).

• Metastatic Brain Tumor Program: Treatment approaches include integration of radiotherapy and radiosurgical approaches with Gamma Knife® and CyberKnife®, as well as advanced surgical techniques, to optimize outcomes and minimize risk.

• Skull Base Surgery Program: A multidisciplinary team of neurosurgeons, head and neck surgeons, otolaryngologists, ophthalmologists and radiation oncologists who use minimally invasive, image-guided and radiosurgical techniques to optimize outcome and minimize risk.

• Pediatric Neuro-oncology: Provides comprehensive, coordinated care through research, clinical care and support services to pediatric patients with brain and spinal tumors and their families. Using an integrated team approach, the center leverages the expertise of its nationally recognized specialists in neurosurgery, neurology, neuro-oncology, oncology, radiation oncology, neuro-pathology, otolaryngology and radiology. The team’s focus on innovation and research ensures that our pediatric patients are among the first to receive groundbreaking treatments and therapies.

• Pituitary/Neuro-Endocrine Program: Multidisciplinary team of neurosurgeons, skull base surgeons, radiation oncologists and endocrinologists employ a team approach to diagnose and treat disease of the pituitary and neuro-endocrine system.

• Spine Tumor Program: Integrated team of radiation oncologists, spinal surgical oncologists, medical oncologists, orthopaedic specialists and rehabilitation specialists focused on diagnosis and treatment of spinal neoplasms.

• Neurofibromatosis 2 Center: The UH Neurofibromatosis 2 Center is comprised of a multidisciplinary group of surgeons and specialists in neurosurgery, neurology, oncology, otolaryngology and genetics. Our team also includes specialists and subspecialists in all related areas, including radiology, ophthalmology and radiation therapy, as well as various supporting services. We offer standard and innovative treatment options including management through medication, radiation or surgery. Hearing rehabilitation using auditory brainstem implants (ABI) or cochlear implantation (when appropriate) also are available. Because NF2 can impact hearing, patients and families may have difficulty coping with this disorder. To help increase their understanding and make them more comfortable, we provide information about treatment options, keep them updated on the patient’s progress and encourage them to ask questions. The goal is to help patients heal both medically and emotionally, and enhance their overall quality of life.

• Treatment of Brain Tumors in the Elderly: Integrated and multidisciplinary approach to tailoring treatments from other programs to accommodate patients over the age of 65.

• Neuro-Oncology Cancer Pain Program: Integrated multidisciplinary approach to treatment of cancer-related pain for patients with brain tumors.

• Stereotactic Radiosurgery: Multidisciplinary team of neurosurgeons, spine surgeons, radiation oncologists, physicists and medical oncologists utilizing state-of-the-art technology Gamma Knife® Perfexion® and CyberKnife® for minimally invasive approaches to the treatment of lesions of the brain and spine.

• Pediatric Neurosurgery: Our expert neurosurgeons are skilled in the latest approaches and use the latest technologies to provide customized surgical solutions to pediatric patients with a wide variety of neurological conditions.

Simon Lo, MD, Radiation Oncologist and Director for Radiosurgery, has helped formulate a new method for precisely determining the dosage used for patients receiving a limited number (one to five) of Gamma Knife® or CyberKnife® treatments. This independently validated approach is safer when used alone or in conjunction with chemotherapy as it minimizes the damage to surrounding tissue and results in more favorable outcomes for our patients.

Specialized equipment:• Laser Interstitial Thermotherapy (LITT) in the intraoperative MRI

• Gamma Knife®

• CyberKnife®

• Intraoperative MRI (iMRI)

CyberKnife®

BRAIN TUMOR & NEURO-ONCOLOGY CENTER

Andrew E. Sloan, MDOffice Phone: 216-844-6054Appointment Phone: 216-844-2724

Special Interests: Convection Enhanced Delivery (CED), Tumor Vaccines (Immunotherapy), Brain Tumors, Skull Base Surgery, Gamma Knife® and CyberKnife® Stereotactic Radiosurgery, Image Guided Neurosurgery, Stereotactic Surgery, Neuro-oncology, Spinal Cord Tumors

Sees Patients at: UH Case Medical Center

Baha Arafah, MDOffice Phone: 216-844-3142Appointment Phone: 216-844-8500

Special Interests: Endocrinology, Pituitary Disorders, Adrenal Disorders

Sees Patients at: UH Case Medical Center

Nicholas C. Bambakidis, MDOffice Phone: 216-844-8758Appointment Phone: 216-844-2724

Special Interests: Neuro-oncology, Spinal Cord Tumors, Skull Base Surgery

Sees Patients at: UH Case Medical Center, UH Ahuja Medical Center

David Bardenstein, MDOffice Phone: 216-844-8686Appointment Phone: 216-844-1700

Special Interests: Ophthalmology, Orbital Disease, Ocular Oncology, Ocular Pathology, Ophthalmic Reconstructive Surgery, Cancer of the Eye, Eye Disease, Eye Pathology, Eye Reconstructive Surgery, Melanoma

Sees Patients at: UH Case Medical Center, UH Landerbrook Health Center, UH Westlake Health Center

Michael Coffey, MDOffice Phone: 216-844-3061Appointment Phone: 216-844-2724

Special Interests: MRI, Neuroradiology

Sees Patients at: UH Case Medical Center

Mark L. Cohen, MDOffice Phone: 216-844-8928

Special Interest: Diagnostic Neuropathology

Sees Patients at: UH Case Medical Center

Peter de Blank, MD, MSOffice Phone: 216-844-3345Appointment Phone: 1-866-UH4-CARE

Special Interests: Pediatric Hematology/Oncology, Pediatrics

Sees Patients at: UH Rainbow Babies & Children’s Hospital

Stanton Gerson, MDOffice Phone: 216-844-8562Appointment Phone: 1-866-UH4-CARE

Special Interests: Hematology, Leukemia, Lymphoma, Malignant Hematology, Myelodysplasia, Myeloma, Oncology, Transplantation

Sees Patients at: UH Case Medical Center, UH Chagrin Highlands Health Center

Joseph Gibbons, MDOffice Phone: 216-844-4735Appointment Phone: 1-866-UH4-CARE

Special Interests: Bone & Soft Tissue Cancer, Breast Cancer, Gastrointestinal Cancer, Genitourinary Cancer, Hematology/Oncology, Sarcoma

Sees Patients at: UH Case Medical Center, UH Chagrin Highlands Health Center, UH Westlake Health Center

Deborah Gold, MDOffice Phone: 216-844-3691Appointment Phone: 216-844-7700

Special Interests: Pediatric Neurology, Neuro-oncology, Pediatric Stroke

Sees Patients at: UH Rainbow Babies & Children’s Hospital, UH Rainbow Specialty Center – Landerbrook, UH Mentor Health Center

Seth Alan Hoffer, MDOffice Phone: 216-844-5744Appointment Phone: 216-844-2724

Special Interest: Spinal Cord Tumors

Sees Patients at: UH Case Medical Center, UH Bedford Medical Center, UH Richmond Medical Center

BRAIN TUMOR & NEURO-ONCOLOGY CENTER

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UHhospitals.org/Neuro • UH Neurological Institute | 1514 | University Hospitals • 216-844-2724

Henry B. Koon, MDOffice Phone: 216-844-0120Appointment Phone: 216-844-7700

Special Interests: Hematology/Oncology, Melanoma, Cutaneous Lymphoma, Renal Cell Carcinoma, Immunotherapy, Bone & Soft Tissue Cancer

Sees Patients at: UH Case Medical Center, UH Chagrin Highlands Health Center, UH Westlake Health Center

Charles Lanzieri, MDOffice Phone: 216-844-5721

Special Interests: CNS Imaging, Head and Neck Imaging, Interventional Neuroradiology

Sees Patients at: UH Case Medical Center

Simon Lo, MDOffice Phone: 216-844-3103Appointment Phone: 216-844-2724

Special Interests: Gamma Knife® Radiosurgery, Brain & Spinal Tumors, Stereotactic Body Radiation Therapy, Stereotactic Ablative Radiotherapy, Bone Metastasis

Sees Patients at: UH Case Medical Center

Joseph A. Locala, MDOffice Phone: 216-844-2400Appointment Phone: 216-844-2400

Special Interests: Adult Psychiatry, Psychosomatic Psychiatry, Psychiatric Care of Medically Ill Patients, Transplant Psychiatry, Mood Disorders in the Medically Ill, Anxiety Disorders in the Medically Ill

Sees Patients at: UH Case Medical Center, UH Seidman Cancer Center, W.O. Walker Center

Janice A. Lyons, MDOffice Phone: 216-844-2536Appointment Phone: 216-844-3951

Special Interests: Radiation Oncology, Breast Cancer

Sees Patients at: UH Case Medical Center, UH Chagrin Highlands Health Center, UH Westlake Health Center

Mitchell Machtay, MDOffice Phone: 216-844-2530Appointment Phone: 216-844-3951

Special Interests: Lung Cancer, Head and Neck Cancer, Brain/Spine Tumors, IMRT and Radiosurgery, Bone & Soft Tissue Cancer, Neuro-oncology, Genitourinary Oncology, Gynecologic Cancer, Malignant Hematology, Pediatric Hematology/Oncology

Sees Patients at: UH Case Medical Center

Cliff A. Megerian, MDOffice Phone: 216-844-5500Appointment Phone: 216-844-6000

Special Interests: Hearing Loss, Otitis, Chronic Ear Disease, Surgery for Hearing Loss and Tumor, Vertigo, Meniere’s Disease, Dizziness, Neurotology, Skull Based Surgery, Acoustic Neuromas

Sees Patients at: UH Case Medical Center, UH Chagrin Highlands Health Center, UH Westlake Health Center

Jonathan Miller, MDOffice Phone: 216-844-3470Appointment Phone: 216-844-2724

Special Interests: Cancer Pain, Stereotatic & Functional Neurosurgery, Gamma Knife® Stereotactic Radiosurgery, Neuro-oncology, Spinal Cord Tumors

Sees Patients at: UH Case Medical Center

Charles Nock, MDOffice Phone: 216-844-3682Appointment Phone: 216-844-3951

Special Interests: Melanoma, Genitourinary Malignancies, Neuro-oncology

Sees Patients at: UH Case Medical Center, UH Westlake Health Center

Susan Padrino, MDOffice Phone: 216-844-3400Appointment Phone: 216-844-3400

Special Interests: Adult Psychiatry, Community Psychiatry, Internal Medicine, Resident Education, Medical Student Education, Physical Diagnosis, Direct Observation, Family Therapy, Residency Education

Sees Patients at: UH Case Medical Center, UH Seidman Cancer Center

BRAIN TUMOR & NEURO-ONCOLOGY CENTER

Stefani Parrisbalogun, MDOffice Phone: 216-983-5650Appointment Phone: 216-983-5650

Special Interests: Adult Psychiatry, Psychiatric Care of Medically Ill Patients, Psychosomatic Medicine, Emergency Psychiatry, HIV/AIDS Psychiatry, Bariatric Psychiatry

Sees Patients at: W.O. Walker Center, UH Seidman Cancer Center

Mark Rodgers, MDOffice Phone: 216-844-3478Appointment Phone: 216-844-2724

Special Interest: Anatomic Pathology

Sees Patients at: UH Case Medical Center

Lisa Rogers, DOOffice Phone: 216-844-3717Appointment Phone: 216-844-2724

Special Interests: Neuro-oncology, Brain Tumor, Neurological Complications of Cancer

Sees Patients at: UH Case Medical Center, UH Ahuja Medical Center, UH Chagrin Highlands Health Center

Warren R. Selman, MDOffice Phone: 216-844-5745Appointment Phone: 216-844-2724

Special Interests: Skull Base Tumors, Acoustic Neuromas, Meningiomas, Pituitary Tumors, Spinal Cord Tumors

Sees Patients at: UH Case Medical Center

Binit Shah, MDOffice Phone: 216-844-3771Appointment Phone: 216-844-3771

Special Interests: Psycho-Oncology, Chronic Pain, Pain Rehabilitation

Sees Patients at: UH Case Medical Center, UH Seidman Cancer Center, W.O. Walker Center

Paula Silverman, MDOffice Phone: 216-844-8510Appointment Phone: 216-844-3951

Special Interests: Hematology and Oncology, Breast Cancer

Sees Patients at: UH Case Medical Center, UH Chagrin Highlands Health Center, UH Westlake Health Center

Duncan Stearns, MDOffice Phone: 216-286-7400Appointment Phone: 1-866-UH4-CARE

Special Interests: Pediatric Hematology/Oncology, Pediatrics

Sees Patients at: UH Rainbow Babies & Children’s Hospital

Jeffrey L. Sunshine, MD, PhDOffice Phone: 216-844-3112Appointment Phone: 216-844-3112

Special Interests: Neuroradiology, Interventional Neuroradiology, Head and Neck Imaging, MRI, Acute Stroke Treatment, Brain Aneurysm, Carotid Stenosis, Brain and Spine AVM, Intracranial Stenosis, MR Imaging Head, Neck, Spine

Sees Patients at: UH Case Medical Center

Krystal Tomei, MD, MPHOffice Phone: 216-844-5741Appointment Phone: 216-844-7337

Special Interests: Hydrocephalus, Pediatric Brain Tumors, Congenital Spinal Disorders and Spina Bifida, Tethered Cords, Craniosynostosis, Spasticity, Spinal Deformities, Pediatric Traumatic Brain Injury, Pediatric Spinal Injury

Sees Patients at: UH Rainbow Babies & Children’s Hospital

BRAIN TUMOR & NEURO-ONCOLOGY CENTER

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UHhospitals.org/Neuro • UH Neurological Institute | 1716 | University Hospitals • 216-844-2724

At the Community Neurology Center, our experienced

doctors use an interdisciplinary, highly integrated approach

to care for patients with undiagnosed neurological disorders

or those seeking second opinions. Offering appointment

accessibility in many locations throughout the greater

Cleveland area, patients receive a comprehensive

evaluation, treatment, prevention and rehabilitation

services. The programs are led by clinicians who are

recognized and respected for accomplishments in their

respective fields of expertise.

Patients who visit our community facilities receive the same level of clinical expertise and comprehensive range of neurological services available at UH Case Medical Center. The neurologists and neurosurgeons at these locations are supported by the UH Neurological Institute and have unfettered access to its multidisciplinary team of specialists, leading-edge technology and complete range of medical resources.

Conditions treatedThe Community Neurology Center provides comprehensive care for patients with diseases of the nervous system. Conditions treated include:

• Advanced back and spine surgery

• Alzheimer’s and dementia disorders

• Autonomic disorders

• Brain surgery

• Chronic pain

• Epilepsy

• Fibromyalgia

• General neurology conditions and disorders

• Headache (including migraine)

• Multiple sclerosis

• Neuromuscular diseases

• Parkinson’s disease

• Peripheral neuropathy

• Radiculopathy

• Stroke

• And more

Programs:• Headache Management: Diagnose and treat migraine, cluster,

sinus and tension headaches.

• Neuro-ophthalmology: Diagnose and manage treatment for patients experiencing visual disturbances from optic nerve diseases, central nervous system disorders, ocular motility dysfunction and pupillary abnormalities. Patients benefit from collaboration between clinicians and world-renowned investigators in the field of eye movements.

• Multiple Sclerosis: Experienced experts provide early diagnosis and treatment with the latest disease-modifying drugs to positively alter the course of multiple sclerosis.

• Pain Management: Management of neuropathic pain syndromes such as radiculopathies, trigeminal neuralgia, postherpetic neuralgia, phantom limb pain, complex regional pain syndromes and the various peripheral neuropathies.

• Sleep Disorders: Diagnose and manage a variety of sleep disorders including sleep apnea, narcolepsy, restless leg syndrome, insomnia, circadian rhythm disorders and parasomnia.

Specialized equipment:• EEG are recorded in community locations and read by world

renowned epileptologists at UH Case Medical Center.

• EMG tests are performed by registered technologists and physicians with subspecialty training in neuromuscular and electrodiagnostic medicine.

• Autonomic Lab full tests are performed throughout community locations.

COMMUNITY NEUROLOGY CENTER

John Andrefsky, MDOffice Phone: 440-743-8120Appointment Phone: 216-844-2724

Special Interests: General Neurology, Stroke

See Patients at: UH Parma Medical Center

Marek A. Buczek, MDOffice Phone: 440-250-5303Appointment Phone: 216-844-2724

Special Interests: General Neurology, Electrophysiology, Headache, Chronic Pain Syndromes, Head Injury, Language Mapping

Sees Patients at: UH Case Medical Center, UH Westlake Health Center, St. John Medical Center

Michael W. Devereaux, MDOffice Phone: 216-844-3591Appointment Phone: 216-844-2724

Special Interests: Multiple Sclerosis, Epilepsy, General Neurology, Neuro-Ophthalmology

Sees Patients at: UH Case Medical Center, UH Ahuja Medical Center, UH Richmond Medical Center, UH University Suburban Health Center, UH Geneva Medical Center, UH Medina Health Center

Stefan Dupont, MD, PhDOffice Phone: 216-285-5041Appointment Phone: 216-844-2724

Special Interests: Neurology, Vascular Neurology, Stroke

Sees Patients at: UH Ahuja Medical Center

COMMUNITY NEUROLOGY CENTER

Suresh Kumar, MDOffice Phone: 440-816-6794Appointment Phone: 440-816-6794

Special Interest: Neurology

Sees Patients at: UH Parma Medical Center, Southwest General Health Center

Daniel W. Miller, MDOffice Phone: 216-844-7380Appointment Phone: 216-844-2724

Special Interests: General Neurology, Neuromuscular Disorders, Neurophysiology, EMG

Sees Patients at: UH Case Medical Center, UH University Suburban Health Center

Kempsagar Ravishankar, MDOffice Phone: 440-826-9221Appointment Phone: 440-826-9221

Special Interest: Neurology

Sees Patients at: Southwest General Health Center

Mark Rorick, MDOffice Phone: 440-285-2888Appointment Phone: 216-844-2724

Special Interest: General Neurology

Sees Patients at: UH Geauga Medical Center, UH Mentor Health Center

Alessandro Serra, MD, PhDOffice Phone: 216-844-3193Appointment Phone: 216-844-2724

Special Interests: Multiple Sclerosis, Neuroimmunological Disorders

Sees Patients at: UH Case Medical Center, UH Ahuja Medical Center

Tanvir U. Syed, MDOffice Phone: 440-827-5061Appointment Phone: 216-844-2724

Special Interests: Intraoperative Monitoring, Epilepsy, Language Mapping, Higher Cortical Functions, Pseudoseizures, Outcomes Research, Biostatistics, Psychogenic Nonepileptic Seizures

Sees Patients at: UH Westlake Health Center, St. John Medical Center, UH Medina Health Center

Marie Tani, MDOffice Phone: 440-357-3100Appointment Phone: 440-357-3100

Special Interests: General Neurology, Multiple Sclerosis

Sees Patients at: UH Concord Health Center

Colleen B. Tomcik, MDOffice Phone: 440-735-4723Appointment Phone: 216-844-2724

Special Interests: Higher Cortical Functions, Medical Education, Neurology, Headache

Sees Patients at: UH Case Medical Center, UH Ahuja Medical Center, UH Bedford Medical Center, UH Twinsburg Health Center

Mark Walker, MDOffice Phone: 216-286-0315Appointment Phone: 216-286-0315

Special Interests: Vestibular Disorders, Vertigo, Eye Movement Disorders, Nystagmus, Cerebellar Ataxia

Sees Patients at: UH Case Medical Center

Leonard Weinberger, MDOffice Phone: 440-357-3100Appointment Phone: 440-357-3100

Special Interests: General Neurology, Parkinson’s Disease, EMG

Sees Patients at: UH Concord Health Center

Norton A. Winer, MDOffice Phone: 216-383-7850Appointment Phone: 216-383-7850

Special Interests: Sports Related Neurological Injuries, Cerebrovascular Disease, Carotid Ultrasonography, Pain Management

Sees Patients at: UH Richmond Medical Center, UH Mentor Health Center

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UHhospitals.org/Neuro • UH Neurological Institute | 1918 | University Hospitals • 216-844-2724

UH Neurological Institute’s Comprehensive Stroke Center

is the premier leader in stroke care in Northeast Ohio.

UH Case Medical Center was the first hospital in

Northeast Ohio to achieve The Joint Commission’s

standards for Comprehensive Stroke Center Certification.

The center also has the most experienced stroke team in Northeast Ohio with a world-class, multidisciplinary team including five board-certified vascular neurologists, four neurointensivists, three interventional neuroradiologists and two cerebrovascular neurosurgeons.

The Joint Commission also has designated UH Ahuja Medical Center, UH Bedford Medical Center, UH Geauga Medical Center, UH Parma Medical Center, UH Richmond Medical Center, St. John Medical Center and Southwest General Health Center as certified Primary Stroke Centers. UH Case Medical Center also meets Brain Attack Coalition criteria for a comprehensive stroke center and has a dedicated stroke inpatient service.

Minimally invasive and nonsurgical solutions:• Treatment of complex vascular malformations deemed

“inoperable” with “knifeless” procedures such as Gamma Knife® and CyberKnife® Stereotactic Radiosurgery

• Experienced team of neuro-interventionalists offering minimally invasive endovascular ablation of aneurysms and AVMs, angioplasty and stenting of extracranial and intracranial stenosis, and emergency treatment of acute stroke or vasospasm

Surgical solutions:• Aneurysm repair, vascular reformations and

diseased-artery bypasses

• Carotid revascularization and EC-IC bypass procedures

Conditions treated:• Diagnosis and management of complex diseases in patients

with vascular disorders of the brain or spine including those considered high-risk due to age, co-morbid conditions or inability to tolerate anesthesia

• Emergent evaluation of transient ischemic attacks and stroke

• Aneurysms

• Arteriovenous malformations (AVMs), dural and cavernous malformations

• Intracranial stenosis

• Carotid artery atherosclerotic stenosis or occlusion

• Stroke due to cardiac disease, including patent foramen ovale (PFO)

• Lacunar or small vessel disease

• Carotid or vertebral artery dissection

• Cerebral vasculitis

• Other unusual causes – mitochondrial disorders, CADASIL, migraine

InnovationsThe Comprehensive Stroke Center’s connection with Case Western Reserve University School of Medicine enables basic science research to be translated to findings that will improve future patient care. Recent major activities include:

• Joseph LaManna, PhD, Director of the BrainLab, has been involved in cerebral blood flow and metabolism research for over 30 years. Dr. LaManna is investigating energy demand, energy metabolism and blood flow in the brain, as well as the roles of mechanisms associated with tissue response to pathological insults such as stroke (cerebral edema), hypoxia and seizures.

• Sophia Sundararajan, MD, PhD, is leading an NIH-funded, K08-award investigating the role of PPAR agonists to limit inflammation and damage caused by a stroke.

• Janis J. Daly, PhD, MS, Director, Cognitive and Motor Learning Research Program, EUREKA study to treat the brain (where the stroke occurred), using electroencephalography (EEG) signals to direct brain retraining following stroke to measure the potential to more completely restore normal brain and motor function to a greater number of patients in shorter rehabilitation time.

COMPREHENSIVE STROKE CENTER

Current clinical trialsThe Comprehensive Stroke Center participates in groundbreaking clinical research trials to provide patients with access to therapies that are not otherwise available or reimbursed by their insurance.

• Surgical Rehearsal Platform (SRP). Surgical Rehearsal Platform is software that provides virtual imagery for high-risk, open/classic surgery; and cerebral aneurysm clipping. This technology enables the surgeon to gain currently unobtainable presurgery insights needed to refine the performance of time-critical tasks on a patient-specific basis. The main objective of this clinical study is to determine if the use of the SRP will lead to improved effort and time efficiency in cerebral aneurysm surgery. We will be looking at the number of clipping attempts and adjustments, time of temporary occlusion, number of clips wasted and other surgical data.

• CLEAR. The purpose of this Phase III randomized clinical trial (RCT) is to compare a policy of early extraventricular drain (EVD) use and recombinant tissue plasminogen activator (rt-PA, Cathflo® Activase® Genentech, Inc., San Francisco, CA) with EVD use and placebo (normal saline) the treatment of subjects with intracerebral hemorrhage (ICH) and intraventricular hemorrhage (IVH) with obstruction of the third or fourth ventricles by blood. We will evaluate a population of 500 ICH subjects with intraventricular hemorrhage, representative of current clinical practice and national demographics of ICH.

• Athersys. The primary objectives of this trial are the following:

- To determine the highest well-tolerated and safest single dose of MultiStem up to a maximum of 1200 million total cells in subjects with ischemic stroke and

- To determine the efficacy of MultiStem on functional outcome in subjects with ischemic stroke.

The secondary objectives of this trial are the following:

- To determine the safety of MultiStem in subjects with ischemic stroke and

- To determine changes in functional outcomes and disease severity outcomes of ischemic stroke in subjects treated with MultiStem.

The exploratory objectives of this trial are to evaluate changes in brain and spleen imaging metrics and blood biomarker outcomes as well as the incidence of infection (local and systemic) in ischemic stroke subjects treated with MultiStem.

• ATACH-II. To determine the therapeutic benefit of intensive SBP treatment (SBP<140 mmHg) compared with standard SBP treatment (SBP<180 mmHg) in reducing the proportion of patients with death and disability (mRS of 4-6) at Day 90 among subjects with ICH treated within 3.5 hours of symptom onset.

• StrokeNet. The StrokeNet grant is a new way of operating and conducting collaborative clinical NIH trials across the country. Cleveland has been chosen as a Regional Coordinating Center which is comprised of the four major health care institutions (CCF, Metro, UH, VA) along with its satellite hospital systems to conduct NIH stroke and neurology research. What makes this unique is that all four institutions and its corresponding satellite hospitals will operate and conduct clinical research trials under one financial budget and contract and utilize one central IRB. This will allow for us to maximize efficiencies in the development, promotion and conduct of multisite exploratory Phase I, II and confirmatory Phase III clinical trials in stroke prevention, treatment and recovery that are funded by NIH.

ProgramsDedicated Stroke Prevention Clinic:

• Initial evaluation, ongoing therapy with rehabilitation specialists who employ state-of-the-art techniques to speed recovery after stroke and management of co-morbid conditions.

• Neuroscience Intensive Care Unit staffed by neurointensivists and specialty-trained nurses providing round-the-clock care for critically ill patients.

Pediatric Neurosurgery:

Our expert neurosurgeons are skilled in the latest approaches and use the latest technologies to provide customized surgical solutions to pediatric patients with a wide variety of neurological conditions.

Special equipment:• Extensive array of diagnostic modalities including MR diffusion/

perfusion, MRA, MRV, CTA, CT perfusion, SPECT, PET, carotid duplex and Transcranial Doppler

To access the stroke team at UH Case Medical Center 24/7 for patient transfers or urgent advice, call the transfer line at 216-844-1111.

For patients or physicians requesting outpatient consults, second opinions or stroke prevention trials call 216-844-2724.

UH Case Medical Center was the first certified Comprehensive Stroke Center in Northeast Ohio.

This certification showcases our ability to treat the most complex cases and deliver the highest quality stroke care in the region.

COMPREHENSIVE STROKE CENTER

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UHhospitals.org/Neuro • UH Neurological Institute | 2120 | University Hospitals • 216-844-2724

Sophia Sundararajan, MDOffice Phone: 216-844-8421Appointment Phone: 216-844-2724

Special Interests: Cerebrovascular Disorders, Acute Intervention, Stroke Recovery, Stroke, Acute Stroke Treatment, TIA

Sees Patients at: UH Case Medical Center,UH Mentor Health Center

Jeffrey L. Sunshine, MD, PhDOffice Phone: 216-844-3112Appointment Phone: 216-844-3112

Special Interests: Neuroradiology, Interventional Neuroradiology, Head and Neck Imaging, MRI, Acute Stroke Treatment, Brain Aneurysm, Carotid Stenosis, Brain and Spine AVM, Intracranial Stenosis, MR Imaging Head, Neck, Spine

Sees Patients at: UH Case Medical Center

Tanvir U. Syed, MDOffice Phone: 440-827-5061Appointment Phone: 216-844-2724

Special Interests: Intraoperative Monitoring, Epilepsy, Language Mapping, Higher Cortical Functions, Pseudoseizures, Outcomes Research, Biostatistics, Psychogenic Nonepileptic Seizures

Sees Patients at: UH Westlake Health Center, St. John Medical Center, UH Medina Health Center

Robert W. Tarr, MDOffice Phone: 216-844-5722

Special Interests: Neuroradiology, Interventional Neuroradiology

Sees Patients at: UH Case Medical Center

Colleen B. Tomcik, MDOffice Phone: 440-735-4723Appointment Phone: 216-844-2724

Special Interests: Higher Cortical Functions, Medical Education, Neurology, Headache

Sees Patients at: UH Case Medical Center, UH Bedford Medical Center, UH Twinsburg Health Center,UH University Suburban Health Center

Mark Walker, MDOffice Phone: 216-286-0315Appointment Phone: 216-286-0315

Special Interests: Vestibular Disorders, Vertigo, Eye Movement Disorders, Nystagmus, Cerebellar Ataxia

Sees Patients at: UH Case Medical Center

Norton A. Winer, MDOffice Phone: 216-383-7850Appointment Phone: 216-383-7850

Special Interests: Stroke, Sports Related Neurological Injuries, Cerebrovascular Disease, Carotid Ultrasonography, Pain Management

Sees Patients at: UH Euclid Health Center,UH Mentor Health Center

Wei Xiong, MDOffice Phone: 216-844-0474Appointment Phone: 216-844-2724

Special Interests: Stroke, Hypothermia, Neurocritical Care, Cardiac Arrest

Sees Patients at: UH Geauga Medical Center

COMPREHENSIVE STROKE CENTER

Cathy A. Sila, MDOffice Phone: 216-844-8934Appointment Phone: 216-844-2724

Special Interests: Stroke in the Young, Stroke, TIA, Intracranial Stenosis, PFO, Cerebral Vasculitis, Carotid Stenosis, Dissection, Stroke Prevention

Sees Patients at: UH Case Medical Center, UH Ahuja Medical Center

Nicholas C. Bambakidis, MDOffice Phone: 216-844-8758Appointment Phone: 216-844-2724

Special Interests: Spinal Cord Injuries, Traumatic Brain Injury, Skull Base Surgery, Cerebrovascular Surgery

Sees Patients at: UH Case Medical Center, UH Ahuja Medical Center

Marek A. Buczek, MD, PhDOffice Phone: 440-250-5303Appointment Phone: 216-250-5303

Special Interests: General Neurology, Electrophysiology, Headache, Chronic Pain Syndromes, EMG, Head Injury

Sees Patients at: UH Case Medical Center, UH Westlake Health Center, St. John Medical Center

Michael DeGeorgia, MDOffice Phone: 216-844-1552Appointment Phone: 216-844-2724

Special Interests: Critical Care Bioinformatics, Hemorrhagic Stroke, Hypothermia, ICU Monitoring, Ischemic Stroke, Neurocritical Care

Sees Patients at: UH Case Medical Center

Stefan Dupont, MD, PhDOffice Phone: 216-285-5041Appointment Phone: 216-844-2724

Special Interests: Neurology, Vascular Neurology

Sees Patients at: UH Ahuja Medical Center

Ciro Estabenez, MDOffice Phone: 216-844-3192

Appointment Phone: 216-844-2724

Special Interests: General Neurology, Neuromuscular

Disorders, Neurocritical Care, Stroke

Sees Patients at: UH Case Medical Center

Anthony J. Furlan, MDOffice Phone: 216-844-3193Appointment Phone: 216-844-2724

Special Interests: PFO, Thrombolysis, Heart Disease and Stroke, Acute Stroke Treatment, Stroke, Cerebrovascular Disorders, Stroke Systems and Outcomes

Sees Patients at: UH Case Medical Center, UH Ahuja Medical Center

Daniel W. Miller, MDOffice Phone: 216-844-7380Appointment Phone: 216-844-3192

Special Interests: General Neurology, Neuromuscular Disorders, Neurophysiology, EMG

Sees Patients at: UH Case Medical Center, UH University Suburban Health Center

Mark Rorick, MDOffice Phone: 440-285-2888Appointment Phone: 216-844-2724

Special Interest: General Neurology

Sees Patients at: UH Geauga Medical Center, UH Mentor Health Center

Warren R. Selman, MDOffice Phone: 216-844-5745Appointment Phone: 216-844-2724

Special Interests: Cerebrovascular Surgery, Aneurysms, Arteriovenous Malformations and Occlusive Disorders

Sees Patients at: UH Case Medical Center

COMPREHENSIVE STROKE CENTER

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UHhospitals.org/Neuro • UH Neurological Institute | 2322 | University Hospitals • 216-844-2724

With level IV designations from the National Association of

Epilepsy Centers, the Epilepsy Center at UH Case Medical

Center and the Epilepsy Center at UH Rainbow Babies &

Children’s Hospital provide services to adult and pediatric

patients for consults or after previous treatments have failed.

Personalized treatment plans include clinical drug trials, novel

medications and advanced surgical therapies. Epileptologists

accurately classify, quantify and localize seizure-producing

areas of the patient’s brain by using the most advanced

diagnostic methods. The Epilepsy Center at UH Case Medical

Center and the Epilepsy Center at UH Rainbow Babies &

Children’s Hospital work together to deliver comprehensive

lifetime management of epilepsy and are national

destinations for both children and adults needing

surgery and complex treatment for epilepsy.

Surgical solutionsSeizures that do not respond to pharmaceutical management may be reduced or eliminated through epilepsy surgery. Advances in presurgical diagnostic techniques, including brain-mapping, expand therapeutic options to a larger percentage of epileptic patients.

• Temporal lobe resections

• Extratemporal lobe resections

• Lesionectomies

• Corpus callosum sections

• Selective amygdalo-hippocampectomies

• Multiple subpial transections

• Multiple hippocampal transections

• Hemispherectomies

• Vagal nerve stimulations

• Stereo-Electroencephalography (sEEG)

Minimally invasive and nonsurgical solutions:• Precise, noninvasive localization of epileptic foci by source-imaging

the electric or magnetic signal directly on the patient’s MRI

• Specialized MRI epilepsy-specific imaging protocols using 4 Tesla MRI, which can detect formerly hidden lesions

Conditions treatedThe epileptologists at UH specialize in all types of epilepsy, including:

• Adult epilepsy

• Developmentally delayed epilepsy

• Geriatric epilepsy

• Intractable epilepsy

• New onset epilepsy

• Pediatric epilepsy

• Women’s epilepsy

Innovations:• Cortical stimulation identifies brain areas involved with specific

cognitive functions like reading, writing and mathematical calculations, recognition of faces, etc.

• Cortico-cortical evoked potentials uncover brain to brain connections

• Advanced computer programs permit automatic recognition of the interictal and ictal epileptiform activity

• Multiple hippocampal transections reduce seizure activity while preserving memory functions

EPILEPSY CENTER

Current clinical trialsUH researchers are pioneering advances in the understanding of and causes of seizures through participation in various clinical and surgical studies including:

• The PRISM Project (1-P20-NS076965-01) is a National Institutes of Health (National Institute of Neurological Disorders and Stroke) funded multidisciplinary, multicenter collaboration between clinician researchers, basic scientists and expert engineers in bioinformatics and electrical engineering based at Case Western Reserve University. Its primary remit is to establish and facilitate research into Sudden Unexpected Death in Epilepsy (SUDEP), a significant, devastating public health problem that affects up to 5,000 individuals every year in the United States alone. In order to collect enough large-scale, multimodal physiological data for SUDEP patients, the project aims to establish a novel, online, web-based seizure data acquisition system capable of handling multimodal data, which will facilitate the bioinformatics core for sharing data with multiple epilepsy centers across the country.

• Targeted Self-Management for Epilepsy and Mental Illness: Epilepsy affects approximately 2 million Americans and is associated with substantial disability and a significantly increased risk of mortality and injury. Serious mental illnesses (SMI) such as psychotic conditions, bipolar disorder and chronic depression are common in people with epilepsy. This project targets the historically hard-to-reach group of individuals with epilepsy and with serious persistent mental illness (E-SMI), and will refine an intervention adapted for use in people with E-SMI, with the intent to improve both neurological and mental health outcomes.

• StrokeNet: The StrokeNet grant is a new way of operating and conducting collaborative clinical NIH trials across the country. Cleveland has been chosen as a Regional Coordinating Center which is comprised of the four major health care institutions (CCF, Metro, UH, VA) along with its satellite hospital systems to conduct NIH stroke and neurology research. What makes this unique is that all four institutions and its corresponding satellite hospitals will operate and conduct clinical research trials under one financial budget and contract and utilize one central IRB. This will allow for us to maximize efficiencies in the development, promotion and conduct of multisite exploratory Phase I, II and confirmatory Phase III clinical trials in stroke prevention, treatment and recovery that are funded by NIH.

Advances in presurgical diagnostic techniques, including brain-mapping, now offer surgical options to a significantly larger percentage of epileptic patients with medically intractable seizures.

Programs:• Epilepsy Monitoring Units (EMU): Provides separate units for

both adult and pediatric patients where anti-epileptic medications are reduced or removed and seizures are recorded with video/EEG to more precisely diagnose the type of epilepsy a patient has. Monitoring is also used to precisely localize the epileptogenic focus in patients who are candidates for epilepsy surgery.

• The UH Electroneurodiagnostics (END) Lab: Provides comprehensive testing of the electrical activity of the brain and nervous systems. The lab is equipped with electroencephalogram (EEG), continuous video EEG monitoring and evoked potentials. We also offer technology used for monitoring EEG or evoked potentials during surgery for brain or spinal cord tumor, trauma, aneurysm, vascular malformations or blockage, congenital abnormalities, spinal cord malformations, epilepsy surgery and movement disorders.

• Epilepsy Transition Clinic: In collaboration with the Epilepsy Center at UH Rainbow Babies & Children’s Hospital, the Epilepsy Transition Clinic provides continuity of care as adolescent epilepsy patients transition to adult care. The clinic is comprised of both adult and pediatric epileptologists and is designed to create a seamless transition of care to patients entering adulthood who have continuing medical issues. The primary objectives of this teenager clinic are to address the unique needs and concerns of this age group and, importantly, to facilitate a smooth handover of specialist epilepsy care from pediatric to adult services.

• Intra-operative monitoring (IOM): Provides comprehensive monitoring of evoked potentials and other neurophysiologic parameters during surgery to immediately identify changes in brain, spinal cord and peripheral nerve function prior to irreversible damage. IOM also is effective in localizing anatomical structures, including peripheral nerves and sensorimotor cortex, which helps guide the surgeon during dissection.

Specialized equipment:• 4 Tesla MRI

• Functional MRI

• Intracarotid amobarbital testing

• Ictal SPECT scans

• Mapping of seizure onset zones

• PET scans

• Specialized MRI epilepsy-specific imaging protocols

EPILEPSY CENTER

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EPILEPSY CENTER

Samden Lhatoo, MDOffice Phone: 216-844-5855Appointment Phone: 216-844-2724

Special Interests: Epilepsy, Neurophysiology

Sees Patients at: UH Case Medical Center, UH Ahuja Medical Center

Hans O. Lüders, MDOffice Phone: 216-844-3650Appointment Phone: 216-844-2724

Special Interests: Clinical Neurophysiology, Higher Cortical Functions, EEG – Electroencephalography, Epilepsy, Language Mapping

Sees Patients at: UH Case Medical Center

Shahram Amina, MDOffice Phone: 216-844-3675Appointment Phone: 216-844-2724

Special Interest: Epilepsy

Sees Patients at: UH Ahuja Medical Center, UH University Suburban Health Center

Fareeha Ashraf, MDOffice Phone: 216-844-3192Appointment Phone: 216-844-2724

Special Interests: Epilepsy, Sleep Medicine, Hypersomnia, Sleep Apnea, Sleep Related Movement Disorder, Sleep Breathing Disorders

Sees Patients at: UH Case Medical Center, UH Ahuja Medical Center

Michael W. Devereaux, MDOffice Phone: 216-844-3591Appointment Phone: 216-844-2724

Special Interests: Multiple Sclerosis, Epilepsy, General Neurology, Neuro-ophthalmology

Sees Patients at: UH Case Medical Center, UH Ahuja Medical Center, UH Richmond Medical Center, UH University Suburban Health Center, UH Geneva Medical Center, UH Medina Health Center

Matthew Eccher, MD, MSPHOffice Phone: 216-844-1764Appointment Phone: 216-844-2724

Special Interests: Epilepsy, Disorders of Consciousness, Clinical Neurophysiology

Sees Patients at: UH Case Medical Center, UH Ahuja Medical Center, UH University Suburban Health Center

Pamela Lang, CNSOffice Phone: 216-844-5383Appointment Phone: 216-844-2724

Special Interest: Epilepsy

Sees Patients at: UH Case Medical Center, UH University Suburban Health Center

Joseph A. Locala, MDOffice Phone: 216-844-2400Appointment Phone: 216-844-2400

Special Interests: Adult Psychiatry, Psychosomatic Psychiatry, Psychiatric Care of Medically Ill Patients, Transplant Psychiatry, Mood Disorders in the Medically Ill, Anxiety Disorders in the Medically Ill

Sees Patients at: UH Case Medical Center, UH Seidman Cancer Center, W.O. Walker Center

Jonathan Miller, MDOffice Phone: 216-844-3470Appointment Phone: 216-844-2724

Special Interest: Epilepsy Surgery

Sees Patients at: UH Case Medical Center

Jennifer Sweet, MDOffice Phone: 216-983-3334Appointment Phone: 216-844-2724

Special Interest: Epilepsy Surgery

Sees Patients at: UH Case Medical Center

Tanvir U. Syed, MDOffice Phone: 440-827-5061Appointment Phone: 216-844-2724

Special Interests: Intraoperative Monitoring, Epilepsy, Language Mapping, Higher Cortical Functions, Pseudoseizures, Outcomes Research, Biostatistics, Psychogenic Nonepileptic Seizures

Sees Patients at: UH Westlake Health Center, St. John Medical Center, UH Medina Health Center

Epilepsy Center at UH Rainbow Babies & Children’s Hospital University Hospitals Rainbow Babies & Children’s Hospital is

a national leader in pediatric epilepsy diagnosis, treatment

and management. With a focus on helping patients enjoy

a healthy and seizure-free life, our pediatric epilepsy team

delivers comprehensive, family-centered care to infants,

children and teens.

Accurate diagnosisComprehensive assessments and state-of-the-art tests, including an inpatient pediatric video EEG monitoring unit and high-resolution MRI, PET and SPECT imaging technologies, accurately diagnose new onset seizures, spells that mimic seizures and epileptic disorders due to many different causes.

Best practices in pediatric epilepsy managementIndividualized approach to patient care incorporates specialized programs, newer medications, advanced surgery and other innovative therapies – all closely monitored by pediatric epileptologists, neurosurgeons and epilepsy nurses.

Surgical therapyPediatric epileptologists perform an extensive presurgical evaluation with modern invasive electrode technology and work with experienced pediatric neurosurgeons, radiologists, neuropsychologists and psychiatrists to treat seizures with specialized and individually tailored brain surgery.

Level IV Pediatric Epilepsy CenterRecognized with the highest level designation by the National Association of Epilepsy Centers.

Convenient accessOutpatient services provided at community locations across the region and an expert call center that guides medication adjustments to reduce side effects and improve outcomes.

New Onset Seizure ClinicThe new onset seizure clinic provides expert diagnostic services, referrals, treatment and follow-up care for children who experience a first seizure. The outpatient program offers rapid access to care, and was developed as part of the hospital’s increased focus on pediatric neurology and epilepsy. The key to effectively treating children with seizures starts with an accurate diagnosis. This includes imaging the brain and performing EEG testing to record brain activity. This helps to confirm the diagnosis, identify the cause of seizures and initiate appropriate treatment with medications. We counsel patients on safety issues and behaviors that may reduce the risk for further seizures. Neuropsychologic screening is available to screen for possible academic and behavior problems. We offer and develop individualized care plans for children who have experienced new onset seizures.

Jonathan Miller, MDOffice Phone: 216-844-3470Appointment Phone: 216-844-2724

Special Interests: Pain Neurosurgery, Movement Disorders Surgery, Cancer Pain, Facial Pain, Peripheral Nerve Surgery, Stereotatic & Functional Neurosurgery, Epilepsy Surgery, Gamma Knife® Stereotactic Radiosurgery, Neuro-oncology

Sees Patients at: UH Case Medical Center

Asim Shahid, MDOffice Phone: 216-286-3691Appointment Phone: 1-866-UH4-PEDS

Special Interests: Electroencephalography, Pediatric Epilepsy, Pediatric Neurology

Sees Patients at: UH Rainbow Babies & Children’s Hospital, UH Landerbrook Health Center, UH Westlake Health Center

Jun Park, MDOffice Phone: 216-286-6644Appointment Phone: 1-866-UH4-CARE

Special Interests: Intractable Epilepsy, Cortical Dysplasia, Tuberous Sclerosis, Neonatal Stroke, Infantile Spasms, Seizures in Infancy, Post-traumatic Epilepsy, Vagal Nerve Stimulation

Sees Patients at: UH Rainbow Babies & Children’s Hospital

Rachel B. Tangen, PhDOffice Phone: 216-844-3230Appointment Phone: 1-866-UH4-CARE

Special Interests: Neuropsychology, Pediatric Brain Disease, Brain Injury, Neuropsychological/ Learning Evaluations, Seizure Disorders, Cochlear Implantation

Sees Patients at: W.O. Walker Center

EPILEPSY CENTER

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UH Neurological Institute’s Functional & Restorative

Neurosurgery Center is dedicated to the restoration

of function affected by neurological disease and the

development of new technologies to improve brain health.

The center is focused on the electrical or pharmacologic modification of neurological activity through neuromodulation therapies, including alterations of nerve function through electrical stimulation or ablation and direct delivery of medication to the nervous system. These advanced procedures provide options for patients with conditions and symptoms that aren’t responding optimally to standard medical management.

The primary surgical treatment for restoring neurological function is deep brain stimulation (DBS). However, our nationally recognized neurosurgeons also perform a wide variety of restorative procedures including vagal nerve stimulation and targeted cranial surgical resections for the treatment of refractory epilepsy, spinal cord and peripheral nerve stimulation, surgical treatment of facial pain, stereotactic radiosurgery and intrathecal drug delivery.

Conditions treated:• Chronic neuropathic pain

Trigeminal neuralgiaFailed back surgery syndrome (postlaminectomy)Chronic regional pain syndrome/reflex sympathetic dystrophyOccipital neuralgiaAnesthesia dolorosaDeafferentation pain (brachial plexus avulsion, cancer pain)

• EpilepsyMedically refractory epilepsy (adult and pediatric)Neuromodulation for epilepsy

• Movement disordersEssential tremorParkinson’s diseaseCervical dystoniaGeneralized dystonia

• Peripheral nerve disordersEntrapment neuropathy (carpal tunnel, ulnar neuropathy, peroneal neuropathy)Post-herniorraphy ilioinguinal neuralgiaPeripheral nerve tumorsPeripheral nerve trauma (brachial plexus, nerve injuries)

• PsychosurgeryObsessive-compulsive disease

• SpasticityCerebral palsyMultiple sclerosisSpastic hemiplegia/paraplegia/tetraplegia due to stroke or trauma

Innovations:• First in North America to perform DBS of the thalamus to treat

symptoms of Tourette syndrome successfully.

• The first group worldwide to complete a prospective randomized double blinded trial of thalamic DBS for Tourette syndrome in a pilot clinical trial of five patients.

Programs:• Deep Brain Stimulation: Manages tremors, movement and walking

problems via surgical implantation of electrodes in the brain and pulse generators in the upper chest just beneath the collarbones.

• Spinal Cord Stimulation: Uses spinal cord neurostimulators that deliver targeted chronic pain management. The neurostimulator is inserted under the skin through a small incision in the upper buttock, while the long-term lead is implanted in the epidural space of the spinal cord.

• Intrathecal Drug Delivery: Also known as the “pain pump” or “baclofen pump,” this simple procedure uses a small pump to deliver medication directly to your spinal cord. The pump is surgically placed under the abdominal skin and delivers medication through a catheter to the area around your spinal cord. Effective in treating chronic pain and spasticity.

• Surgical Treatment of Epilepsy: Seizures that do not respond to pharmaceutical management may be reduced or eliminated through epilepsy surgery. Advances in presurgical diagnostic techniques, including brainmapping, expand therapeutic options to a larger percentage of epileptic patients.

• Surgical Treatment of Facial Pain: Accurately identifies source of pain before devising customized surgical treatments. Surgical solutions are available to relieve pain associated with trigeminal neuralgia, multiple sclerosis, tumors and a variety of other neuropathies.

• Pediatric Neurosurgery: Our expert neurosurgeons are skilled in the latest approaches and use the latest technologies to provide customized surgical solutions to pediatric patients with a wide variety of neurological conditions.

Current clinical trials:• BrainGate2. Feasibility Study of an Intracortical Neural Interface

System for Persons with Tetraplegia. Obtain preliminary device safety information and demonstrate proof of principle (feasibility of efficacy) of the ability of people with tetraplegia to control a computer cursor and other assistive devices with their thoughts. Prospective, open-label, feasibility study. Primary Endpoint: Safety: Sensor successfully implanted, not explanted for safety reasons during the one-year post-implant evaluation, and there are no device-related Serious Adverse Events which result in death or permanently increased disability during the one-year post-implant evaluation period.

FUNCTIONAL & RESTORATIVE NEUROSURGERY CENTER

Jonathan Miller, MDOffice Phone: 216-844-3470Appointment Phone: 216-844-2724

Special Interests: Pain Neurosurgery, Movement Disorders Surgery, Facial Pain, Peripheral Nerve Surgery, Stereotatic & Functional Neurosurgery, Epilepsy Surgery, Gamma Knife® Stereotactic Radiosurgery

Sees Patients at: UH Case Medical Center

Mirza Baig, MDOffice Phone: 216-286-6486Appointment Phone: 1-866-UH4-CARE

Special Interests: Physical Medicine, Rehabilitation

Sees Patients at: UH Case Medical Center, UH Rehabilitation Hospital

Bashar Katirji, MDOffice Phone: 216-844-4854Appointment Phone: 216-844-2724

Special Interests: Peripheral Nerve Disorders, Neuromuscular Disorders, Amyotrophic Lateral Sclerosis, Myasthenia Gravis, Entrapment Neuropathies, Electrodiagnosis, EMG

Sees Patients at: UH Case Medical Center, UH AhujaMedical Center, UH University Suburban Health Center

Samden Lhatoo, MDOffice Phone: 216-844-5855Appointment Phone: 216-844-2724

Special Interests: Epilepsy, Neurophysiology

Sees Patients at: UH Case Medical Center,UH Ahuja Medical Center

David Ryan, MDOffice Phone: 440-816-2850Appointment Phone: 440-816-2850

Special Interests: Anesthesiology, Pain Management, Interventional Treatments Including Radio Frequency and Ablation, Neuromodulation for Cervicogenic and Migraine Headache, Infusion Therapies, Sympathetic Mediated Pain

Sees Patients at: Southwest General Health Center

Asim Shahid, MDOffice Phone: 216-286-3691Appointment Phone: 1-866-UH4-PEDS

Special Interests: Electroencephalography, Pediatric Epilepsy, Pediatric Neurology

Sees Patients at: UH Rainbow Babies & Children’s Hospital, UH Landerbrook Health Center, UH Westlake Health Center

Barbara E. Shapiro, MD, PhDOffice Phone: 216-844-7768Appointment Phone: 216-844-2724

Special Interests: Lysosomal Disorders, EMG, Tay-Sachs Disease, Peripheral Neuropathy, Metabolic & Muscular Dystrophy, Neuromuscular Disorders

Sees Patients at: UH Case Medical Center,UH Ahuja Medical Center

Jennifer Sweet, MDOffice Phone: 216-983-3334Appointment Phone: 216-844-2724

Special Interests: Pain Neurosurgery, Movement Disorders Surgery, Cancer Pain, Facial Pain, Peripheral Nerve Surgery, Stereotatic & Functional Neurosurgery, Epilepsy Surgery, Gamma Knife®, Stereotactic Radiosurgery, Neuro-oncology

Sees Patients at: UH Case Medical Center

Benjamin L. Walter, MDOffice Phone: 216-844-8285Appointment Phone: 216-844-2724

Special Interests: Dystonia, Tremors, Movement Disorders, Functional Magnetic Resonance Imaging (MRI), Mechanisms of Effect of DBS, Deep Brain Stimulation, Parkinson’s Disease

Sees Patients at: UH Case Medical Center,UH University Suburban Health Center,UH Medina Health Center, UH Westlake Health Center

FUNCTIONAL & RESTORATIVE NEUROSURGERY CENTER

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MUSIC & MEDICINE CENTER

Recognizing that musicians often develop unique medical

problems that can be devastating to their musical abilities and

careers, the UH Neurological Institute established the Music

& Medicine Center. Clinical trials, specialized equipment,

and innovative treatment options make UH Case Medical

Center uniquely qualified to correctly diagnose and manage

music-related injuries. A full range of patient services relevant

to music-related medical problems is available through the

Music & Medicine Wellness Program.

UH Case Medical Center and Case Western Reserve University School of Medicine collectively have physician-scientists covering the entire spectrum of care, from perception of music, speech and voice, to memory and motor performance.

Musician wellness program and treatment of music-related injuries:• Tinnitus

• Musculoskeletal disorders

• Dizziness

• Voice and throat disorders

• Hearing loss

• Pulmonary disorders

• Depression

• Memory loss

• Visual loss

Neuromuscular disorders:• Overuse Syndrome

• Neural Impingement

• Focal Dystonia

Psychiatric disorders:• Anxiety

• Bipolar Disorder

• Depression & Substance Use

Otological disorders:• Hearing Loss

• Tinnitus & Vertigo

Laryngological disorders:• Laryngitis

• Voice Disturbance

• Aphonia

Michael DeGeorgia, MDOffice Phone: 216-844-1552Appointment Phone: 216-844-2724

Special Interests: Critical Care Bioinformatics, Hemorrhagic Stroke, Hypothermia, ICU Monitoring, Ischemic Stroke, Neurocritical Care

Sees Patients at: UH Case Medical Center

Jonathan Lass, MDOffice Phone: 216-844-8590Appointment Phone: 216-844-3601

Special Interests: Cataract and Lens Implant Surgery, Corneal and External Diseases, Corneal Transplantation, Eye Exams, Eye Injury, Eye Trauma, Intra-ocular Lenses, IOL, Ophthalmology, Vision Exams

Sees Patients at: UH Case Medical Center, UH Landerbrook Health Center, UH Lyndhurst Surgery Center

Alan J. Lerner, MDOffice Phone: 216-464-6412Appointment Phone: 216-464-6445

Special Interests: Alzheimer’s Disease, Dementia, Behavioral Neurology, General Neurology, Higher Cortical Functions, Adult Attention Deficit Disorder (adult ADD/ADHD)

Sees Patients at: UH Ahuja Medical Center, UH Foley ElderHealth Center

Hans O. Lüders, MDOffice Phone: 216-844-3650Appointment Phone: 216-844-2724

Special Interests: Clinical Neurophysiology, EEG – Electroencephalography, Epilepsy, Higher Cortical Functions, Language Mapping

Sees Patients at: UH Case Medical Center

Nicole Maronian, MDOffice Phone: 216-983-3455 Appointment Phone: 216-844-2724

Special Interests: Ear, Nose & Throat, Head and Neck Cancer, Otolaryngology, Voice and Swallowing Disorders

Sees Patients at: UH Case Medical Center

Cliff A. Megerian, MDOffice Phone: 216-844-5500Appointment Phone: 216-844-6000

Special Interests: Hearing Loss, Otitis, Chronic Ear Disease, Surgery for Hearing Loss and Tumor, Vertigo, Meniere’s Disease, Dizziness, Neurotology, Skull Based Surgery, Acoustic Neuromas

Sees Patients at: UH Case Medical Center, UH Chagrin Highlands Health Center, UH Westlake Health Center

Jonathan Miller, MDOffice Phone: 216-844-3470Appointment Phone: 216-844-2724

Special Interests: Pain Neurosurgery, Movement Disorders Surgery, Cancer Pain, Facial Pain, Peripheral Nerve Surgery, Stereotatic & Functional Neurosurgery, Epilepsy Surgery, Gamma Knife® Stereotactic Radiosurgery, Neuro-oncology

Sees Patients at: UH Case Medical Center

Gail Murray, PhD, MEdOffice Phone: 216-844-8168Appointment Phone: 216-844-7191

Special Interests: Pediatric Audiology, Central Audiotory Processing, Cochlear Implantation

Sees Patients at: UH Rainbow Babies & Children’s Hospital, UH Chagrin Highlands Health Center

David C. Preston, MDOffice Phone: 216-844-7776Appointment Phone: 216-844-2724

Special Interests: Neuromuscular Disorders, Electrophysiology, Myasthenia Gravis, Entrapment Neuropathies, Peripheral Neuropathies, Peripheral Nerve Disorders

Sees Patients at: UH Case Medical Center, UH University Suburban Health Center, UH Richmond Medical Center

Robert J. Ronis, MD, MPHOffice Phone: 216-844-3883Appointment Phone: 216-844-3883

Special Interests: Community Psychiatry, Adult Ambulatory, Psychopharmacology, Chemical Dependency, Psychotherapy, Addiction Psychiatry, Community Mental Health

Sees Patients at: W.O. Walker Center

Robert Schilz, DO, PhDOffice Phone: 216-844-3201Appointment Phone: 216-844-7200

Special Interests: Bronchoscopy, Critical Care, Lung Transplantation, Pulmonary Vascular Disease

Sees Patients at: UH Case Medical Center

Maroun Semaan, MDOffice Phone: 216-844-8013Appointment Phone: 216-844-6000

Special Interests: Cochlear & Brainstem Implants, Facial Nerve & Balance Disorders, Hearing, Neuro Fibromatosis Type II, Skull Base Surgery

Sees Patients at: UH Case Medical Center, UH Chagrin Highlands Health Center, UH Twinsburg Health Center, UH Seidman Cancer Center – Westlake

Barbara E. Shapiro, MD, PhDOffice Phone: 216-844-7768Appointment Phone: 216-844-2724

Special Interests: Lysosomal Disorders, Tay-Sachs Disease, Peripheral Neuropathy, Metabolic & Muscular Dystrophy, Neuromuscular Disorders

Sees Patients at: UH Case Medical Center, UH Ahuja Medical Center

Benjamin L. Walter, MDOffice Phone: 216-844-8285Appointment Phone: 216-844-2724

Special Interests: Dystonia, Tremors, Movement Disorders, Functional Magnetic Resonance Imaging (MRI), Mechanisms of Effect of DBS, Deep Brain Stimulation, Parkinson’s Disease

Sees Patients at: UH Case Medical Center, UH University Suburban Health Center, UH Medina Health Center, UH Westlake Health Center

MUSIC & MEDICINE CENTER

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NEUROCRITICAL CARE CENTER

UH Neurological Institute’s world-renowned Neurocritical

Care Center is one of only a few available in Ohio

and provides continuous state-of-the-art monitoring

and treatment for patients who are critically ill, need

postoperative care or require intensive neurological

monitoring. The Neurocritical Care Center is a dedicated,

multidisciplinary center structured to provide the best

patient care and improve communication and coordination

of research, while promoting education and advanced

administrative efficiency. It is the only such center for

neurocritical care in the Midwest.

Hospital staff at UH Case Medical Center as well as our community hospitals receive continuous training in the latest, most effective techniques and technology to benefit patient treatment. Studies show that involvement of a dedicated neurological intensive care team correlates to a significant reduction in length-of-stay and controlled cost and, most importantly, a reduction of in-hospital mortality and better patient outcomes.

Conditions treatedNeurocritical care is comprehensive multisystem care of the critically ill neurological patient. In the NSU, we care for a broad spectrum of patients including postoperative neurosurgical patients and patients with massive ischemic stroke, status epilepticus, encephalitis and neuromuscular respiratory failure, as well as trauma, intracerebral hemorrhage and subarachnoid hemorrhage.

ProgramsPediatric Neurosurgery: Our expert neurosurgeons are skilled in the latest approaches and use the latest technologies to provide customized surgical solutions to pediatric patients with a wide variety of trauma-related conditions.

InnovationsUniversity Hospitals created the world’s first neurological intensive care medicine practice nearly three decades ago. We literally “wrote the book” on neurocritical care (our textbook, Critical Care Neurology and Neurosurgery, is the standard textbook of the field). UH is one of 25 institutions in the United States that offers a fellowship in Neurocritical Care and our annual international CME conference is the benchmark meeting for the field.

University Hospitals is a world leader when it comes to heart and brain resuscitation after cardiac arrest. In fact, George Crile, MD, former Professor and Chief of Surgery at University Hospitals, was the first to successfully use external chest compression in 1903 and the first to use adrenaline (epinephrine) in resuscitation in 1909. Claude Beck, MD, Professor of Cardiothoracic Surgery, is credited with performing the first successful cardiac defibrillation in humans in 1947 and introduced the first CPR course for the lay public in 1958.

Continuing with this strong tradition, University Hospitals was one of the first institutions to adopt hypothermia after cardiac arrest to protect the brain from damage. We have been working closely with Cleveland EMS to cool patients as early as possible to achieve the best possible outcome. Michael DeGeorgia, MD, Director of the Neurocritical Care Center, is one of the world’s leading authorities in hypothermia.

Case Critical Care Bioinformatics Consortium: We believe the future of intensive care monitoring lies in:

(1) Integration and time-synchronization of multiple channels of physiological data continuously and simultaneously

(2) Processing of this data in real-time, using new tools such as multivariate analysis and nonlinear time series analysis

(3) Presenting this data to the clinician using innovative and intuitive clinician-centric visual displays

Special equipmentWe review minute-to-minute progress with the most advanced monitoring equipment in the world, including:

• Brain tissue oxygenation monitoring

• Cerebral blood flow monitoring

• Continuous video EEG monitoring

• CT angiography and CT perfusion studies

• Intracranial pressure monitoring

• MRI perfusion – diffusion imaging

• Positron Emission Tomography (PET)

• Transcranial Doppler (TCD) ultrasonography

These monitoring capabilities are combined with the latest interventions to save brain function, including:

• Burst suppression

• Cerebral angiography and intervention (angioplasty, stenting)

• Endovascular coiling

• Induced hypertension (Hypertensive hypervolemic hemodilution)

• Induced hypothermia

• Intravenous and intra-arterial thrombolysis

• Plasmapheresis

• Ventricular drainage

Mission of the center: • To improve patient care by implementing best medical

practices for acute neurological disorders. To foster clinical, experimental, and outcomes research focused on developing innovative interventions. To improve education of residents and fellows by developing standards for training in neurocritical care. To advance administrative efficiency and quality improvement. To deliver nursing care in a manner that promotes interdisciplinary collaboration, caring and compassion.

• To strive to be the world leader in neurocritical care.

Michael DeGeorgia, MDOffice Phone: 216-844-1552Appointment Phone: 216-844-2724

Special Interests: Critical Care Bioinformatics, Hemorrhagic Stroke, Hypothermia, ICU Monitoring, Ischemic Stroke, Neurocritical Care

Sees Patients at: UH Case Medical Center

Ciro Estabenez, MDOffice Phone: 216-844-3192

Appointment Phone: 216-844-2724

Special Interests: General Neurology, Neuromuscular

Disorders, Neurocritical Care, Stroke

Sees Patients at: UH Case Medical Center

Seth Alan Hoffer, MDOffice Phone: 216-844-5744Appointment Phone: 216-844-2724

Special Interests: Neurocritical Care, Spine Surgery

Sees Patients at: UH Case Medical Center, UH Richmond Medical Center, UH Bedford Medical Center

Wei Xiong, MDOffice Phone: 216-844-0474Appointment Phone: 216-844-2724

Special Interests: Stroke, Hypothermia, Neurocritical Care, Cardiac Arrest

Sees Patients at: UH Geauga Medical Center

NEUROCRITICAL CARE CENTER

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UH Neurological Institute’s Neurological & Behavioral

Outcomes Center is one of the first centers of its kind

in the United States devoted exclusively to studying

outcomes and quality improvements in patients with

neurological conditions.

By establishing the center, the UH Neurological Institute is creating an infrastructure to accurately evaluate patient outcomes, refine performance improvement processes and increase health care value.

Contributions to neuroscienceThe Neurological & Behavioral Outcomes Center identifies, develops and assists with implementing methods and approaches that incorporate the latest education and research to deliver the highest value health care to patients with neurological disorders.

The center is committed to health promotion approaches that have the potential to advance health outcomes for patients with neurological and neuropsychiatric conditions. The Neurological & Behavioral Outcomes Center infrastructure is designed to generate new research and to help investigators shape their ideas into proposals and grant applications. Working with investigators from a variety of other local, regional, national and international research groups, center researchers have led and/or collaborated on projects covering a broad range of neuroscience topics. Collaborators include faculty at the Case Western Reserve University School of Medicine and School of Arts and Sciences, the Francis Payne Bolton School of Nursing, the Veterans Health Administration, MetroHealth Medical Center, the Case Western Reserve University Prevention Research Center, the Cleveland Clinic, University of Pennsylvania, University of Toronto, the Parkinson’s Research Institute in Milwaukee, Wis., The Ohio State University and Kent State

University. Recognizing the critical importance of preliminary data to continue a robust research trajectory, the Neurological & Behavioral Outcomes Center is also involved in pilot projects intended to support the submission of future grant applications, and to inform improvements in UH Neurological Institute clinical programming. Center researchers through Case Western Reserve University School of Medicine receive research funding from the National Institutes of Health (NIH), the Centers for Disease Control (CDC), National Science Foundation (NSF), national and regional foundations as well as industry and patient/consumer advocacy associations.

Focused on education, center faculty are engaged in mentoring junior UH Neurological Institute investigators and students in various stages of their research careers. Recently, the Neurological & Behavioral Outcomes Center faculty began leading the U.S.-based component of an NIH Medical Education Partnership Initiative to develop clinical and research training in neurological disorders in Uganda, Africa. Faculty are also active in teaching colleagues by speaking locally and internationally.

The center is also supported by an NIH Clinical and Translational Science Award (CTSA) to Case Western Reserve University School of Medicine. The university is one of 38 medical research institutions working together as a national consortium to improve the way biomedical research is conducted across the country. The consortium shares a common vision of reducing the time it takes for laboratory discoveries to become treatments for patients and to engage communities in clinical research efforts.

Martha Sajatovic, MDOffice Phone: 216-844-2808, 216-368-7572Appointment Phone: 216-844-2400

Special Interests: Adult Psychiatry, Geropsychiatry, Geriatric Psychiatry, Health Services, Bipolar Disorder, Treatment Adherence

Sees Patients at: W.O. Walker Center

NEUROLOGICAL & BEHAVIORAL OUTCOMES CENTER

UH Neurological Institute’s Neuromuscular Center has

established itself as one of America’s foremost institutions

for the treatment of complex neuromuscular disorders

by combining extensive clinical experience for a wide

variety of specialties.

UH provides diverse testing, diagnosis and treatment labs to address the full range of neuromuscular conditions. Labs are available at many community facilities and offer:

• Autonomic Laboratory: As one of only 12 such labs in the country, we test all aspects of autonomic function including cardiac, vasomotor and sudomotor (sweat) functions; and to diagnose chronic regional pain syndrome, peripheral neuropathies, Postural Orthostatic Tachycardia Syndrome (POTS) and syncope of unknown etiology. It provides full support in the assessment of patients seen in the interdisciplinary program clinics.

• Electromyography (EMG) Lab: The EMG Lab provides high-quality, state-of-the-art electrodiagnostic testing of neuromuscular disorders. The EMG test includes nerve conduction studies performed by the EMG technologists under physician supervision and the muscle needle examination performed by the EMG physician. Computerized EMG machines are available at all six EMG lab locations within the UH system. These machines enable lab personnel to perform detailed electrodiagnostic testing on every patient with instant report generation. Highly specialized testing such as single fiber EMG and quantitative testing are also offered.

Surgical solutions:• Diaphragmatic pacing for high cervical spinal cord injury and

patients with amyotrophic lateral sclerosis

Conditions treatedNeuromuscular conditions treated include:

• Amyotrophic lateral sclerosis (ALS)

• Cervical and lumbar radiculopathy

• Chronic inflammatory demyelinating polyneuropathy (CIDP)

• Entrapment neuropathies

• Guillain-Barre syndrome

• Muscular dystrophies

• Myasthenia gravis

• Peripheral neuropathy

• Polymyositis/Dermatomyositis

Autonomic conditions treated include:

• Orthostatic hypotension

• Syncope

• Small fiber neuropathies

• Postural tachycardia syndrome (POTS)

• Multiple system atrophy

• Hyperhidrosis

Current clinical trialsClinical research is a cornerstone in the treatment options Neuromuscular Center physicians offer to patients. Our physicians and scientists contribute to:

• ICEPAC NIH Grant: (Interstitial Cystitis Evaluation of Psychophysiologic and Autonomic Characteristics) – to understand the role of the nervous system in this debilitating chronic pain disorder, as well as in another pelvic pain disorder called myofascial pelvic pain syndrome.

The Neuromuscular Center is one of only a few nationwide participating in an NIH-Funded Trial testing the efficacy of thymectomy in the treatment of myasthenia gravis.

ProgramsFor the proper development of personalized patient treatment plans, the Neuromuscular Center has designated leading-edge diagnostic and treatment programs:

• Autonomic Disorders Interdisciplinary Program: This program provides interdisciplinary clinics for diagnosis and treatment for adults and children with mysterious episodes of dizziness, fainting, vomiting or unexplained stomach pain. Physicians also address complex regional pain syndrome, unexplained or unmanaged pain in the pelvic region and issues of excessive sweating or other sweat or flushing related issues.

• Amyotrophic Lateral Sclerosis (ALS) Program: This nationally renowned program takes an interdisciplinary approach by combining strengths of specialists from the Neuromuscular Center, pulmonary medicine, speech pathology and nutrition to manage the symptoms and treatment for each patient. UH uses diaphragmatic stimulation and pacing to help patients breathe and speak more normally, and it helps stave off respiratory complications during the progression of ALS.

NEUROMUSCULAR CENTER

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NEUROMUSCULAR CENTER

Autonomic Lab ProgramThe Neuromuscular Center’s Autonomic Lab Program performs four different types of tests depending on the diagnosis of the referring physician:

• Autonomic Screen

• Reflex Sympathetic Dystrophy/Chronic Regional Pain Syndrome Screen

• Quantitative Sensory Test

• Thermoregulatory Sweat Test

• Myasthenia Gravis Program: For over a decade, patients have been treated with immunosuppressive drugs as well as plasma exchange and intravenous immunoglobulin.

• Muscular Disease Program: This program brings a multidisciplinary approach to the diagnosis and management of patients with inherited neuromuscular disorders, including muscular dystrophies and peripheral neuropathies, as well as acquired conditions such as postpolio-myelitis syndrome and inclusion body myositis.

Patient conveniencePerhaps the most significant benefit to patients is that they have access to expert consultation and advanced diagnostics close to home in our community facilities. In addition to the main UH Case Medical Center campus, our renowned specialists see patients at UH Bedford Medical Center, UH Richmond Medical Center, UH University Suburban Health Center and UH Westlake Health Center.

Same-Day EMG Services AvailableThe UH Neurological Institute announces the availability of same-day service for Nerve Conduction Studies and Electromyography (EMG) for your patients with suspected entrapment neuropathies, radiculopathies, peripheral neuropathies, and other complex nerve, muscle, anterior horn cell and NMJ disorders. To schedule a same-day EMG, call 216-844-1923.

Advanced diagnostic screening is available at:EMG Lab

UH Case Medical Center

UH Ahuja Medical Center

UH University Suburban Health Center

UH Westlake Health Center

Autonomic Lab

UH Case Medical Center

UH Ahuja Medical Center

UH Westlake Health Center

The Neuromuscular Center operates the first Diaphragmatic Pacing Center in the world. This center evaluates patients with spinal cord injury, ALS and other neurological disorders with early respiratory failure who may be candidates for diaphragm pacing systems..

Bashar Katirji, MDOffice Phone: 216-844-4854Appointment Phone: 216-844-2724

Special Interests: Peripheral Nerve Disorders, Neuromuscular Disorders, Amyotrophic Lateral Sclerosis, Myasthenia Gravis, Entrapment Neuropathies, Electrodiagnosis, EMG

Sees Patients at: UH Case Medical Center, UH Ahuja Medical Center, UH University Suburban Health Center

Marek A. Buczek, MD, PhDOffice Phone: 440-250-5303Appointment Phone: 216-250-5303

Special Interests: General Neurology, Electrophysiology, Headache, Chronic Pain Syndromes, EMG, Head Injury

Sees Patients at: UH Case Medical Center, UH Westlake Health Center, St. John Medical Center

All National Institute of Health (NIH) funding for basic and clinical research is awarded to the School of Medicine at Case Western Reserve University.

Brian Dyko, NPOffice Phone: 216-844-3495Appointment Phone: 216-844-3192

Special Interests: Autonomic Disorders, General Neurology, Headache, Memory & Cognition, Neuromuscular

Sees patients at: UH Case Medical Center, UH Westlake Health Center, UH Foley ElderHealth Center

Mary Jo Elmo, CNPOffice Phone: 216-844-8594

Special Interest: Diaphragm Pacing System Referral

Sees Patients at: UH Case Medical Center

Gerald E. Grossman, MDOffice Phone: 216-844-8925Appointment Phone: 216-844-2724

Special Interests: Neuromuscular Disorders, EMG

Sees Patients at: UH Case Medical Center, UH Ahuja Medical Center

Jeff Janata, PhDOffice Phone: 216-844-8550Appointment Phone: 216-844-8550

Special Interests: Autonomic Disorders, Behavior Therapy, Behavioral Medicine, Cognitive Behavioral Psychotherapy, Health Psychiatry, Health Psychology, Pain Management

Sees Patients at: UH MacDonald Women’s Hospital, W.O. Walker Center

Joseph A. Locala, MDOffice Phone: 216-844-2400Appointment Phone: 216-844-2400

Special Interests: Adult Psychiatry, Psychosomatic Psychiatry, Psychiatric Care of Medically Ill Patients, Transplant Psychiatry, Mood Disorders in the Medically Ill, Anxiety Disorders in the Medically Ill

Sees Patients at: UH Case Medical Center, UH Seidman Cancer Center, W.O. Walker Center

Daniel W. Miller, MDOffice Phone: 216-844-7380Appointment Phone: 216-844-3192

Special Interests: General Neurology, Neuromuscular Disorders, Neurophysiology, EMG

Sees Patients at: UH Case Medical Center, UH University Suburban Health Center

Raymond P. Onders, MDOffice Phone: 216-844-5797Appointment Phone: 216-844-7874

Special Interests: Minimally Invasive Surgery, General Surgery, Diaphragm Pacing, Anti-Reflux Surgery

Sees Patients at: UH Case Medical Center, UH University Suburban Health Center, UH Westlake Health Center

David C. Preston, MDOffice Phone: 216-844-7776Appointment Phone: 216-844-2724

Special Interests: Neuromuscular Disorders, Electrophysiology, Myasthenia Gravis, EMG, Entrapment Neuropathies, Peripheral Neuropathies, Peripheral Nerve Disorders

Sees Patients at: UH Case Medical Center, UH University Suburban Health Center, UH Richmond Medical Center

Jenice Robinson, MDOffice Phone: 216-844-3495Appointment Phone: 216-844-2724

Special Interests: Amyotrophic Lateral Sclerosis (ALS), Autonomic Disorders, Neuromuscular Disorders, Electromyography

Sees Patients at: UH Case Medical Center, UH Ahuja Medical Center

Barbara E. Shapiro, MD, PhDOffice Phone: 216-844-7768Appointment Phone: 216-844-2724

Special Interests: Lysosomal Disorders, EMG, Tay-Sachs Disease, Peripheral Neuropathy, Metabolic & Muscular Dystrophy, Neuromuscular Disorders

Sees Patients at: UH Case Medical Center, UH Ahuja Medical Center

Leonard Weinberger, MDOffice Phone: 440-357-3100Appointment Phone: 440-357-3100

Special Interests: General Neurology, Parkinson’s Disease, EMG

Sees Patients at: UH Concord Health Center

NEUROMUSCULAR CENTER

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NEUROPSYCHIATRY CENTER

UH Neurological Institute’s Neuropsychiatry Center treats

co-occurring disorders in adults and pediatric patients.

This cross-functional treatment plan works for psychiatric

syndromes ranging from adjustment disorders, to depression

or anxiety, to a primary medical illness or to an underlying

mood or anxiety disorder that was previously unrecognized

or untreated. Primary services are available at our

community-based UH Richmond Medical Center.

Minimally invasive and nonsurgical solutionsTreatment refractory disorders may also be helped by the most advanced neuro-stimulation techniques, including:

• Electroconvulsive Therapy (ECT): External electrical stimulation of the brain to induce controlled seizure activity to treat refractory depression

Conditions treated:• Mood and anxiety disorders

• Drug and alcohol addiction recovery

• Delirium, dementia and psychiatric disorders of aging

• Psychiatric sequellae of neurologic conditions

InnovationsThe Neuropsychiatry Center is nationally renowned for pioneering advanced protocols for treatment refractory disorders, or disorders that are resistant to traditional therapy.

Patients may have access to pharmacologic treatments currently under investigation through research protocols of UH Case Medical Center National Institute of Mental Health “Bipolar Disorder Across the Lifespan” Center, the first funded Bipolar Center of Excellence in the United States.

Current clinical trialsPatients in our programs benefit through access to novel antipsychotic medications, antidepressants and various mood stabilizers that are generally not available. Following is an abbreviated list of current trials:

• Patients diagnosed with major depression or bipolar disorder may benefit from participation in an ongoing research study being conducted within the Mood & Metabolic Clinic. We are currently enrolling participants in a National Institutes of Health (NIH)-sponsored research project to test whether the treatment of insulin resistance can reduce symptoms of depression. Patients with obesity or those who have not responded to traditional antidepressant medications are encouraged to participate.

• Longitudinal Assessment of Mania Symptoms (LAMS) – An epidemiological based study that assesses symptoms of mania every six months for a five-year period.

• Collaborative Lithium Trial (COLT) – A multiphase study designed to assess the safety and efficacy of Lithium in children and adolescents with Bipolar I disorder.

For more information on available clinical trials call 216-844-2865 or visit UHhospitals.org/neuro/clinicaltrials

Programs:• Addiction Recovery Services: The Neuropsychiatry Center

houses an addiction recovery program at the W.O. Walker Center. Here, patients can be treated on an intensive outpatient basis where they come to the center three to five days a week and return home in the evening. Treatment includes an innovative concept of a UH unique 12-Step Program for patients suffering from both a mental illness and an addiction problem.

• Connor Integrative Medicine Network: This program offers a unique approach to healing and well-being that blends evidence-based, holistic therapies like acupuncture, massage, yoga and Reiki with traditional medicine to promote optimal health of the mind, body and spirit.

• Neuro-geriatric Program: Provides comprehensive inpatient and outpatient assessment and treatment for older adults with psychiatric illness or adults with psychiatric illness and co-occurring medical or neurological illness.

• Discovery & Wellness Center for Children: Our mission is to compassionately conduct clinically meaningful research that will better the lives of children and adolescents suffering from psychiatric illnesses. Research-based treatment programs are currently available for children and adolescents who suffer from problems such as schizophrenia, bipolar disorder, adult and childhood ADHD and disruptive behavior disorders and depression. All of these programs are provided at NO cost to the family.

• Mood & Metabolic Clinic (MMC): Developed out of the recognition that depressive disorders frequently co-occur with illnesses affecting the body’s metabolism. This program delivers personalized outpatient care to patients with mood disorders and co-occurring “metabolic” illnesses such as obesity, prediabetes and the metabolic syndrome.

• Consultation Psychiatry/Psychosomatic Medicine: The Division of Psychiatry and Medicine is a newly formed addition to the University Hospitals Department of Psychiatry, and offers comprehensive psychiatric care for patients with significant co-occurring medical illnesses in both outpatient and inpatient settings. Our primary goal is to foster a multidisciplinary team approach and to recognize the importance of the mind-body connection in patient care. Current sections of the division include: Emergency Department-UH Case Medical Center, Transplant Service, Psycho-Oncology and Dermatology.

All National Institute of Mental Health (NIMH) funding for basic and clinical research is awarded to the School of Medicine at Case Western Reserve University.

Robert J. Ronis, MD, MPHOffice Phone: 216-844-3883Appointment Phone: 216-844-3883

Special Interests: Community Psychiatry, Adult Ambulatory, Psychopharmacology, Chemical Dependency, Psychotherapy, Addiction Psychiatry, Community Mental Health

Sees Patients at: W.O. Walker Center

Joseph A. Locala, MDOffice Phone: 216-844-2400Appointment Phone: 216-844-2400

Special Interests: Adult Psychiatry, Psychosomatic Psychiatry, Psychiatric Care of Medically Ill Patients, Transplant Psychiatry, Mood Disorders in the Medically Ill, Anxiety Disorders in the Medically Ill

Sees Patients at: UH Case Medical Center, W.O. Walker Center

Francoise Adan, MDOffice Phone: 216-285-4070Appointment Phone: 216-285-4070

Special Interests: Integrative Psychiatry, Mood and Anxiety Disorders, Pharmacotherapy and Psychotherapy

Sees Patients at: UH Ahuja Medical Center

Felipe Amunategui, PhDOffice Phone: 216-844-3881Appointment Phone: 1-866-UH4-CARE

Special Interests: Cognitive Behavior Therapy, Adolescent Co-Morbid Disorders, Treatment Refractory Disorders, Child-Onset Mood and Anxiety Disorders, Disruptive Behavior Disorders, Parent-Child Relationship Problems, Psychotherapy, Psychotherapy Process Research, Graduate Education/Training, School/Community Consultation, Program Design/Evaluation, Self-Producing Systems

Sees Patients at: W.O. Walker Center

Christopher Bedosky, PhDOffice Phone: 216-844-8550Appointment Phone: 1-866-UH4-CARE

Special Interests: Child Adolescent and Adult Psychotherapy and Psychological Testing, Disruptive Behavioral Disorders

Sees Patients at: W.O. Walker Center

Philipp L. Dines, MD, PhDOffice Phone: 216-844-2400Appointment Phone: 216-844-2400

Special Interests: Adult Psychiatry, ECT, Geropsychiatry, Forensic Psychiatry, Geriatric Mood Disorders, Geriatric Psychotic Disorders, Dementia, Brain Injury, Mental Retardation, Psychiatric Issues in Neurological and Medical Primary Illnesses

Sees Patients at: UH Foley ElderHealth Center, W.O. Walker Center, UH Westlake Health Center

Keming Gao, MD, PhDOffice Phone: 216-844-2400Appointment Phone: 216-844-2400

Special Interests: Adult Psychiatry, Anxiety Disorders, Bipolar Disorders Research, ECT, Moods, Phenomenology and Psychopharmacotherapy

Sees Patients at: W.O. Walker Center

John Hertzer, MDOffice Phone: 216-844-3881Appointment Phone: 216-844-3881

Special Interests: Child Psychiatry, Adolescent Psychiatry, Psychopharmacology for Kids

Sees Patients at: W.O. Walker Center

Jeff Janata, PhDOffice Phone: 216-844-8550Appointment Phone: 216-844-8550

Special Interests: Autonomic Disorders, Behavior Therapy, Behavioral Medicine, Cognitive Behavioral Psychotherapy, Health Psychiatry, Health Psychology, Pain Management

Sees Patients at: UH MacDonald Women’s Hospital,W.O. Walker Center

Irina Korobkova, MDOffice Phone: 216-844-8726Appointment Phone: 216-844-2400

Special Interests: Dementia, ECT, Geriatric Psychiatry, Geropsychiatry

Sees Patients at: W.O. Walker Center,UH Richmond Medical Center

Jeanne Lackamp, MDOffice Phone: 216-844-2400Appointment Phone: 216-844-2400

Special Interests: Adult Psychiatry, Consultation, Medical Education

Sees Patients at: UH Case Medical Center, W.O. Walker Center

Zinaida Lebedeva, MDOffice Phone: 440-285-6588Appointment Phone: 216-844-2400

Special Interests: Adult Psychiatry, Geriatric Psychiatry

Sees Patients at: UH Case Medical Center, UH Geauga Medical Center

NEUROPSYCHIATRY CENTER

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NEUROPSYCHIATRY CENTER

Jennifer Levin, PhDOffice Phone: 216-844-2400Appointment Phone: 1-866-UH4-CARE

Special Interests: Cognitive Behavioral Therapy for the Treatment of Anxiety Disorders, Depression, Panic Disorder, OCD, Social Phobia, Generalized Anxiety Disorder, Behavioral Medicine (including management of chronic pain and chronic disease), Health Psychology

Sees Patients at: W.O. Walker Center

Molly McVoy, MDOffice Phone: 216-844-3881Appointment Phone: 1-866-UH4-CARE

Special Interests: Pediatric Mood Disorders, ADHD, Trauma-related Psychotherapy, Pediatric Anxiety Disorders, Psychopharmacology

Sees Patients at: W.O. Walker Center

Susan Padrino, MDOffice Phone: 216-844-3400Appointment Phone: 216-844-3400

Special Interests: Adult Psychiatry, Community Psychiatry, Internal Medicine, Resident Education, Medical Student Education, Physical Diagnosis, Direct Observation, Family Therapy, Residency Education

Sees Patients at: UH Case Medical Center, UH Seidman Cancer Center

Stefani Parrisbalogun, MDOffice Phone: 216-983-5650Appointment Phone: 216-983-5650

Special Interests: Adult Psychiatry, Psychiatric Care of Medically Ill Patients, Psychosomatic Medicine, Emergency Psychiatry, HIV/AIDS Psychiatry, Bariatric Psychiatry

Sees Patients at: W.O. Walker Center, UH Seidman Cancer Center

Amir Poreh, PhDOffice Phone: 216-983-3126Appointment Phone: 1-866-UH4-CARE

Special Interests: Psychology, Neuropsychological Assessment

Sees Patients at: W.O. Walker Center

Stephen Ruedrich, MDOffice Phone: 216-983-3088Appointment Phone: 216-983-3088

Special Interests: Intellectual and Developmental Disabilities

Sees Patients at: W.O. Walker Center

Martha Sajatovic, MDOffice Phone: 216-844-2400Appointment Phone: 216-844-2400

Special Interests: Adult Psychiatry, Geropsychiatry, Geriatric Psychiatry, Health Services, Bipolar Disorder

Sees Patients at: W.O. Walker Center

Rebecca R. Schlachet, DOOffice Phone: 216-844-2400Appointment Phone: 216-844-2400

Special Interests: Adult Psychiatry, Geriatric Psychiatry

Sees Patients at: W.O. Walker Center

Binit Shah, MDOffice Phone: 216-844-3771Appointment Phone: 216-844-3771

Special Interests: Psycho-Oncology, Chronic Pain, Pain Rehabilitation

Sees Patients at: UH Case Medical Center, UH Seidman Cancer Center, W.O. Walker Center

Karen Tien, PhDOffice Phone: 216-844-6015Appointment Phone: 216-844-6015

Special Interests: Child & Adolescent Psychology, Child Chronic Illness & Injury, Cognitive Behavioral Therapy, Parenting, Pediatric Injury, Psychological Adjustment Problems, Health Promotion, Cognitive-Behavioral Therapy

Sees Patients at: W.O. Walker Center

Solomon Zaraa, DOOffice Phone: 216-983-3718Appointment Phone: 216-983-3718

Special Interests: Child Psychiatry, Bipolar Disorder, ADHD, Depression in Children and Adolescents

Sees Patients at: UH Case Medical Center, UH Seidman Cancer Center, W.O. Walker Center

UH Neurological Institute’s Neuroscience Nursing Practice

Center is dedicated to the development and implementation

of best practices in neuroscience nursing. Our mission is to

improve patients’ long-term outcomes by providing care

according to the most advanced protocols based on the

latest research findings; offering highly personalized care;

and maximizing efficiencies during every stage of treatment.

These strategies are implemented throughout the

continuum of patient care from first diagnosis,

through treatment and follow-up.

Clinical practice is based on three core principals:

• Evidence-based nursing practice – bridges the gap between nursing research and clinical practice

• Patient-centered care – places responsibility for important aspects of self-care and monitoring in the patients’ hands by providing tools and support

• Relationship-based nursing – maintains a standard of excellence by relying on the principles of relationship-based nursing

Treatment from UH neuroscience nurses provides multidisciplinary services including rehabilitation, pharmacy, social work, nutrition and medical services. Patient-centered care also takes into consideration individual circumstances including lifestyle, family situations, cultural traditions, religious beliefs and other factors during care planning and implementation. Patients are able to contribute to important aspects of their care and healing, and are prepared with the tools and support needed to carry out this responsibility. In this way, patient-centered care can reduce unneeded and unwanted services as well as improve outcomes.

InnovationsThe Neuroscience Nursing Practice Center aims to bridge the gap between nursing research and clinical practice by creating mechanisms to facilitate the translation of information from evidence-based research to practice. In this way, we ensure critical, succinct, reasonable evaluation and application of research findings as they relate to point-of-care delivery.

• Preoperative Bundle for Neurosurgery: Nursing worked in collaboration with Neurosurgery and Infection Control to develop a presurgical regimen which is now used for the outpatient preoperative neurosurgery patients and also for inpatient neurosurgery patients going for surgery. This process includes screening patients for MRSA/MSSA and prophylactically treating with mupirocin as well as bathing the patient with an alcohol-based scrub. With the implementation of the presurgical bundle, the rate of postoperative infections has shown a decrease.

• External Ventricular Drain: Nurses in the Neuroscience Intensive Care Unit (NSU) developed a guideline to standardize care of external ventricular drains (EVD). The standardized guideline provides instruction for drain placement which includes giving prophylactic antibiotics prior to drain placement including nursing management of the drain as well as CSF sampling techniques. Data is being collected to evaluate the positive effect this guideline has on improved EVD management.

Current clinical trialsTo bridge the gap between nursing research and clinical practice, the center aims to put evidence-based research into practice. This ensures high-quality care backed by scientific nursing services.

The Neuroscience Nursing Practice Center, in collaboration with the Case Western Reserve University Frances Payne Bolton School of Nursing, is working on a quality improvement research project to standardize nursing care of external ventricular drainage systems to decrease infection rates.

NEUROSCIENCE NURSING PRACTICE CENTER

Erin Supan, RNDirector, Neuroscience Nursing Practice Center Office Phone: 216-844-2413

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PARKINSON’S & MOVEMENT DISORDERS CENTER

UH Neurological Institute’s Parkinson’s & Movement

Disorders Center is comprised of a multidisciplinary

team of specialists that offer pharmaceutical therapy

and surgical management to treat the complex

implications of movement disorders.

Surgical solutions:• Functional and Restorative Neurosurgery: State-of-the-art Deep

Brain Stimulation (DBS) surgery, as well as comprehensive preoperative and postoperative care for patients undergoing DBS. Careful, fine-tuned programming of DBS stimulators, balanced with medical management, is provided on an ongoing basis.

• Deep Brain Stimulation (DBS) Program: Manages tremors, movement and walking problems via surgical implantation of electrodes in the brain and pulse generators in the upper chest just beneath the collarbones.

Minimally invasive and nonsurgical solutions:• Botulinum Toxin Therapy: Used to treat movement disorders,

spasticity, drooling, migraine and other indications

• Intrathecal Baclofen Therapy (IBT): Effective in treating chronic pain and spasticity

Conditions treated:• Parkinson’s disease

• Essential tremor

• Dystonia

• Huntington’s disease

Innovations:• First in North America to perform DBS of the thalamus to treat

symptoms of Tourette syndrome successfully.

• The first group worldwide to complete a prospective randomized double blinded trial of thalamic DBS for Tourette syndrome in a pilot clinical trial of five patients.

• Greatest experience in Ohio with botulinum toxin injections, and uses the procedure for the broadest range of neurological indications.

Programs:• Huntington’s Disease Interdisciplinary Clinic: Offers neurology,

psychiatry, social work and genetics evaluation to patients and their families. Prescreening examinations to patients’ adult family members are also available.

• Pediatric Neurosurgery: Our expert neurosurgeons are skilled in the latest approaches and use the latest technologies to provide customized surgical solutions to pediatric patients with a wide variety of neurological conditions.

Current clinical studies:• Establishment of a CTSC Parkinson’s Disease Phenotypic and

Genotypic Registry. The purpose of this research study is to establish a registry of people with Parkinson’s disease (PD) to examine the effects of genes on PD. Investigators will compare disease features in people with certain gene mutations associated with PD but without those mutations, attempting to identify any distinctive characteristics. Investigators will also try to determine how the mutations contribute to the damage done to nerve cells in PD.

• BrainGate2: Feasibility Study of an Intracortical Neural Interface System for Persons with Tetraplegia. Obtain preliminary device safety information and demonstrate proof of principle (feasibility of efficacy) of the ability of people with tetraplegia to control a computer cursor and other assistive devices with their thoughts. Prospective, open-label, feasibility study. Primary Endpoint: Safety: Sensor successfully implanted, not explanted for safety reasons during the one-year post-implant evaluation, and there are no device-related Serious Adverse Events which result in death or permanently increased disability during the one-year post-implant evaluation period.

• AM IMPAKT Study. A Phase 4, open-label, efficacy and safety study of APOKYN® for rapid and reliable improvement of motor symptoms in Parkinson’s disease subjects with delayed onset of levodopa (L dopa) action. This is a multicenter, multiple-treatment, open-label design, outpatient study to assess the effect of APOKYN treatment in rapid and reliable improvement of motor symptoms in Parkinson’s disease subjects suffering from delayed or unreliable onset of (L dopa) action.

• Functional Magnetic Resonance Imaging (fMRI) Investigations of the Pathophysiology and effects of Deep Brain Stimulation in Dystonia: This NIH-sponsored study aims to reveal changes in the integration of brain sensory and motor systems in patients with dystonia using advanced imaging techniques and to also use these techniques in patients undergoing Deep Brain Stimulation to understand how the integration of these systems change as dystonia improves. This information will lead to understanding into both the pathophysiology of dystonia, and the mechanism by which DBS produced its improvement. This may furthermore be used to advance the treatment of dystonia by improving the location or method by which DBS is delivered and through the development of new therapeutic approaches.

• Functional Magnetic Resonance Imaging (fMRI) Investigations of the Pathophysiology of Parkinson’s disease: This pilot study aims to understand brain network changes involved in changes in the handling and perception of proprioceptive information in patients with Parkinson’s disease. Information gained from this study may be used to develop functional markers for progression of Parkinson’s disease and may reveal the neural circuitry involved in the alterations of perception of scale in patients with Parkinson’s disease.

All National Institutes of Health funding for basic and clinical research is awarded to the School of Medicine at Case Western Reserve University.

Benjamin L. Walter, MDOffice Phone: 216-844-8285Appointment Phone: 216-844-2724

Special Interests: Dystonia, Tremors, Movement Disorders, Functional Magnetic Resonance Imaging (MRI), Mechanisms of Effect of DBS, Deep Brain Stimulation, Parkinson’s Disease

Sees Patients at: UH Case Medical Center, UH University Suburban Health Center, UH Medina Health Center, UH Westlake Health Center

Steven A. Gunzler, MDOffice Phone: 216-844-8685Appointment Phone: 216-844-2724

Special Interests: Ataxia, Neurology, Dystonia, Memory and Aging, Botulinum Toxin Injections, Movement Disorders, Dementia, Parkinson’s Disease, Huntington’s Disease, Tremors

Sees Patients at: UH Ahuja Medical Center, UH University Suburban Health Center, UH Foley ElderHealth Center

Camilla Kilbane, MDOffice Phone: 216-844-3192Appointment Phone: 216-844-2724

Special Interests: Movement Disorders, Neurology, Deep Brain Stimulation, Dystonia, Essential Tremor, Neurophysiology, Parkinson’s Disease, Functional Movement Disorders, Genetics, Huntington’s Disease, Tourette’s Syndrome, Tremors, Botulinum Toxin Injections, Myoclonus, Chorea, Tics

Sees Patients at: UH Case Medical Center,UH University Suburban Health Center, UH Westlake Health Center

Joseph A. Locala, MDOffice Phone: 216-844-2400Appointment Phone: 216-844-2400

Special Interests: Adult Psychiatry, Psychosomatic Psychiatry, Psychiatric Care of Medically Ill Patients, Transplant Psychiatry, Mood Disorders in the Medically Ill, Anxiety Disorders in the Medically Ill

Sees Patients at: UH Case Medical Center, UH Seidman Cancer Center, W.O. Walker Center

Jonathan Miller, MDOffice Phone: 216-844-3470Appointment Phone: 216-844-2724

Special Interest: Movement Disorders Surgery

Sees Patients at: UH Case Medical Center

Amy Stralka-Larson, NPOffice Phone: 216-844-8285Appointment Phone: 216-844-2724

Special Interest: Movement Disorders

Sees Patients at: UH Case Medical Center, UH Ahuja Medical Center

Ellen Walter, NPOffice Phone: 216-291-2021Appointment Phone: 216-844-2724

Special Interest: Movement

Sees Patients at: UH Case Medical Center

PARKINSON’S & MOVEMENT DISORDERS CENTER

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UHhospitals.org/Neuro • UH Neurological Institute | 4342 | University Hospitals • 216-844-2724

UH Neurological Institute’s Spinal Neurosurgery Center offers

the most innovative and sophisticated surgical techniques

along with proven conventional methods to treat the full

range of spinal disorders. Our physicians are nationally

recognized for their expertise in minimally invasive spinal

surgery techniques and have taught numerous courses on

the subject around the country. Our emphasis is on the total

care of the patient, viewing their spinal problem as it affects

their whole person, not just the spine.

Surgical solutions:• Spinal decompression (laminectomy, discectomy)

• Minimally invasive surgery

• Microsurgery of the spinal cord

• Microvascular surgery

• Spinal implants

• Numerous fusion techniques

• Dynamic spinal stabilization

• Spinal cord and cauda equina

• Revision spine surgery

• Deformity correction

• Image guided surgery

Minimally invasive and nonsurgical solutions:• CyberKnife® Radiosurgery for spinal tumors

• Kyphoplasty

• X-stop device

Conditions treatedThe Spinal Neurosurgery Center fosters an interdisciplinary collaboration with pain medicine interventionalists, orthopaedic surgeons and physical therapists to develop treatment plans according to each patient’s individual needs. Conditions treated include:• Arthritis

• Degenerative disorders/aging of the spine

• Fractures

• Herniated discs

• Infections of the spine

• Injury, trauma to back, neck, spine or spinal cord

• Malignant and benign spinal tumors

• Chronic spinal pain

• Spinal cord compression

• Spinal deformities (scoliosis, kyphosis)

• Spinal stenosis

Special equipment:• CyberKnife® Radiosurgery

• Image guidance in spinal surgery for trauma (Iso-C)

• BrainLAB

Program:• Pediatric Neurosurgery: Our expert neurosurgeons are skilled in

the latest approaches and use the latest technologies to provide customized surgical solutions to pediatric patients with a wide variety of neurological conditions.

Current clinical trialsThe Spinal Neurosurgery Center is currently recruiting for the following:

• DuraSeal. This multicenter, nonrandomized, post-approval study with a prospective treatment arm and a retrospective control arm will further evaluate the rate of post-operative CSF leaks in subjects who undergo a spinal procedure and receive DuraSeal Spine Sealant for treatment of either an intentional or incidental opening of the dura as compared to control patients who receive other products and/or treatments to close the dura.

• Prospective, Randomized, Multicenter Clinical Study Comparing Axial Lumbar Interbody Fusion (AxiaLIF®) and Transforaminal Lumbar Interbody Fusion (TLIF) Spinal Procedures. The primary objective of the study is to demonstrate noninferiority between the axial lumbar interbody fusion procedure (AxiaLIF) and the transforaminal lumbar interbody fusion procedure (TLIF) by meeting the following primary and secondary study endpoints: Primary Endpoint – Efficacy: Fusion of the targeted vertebral bodies (L4-L5-S1 or L5-S1) will be assessed individually at 24 months as determined by Central Radiographic Reviewer’s (orthopaedic surgeon) interpretation of high resolution computed tomography (CT) Scan; Secondary Endpoints – Safety: Incidence of major device-related adverse events by 24 months, defined as those requiring revision surgery or a secondary operation, or events resulting in permanent disability or death; Clinical Effectiveness: A 20 percent decrease in back pain compared to baseline at 24 months as measured by the Visual Analog Scale (VAS) score; Clinical Effectiveness: A 20 percent decrease in disability at 24 months compared to baseline as measured by the Oswestry Disability Index (ODI). Additional evaluations will also be collected to measure specific health outcomes throughout the study, including but not limited to, operative measures, time to return to work and activity post-surgery and quality of life relative to baseline as measured by the SF-36® Health Survey.

SPINAL NEUROSURGERY CENTER

Mirza Baig, MDOffice Phone: 216-286-6486Appointment Phone: 1-866-UH4-CARE

Special Interests: Physical Medicine, Rehabilitation

Sees Patients at: UH Case Medical Center, UH Rehabilitation Hospital

Nicholas C. Bambakidis, MDOffice Phone: 216-844-8758Appointment Phone: 216-844-2724

Special Interests: Spine Surgery, Spinal Cord Tumors

Sees Patients at: UH Case Medical Center, UH Ahuja Medical Center

Stephen Fulop, MDOffice Phone: 440-816-2860Appointment Phone: 440-816-2860

Special Interests: Minimally Invasive Spinal Surgery, Navigated Spinal Surgery, Cervical Degenerative Disease

Sees Patients at: Southwest General Health Center

Rishi Goel, MDOffice Phone: 440-250-9133Appointment Phone: 440-250-9133

Special Interests: General Neurosurgery, Spine Surgery, Spinal Cord Tumors

Sees Patients at: Southwest General Health Center, St. John Medical Center

Seth Alan Hoffer, MDOffice Phone: 216-844-5744Appointment Phone: 216-844-2724

Special Interests: Spine Surgery, Spinal Cord Tumors

Sees Patients at: UH Case Medical Center, UH Richmond Medical Center, UH Bedford Medical Center

Roseanna Lechner, MDOffice Phone: 216-285-5131Appointment Phone: 216-844-2724

Special Interests: Spine Surgery, Degenerative and Developmental Disorders, Tumors, Trauma, Minimally Invasive Spine Surgery

Sees Patients at: UH Ahuja Medical Center, UH Geauga Medical Center, UH Twinsburg Health Center

Jonathan Miller, MDOffice Phone: 216-844-3470Appointment Phone: 216-844-2724

Special Interests: Pain Neurosurgery, Stereotatic & Functional Neurosurgery, Gamma Knife® Stereotactic Radiosurgery, Spine Surgery, Spinal Cord Tumors

Sees Patients at: UH Case Medical Center

Richard Rhiew, MDOffice Phone: 440-816-2860Appointment Phone: 440-816-2860

Special Interests: General Neurosurgery, Physiology, Functional Neurosurgery, Spine Surgery

Sees Patients at: Southwest General Health Center

Bhupinder Sawhny, MDOffice Phone: 440-891-8880Appointment Phone: 440-891-8880

Special Interest: Neurosurgery

Sees Patients at: Southwest General Health Center

Warren R. Selman, MDOffice Phone: 216-844-5745Appointment Phone: 216-844-2724

Special Interests: Spine Surgery, Spinal Cord Tumors

Sees Patients at: UH Case Medical Center

Jennifer Sweet, MDOffice Phone: 216-983-3334Appointment Phone: 216-844-2724

Special Interest: Epilepsy Surgery

Sees Patients at: UH Case Medical Center

SPINAL NEUROSURGERY CENTER

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UHhospitals.org/Neuro • UH Neurological Institute | 4544 | University Hospitals • 216-844-2724

TRAUMATIC BRAIN INJURY CENTER

Traumatic brain injury (TBI) is a complex medical condition

requiring specialized care to ensure the best patient

outcome. The wide spectrum of injuries encompasses

everything from mild concussion to life-threatening swelling

and bleeding. Despite this broad range of injury severity,

even the mildest injuries can have long-lasting effects.

The Traumatic Brain Injury Center within UH Neurological

Institute is a comprehensive, multidisciplinary, longitudinal

program that addresses all aspects of TBI. From the

emergency room to the intensive care unit to rehabilitation,

our experts deliver leading-edge care so that our patients can

regain the physical and cognitive functions that allow them

to recover from brain trauma.

Conditions treated:• Traumatic brain injury

• Mild traumatic brain injury

• Concussion

• Cerebral contusion

• Post-traumatic intracranial hypertension

• Post-traumatic cerebral herniation

• Skull fracture

• Epidural hematoma

• Subdural hematoma

• Penetrating head injury

• Post-traumatic CSF leak (otorrhea, rhinorrhea)

Special equipmentWe review minute-to-minute progress with the most advanced monitoring equipment in the world, including:

• Brain tissue oxygenation monitoring

• Cerebral blood flow monitoring

• Continuous video EEG monitoring

• CT angiography and CT perfusion studies

• Intracranial pressure monitoring

• MRI perfusion – diffusion imaging

• Positron emission tomography (PET)

• Transcranial doppler (TCD) ultrasonography

Inpatient Care of Acute TBIComprehensive inpatient care of the brain-injured patient requires the coordinated efforts of many specialists. At University Hospitals, we have put together a multidisciplinary group of physicians, nurses and therapists to address the needs of our patients and their families.

Our Beacon Award-winning Reinberger Neurosciences Intensive Care Unit (NSU) is the cornerstone of the care we deliver. This dedicated 14-bed ICU operates 24 hours a day under the supervision of neurosurgeons and critical care intensivists. Staffed by intensive care nurses who have completed specialized training in the care of patients with neurologic injuries, the NSU offers patients the most up-to-date technologies in brain physiology monitoring and treatment.

Focusing on early detection and rapid intervention to minimize and reverse the effects of brain trauma, our neurosurgeons are dedicated to giving patients their best chance of maintaining and recovering neurologic function.

Although brain and spinal injuries are the primary diagnoses of patients in the NSU, every organ system may be at risk. Fellowship-trained neurointensivists are on hand to treat the medical problems that may affect the heart, lungs and other organs.

Seth Alan Hoffer, MDOffice Phone: 216-844-5744Appointment Phone: 216-844-2724

Special Interests: Neurocritical Care, Spine Surgery, Traumatic Brain Injury

Sees Patients at: UH Case Medical Center, UH Richmond Medical Center, UH Bedford Medical Center

Mirza Baig, MDOffice Phone: 216-286-6486Appointment Phone: 1-866-UH4-CARE

Special Interests: Physical Medicine, Rehabilitation

Sees Patients at: UH Case Medical Center, UH Rehabilitation Hospital

Christopher Bailey, PhDOffice Phone: 216-844-3422Appointment Phone: 216-844-2724

Special Interests: Adult/Geriatric Neuropsychology, Alzheimer’s Disease, Attention Deficit/Hyperactivity Disorder (ADD/ADHD), Concussion, Dementia, Disability/Legal, Deep Brain Stimulation Surgery, Epilepsy and Epilepsy Surgery, Forensic Neuropsychology, Hydrocephalus, Memory Loss, Mild Cognitive Impairment, Neuropsychological Independent Medical Exam, Traumatic Brain Injury (TBI)

Sees Patients at: UH Case Medical Center, UH Ahuja Medical Center

Nicholas C. Bambakidis, MDOffice Phone: 216-844-8758Appointment Phone: 216-844-2724

Special Interests: Spinal Cord Injuries, Traumatic Brain Injury, Skull Base Surgery, Cerebrovascular Surgery

Sees Patients at: UH Case Medical Center, UH Ahuja Medical Center

Michael DeGeorgia, MDOffice Phone: 216-844-1552Appointment Phone: 216-844-2724

Special Interests: Critical Care Bioinformatics, Hemorrhagic Stroke, Hypothermia, ICU Monitoring, Ischemic Stroke, Neurocritical Care

Sees Patients at: UH Case Medical Center

Ciro Estabenez, MDOffice Phone: 216-844-3192

Appointment Phone: 216-844-2724

Special Interests: General Neurology, Neuromuscular

Disorders, Neurocritical Care, Stroke

Sees Patients at: UH Case Medical Center

TRAUMATIC BRAIN INJURY CENTER

Recognition and Rehabilitation After TBIPhysical and cognitive rehabilitation are essential to restore function following traumatic brain injury. Patients hospitalized at UH Case Medical Center may continue their comprehensive care at UH’s neurorehabilitation unit. This facility specializes in treating patients with brain injuries. With intensive therapies, patients are able to maximize their physical and mental abilities with the goal of returning to preinjury level of functioning.

While the brain is not able to regenerate itself as other organs can, the brain can often form new pathways following injury that facilitate recovery. Therapies overseen by neuropsychologists and rehabilitation physicians allow patients to retrain their minds and bodies.

Mild traumatic brain injuries such as concussion can go undetected – though their effects can have a profound impact upon the ability to perform at work or school, social functioning, and the prevalence of depression and anxiety. Our neuropsychologists are recognized for their advances in the detection and treatment of mild TBI, which is essential to patient recovery.

Our sports concussion team offers preseason baseline assessments to teams throughout Northeast Ohio to ensure that no student athletes return to their sport before they are ready. This combination of questionnaires and computerized tests measures a number of basic cognitive functions and is given before the season starts.

Future Directions in TBI Treatment Working in conjunction with Case Western Reserve University School of Medicine, University Hospitals’ basic science and translational research program for TBI examines the biology of brain injuries and is focused on developing therapies to protect and restore the brain. Collaborating with the National Institutes of Health, the Department of Defense and investigators around the globe, our team is studying the mechanisms of cell injury and death after brain trauma, the effects of TBI on cognition and behavior, and compounds that can be used to treat the injured brain.

While laboratory research is essential to medical progress, translating those discoveries into human treatments is a hallmark of our center as direct brain stimulation is used to help patients recover from brain injury. Stimulation by electrode implantation can retrain the brain to regain function lost by trauma.

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Philip Fastenau, PhDOffice Phone: 216-844-3422Appointment Phone: 216-844-2724

Special Interests: Alzheimer’s Disease, Attention Deficit/Hyperactivity Disorder (ADD/ADHD), Concussion, Deep Brain Stimulation Surgery, Dementia, Epilepsy and Epilepsy Surgery, Hydrocephalus, Learning Disability (LD), Memory Loss, Mild Cognitive Impairment, Neuropsychological Test Development, Pediatric/Adult/Geriatric Neuropsychology, Traumatic Brain Injury (TBI)

Sees Patients at: UH Case Medical Center,UH Westlake Health Center

Cynthia Griggins, PhDOffice Phone: 216-844-1852Appointment Phone: 216-844-2724

Special Interests: ADHD and Learning Disabilities in Adults, Chronic Medical Conditions, Clinical Ethics, Cognitive Rehabilitation, Counseling and Therapy for Neurological Disorders, Dementia, Head Injury, Higher Cortical Functions, Language Mapping, Neuroethics, Neuropsychological Assessment of Adults and Adolescents, Stroke

Sees Patients at: UH Case Medical Center

Alan J. Lerner, MDOffice Phone: 216-464-6412Appointment Phone: 216-464-6445

Special Interests: Alzheimer’s Disease, Dementia, Behavioral Neurology, General Neurology, Higher Cortical Functions, Adult Attention Deficit Disorder (adult ADD/ADHD)

Sees Patients at: UH Ahuja Medical Center, UH Foley ElderHealth Center

James Mack, PhDOffice Phone: 216-844-3Special Interest: NeuropsychiatrySees Patients at: UH Rehabilitation Hospital

Jonathan Miller, MDOffice Phone: 216-844-3470Appointment Phone: 216-844-2724

Special Interests: Pain Neurosurgery, Movement Disorders Surgery, Facial Pain, Peripheral Nerve Surgery, Stereotatic and Functional Neurosurgery, Epilepsy Surgery, Gamma Knife® Stereotactic Radiosurgery

Sees Patients at: UH Case Medical Center

Warren R. Selman, MDOffice Phone: 216-844-5745Appointment Phone: 216-844-2724

Special Interests: Cerebrovascular Surgery, Spinal Cord Injuries, Traumatic Brain Injury, Skull Base Surgery

Sees Patients at: UH Case Medical Center

Crystal Tomei, MD, MPHOffice Phone: 216-844-5741Appointment Phone: 216-844-7337

Special Interests: Hydrocephalus, Pediatric Brain Tumors, Congenital Spinal Disorders and Spina Bifida, Tethered Cords, Craniosynostosis, Spasticity, Spinal Deformities, Pediatric Traumatic Brain Injury, Pediatric Spinal Injury

Sees Patients at: UH Rainbow Babies & Children’s Hospital

Todd Zeiger, MDOffice Phone: 330-239-4455Appointment Phone: 330-239-4455

Special Interests: Chronic Disease Management, FAA Exams, Sports Injuries

Sees patients at: Sharon Family Physicians

TRAUMATIC BRAIN INJURY CENTER

Name Specialty Page Office Phone

Adan, Francoise, MD Neuropsychiatry 37 216-844-2400

Amina, Shahram, MD Epilepsy 24 216-844-3675

Amunategui, Felipe, PhD Neuropsychiatry 37 216-844-3881

Andrefsky, John, MD Community Neurology 16 440-743-8120

Appleby, Brian, MD Brain Health & Memory 9 216-464-6445

Arafah, Baha, MD Brain Tumor & Neuro-Oncology 13 216-844-3142

Ashraf, Fareeha, MD Epilepsy 24 216-844-3192

Baig, Mirza, MD Functional & Restorative Neurosurgery, Spinal Neurosurgery, Traumatic Brain Injury 27, 43, 45 216-286-6486

Bailey, Christopher, PhD Brain Health & Memory, Traumatic Brain Injury 9, 45 216-844-3422

Bambakidis, Nicholas C., MD Brain Tumor & Neuro-Oncology, Comprehensive Stroke, Spinal Neurosurgery, Traumatic Brain Injury 13, 20, 43, 45 216-844-8758

Bardenstein, David, MD Brain Tumor & Neuro-Oncology 13 216-844-8686

Bedosky, Christopher, PhD Neuropsychiatry 37 216-844-8550

Buczek, Marek A., MD, PhD Community Neurology, Comprehensive Stroke, Neuromuscular 16, 20, 34 440-250-5303

Coffey, Michael, MD Brain Tumor & Neuro-Oncology 13 216-844-3061

Cohen, Mark L., MD Brain Tumor & Neuro-Oncology 13 216-844-8928

de Blank, Peter, MD, MS Brain Tumor & Neuro-Oncology 13 216-844-3345

Debrosse, Suzanne, MD Brain Health & Memory 9 216-844-3936

DeGeorgia, Michael A., MD Leadership, Comprehensive Stroke, Music & Medicine, Neurocritical Care, Traumatic Brain Injury 4, 20, 28, 31, 45 216-844-1552

Devereaux, Michael W., MD Community Neurology, Epilepsy 16, 24 216-844-3591

Dines, Philipp L., MD, PhD Neuropsychiatry 37 216-844-2400

Dupont, Stefan, MD, PhD Community Neurology, Comprehensive Stroke 16, 20 216-285-5041

Dyko, Brian, NP Neuromuscular 35 216-844-3495

Eccher, Matthew, MD, MSPH Epilepsy 24 216-844-1764

Elmo, Mary Jo, CNP Neuromuscular 35 216-844-8594

INDEX

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INDEX

Name Specialty Page Office Phone

Estabenez, Ciro, MD Comprehensive Stroke, Neurocritical Care, Traumatic Brain Injury 20, 31, 45 216-844-3192

Fastenau, Philip, PhD Brain Health & Memory, Traumatic Brain Injury 9, 46 216-844-3422

Fulop , Stephen, MD Spinal Neurosurgery 43 440-816-2860

Furlan, Anthony J., MD Leadership, Comprehensive Stroke 4, 20 216-844-3193

Gao, Keming, MD, PhD Neuropsychiatry 37 216-844-2400

Gerson, Stanton, MD Brain Tumor & Neuro-Oncology 13 216-844-8562

Gibbons, Joseph, MD Brain Tumor & Neuro-Oncology 13 216-844-4735

Goel, Rishi, MD Spinal Neurosurgery 43 440-250-9133

Gold, Deborah, MD Brain Tumor & Neuro-Oncology 13 216-844-3691

Griggins, Cynthia, PhD Brain Health & Memory, Traumatic Brain Injury 9, 46 216-844-1852

Grossman, Gerald E., MD Neuromuscular 35 216-844-8925

Gunzler, Steven A., MD Brain Health & Memory, Parkinson’s & Movement Disorders 9, 41 216-844-8685

Hertzer, John, MD Neuropsychiatry 37 216-844-3272

Hoffer, Seth Alan, MD Leadership, Brain Tumor & Neuro-Oncology, Neurocritical Care, Spinal Neurosurgery, Traumatic Brain Injury 4, 13, 31, 43, 45 216-844-5744

Janata, Jeff, PhD Neuromuscular, Neuropsychiatry 35, 37 216-844-8550

Kahl, Rebecca Leadership 4 216-844-8598

Katirji, Bashar, MD Leadership, Functional & Restorative Neurosurgery, Neuromuscular 4, 27, 34 216-844-4854

Kilbane, Camilla, MD Parkinson’s & Movement Disorders 41 216-844-3192

Koon, Henry B., MD Brain Tumor & Neuro-Oncology 14 216-844-0120

Korobkova, Irina, MD Neuropsychiatry 37 216-844-8726

Kumar, Suresh, MD Community Neurology 17 440-816-6794

Lackamp, Jeanne, MD Neuropsychiatry 37 216-844-2400

Lang, Pamela, CNS Epilepsy 24 216-844-5383

Lanzieri, Charles, MD Brain Tumor & Neuro-Oncology 14 216-844-5721

Name Specialty Page Office Phone

Lass, Jonathan, MD Music & Medicine 28 216-844-8590

Lebedeva, Zinaida, MD Neuropsychiatry 37 440-285-6588

Lechner, Roseanna, MD Spinal Neurosurgery 43 216-285-5131

Lerner, Alan J., MD Leadership, Brain Health & Memory, Music & Medicine, Traumatic Brain Injury 4, 9, 28, 46 216-464-6412

Levin, Jennifer, PhD Neuropsychiatry 38 216-844-2400

Lhatoo, Samden, MD Leadership, Epilepsy, Functional & Restorative Neurosurgery 4, 24, 27 216-844-5855

Lo, Simon, MD Brain Tumor & Neuro-Oncology 14 216-844-3103

Locala, Joseph A., MD Leadership, Brain Tumor & Neuro-Oncology, Epilepsy, Neuromuscular, Neuropsychiatry, Parkinson’s & Movement Disorders

4, 14, 24, 35, 37, 41 216-844-2400

Lüders, Hans O., MD, PhD Epilepsy, Music & Medicine 24, 28 216-844-3650

Lyons, Janice A., MD Brain Tumor & Neuro-Oncology 14 216-844-2536

Machtay, Mitchell, MD Brain Tumor & Neuro-Oncology 14 216-844-2530

Mack, James, PhD Brain Health & Memory, Traumatic Brain Injury 9, 46 216-844-3188

Maronian, Nichole, MD Music & Medicine 29 216-983-3455

McVoy, Molly, MD Neuropsychiatry 38 216-844-3881

Megerian, Cliff A., MD Brain Tumor & Neuro-Oncology, Music & Medicine 14, 29 216-844-5500

Miller, Daniel W., MD Community Neurology, Comprehensive Stroke, Neuromuscular 17, 20, 35 216-844-7380

Miller, Jonathan, MDLeadership, Brain Tumor & Neuro-Oncology, Epilepsy, Functional & Restorative Neurosurgery, Music & Medicine, Parkinson’s & Movement Disorders, Spinal Neurosurgery, Traumatic Brain Injury

4, 14, 24, 25, 27, 29, 41, 43, 46 216-844-3470

Murray, Gail, PhD, MEd Music & Medicine 29 216-844-8168

Nock, Charles, MD Brain Tumor & Neuro-Oncology 14 216-844-3682

Ogrocki, Paula K., PhD Brain Health & Memory 9 216-464-6412

Onders, Raymond P., MD Neuromuscular 35 216-844-5797

Padrino, Susan, MD Brain Tumor & Neuro-Oncology, Neuropsychiatry 14, 38 216-844-3400

Park, Jun, MD Epilepsy 25 216-286-6644

Parrisbalogun, Stefani, MD Brain Tumor & Neuro-Oncology, Neuropsychiatry 15, 38 216-983-5650,

INDEX

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INDEX

Name Specialty Page Office Phone

Poreh, Amir, PhD Neuropsychiatry 38 216-983-3126

Preston, David C., MD Music & Medicine, Neuromuscular 29, 35 216-844-7776

Ravishankar, Kempsagar, MD Community Neurology 17 440-826-9221

Rhiew, Richard, MD Spinal Neurosurgery 43 440-816-2860

Robinson, Jenice, MD Neuromuscular 35 216-844-3495

Rodgers, Mark, MD Brain Tumor & Neuro-Oncology 15 216-844-3478

Rogers, Lisa, DO Brain Tumor & Neuro-Oncology 15 216-844-3717

Ronis, Robert J., MD Leadership, Music & Medicine, Neuropsychiatry 4, 29, 37 216-844-3883

Rorick, Mark, MD Community Neurology, Comprehensive Stroke 17, 20 440-285-2888

Ruedrich, Stephen, MD Neuropsychiatry 38 216-983-3088

Ryan, David, MD Functional & Restorative Neurosurgery 27 440-816-2850

Sajatovic, Martha, MD Leadership, Neurological & Behavioral Outcomes, Neuropsychiatry 4, 32, 38 216-844-2808 216-368-7572

Sawhny, Bhupinder, MD Spinal Neurosurgery 43 440-891-8880

Schilz, Robert, DO, PhD Music & Medicine 29 216-844-3201

Schlachet, Rebecca R., DO Neuropsychiatry 38 216-844-2400

Selman, Warren R., MD Leadership, Brain Tumor & Neuro-Oncology, Comprehensive Stroke, Spinal Neurosurgery, Traumatic Brain Injury 4, 15, 20, 43, 46 216-844-5745

Semaan, Maroun, MD Music & Medicine 29 216-844-8013

Serra, Alessandro, MD, PhD Community Neurology 17 216-844-3193

Shah, Binit, MD Brain Tumor & Neuro-Oncology, Neuropsychiatry 15, 38 216-844-3771

Shahid, Asim, MD Epilepsy, Functional & Restorative Neurosurgery 25, 27 216-286-3691

Shapiro, Barbara E., MD, PhD Functional & Restorative Neurosurgery, Music & Medicine, Neuromuscular 27, 29, 35 216-844-7768

Sila, Cathy A., MD Leadership, Comprehensive Stroke 4, 20 216-844-8934

Silverman, Paula, MD Brain Tumor & Neuro-Oncology 15 216-844-8510

Sloan, Andrew E., MD Leadership, Brain Tumor & Neuro-Oncology 4, 13 216-844-6054

INDEX

Name Specialty Page Office Phone

Stearns, Duncan, MD Brain Tumor & Neuro-Oncology 15 216-844-7400

Stralka-Larson, Amy, NP Parkinson’s & Movement Disorders 41 216-844-8285

Sundararajan, Sophia, MD Comprehensive Stroke 21 216-844-8421

Sunshine, Jeffrey L., MD, PhD Brain Tumor & Neuro-Oncology, Comprehensive Stroke 15, 21 216-844-3112

Supan, Erin, RN Leadership, Neuroscience Nursing Practice 4, 39 216-844-2413

Sweet, Jennifer, MD Epilepsy, Functional & Restorative Neurosurgery, Spinal Neurosurgery 24, 27, 43 216-983-3334

Syed, Tanvir U., MD Community Neurology, Comprehensive Stroke, Epilepsy 17, 21, 24 440-827-5061

Tangen, Rachel B., PhD Epilepsy 25 216-844-3230

Tani, Marie, MD Community Neurology 17 440-357-3100

Tarr, Robert W., MD Leadership, Comprehensive Stroke 4, 21 216-844-5722

Tien, Karen J., PhD Neuropsychiatry 38 216-844-6015

Tomcik, Colleen B., MD Community Neurology, Comprehensive Stroke 17, 21 440-735-4723

Tomei, Krystal, MD, MPH Brain Tumor & Neuro-Oncology, Traumatic Brain Injury 15, 46 216-844-5741

Walker, Mark, MD Community Neurology, Comprehensive Stroke 17, 21 216-286-0315

Walter, Benjamin L., MD Leadership, Functional & Restorative Neurosurgery, Music & Medicine, Parkinson’s & Movement Disorders 4, 27, 29, 41 216-844-8285

Walter, Ellen, NP Parkinson’s & Movement Disorders 41 216-291-2021

Weinberger, Leonard, MD Community Neurology, Neuromuscular 17, 35 440-357-3100

Winer, Norton A., MD Community Neurology, Comprehensive Stroke 17, 21 216-383-7850

Xiong, Wei, MD Comprehensive Stroke, Neurocritical Care 21, 31 216-844-0474

Zaraa, Solomon, MD Neuropsychiatry 38 216-983-3718

Zeiger, Todd, MD Traumatic Brain Injury 46 330-239-4455

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UHhospitals.org/Neuro • UH Neurological Institute | 5352 | University Hospitals • 216-844-2724

UH Case Medical Center11100 Euclid AvenueCleveland, Ohio 44106216-844-2724

The UH Neurological Institute offers unparalleled access and availability through its hub at UH Case Medical

Center and an ever-growing network of community facilities. The continued expansion of neurology,

advanced neurodiagnostics and neurosurgical capabilities at our community medical and health centers

brings our expertise and personalized care closer to home to those in outlying areas of Northeast Ohio.

Each of our systemwide locations have access to treatment options using advanced technology, such as:

neurostimulators for movement disorders, invasive monitoring and magnetoencephalography for epilepsy,

epilepsy surgical options, minimally invasive spine surgery and artificial disc replacement, image guided

neurosurgery, and endovascular therapy. In addition, all sites have access to leading-edge Stereotactic

Radiosurgery services, including Gamma Knife® and CyberKnife® therapy.

UH Ahuja Medical CenterKathy Risman Pavilion1000 Auburn Road, Suite 200Beachwood, Ohio 44122216-285-5115

Bolwell Health Center11100 Euclid Avenue, Suite 3100Cleveland, Ohio 44106216-844-2724

UH Bedford Medical Center44 Blaine AvenueBedford, Ohio 44146440-735-4775

UH Concord Health Center7500 Auburn RoadConcord Township, Ohio 44077216-844-2724

UH Elyria Medical Center630 East River StreetElyria, Ohio 44035

UH Foley ElderHealth Center3619 Park East Drive, Suite 211Beachwood, Ohio 44122216-464-6445

UH Geauga Medical Center13207 Ravenna RoadChardon, Ohio 44204440-285-6000

UH Geneva Medical Center870 West Main Street Geneva, Ohio 44041 440-466-1141

UH Landerbrook Health Center5885 Landerbrook DriveMayfield Heights, Ohio 44124216-844-2724

UH Medina Health Center4001 Carrick DriveMedina, Ohio 44256216-844-2724

UH Mentor Health Center9000 Mentor Avenue Mentor, Ohio 44060216-844-2724

UH Parma Medical Center7007 Powers BoulevardParma, Ohio 44129440-743-3000

UH Rehabilitation Hospital23333 Harvard RoadBeachwood, Ohio 44122216-593-2200

UH Richmond Medical Center27100 Chardon RoadRichmond Heights, Ohio 44143440-585-6137

St. John Medical Center29000 Center Ridge RoadWestlake, Ohio 44145440-835-6160

Southwest General Health Center18697 Bagley RoadMiddleburg Heights, Ohio 44130440-816-5050

UH Twinsburg Health Center8819 Commons BoulevardTwinsburg, Ohio 44087216-844-2724

UH University Suburban Health Center1611 South Green RoadSouth Euclid, Ohio 44121216-844-2724

UH Westlake Health Center960 Clague RoadWestlake, Ohio 44145216-844-2724

W.O. Walker Center10524 Euclid Avenue Cleveland, OH 44106Adult: 216-844-2400Pediatric: 216-844-3881

Northeast Ohio Locations – Refer patients to any of the following UH community locations.

LOCATIONS FOR NEUROLOGICAL CARE AT UNIVERSITY HOSPITALSCLINICIANS AND SCIENTISTS AT UH CASE MEDICAL CENTER AND

CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE

Warren R. Selman, MDHarvey Huntington Brown, Jr., Professor and ChairDepartment of Neurological SurgeryUH Case Medical Center and Case Western Reserve University School of MedicineNeurosurgeon-in-Chief and DirectorUniversity Hospitals Neurological InstituteChief of Division of Pediatric Neurosurgery, UH Rainbow Babies & Children’s Hospital

Anthony J. Furlan, MDChairman, Department of NeurologyUH Case Medical Center and Case Western Reserve University School of MedicineCo-Director, University Hospitals Neurological InstituteGilbert W. Humphrey Professor and Chair, Case Western ReserveUniversity School of Medicine

Francoise Adan, MDInstructor

Shahram Amina, MDAssistant Professor

Felipe Amunategui, PhDAssociate Director, Child &Adolescent Residency TrainingAssociate Professor

John Andrefsky, MDClinical Assistant Professor

Brian Appleby, MDAssociate Professor

Baha M. Arafah, MDDivision Chief and Fellowship Program DirectorClinical & Molecular EndocrinologyProfessor of Medicine

Fareeha Ashraf, MDClinical Instructor

Mirza Baig, MDClinical Assistant Professor

Christopher M. Bailey, PhDAssistant Professor

Nicholas C. Bambakidis, MDDirector, Cerebrovascular & Skull Base SurgeryProfessor and Vice Chair for Clinical Affairs

David Bardenstein, MDDirector, Center for Oculoplastics & Neuro-ophthalmologyProfessor of Ophthalmology

Christopher Bedosky, PhDAssistant Professor

Marek A. Buczek, MD, PhDAssistant Professor

Michael Coffey, MDAssistant Professor

Mark Cohen, MDAssistant Professor

Peter de Blank, MD, MSAssistant Professor

Suzanne Debrosse, MDClinical Assistant Professor

Michael DeGeorgia, MDDirector, Music & Medicine and Neurocritical Care CentersMaxeen Stone and John A. FlowerChair in NeurologyProfessor

Michael W. Devereaux, MDProfessor

Philipp Dines, MDDirector, Inpatient Geropsychiatry ServicesDirector, Geropsychiatry FellowshipAssistant Professor

Stefan Dupont, MD, PhDClinical Assistant Professor

Matthew Eccher, MD, MSPHAssistant Professor

Ciro Estabenez, MDAssistant Professor

Philip Fastenau, PhDDirector, Clinical NeuropsychologyProfessor

Steven Fulop, MD, MSClinical Assistant Professor

Keming Gao, MDClinical Director, Mood DisordersProgramMedical Director, ECTAssociate Professor

Stanton L. Gerson, MDDirector, University Hospitals Seidman Cancer Centerat UH Case Medical CenterDirector, Case Comprehensive Cancer Center at CaseWestern Reserve UniversityShiverick Professor of Hematologic Oncology

Joseph Gibbons, MDAssistant Professor

Rishi Goel, MDAssistant Clinical Professor

Deborah Gold, MDAssistant Professor

Cynthia Griggins, PhDAssistant Professor

Gerald E. Grossman, MDAssistant Professor

Steven A. Gunzler, MDAssistant Professor

John Hertzer, MDInterim Chief, Assistant Professor

Seth Alan Hoffer, MDDirector, Traumatic Brain Injury Center Co-Director, Neurocritical Care Center, UH Case Medical CenterDirector, NeurotraumaAssistant Professor

Jeffrey Janata, PhDDirector, Behavioral Medicine ProgramAssociate Professor

Bashar Katirji, MDDirector, Neuromuscular CenterProfessor

Camilla Kilbane, MDAssistant Professor

Henry B. Koon, MDAssistant Professor

Irina Korobkova, MDSenior Instructor

Jeanne Lackamp, MDDirector, Medical Student EducationAssistant Professor

Charles Lanzieri, MDAssistant Professor

Jonathan H. Lass, MDCharles I Thomas Professor

Zinaida Lebedeva, MDClinical Senior Instructor

Roseanna Lechner, MDClinical Assistant Professor

Jennifer Levin, PhDAssistant Professor

Alan J. Lerner, MDDirector, Brain Health & Memory CenterChair for Memory and CognitionProfessor

Samden D. Lhatoo, MD, FRCPDirector, Epilepsy Center Professor

Simon S. Lo, MDAssociate Professor

Joseph Locala, MDDirector, Neuropsychiatry Center Psychiatry & Medicine, Division DirectorDirector, Psychiatry & MedicineFellowshipAssociate Professor

Hans Lüders, MD, PhDProfessor

Janice A. Lyons, MDAssociate Professor

Mitchell Machtay, MDVincent K. Smith Chair in Radiation OncologyProfessor

James Mack, PhDAssistant Professor

Nicole Maronian, MDDirector, Voice CenterAssociate Professor

Molly McVoy, MDDirector, Child & AdolescentResidency TrainingAssistant Professor

Cliff A. Megerian, MDChairman of Otolaryngology – Head & Neck SurgeryRichard W. and Patricia R. PogueChair in Auditory Surgery and Hearing SciencesPresident, UH Physician ServicesProfessor

Daniel W. Miller, MDAssistant Professor

Jonathan Miller, MDDirector, Functional & RestorativeNeurosurgery Center,UH Case Medical CenterGeorge R. and Constance P.Lincoln Master Clinician inMemory Loss and BehavioralOutcomesAssociate Professor

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UHhospitals.org/Neuro • UH Neurological Institute | 5554 | University Hospitals • 216-844-2724

Gail S. Murray, MEd, PhD, CC-A, FAAAAssociate Professor

Charles J. Nock, MDAssistant Professor

Paula K. Ogrocki, PhDAssistant Professor

Raymond Onders, MDDirector, Adult Minimally Invasive SurgeryMargaret and Walter Remen Chair in Surgical Innovation Professor

Susan Padrino, MDAssistant Professor

Jun Park, MDClinical Assistant Professor

Stephani Parrisbalogun, MDSenior Instructor

Amir Poreh, PhDClinical Associate Professor

David C. Preston, MDProfessor and Vice ChairmanProgram Director, NeurologyResidency

Richard B. Rhiew, MD, PhDClinical Assistant Professor

Jenice Robinson, MDAssistant Professor

Mark Rodgers, MDAssistant Professor

Lisa R. Rogers, DODirector, Medical Neuro-OncologyProfessor

Robert J. Ronis, MD, MPHChairman, Department ofPsychiatry, UH Case Medical Center and Case Western Reserve UniversitySchool of MedicinePsychiatrist-In-Chief, University HospitalsDouglas Danford Bond Professor

Mark Rorick, MDDirector, Primary Stroke Center at UH Geauga Medical CenterClinical Associate Professor

Stephen Ruedrich, MDAdult Psychiatry, Division DirectorL. Douglas Lenkoski Professor

Martha Sajatovic, MDDirector, Neurological & Behavioral OutcomesCenter, Willard W. Brown Chair inNeurological OutcomesProfessor

Robert Schilz, DO, PhDDirector, Pulmonary VascularDisease and Lung TransplantationAssociate Professor

Rebecca Schlachet, DOSenior Instructor

Maroun Semaan, MDAssociate Director, Otology,Neurotology & Balance DisordersAssistant Professor

Alessandro Serra, MD, PhDAssistant Professor

Binit Shah, MDDirector, Psycho-Oncology ProgramSenior Instructor

Asim Shahid, MDAssistant Professor

Barbara E. Shapiro, MD, PhDDirector, Neuromuscular ResearchAssociate Professor

Cathy Sila, MDDirector, Comprehensive Stroke Center, George M. Humphrey IIChair in Neurology, Professor

Paula Silverman, MDAssociate Professor

Andrew E. Sloan, MDDirector, Brain Tumor & Neuro-Oncology CenterPeter D. Cristal Chair in NeurosurgeryVice Chair for Research Affairs and Professor

Duncan Stearns, MDAssistant Professor

Sophia Sundararajan, MD, PhDAssistant Professor

Jeffrey Sunshine, MD, PhDAssistant Professor

Jennifer Sweet, MDAssistant Professor

Tanvir U. Syed, MD, MPHAssistant Professor

Rachel Tangen, PhDAssistant Professor

Marie Tani, MDClinical Assistant Professor

Robert Tarr, MDAssociate Director, UH Neurological InstituteSection Chief NeuroradiologyProfessor

Karen Tien, PhDSenior Instructor

Colleen B. Tomcik, MDInstructor

Krystal Tomei, MD, MPHAssistant Professor

Mark F. Walker, MDAssociate Professor

Benjamin L. Walter, MDDirector, Movement Disorders Center Medical Director, Deep BrainStimulation (DBS) ProgramAssistant Professor

Leonard Weinberger, MDClinical Assistant Professor

Peter J. Whitehouse, MD, PhDProfessor

Norton Winer, MDClinical Assistant Professor

Wei Xiong, MDAssistant Professor

Solomon Zaraa, DOSenior Instructor

The commitment to exceptional patient care begins with revolutionary discovery. University Hospitals Case Medical Center is the primary affiliate of Case Western Reserve University School of Medicine, a national leader in medical research and education and consistently ranked among the top research medical schools in the country by U.S. News & World Report. Through their faculty appointments at Case Western Reserve University School of Medicine, physicians at UH Case Medical Center are advancing medical care through innovative research and discovery that bring the latest treatment options to patients.

Physicians receive their academic appointments and their accompanying titles from Case Western Reserve University School of Medicine.

CLINICIANS AND SCIENTISTS AT UH CASE MEDICAL CENTER AND CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE

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© 2015 University Hospitals NEU 00440

UH Lyndhurst, Mentor and Westlake surgery centers, extensions of University Hospitals Case Medical Center.

Among the nation’s leading academic medical centers, University Hospitals Case Medical Center is the primary affiliate of Case Western Reserve University School of Medicine, a nationally recognized leader in medical research and education.