2012 enzo life sciences capabilities presentation

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Enzo Life Sciences Scientists enabling scientists

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Enzo Life Sciences Capabilities Presentation

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Page 1: 2012  Enzo Life Sciences Capabilities Presentation

Enzo Life SciencesScientists enabling scientists

Page 2: 2012  Enzo Life Sciences Capabilities Presentation

Scientist enabling scientists

For over 30 years, Enzo has been providing enabling technologies for the research, development, development, manufacture, licensing and marketing of innovative health care products, platforms and services based on molecular and cellular technologies.

Page 3: 2012  Enzo Life Sciences Capabilities Presentation

Enzo Biochem

Enzo (ENZ)• Founded in 1976 • Company led by

Dr. Elazar Rabbani• Ph.D in Biochemistry• Company founder • Company founder

Page 4: 2012  Enzo Life Sciences Capabilities Presentation

Segmented to align with our customer needs

Enzo (ENZ)• Divided into 3 segments:

Life SciencesClinical LabsTherapeutics

• 500+ employees globally

• 40,000+ product portfolio focused on the research market.

Page 5: 2012  Enzo Life Sciences Capabilities Presentation

Enzo Biochem Family

Enzo Biochem

Enzo Clinical Labs

Enzo Life Sciences

EnzoTherapeutics

Enzo Direct

Axxora

Page 6: 2012  Enzo Life Sciences Capabilities Presentation

Segmented to align with our customer needs

Enzo Biochem (ENZ) : FY2010

FY2010 Life Sciences

Therapeutics Clinical Labs Other Consolidated

Revenues* $52,904 $ - $44,178 $ - $97,082

Operating Expenses*

49,742 2,502 51,727 - 119,140Expenses*

Operating Income*

3,162 (2,502) (7,549) (15,169) (22,058)

14% investment in R&D(*,000)

Page 7: 2012  Enzo Life Sciences Capabilities Presentation

Global Reach

Enzo Life Sciences has offices across the globe to ensure efficient service & delivery to our customers.

ELS Headquarters

Research, Manufacturing, Customer Service sites

Page 8: 2012  Enzo Life Sciences Capabilities Presentation

Enzo Life Sciences –Increasing focus in key scientific areas

- Leverage originsEnzo established itself as a leader within the Molecular Biology market space. Today, we still serve that area, but also rely on those roots to complement our efforts within other life science spaces.

- Acquisitions in key areasExpertise expanded with the acquisition of Expertise expanded with the acquisition of several technology companies including:

- 2007: Alexis Biochemicals- 2008: Biomol International- 2009: Assay Designs / StressGen

- Sales Channels- Direct ELS products- Distribution network- Axxora company

Page 9: 2012  Enzo Life Sciences Capabilities Presentation

Enzo Life Sciences Market Focus

Cellular Analysis

Molecular Biology

Small Molecule Chemistry

Proteostasis& Epigenetics

Custom Services

Page 10: 2012  Enzo Life Sciences Capabilities Presentation

Cellular Analysis

Quality products enabling a unique array of possibilities in cell detection & characterization

• Live Cell analysis kits• High Content Screening• Organelle visualization• In Vitro Toxicology

• Cellestial Dyes include fluorescent probes that offer

Cellular Analysis

Live Cell AnalysisCellestial Dyes

AntibodiesProteins

Reagents

• Cellestial Dyes include fluorescent probes that offer broadest range of excitation & emission profiles

• Assays compatible with flow cytometry, fluorescent microscopy and microplate formats

– Autophagy detection by flow cytometry• Wide portfolio of proteins, antibodies & reagents for

analysis of cell processes and response• Apoptosis reagents• Inducers, inhibitors & detection solutions for

studying oxidative stress

Page 11: 2012  Enzo Life Sciences Capabilities Presentation

Drug Development

Let our experience work for you

• Unique collection of focused Screen-Well™ compound libraries

• Current catalog of over 3,000 stand-alone small molecules including;

• Natural products• Enzyme inhibitors• Receptor ligands

Small Molecule Chemistry

Screen-Well™ Compound Libraries

Unique small molecules

• Receptor ligands• Drugs• Lipids• Fatty acids

• Global Sourcing capabilities thought a supplier network built on more than 25 years of experience.

Page 12: 2012  Enzo Life Sciences Capabilities Presentation

Molecular Biology

Established products enabling high sensitivity

• BioArray® RNA Amplification & labeling systems and cDNA synthesis kits offer a convenient all-in-one system for gene expression analysis

• Comparative Genomic Hybridization (CGH) analysis products are specifically optimized and validated for

Molecular BiologyBioArray Kits

CGH labeling KitsFluorescent dUTPs

products are specifically optimized and validated for both BAC and oligonucleotide arrays

• Superior DLR scores• Validated for high density arrays

• A comprehensive portfolio of high quality modified nucleotides and nucleic acid labeling systems providing all the necessary tools for in situ hybridization and FISH applications

• Fluorescent dUTPs, and Nick Translation DNA Labeling kits

Page 13: 2012  Enzo Life Sciences Capabilities Presentation

Proteostasis

Enabling discovery across a wide network of protein processes.

• Detection & characterization products for a multitude of processes central to proteostasis:

• Protein synthesis, folding and unfolding• Post-translational modification• Protein degradation

• Most comprehensive heat shock protein portfolio

Proteostasis& EpigeneticsProteoStat™ Detection

AssaysUbiQapture Kits

ELISA KitsHDAC kits

• Most comprehensive heat shock protein portfolio available.

• Only HSP70 validated for plasma & serum• Only source for HSP70B ELISA

• ProteoStat™ assays for characterization, formulation and process development of protein therapeutics

• Sensitive aggregation detection assays• Protein A ELISAs for contamination

detection• Drug Discovery kits

• Epigenetics• Proteases• Caspases

Page 14: 2012  Enzo Life Sciences Capabilities Presentation

Valued partner in the Life Sciences arena

- A solid infrastructure build on 30 years of business acumen.

- An established global network to efficiently supply product and provide timely technical support.

- Strong R&D investment to keep a continued stream of innovative products flowing to the market.

- 1,000s of scientific references supporting our broad portfolio of reliable products.

- Leading scientists regularly collaborating with our customers to stay connected and produce thoughtful products.

Page 15: 2012  Enzo Life Sciences Capabilities Presentation

Enzo Life SciencesScientists enabling scientists

Page 16: 2012  Enzo Life Sciences Capabilities Presentation

Enzo Life Sciences Brands

Enzo Life Sciences

Alexis BioMol Assay Design StressGen Enzo legacy brand

ALX BML ADI

BPD

ADI ENZ