2010 fall/winter

STUNNING PERFORMERS dazzlE THE 19TH CaROUSEl OF HOPE BENEFITING CHIldREN’S dIaBETES FOUNdaTION

conicartistsJenniferLopezandMarc Anthony,GladysKnight,AkonandJay LenojoinedwithHonoreesMariaShriver andQuincyJonesandpresenters

TomHanks,RitaWilsonandRandyJackson,ProducerGeorgeSchlatterandMusicDirectorRickeyMinortomakethe2010Mercedes-BenzCarouselofHopethemostglittering,glamorousandgorgeouseventinthe24-yearhistoryofTheCarouselofHopebenefitingtheBarbaraDavisCenterforChildhoodDiabetesandtheChildren’sDiabetesFoundation.

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children’s diabetes foundation at denver — Winter 2010

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1. Jay Leno

2. Maria Shriver, Honoree

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4. Dana Davis, Barbara Davis

5. Raquel Welch

6. Kenny Rickel, Paul and Lynn Palmer, Isabella and Mariella Rickel, Nancy Davis Rickel

ON THE COVER

1. Tom Hanks, Rita Wilson, Barbara Davis, Maria Shriver, George Schlatter

2. Halle Berry

3. Marc Anthony and Jennifer Lopez, Featured Performers

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1. Garcelle Beauvais

2. Gladys Knight, Featured Performer

3. Clive Davis, Stevie Wonder, Barbara Davis

4. Nancy O’Dell

5. Kelly & Don Johnson

6. Barbara Davis, Daisy Fuentes

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1. Qunicy Jones, Honoree

2. Cheryl Tiegs, Frances Fisher

3. Garcelle Beauvais, Paul Sorvino

4. Larry Gilman, Donna Mills

5. Gladys Knight, Lisa Raye McCoy

6. Vanna White

7. Don Rickles, Kathy Griffin, Bob Newhart

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1. Bob Evans & Guest

2. Jennifer Lopez

3. Bob Daly, Barbara Davis, Carole Bayer Sager

4. Harrison Fuller

5. Lara Spencer

6. Nigel Lythgoe, Alana Stewart, Marc Anthony

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1. Halle Berry, Olivier Martinez

2. Berry Gordy, Eskedar Gobeze

3. Percy Gibson, Joan Collins

4. Sidney and Joanna Poitier

5. George and Jolene Schlatter

6. Brandy, Maksim Chmerkovskiy, Lisa Rinna, Harry Hamlin

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1. Barbara Davis, Adrien Brody

2. Akon

3. Sela Ward

4. Alan Thicke, Tanya Callau

5. Paris Hilton

6. Dr. Nancy Larco, Head of Diabetes at Medecine Interne Maladies Metabolique and Dr. Philippe Larco, leading Haitian Immunologist, who returned to Port au Prince the day after the Ball to help with the Cholera epidemic

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1. Rickey and Karen Minor

2. Barbara Davis, Steven Graham Angelica Huston

3. Christopher Backus, Mira Sorvino

4. Gregg Davis, Barbara Davis, Harry Davis, Elena Davis, Hudson Davis, Julie Davis

5. Kathy and Rick Hilton

6. Robert & Kelly Day

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1. Jackie Collins, Dieter Abt

2. Julie Chen, Les Moonves, Leah Remini

3. Marc Anthony

4. Savannah Robinson

5. Randy Jackson

6. Lili Zanuck, Barbara Davis, Sherry Lansing

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the2010CarouselofHopeBallpresentedbyMercedes-Benz,raisingnearly$2.4millionforresearchandclinicalcareprogramsfordiabetesattheBarbaraDavisCenterforChildhoodDiabetes,whereover5,000childrenandadultsreceivecare.

TheeveningwouldnotbepossiblewithoutthehelpofgeniusTVveteran,GeorgeSchlatterandhisskilledproductioncrew,talentedmusicdirector,RickeyMinor,andJayLeno,whoonceagainreprisedhisroleastheMasterofCeremonies.

TheChildren’sDiabetesFoundationwouldliketothanktheevening’spresentingsponsorMercedes-BenzUSA,andmajorsponsorsGUESS?,AmericanAirlines,sanofi-aventisU.S.,TheBeverlyHiltonHotelandourangelsponsorsRonBurkle,SarahSiegel-MagnessandGaryMagnessandRobertandKellyDay.ReemAcrailluminatedtheballroomwithherbeautifuldonatedtableclothsinshadesofpink.Lushflowerarrangementswithover10,000flowersflowninfromEcuadorwerecreatedbyFredGibbonsofTreefrogs,whohasservedastheevent’sexclusivefloristsince1990.WealsothankAngelicaHustonforallowingustousethesculpturesofthelatebelovedRobertGrahamforthehonoreeawards,andMoëtHennessyUSA,ourexclusivespiritssponsor.Theeveningwasalsogenerouslysupportedbymanycorporationsandleadersfromtheentertainmentindustry.

TheshowbeganwithSavannahRobinson’sacapellarenditionofthe“StarSpangledBanner.”TomHanksandRitaWilsonthenintroducedFirstLadyofCalifornia,MariaShriver,whowastherecipientoftheBrass

RingAwardforherinspiringhumanitarianefforts.Maria’smeaningfulspeechdeeplytouchedtheaudience.Lastyear’sBrassRinghonoree,CliveDavis,followedwithawarmintroductionofBarbaraDaviswhogenerouslythankedeveryguestforattendingandjoininginthefightagainsttheglobalepidemicofdiabetes.SheupdatedtheaudienceontheCenter’sprogramsandtheadvancesbeingmadeforchildreneverywhere.Inclosing,shementionedaquotefromChristopherReeve,“Onceyouchoosehope,allthingsarepossible.”AmericanIdol’sRandyJacksonwelcomedQuincyJonestothestageashewashonoredwiththeFoundation’sdistinguishedHumanitarianAwardonthe25thAnniversaryof“WeAreTheWorld.”

TheunforgettableeveningincludedperformancesbygreatartistsJenniferLopezandMarcAnthony,whoperformedaduetof“NoMeAmes.”Togetherthecouplesanginperfectharmonylightinguptheroomwithloveandsong.JenniferLopezthentookcontrolofthestageinafieryperformanceof“Let’sGetLoud”,whichsetthetonefortheeveningofentertainmentaseachpersonintheroomwassinginganddancing.AmericanR&BsingerandsongwriterAkonwasnextasheruledthestage,performinghishitsongs“Angel”and“SexyChick.”TheFeaturedPerformer,legendaryartistGladysKnight’sgrandfinalehadguestsontheirfeet,swayingandsingingwithhertoclassics“NeitherOneofUs”and“MidnightTraintoGeorgia”leavingeveryoneeuphoricallywishingformore.

Someofthemanycelebratedguestsincluded:HalleBerry,StevieWonder,AdrienBrody,JackieCollins,JoanCollins

andPercyGibson,CliveDavis,JaneFonda,BerryGordy,KathyGriffin,TomHanksandRitaWilson,AnjelicaHuston,RandyJackson,RickeyMinor,LesMoonvesandJulieChen,DermotMulroney,BobandGinnyNewhart,JoannaandSidneyPoitier,DonandBarbaraRickles,CaroleBayerSagerandBobDaly,JoleneandGeorgeSchlatter,JudgeJudySheindlin,RodStewartandPennyLancaster,SelaWard,RaquelWelch,VannaWhite,GarcelleBeauvais,ThoraBirch,Brandy,MaksimChmerkovskiy,BillyDavis&MarilynMcCoo-Davis,BobEvans,FrancesFisher,DaisyFuentes,LisaRinna&HarryHamlin,NickyHilton,ParisHilton,Rick&KathyHilton,BeverlyJohnson,DonJohnson,TamalaJones,SusanLucci,NigelLythgoe,ChrisMassey,KyleMassey,BennyMedina,DonnaMills,NancyO’Dell,SumnerRedstone,LeahRemini,MimiRogers,MiraSorvino,PaulSorvino,LaraSpencer,AlanaStewart,AlanThicke,CherylTiegs,LouisvanAmstel,BuzzAldrin,JoanvanArkandBenVereen.

DuringtheliveauctiononeluckywinnerwalkedawaywiththestunningMercedes-Benz2011CL63AMGfor$170,000.TheliveauctionalsoincludedtwoincredibletripscourtesyofSt.RegisHotels,onethroughoutEuropeandanothertoHawaiiandTibet,withairfaretobeginandendthetripsdonatedbyAmericanAirlines.

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TheSilentAuction,chairedbyNancyDavisandDanaDavis,wascomposedofnearly450itemsandincludedanAvjettripfor7toLasVegasorMontereyonaGulfstream150orHawker800XP.OthervacationspotsincludedstaysatTheResortatPelicanHillinSouthernCalifornia,thePeninsulaHotelinHongKong,HotelLeBristolinParisandtheGrandWaileaResortHotelandSpainHawaii.Lavishdiningexperiencesincluded:dinnerfor20intheprivatediningroomatMr.Chow,WolfgangPuckdinnerfor12atCUTwithwines;IlPiccolino;Toscana;ChateauMarmont;TheFrenchLaundry.FashionitemsthisyearfeatureddonationsfrommanyfashioniconssuchasDonnaKaran,GiorgioArmani,Chanel,MoniqueLhuillier,OscardelaRenta,Fendi,DeviKroell,SaksFifthAvenue,NeimanMarcusandmore.OtherAuctionitemsincludeddonationsfromhometeamstheLALakers,andLADodgers;jewelryfromTiffany&Co.andNancyDavis’PeaceandLove;andthepopularArtGallerywithartdonatedbyleadingcontemporaryartistssuchasEdRuscha,thelate

DennisHopper,TonyBennett,RossBleckner,NancyEllison,FrankGehry,LeRoyNeiman,FiroozZahediandmanymore.

Celebritiesonceagainhelpedinseveralways,includingMAKELOVENOTTRASHtotespersonallysignedbyKenny“Babyface”Edmonds,SelmaBlair,GeorgeClooney,ClintEastwood,HarrisonFord,ScarlettJohansson,BillMaher,JuliaLouis-Dreyfus,MikeMyersandBenStiller.HandbagsforHopewassupportedbycelebritiesShirleyMacLaine,MariaShriver,KellyPreston,CindyCrawford,AngelaBassett,CandiceBergen,CarolBurnett,JoyBehar,GoldieHawn,JackieCollins,AnjelicaHuston,JulianneMoore,ThoraBirchandJoanvanArkwhodonatedoneoftheirspecialhandbagsandautographedkeychainsbyLineaPelleandBraggables.

BrandnewthisyearwasCanvasfortheCure,aprojectthatfeaturedoriginalminiaturecanvasespaintedbycelebritiesincludingartbyJohnTravolta,AnjelicaHuston,JoshGroban,GeorgeClooney,CindyCrawford,BillMaher,PennyMarshall,

CrystalBowersoxandmanymore.

Thisyear’swonderfulgiftbagsdesignedbyGUESS?,includedanextraordinaryarrayofgenerousgiftsfromGUESS?includingascarf,eyewear,men’sandwomen’swatches,alsodonationsfromtheLosAngelesLakers’,MAC,TheWaltDisneyCompany,JackieCollins,UrbanBehavior,TinaSinatra,Wen,CaritaUSA,Decléor,Avjet,AmandaDunbar,BagatellaHandbags,BeverlyHillsPlasticSurgery,CanvasPop,MSalon,OPI,NubiusOrganics,RavenSpaandtheRanch.

TheCarouselofHopehasraisedmorethan$75millionsince1978tocriticallycombatthediabetesepidemic,whichafflictsoneinthreebabiesborntoday.TheseessentialfundsareraisedbyChildren’sDiabetesFoundationtofundprogramsformorethan5,000childrenandadultswhoreceivespecializedcarefordiabetesmanagementandpreventionofcomplicationsandonreachingforthecure.

1. Barbara Davis

2. Mavis & Jay Leno

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2010

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he2010Carousel ofHopeDiabetes Symposium, “Pathwaysfor FutureTreatmentandManagementofDabetes,”addressednewinsulindeliverysystemsincludingcontinuousglucosemonitoring.Italsoconcentratedonneworalmedicationsfortype2diabetesalongwiththeemergingincreaseinobesityandtype2diabetesinchildrenandyoungadults.TheSymposiumassembledagroupofexpertswhoseworkengageswiththemulti-facetedchallengesfacingtheimplementationofthisnewtechnologytobenefitofpeoplewithdiabetes.

Jeffrey A. Bluestone, PhD, A.W. and Mary Margaret Clausen Distinguished Professor; former Director of the Diabetes Center at the University of California, San Francisco at the University of California, San Francisco, CADr.BluestoneestablishedtheUCSF/JDRFCenterforIsletTransplantationandservesontheCaliforniaInstituteforRegenerativeMedicineDiabetesDiseaseTeam,aswellascomprehensiveresearchandclinicalprogramsaimedatmarryingcutting-edgeisletcell-specificstemcellbiologywithnovelimmunotherapiesasatreatmentfortype1diabetes.

Tprofitorganizationwiththemissionofeducatingandmotivatingpeoplewithdiabetestotakeamoreactiveroleintheircondition.

Dr. George Eisenbarth, MD, PhD, Executive Director of the Barbara Davis Center for Childhood Diabetes and Professor of Pediatrics, Medicine, and Immunology at the University of Colorado School of Medicine, Aurora, CO Dr.Eisenbarthfirstcharacterizedtype1diabeteswhileatJoslinasachronicautoimmunediseasethatcouldbepredictedpriortoclinicalsymptoms.Hisimmunogeneticslabinvestigatesautoimmunityinnaturalhistorystudies,includingtwins,andintheNODmousewiththegoalofpredictingandpreventingdiabetes.HeisreceivedADA’s2009BantingPrizeforOutstandingLifetimeScientificAchievement.

Satish K. Garg, MD, MBBS, DM, Director, Adult Clinic, Barbara Davis Center, Professor of Medicine and Pediatrics, University of Colorado Health Sciences Center, Aurora, CO Dr.Garg¹sresearchinterestsincludetheearlydetectionandtreatmentofrenalandretinalcomplicationsoftype1diabetesandthedevelopmentofnewdiagnosticandtherapeutic

Peter Butler, MD, Professor of Medicine, Chief of the Division of Endocrinology, Diabetes and Hypertension and Director of Larry Hillblom Islet Research Center, University of California, Los Angles, CA Dr.ButlerisaclinicalinvestigatorwithclinicalpracticeatUCLAfocusingoncareofpatientswithdiabetesandresearchfocusingonabnormalinsulinsecretion,thecausesofbetacelldeathandthepossibilitytofosterisletregenerationinhumans.

Steve Daniels, MD, PhD Chairman of the Department of Pediatrics at the University of Colorado School of Medicine, Aurora, CO Dr.DanielsisaPediatricCardiologistwhohasfocusedhisclinicalworkandresearchonPreventiveCardiology.Hisinterestsincludetheeffectsofdiabetes,hypertensionandobesityonthecardiovascularsystem.

Steve Edelman, MD, Professor of Medicine in the Division of Endocrinology, Diabetes & Metabolism at the University of California at San Diego (UCSD), CA and the Veterans Affairs (VA) Healthcare System Dr.EdelmanisalsothefounderanddirectorofTakingControlofYourDiabetes(TCOYD),anot-for-

THE CaROUSEl OF HOPE dIaBETES SyMPOSIUM

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2010 Sym

posiumtoolsrelatedtoclinicaldiabetesmanagementthatincludenewinsulinanalogsandglucosesensors,etc.HecurrentlyservesastheEditor-in-ChiefoftheDiabetesTechnologyandTherapeuticsJournal.

Matthias Hebrok, PhD, Hurlbut-Johnson Distinguished Professor in Diabetes Research, Interim Director of the Diabetes Center, University of California, San Francisco, CA Dr.Hebrok’sresearchfocusesontheunderstandingofhowisletsofLangerhans,theendocrinecomponentofthepancreas,areformedduringorganogenesis,howtheirfunctionisregulatedinthematureorganismandhowchangesingeneexpressionmightallowisletregeneration.

John C. Hutton, PhD, Research Director, Barbara Davis Center; Professor, Department of Pediatrics and Cellular and Structural Biology, University of Colorado Denver, Aurora, CODr.Hutton’slaboratoryprovidesastrongtrainingenvironmentinmolecularcellbiology,biochemistryandimmunologyemphasizingbasicresearchoninsulinsecretionandthepathogenesisoftype1diabetes.HeheadstheDiabetesand

EndocrinologyResearchCenterattheBarbaraDavisCenterandtheJDRF-BDCAutoimmunityPreventionCenter.

Marian Rewers, MD, PhD, Clinical Director, Barbara Davis Center, Aurora, CODr.RewersisProfessorofPediatricsandPreventiveMedicineattheUniversityofColoradoandisapediatricdiabetologistandaninternationally-recognizedphysicianscientist.Hehasmadeimportantcontributionstoourunderstandingoftheetiologyoftype1diabetesanditsmacrovascularcomplicationsbycreatinglargeprospectivecohortstudies:DAISY,CACTIandaninternationalconsortium,theEnvironmentalDeterminantsofDiabetesintheYoung(TEDDY).

Jay S. Skyler, MD, MACP, Professor of Medicine, Pediatrics, & Psychology at the University of Miami, Miami, FLDr.SkylerisAssociateDirectorforAcademicProgramsintheDiabetesResearchInstituteandisChairmanoftheNIH-sponsoredType1DiabetesTrialNet,aninternationalnetworkconductingclinicaltrialstopreventtype1diabetesorinterdictthetype1diabetesdiseaseprocess.

Dr. Robert Slover, MD, Director of Pediatric Clinical Services, Barbara Davis Center, Aurora, CODr.SloveristheColoradoprincipalinvestigator(PI)fortheSTAR3study.STAR3isarandomized,multi-centertwo-armstudytocomparetheefficacyoftheMiniMedParadigmREAL-Timesystemversusmultipledailyinjections(MDI).Hehasbeeninvolvedin12researchprojectsaseitherPIorCo-PI,has12publicationsandhasbeeninvitedtoover35speakingengagements.

Phil Zeitler, MD, PhD, Professor of Pediatrics and Clinical Science at the University of Colorado Denver and Medical Director of the Children¹s Hospital Clinical Translational Research Center of the Colorado Clinical Translational Science Institute, Aurora, CO Dr.ZeitlerisAttendingEndocrinologistattheChildren¹sHospitalandtheBarbaraDavisCenterforDiabetes,whereheisDirectoroftheType2DiabetesandMetabolicSyndromeClinicandDirectorofthePediatricEndocrinologyTrainingProgram.HecurrentlyservesasStudyChairofTODAY,anational,NIH-funded,multi-centertrialexaminingtreatmentoptionsforadolescentswithtype2diabetesandTODAYGeneticsStudy.

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2010 Davis awarD winnerJEFFREy A. BLUESTOnE, PhD Duringthepast25years,Dr.Bluestonehasauthoredover375publicationsondiabetesandimmunitywhilestudyingtheregulationofT-cellsinresponsetoautoantigensandtransplantationantigens,supportingthedevelopmentofhelpinthedevelopmentofanewgenerationoftolerogenicdrugsthatwill“turnoff”selectedpartsoftheimmunesystem,leavingthedisease-fightingcapabilitiesintact.HehasreceivednumerousawardsincludingtheJDRFGrodskyBasicScienceAward,theMaryTylerMoore&RobertLevineExcellenceinClinicalResearchAwardandaJDRFScholarAwardfromJDRF,aswellastheAmericanSocietyforTransplantationRocheDistinguishedResearchAward.

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ype1diabetes isoneofthe mostcommon chronicdiseases inchildren.Unfortunately,thefearoflowbloodsugars(hypoglycemia)preventsmanyfamiliesfromachievinggoodcontrolofthediabetes.Hypoglycemiaisscary,andwhenseverecanresultinseizuresorunconsciousepisodes.Althoughexerciseisrecommendedforallyouthwithregulardiabetes,hypoglycemiaduringorafterexerciseisoneofthemostfrequentlyidentifiedspecificcausesofseverehypoglycemia.

ThreelandmarkstudiesintheCTRC(ClinicalTranslationalResearchCenter)atChildren’sHospitalhavebeenimportantinmakingexercisesafeforchildrenwithType1diabetes.Thefirsttwostudieshavebeenperformedaspartofaworkinggroup(DirecNet)ofpediatricendocrinologistsattheBarbaraDavisCenter/DenverChildren’sHospital,YaleUniversity,StanfordUniversity,Nemour’sChildren’sHospitalinFlorida,andtheUniversityofIowawithcoordinationbytheJAEBCenterforHealthResearchinTampa,Fl.

Aninitialstudydevelopedthe60minutetreadmillmethodologyusedinalllaterstudies.Theinitialstudyfoundthatduringtheexercise,oneoutoffourofthechildrenhadbloodsugarlevelsbelow60mg/dLandhalfofthechildrenhadvaluesbelow70mg/dL.ThechildrenstayedinChildren’sHospitalovernighttostudytheincidenceofdelayednocturnalhypoglycemia(lowbloodsugarlevels).Surprisingly,lowsoccurred

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laNdMaRk STUdIES ON ExERCISE aNd HyPOGlyCEMIa IN yOUTH wITH TyPE 1 dIaBETES

— H. Peter Chase, MD and Rosanna Fiallo-Scharer, MD

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rduring48%ofnightsfollowingadaywhenthechildrenhadexercised,andon28%ofnightswhenthesameyouthspentthenightinthehospitalafteradaywithoutexercise.ThiswaspublishedintheJournalofPediatrics147:528,2005.

Animportantsecondstudyfocusedonpreventingthelowbloodsugarsduringtheafternoonexercisesession.Youthusinganinsulinpumpturnedoffthepump(noinsulin)duringthe60minutesofexerciseandfor45minutesaftertheexercise.Lowbloodsugarswereapproximately1/3ascommonwhentheinsulinwasdiscontinued(16%ofchildren)asonanotherdaywheninsulinwascontinuedforthesameyouth(48%low).ThiswaspublishedinDiabetesCare29,2006.

Inathirdstudy(currentlyinpress:JournalofPediatrics),Dr.CraigTaplin(a3rdyearEndocrine-DiabetesfellowatTheChildren’sHospital/BarbaraDavisCenterstudiedmethodstopreventthedelayedlowbloodsugarsduringthenight.Thesameafternoonexerciseprogramwasusedas

inthetwoabovestudies.Hefoundthatdiscontinuationoftheinsulinduringexerciseandadministrationofhalfoftheusualinsulinfor45minutesaftertheexercise,followedbya20%reductionofbasalinsulinfrom9pmto3amessentiallypreventedlownighttimebloodsugars.Asthesechangesininsulindeliveryareonlypossibleforyouthusinganinsulinpump,theadministrationofamedicine,terbutaline,wasalsostudied.Thiscanbeusedbyyouthusinginjectionsandnotusinganinsulinpump.Thismedicinepreventedlowbloodsugarsatnightbutcausedbloodsugarlevelstobetoohigh.Furtherstudieswillbeneededtodeterminethecorrectdoseofterbutaline.

Insummary,knowledgefromthesethreelandmarkstudies,alldoneincollaborationwithTheChildren’sHospitalandtheBarbaraDavisCenterforChildhoodDiabetes,shouldhelptomakelifesaferandeasierforthe3,000childrenwithType1diabetesfollowedattheCenter,aswellasforthemillionsofchildrenwithdiabetesaroundtheworld.

IMPORTaNT wEBSITESChildren’s Diabetes Foundation

www.ChildrensDiabetesFoundation.org

Barbara Davis Center for Childhood Diabetes www.BarbaraDavisCenter.org

Juvenile Diabetes Research Foundation www.jdrf.org

American Diabetes Association www.diabetes.org

Children with Diabetes www.ChildrenwithDiabetes.com

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TaMING THE SHOT MONSTER

— Rita Trujillo Hughes, LCSW, CDE, Clinical Social Worker

ustaminute...” “Ihavetogo dosomething first....” “You’re mean!”“I HATESHOTS!”

Soundfamiliar?Areshotsorsetchangesatyourhouseastruggleandabattle?Youarecertainlynotalone.Preliminarystudysuggeststhatperhapsathirdofallchildren,teensandadultshavesomedegreeofneedleanxietythatmakesinjectionsachallenge.However,themajorityofthesekidsdon’tnecessarilysaythatshotshurt.Theirbehaviortellsusso.Needlefearsrangeindegreefrommildtosevere.Trueneedlephobia(wherethelevelofanxietyissoheightenedthatpeoplemightfaintatthesightofasyringe)islesscommon,but

needlefearfulnessisnonethelessveryimportanttoaddress.Itisimportanttoknowthatanxietyaboutshotsismediatedbyarealbiologicalresponse.Thephysicalsymptomsarereal.Queasystomach,sweatypalms,shakyhands,andpoundingheartsarenotuncommon.

Sometimes,painwithshotstriggersanxietythatcanleadtodifficultieswithinjections.Incorrectinjectiontechniquemaybecausingsomepain.Thoughweknowthatshotsaren’tgoingtobeabsolutelypainless100%ofthetime,withproperpreparationandtechnique,shotsshouldberelativelypainfreemostofthetime.Shotsoughttofeellikeasmallpinch(atleastthat’swhatwestrivefor).Coldinsulinandsometypesofinsulinmightbecontributingtodiscomfortandtheseareissuesthatyournurseeducatorcanreviewwithyouandmakesuggestionsthatmightmakearealdifference.

Ifchangingtechniquedoesn’tworkandyourchildhassomeofthefollowingsymptoms,thenconsultingoneoftheclinicalsocialworkersontheteammighthelp.Evenwhenkidsdon’tcomplainofanxietyorpainfulshots,thesebehaviorssuggestthatwemayneedtolookalittlecloser:

*Yourchildstallsaroundshotsorhaselaborateritualsabouthowtheyshouldbedone.

*Takesalongtimetoactuallydotheinjectionor“huntsandpecks”lookingforjusttherightspot.

*Refusestorotatesitesandhasafavoritespotthatusuallyendsuppuffyfromoveruse.

*Demandscontrolandrefuseshelpwithinjectionsfromanyone,evenwhenhelpfromaparenthasbeenrecommendedbythedoctor.

*“Forgets”todoshotsorevenskipssomeinjections.

*ApersistentlyhighA1cevenwheninsulinisincreased.

*Youngchildrenconsistentlycryaboutshotsandparentsfeeltheyhavetowrestlewiththeminordertogetthejobdone.

Whenkidsanticipateandexpectpainwithaninjection,theymaybegindoingthingsthatactuallyheightentheiranxietyandtheirperceptionofpain.Forexample,theymayholdtheirbreathandtensetheirbody.Theymaywiggleandstruggle,makingitmoredifficultforaparenttodoaninjectioneasily.Thesebehaviorswillprobablymakeshotshurtmoreandthelongerthestrugglecontinues,theharderitistochange.

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needle Anxiety (Fear of shots)Itisnowknownthatneedleanxietyofsomedegreeoccursinalmosteveryone.Childrenandadultshaveworriesaboutshots.Inapersonwithdiabetes,weusedtoassumethatthisanxietywouldjustgoawaybecausetheyhadtohaveshotseveryday.Wenowknowthatneedleanxiety,ifstrong,doesn’t“justgoaway”.Therearesomethingsthatcanbelearnedtoreducethisanxietyifweidentifyitisaproblem.

Firstofall,anxietyaboutshotsisnormal.Whenwefearsomething,wegettenseandholdourbreath.Ourheadisfilledwiththoughtsaboutpain.Parents,whohavetogivetheseshots,canbejustasneedleanxiousastheirchild.Remember,thatthesyringesthatarenowusedforinsulinaremuchsmallerandhaveshorterneedlessothatshotsaremuchmorecomfortablethesedays.Withafeweasytechniques,shotscanbelessstressful.Thediabeteseducatorsinourclinicalwayshaveparentsorsignificantotherspracticeinjectionsoneachotherusingsalinesolution.Thepracticenearlyalwaysreassuresthemthatgivinginsulininjectionstotheirchildisnotthetraumatheyimage.

Tensingcanmakeshotshurt.Sotakeacoupleofdeeprelaxingbreaths(“breatheinthroughthenoseandbreatheslowlyoutthroughthemouth”)andtrytoimageyourselfmadeofjell-o.Byrelaxingthetension,shotscanbedonemorecomfortably.Sometimesalittledistractioncanhelprefocusthemindfromfeartosomethingelse.Watchingcartoonsorlisteningtosomefavoritemusicwithheadphonescanhelpthemindfromthinkingtoomuchabouttheshotsandaids

Sometimesapersonwithdiabetesdoesn’tgetovertheirstressaboutshots.Afewsymptomsthatmightindicatethisisgoingonare;

FpersistentlyhighHbA1c

Fachildwantingtodoalltheirownshots-particularlywhentheywanttodotheshotinaroombythemselves(someshotswillprobablybemissed)

Flackofsiterotation(hypertrophy,orhardtissueattheinjectionsite)

Fmissedinsulinshots

Fexcusesforwantingto“putoff”theshot(stalling)

Fparentalfearorworryaboutinjectionsorblooddraws

Thepsychosocialmemberoftheteamcanbeveryhelpfultochildrenorparentswithsortingoutthisproblem.Treatmentcanincludebehavioraltechniquesandpurposefuldistraction.ThelatterincludesTV,music,toys,blowingbubblesandbooks.Sometimesinjectiondeviceshelptheproblem(Inject-Ease)though

theydonot“cure”it.Behavioraltechniquesincludelearningtorelax,rewardprograms,systematicdesensitizationandbiofeedback.Asfearofshots,bloodorinjurydecreases,theHbA1cusuallyimproves.

Thefirststepinmakingshotseasierisidentifyingwhenkidsarehavingmoreanxietythantheyshould.Ifyoufeelshotshavebeentoomuchofabattlearoundyourhouselately,youmightmentionthatatyournextvisitandwe’llseehowwecanhelp.

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TakING dIaBETES TO SCHOOl CONFERENCE

— Regina Reece

heBarbaraDavis Centerfor Childhood Diabetesheld itsannual,“TakingDiabetestoSchool”conferenceonFriday,October15thattheNighthorseCampbellNativeHealthBuilding,locatedattheCUAnschutzMedicalcampus.ThisprogramwasstaffedbytheBDCPediatricClinicaswellasMichellePassamaneckofADA,KathleenPatrickofColoradoDepartmentofEducationandAmyReevesofMedtronicDiabetes.

Therewere90attendeesrangingfromclinicaidstoschoolprincipalswhoenjoyedaninformationpackeddaywheretopicsincluded:WhatisDiabetes,Psych-SocialIssues,NutritionManagement,SchoolHealthPlans,andtheImportanceofaSchoolNurse.

Therewerealsohands-onworkshopsintheafternoonthatcoveredthefollowingareas:PumpsandSensors,HowtoHandleHighandLowBloodGlucoseLevelsandtrainingonvariousbloodglucosemonitorsandonhowtousesyringesandinsulinpensonpediatricpatients.

Aspecialappreciationisexpressedtothefollowingsupporterswhomadethisprogrampossible:AbbottDiabetesCare,AmericanDiabetesAssociation,AnimasCorporation,BD,theChildren’sDiabetesFoundation,theColoradoDepartmentofEducation,TheGuildoftheChildren’sDiabetesFoundation,LillyUSA,LLC,MedtronicDiabetes,NovoNordisk,Inc.andsanofi-aventis.

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lIlly CONFERENCE

— Regina Reece

Type 1 Diabetes Experience-Based Learning Program

heBarbaraDavis Centerfor Childhood Diabetes(BDC) hostedthe“Type1DiabetesExperience-BasedLearningProgram”forLillyUSA,LLC(acompanythatdevelops,manufactures,marketsandsellspharmaceuticalandanimalhealthproducts).

ThistwodayprogramheldonOctober19-20,2010wasdesignedtoaidtheLillyteamof50individualsfromthebasicsof,“WhatisDiabetes?”tothemostcurrenttechnologyinthediabetesrealmsuchasusingContinuousGlucoseMonitoringdevices(CGMs).

COnFEREnCE DIRECTOR: GeorgeannaKlingensmith,MD,DirectorofPediatricClinicalCareandTranslationalClinical

ResearchattheBDCandtheChildren’sHospital,puttogetheranimpressiverosterwiththefollowingBDCclinicalstaff:

PHySICIAnS:H.PeterChase,MDGeorgeEisenbarth,MD,PhDRosannaFiallo-Scharer,MDRobertSlover,MD

nURSE PRACTITIOnER:StephanieKassels,DNP(c),FNP-BC,CDE

nURSES:GeorgiaKoch,RN,BSN,CDELaurelMesser,RN,MPH,CDE,SarahMorey,RN,BSNSusieOwen,RN,CDEKathySmith,RN,BSN,CDESallySullivan,RN,CDEGracielaTellez,RNLibbieTuthill,RN,BSN,CDE

SOCIAL WORKERS:LisaMeyers,LCSW,CDEDanaShepard,LCSWRitaTrujilloHughes,LCSW,CDE

DIETITIAnSLoiseGilmer,MD,RD,CDEGailSpiegel,MS,RD,CDE

Participantsalsoattendedabreakoutsessionthatprovidedtheopportunitytohavehandsonexperiencewithessentialdiabetescaretasksthatfamiliesneedtomasterinordertosafelymanagediabetesathome.Thesetasksincludedinsulininjections,bloodglucosemonitoringandrecognitionofmildandmoderatehypoglycemiaaswellasthetreatmentofseverehypoglycemiawithglucagon.

Wealsohadauniqueopportunitytopresentapatientandparentpanelsessionwherecasescenariosweregiven,aswellashaveaquestionandanswersessionduringthistime.

TheBDCislookingforwardtoofferingthisprogramwithLillyin2011.

T

Photo: © Janssen Photography

18

eareproudto announcegreat newsonthe searchforthe newDirectorofPediatricDiabetesServicesatBarbaraDavisCenterandTheChildren’sHospitalDenver.Aftermonthsofanintensivesearchprocessthatincludedseveralexcellentcandidates,thepositionwasofferedtoDr.RobertSlover,AssociateProfessorofPediatrics.Dr.SloverisexpectedtotakethenewpositiononJanuary1,2011.

RobSloverearnedhisMDdegreefromtheUniversityofUtahMedicalSchoolin1975.Hedidhispediatrictraininghere,attheFitzsimonsArmyMedicalCenterin1975-1978,andisagraduateofourPediatricEndocrinologyandDiabetesFellowshipprogram(1980-1982).RobhasbeenonthefacultyoftheSchoolofMedicine,UniversityofColorado,since1990andontheBDCfacultysince1994.Forthepastfiveyears,hehasservedastheDeputyDirectorofPediatricDiabetesServices.HisresearchinterestsincludeContinuousGlucoseMonitoring,artificialpancreas,CysticFibrosisrelateddiabetesandtransitioncare,amongmanyothers.Robisanoutstandingclinicianandeducator.

OneofthemaintasksfacingRobandallofusistofurtherstrengthenourcollaborationwithChildren’sHospital,Denver’sincreasingpatientload,bothambulatoryandinpatients,andwithincreasingcomplexityofdiabetescare.

Welookforwardtoworking

dR. SlOvER NaMEd NEw dIRECTOR OF PEdIaTRIC SERvICES

— Marian Rewers, MD, PhD, Clinical Director for Barbara Davis Center for Childhood Diabetes

W

closelywithourTCH-basedcolleaguesandwithmultiplechildren’sservicestooptimizeoureffortsforthebenefitofchildrenandyoungadultswithdiabetes.WecongratulateDr.Sloverinhisselectionforthisimportantleadershipposition.

OnbehalfoftheBarbaraDavisCenterandChildren’sDiabetesFoundation,wewouldliketothankDr.GeorgeannaKlingensmithfor17yearsofheroutstandingserviceastheDirector.GeorgeannahaschaperonedtheServicethroughchallengingtimes.First,sheledtheconsolidationofoutpatientdiabetesservicesattheBDCin

1994.Morerecently,GeorgeannahasbeeninstrumentaltoestablishingexcellentPediatricDiabetesServicesonthecampus.Theclinicvolumehasquadrupledunderherwatchandsohasthestaffandfunding.I’mhappytotellyouthatGeorgeannaisstayingattheBDCandagreedtocontinuemanyofhercurrentactivities,includingpatientcare,teaching,leadingtheT32traininggrantandworkingastheprincipalinvestigatoronseveralstudies,e.g.,PDCandExchange.

Marian Rewers, MD, PhD, Professor, Pediatrics & Preventive Medicine, Clinical Director, Barbara Davis Center

for Childhood Diabetes.

Bar

bara

Dav

is C

ente

r

Photo: © Martin Crabb

19

Barbara D

avis Center

BaRBaRa davIS CENTER aT FITzSIMONS dONOR wall

dONOR wall FORM

Name________________________________________________________

Address______________________________________________________

City_____________________________State______Zip_______________

Homephone_____________________Workphone____________________

Cellphone___________________E-mail____________________________

Amount$___________________

_____________________________________________________________

(Nameasyouwishittoappearondonorwall)

MakecheckpayabletoChildren’sDiabetesFoundationor

qVisa qMastercard qAmericanExpress

Nameoncard_________________________________________________

Card#________________________________________________________

Mailpaymentto:

Children’sDiabetesFoundation—DonorWall

777GrantSt.,Ste.302

Denver,CO80203

syourchilda patientatthe BarbaraDavis Center?Areyoua patientattheBarbaraDavisCenter?Doyouhaveaspecialinterestindiabetes?Thisisanopportunityforyou,yourfamilyandyourfriendstohaveapresenceattheCenterbypurchasingaplaceonthedonorwall,ornamingrightsonaroom—alastingsymbolofyoursupport.HelpUsCatchtheBrassRing—aCureforDiabetes.Levels1,2and3willalsobeentitledtonamingrightsonaroomattheBarbaraDavisCenter.ForinformationcallChrissyat303-863-1200.

I

FUNdING OPPORTUNITIES:

LEVEL 1 $50,000 and above

LEVEL 2 $30,000 to $49,999

LEVEL 3 $10,000 to $29,999

LEVEL 4 $1,000 to $9,999

LEVEL 5 $100 to $999

Photo: © Steve Groer Photography

20

Que

stio

ns a

nd A

nsw

ers QUESTIONS aNd

aNSwERS—H. Peter Chase, MD

What is the main cause of low-blood sugar seizures in youth and can they be prevented?

Preceding exercise isdescribedas themain recognizedcontributingfactorforseverehypoglycemiainyouth.Preventioninvolves“thinkingahead.”Peopleusinginjectionsneedtoreduceinsulindosagesbothforthetimeofexerciseandforthenight.Extrasnacksmaybeneeded.Peopleusinginsulinpumpscanusea“0”to50%temporarybasalduringtheexercise(sometimesbeginning30minutesbefore),andan80%temporarybasalratefrom9p.m.to3a.m.Theuseofacontinuousglucosemonitor(CGM)withalarmsforlowscanalsobeveryhelpfulinprevention.

My doctor has found my child to have high transglutaminase antibodies that are associated with celiac disease. Does my child need to have an intestinal biopsy before considering a gluten free diet?

— From Dr. George Eisenbarth, MD, PhD

Childrenwith type1diabetes areathigher riskforceliac disease,anillnessinwhichgluteninthedietfromanumberofsources(e.g.wheat)causesthebody’simmunesystemtoattacktheinnerwall

oftheintestine.Whenchildrenhavesevereceliacdiseaseassociatedwithweightlossanddiarrhea,avoidingglutenusuallymakesthesymptomsgoawayandallowsthechildtogrownormally.Nowadayswescreenforceliacdiseasewithasimplebloodtestforanantibodythatappearsintheblood,termedtransglutaminase.Ifhighlevelsoftheantibodyarefound,werecommendabiopsytoconfirmthediagnosis,asceliacdiseaseisalife-longdiagnosisandnosingletestisdiagnostic.Thebiopsyisusuallydonewithanesthesiasothechildisnotconsciousfortheprocedure.Atubewithacameraisswallowedandatthefirstpartofthesmallintestineseveralpiecesoftheintestinearetakenthroughtheswallowedtube,eachaboutthesizeofapenciltip.Thebiopsyisthenanalyzedbythedoctorsunderamicroscopetoconfirmadiagnosisofceliacdiseaseanddeterminetheamountofintestinaldamage,ifany.

Manychildrendonothavesymptomsofceliacdiseaseeventhoughtheyhaveantibodiesintheblood.Highlevelsofantibodiesusuallyindicatethatthereisdamagetotheintestine,andingeneralwerecommendbiopsyonlywhentheantibodylevelsarehigh,unlesstherearealsoceliacdiseasesymptoms.Inmanychildrenwithoutsymptomswithhighlevelsoftheantibodythereisseveredamagetotheintestine.Itisremarkable,butevenwithseveredamage,withaglutenfreediettheintestinecangrowbackandbenormalaslongasglutenisavoided.Ingeneralwithadiagnosisofceliacdiseasewerecommendlife-longavoidanceofgluten.Itisveryimportanttohaveafirmdiagnosisforpeoplewithsymptomsorhighlevelsofantibodies,andthustherecommendationforconfirmationthroughabiopsy.

Q:

Q:a:

a:


21

Carousel D

aysCHIllS aNd THRIllS FOR HallOwEEN

^̂ ^ reativejuices wereflowing atTheGuild’s 27thAnnual HalloweenPartyforChildrenwithdiabetes.TheextravaganzatookplaceintheGreenCenteratTheSchoolofMineswiththehelpofthePhiGammaDeltaFraternity.Witches,Pirates,andBuzzAldrinhimselfwereseendecoratingpumpkinsdonatedbyGuildMembersRobertandJudyVillano.Thereweregamesandprizesgaloreaswellasgoodiebagsfilledwithtoysandalternativesnacks.

Theeventwasahugesuccess!Nooneleftthepartyhungry;thegreatpeopleatPepsiBottlingGroupdonatedDietSodaandBottledWaterandPizzawasservedbyChildren’sDiabetesFoundationVolunteers.FacePaintingandBalloonanimalskepteveryoneentertainedwhilespookymusicandscarycostumeskepteveryoneontheirtoes.PhiGammaDeltaFraternitywassuchahugesupport,supervisinggamesandputtingsmilesonthechildren’sfaces.BigthanksgoesouttoJudyMcNeil,theChairmanforTheGuild,forallofherhardworkandpreparationforthisevent.Allofthevolunteersaregreatlyappreciated;withoutthem,manychildrenwouldmissthesefunHalloweenmemories.

C

22

BOOk ORdER FORM Name ____________________________________________________________________________________

Address __________________________________________________________________________________

City/State/Zip _____________________________________________________________________________

Phone(Day)___________________Phone(Eve)______________________E-mail___________________

Understanding Diabetes 11th Edition$25percopy Quantity______

Managing and Preventing Diabetic Hypoglycemia(Video)$20percopy Quantity______

Understanding Insulin Pumps & Continuous Glucose Monitors2ndEdition$15percopy Quantity______

A First Book for Understanding Diabetes(English)$10percopy Quantity______

Un Primer Libro Para Entender La Diabetes(Spanish)$10percopy Quantity______

All orders must be paid in full before delivery, including $3.00perorderforshippingandhandling.Allowonetothreeweeksfordelivery

Makecheckspayableto:Children’sDiabetesFoundationAmerican Express, Visa, and MasterCardaccepted.

Canadian and Foreign Purchasers:PleaseincludesufficientfundstoequalU.S.currencyexchangeratesandinternationalpostage.

For additional information call 303-863-1200 or 800-695-2873 or visit www.ChildrensDiabetesFoundation.org

Mailingaddress: Children’sDiabetesFoundation 777GrantStreet,Suite302 Denver,CO80203

ThePinkPanther™&©1964-2010Metro-Goldwyn-MayerStudiosInc.

AllRightsReserved

Foun

datio

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ews

For additional copies of this publication contact:

Children’s Diabetes Foundation777 Grant Street, Suite 302

Denver, CO 80203Phone: 303-863-1200 or 800-695-2873

Fax: 303-863-1122www.ChildrensDiabetesFoundation.org

The Pink Panther™ & ©1964-2010Metro-Goldwyn-Mayer Studios Inc.

All Rights Reserved

www.pinkpanther.com

UN

DER

STAN

DIN

G IN

SULIN

PU

MP

S AN

D C

ON

TIN

UO

US G

LUC

OSE M

ON

ITO

RS 2

nd

Edition

by H. Peter Chase, MD & Laurel Messer, RN, MPH, CDE

•

2nd Edition

12:4

3

23

NOw avaIlaBlE2nD EDITIOn – UnDERSTAnDInG InSULIn

PUMPS AnD COnTInUOUS GLUCOSE MOnITORS (CGMS)

—H. Peter Chase, MD and Laurel Messer, RN, MPH, CDE

THE OnLy BOOK AVAILABLE FOR PATIEnTS WITH DIABETES COVERnG BOTH InSULIn

PUMPS AnD COnTInUOUS GLUCOSE MOnITORS (CGMs)

ThefieldofinsulinpumpsandCGMsismovingsorapidlythattheneedforasecondeditionofthisbookwasimperative.All

chaptersarenowrevised.However,someoftheimportantchangesarelistedbelow:

•AnattempthasbeenmadetointegratetheteachingaboutinsulinpumpsandCGMs–astheycomplementeachothergreatly.Togethertheyarethetwomajortechnologiesbeingusedfordiabetesmanagementtoday!

•Thechaptersinbasalrates(Chapter5)andinsulinboluses(Chapter6)areupdatedwithlatestinformation–includingafigurefromaresearcharticlepublishedin2010showingtheimportanceofgivingboluses20minutespriortomeals.

•Theadvantagesofaninsulinpumpoverinsulininjectionsinthepreventionofhypoglycemiaduringexercisehavereceivedanewemphasis.

•Thechapter(Chapter14)onPsychologicalAspectsoffersnewwaystodealwithpumpandCGMissues.

•TheoverviewonCGMs(Chapter16)dealswithimportantissuesincludingpracticalmethodsofCGM(orinsulinpump)adhesiveissues.

•Twobrand-newchapterswerecreatedbecausereadersofthefirsteditionstatedtheywantedmoreinformationonhowtoadjustinsulinlevelsbasedon“Real-Time”CGMreadings(Chapter18)andon“Retrospective”CGMreadings(Chapter19).Thesetwonewchaptersprovidetheinformationtohelpanyperson/familymaketheneededinsulinadjustmentstoattainthemostoptimalglucosecontrolcurrentlypossible.

•Theresearchchapter(Chapter20)includesinformationrelatingtorecentstudiesofthe“Bionic”pancreas(usinganinsulinpumpandaCGM)andwherecurrentstudiesareleadingfuturediabetescare.

Theneweditionisavailablebycalling303-863-1200or800-695-2873oratwww.ChildrensDiabetesFoundation.org

Foundation New

s

For additional copies of this publication contact:

Children’s Diabetes Foundation777 Grant Street, Suite 302

Denver, CO 80203Phone: 303-863-1200 or 800-695-2873

Fax: 303-863-1122www.ChildrensDiabetesFoundation.org

The Pink Panther™ & ©1964-2010Metro-Goldwyn-Mayer Studios Inc.

All Rights Reserved

www.pinkpanther.com

UN

DER

STAN

DIN

G IN

SULIN

PU

MP

S AN

D C

ON

TIN

UO

US G

LUC

OSE M

ON

ITO

RS 2

nd

Edition

by H. Peter Chase, MD & Laurel Messer, RN, MPH, CDE

•

2nd Edition

12:4

3

ThePinkPanther™&©1964-2010Metro-Goldwyn-MayerStudiosInc.

AllRightsReserved

24

Your support gives hope for their future.

With love and appreciation, Barbara Davis

Kendall (top photo in pink sweater) was diagnosed with type 1 diabetes, a week after her fourth birthday, in December 2009.

ONE IN THREE BaBIES BORN TOday wIll HavE dIaBETES IN THEIR lIFETIME.

Photo from 2006 Carousel Ball Journal

Photo: © kentmeireisphotography.com


25

verydayin America35 childrenare diagnosedwith type1diabetes--morethanonechildeveryhour.Ofthe24millionAmericansnowafflictedwithdiabetes,twomillionhavethemostsevereform,type1,andneedinsulintosurvive.Butinsulinisnotacure.Everyonewithdiabetesneedsourhelptoendtheepidemic,andeverydonationcounts.

TheBarbaraDavisCenterforChildhoodDiabetes(BDC)istheleadingworldwidecenter

Foundation New

sREaCHING FOR THE BRaSS RING a CaMPaIGN TO CURE dIaBETES

Eforchildrenandadultswithtype1diabetes.YourdonationstoourannualREACHINGFORTHEBRASSRING:ACAMPAIGNFORTHECUREsupportChildren’sDiabetesFoundation’scommitmenttogiveallBDCpatientsthesamehighqualitycare.Nochildisturnedaway.Insulin,suppliesandclinicvisitscancostupto$800ormoreamonth--afinancialburdenforanyfamily,impossiblefortheuninsuredandimpoverished.Throughyourgiftsweprovidetreatmentandsuppliestonearly30%oftheBDC’spatientswhootherwisecouldnotaffordit.

TheBDC’sworld-renownedclinicalandresearchprogramsincludestemcellandisletcelltransplantresearch,andtestingforgeneticandimmunologicriskofdiabetes.Trialscontinueonavarietyofagents,includinganewvaccinetrialtopreventdiabetesinthosechildrenmostgeneticallyat-risk.

Please,helpuscatchthebrassringbysupportingourCAMPAIGNFORTHECURE.Whenyouhelpchildrenwithdiabetesyouempowerthemtocreateabetterfutureforall.

Countmeinforadonationof$____________________

Donate online at ChildrensDiabetesFoundation.org/C2C❏ EnclosedismycheckpayabletoCDF.

Mycontributioncanbematchedbymycompany___________________________________________________ (nameofcompany)

Chargemycreditcard:❏ Visa❏ MasterCard❏ AmericanExpress

Creditcard#__________________________________________________Expirationdate__________________

Nameoncard_________________________________________________________________________________

❏ IhaveincludedCDFinmyWill.

Yourgiftistaxdeductible.Taxexempt#:84-0745008

HELP US GO GREEn!

Registeronlineatwww.children’sdiabetesfoundation.organdqualifytoWIn An APPLE IPAD!

Weneedyoure-mailaddresstosende-blastswiththelatestnewsonBDCclinicalcareandresearch,announcementsofouractivities,andtheChildren’sDiabetesFoundation’snewsletter,NEWSNOTES.Helpsaveourplanetwhilewehelpchildrenwithdiabetes!

Adrawingwillbemadeofalle-mailaddressesreceivedthroughJanuary2011(whetheronlineorthroughthemail).ThewinnerwillbeannouncedonourwebsiteinFebruary2011.your e-mail address will never be shared with any individual or organization.

Name/Contact_________________________________________________________________________________

E-mailaddress________________________________________________________________________________

Address ______________________________________________________________________________________

City______________________________________________________State__________Zip_________________

Home#_________________________Office#________________________Fax#________________________

❏ PleaseremovemefromallChildren’sDiabetesFoundationmailinglists.

26

Foun

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ews MaNaGEMENT

OF dIaBETES IN yOUTH

JULy 17-20, 2010KEySTOnE RESORT AnD COnFEREnCE CEnTER

orethan400 healthcare providersfrom allover thecountryattendedthe11thbiennialconference“ManagementofDiabetesinYouth”wheretheyreceivedthelatestinformationontheintensivemanagementoftype1andtype2diabetesinchildrenandadults.

Conferenceco-directorsMarianRewersMD,PhD,ClinicalDirectoroftheBarbaraDavisCenterforChildhoodDiabetesandGeorgeannaKlingensmith,ChiefofthePediatricClinicattheBDCputtogetheranoutstandingrosterofrenowneddiabeteseducators,whoalongwithBDChealthcarestaff,providedparticipantswithessentialinformationfacingtoday’shealthcareproviders.

Industrysponsoreddinnersfeatured:LillyUSA,LLC(GuestSpeaker:Dr.HenryRodriguez),NovoNordisk(GuestSpeaker:Dr.AsheeshDewan)andMedtronicDiabetes(GuestSpeaker:Dr.FranKaufman).

SpecialthankstothefollowingGuestSpeakersandSponsors/Exhibitorsforparticipatinginandprovidingfinancialassistanceforthisyear’sconference:

GUEST SPEAKERS:

H. Peter Chase, MD,ProfessorofPediatrics,BarbaraDavisCenterforChildhoodDiabetes,ProfessorofPediatrics,UniversityofColoradoDenver,Aurora,CO.

Ron Gill, PhD,ProfessorandResearchDirectoroftheTransplantationInstituteColorado,Aurora,CO.

Peter Gottlieb, MD,AssociateProfessorofPediatricsattheBarbaraDavisCenterforChildhoodDiabetes,Aurora,CO

Irl Hirsch, MD,ProfessorofMedicine,UniversityofWashington,SchoolofMedicine,Seattle,WA.

Lois Jovanovic, MD,DirectoroftheSamsunResearchInstitute,SantaBarbara,CA.

David M. Kendall, MD,ChiefScientific&MedicalOfficer,AmericanDiabetesAssociation,Alexandria,VA.

Aaron Kowalski, PhD, ProgramManager,MetabolicProtocol/ResearchDirector,ArtificialPancreasProject,JuvenileDiabetesResearchFoundation,NewYork,NY.

Johnny L. Ludvigsson, MD, PhD, ProfessorofPediatrics,HeadPhysician,DivisionofPediatrics,Linkoping,UniversityHospital,Sweden.

Henry Rodriguez, MD,AssociateProfessorofPediatrics,JamesWhitcombRileyHospitalforChildren,Indianapolis,IN.

Gary Scheiner, MS, CDE, IntegratedDiabetesServices,Wynnewood,PA.

Grace Shih, RD,PackardChildren’sHospital,StanfordMedicalCenter,PaloAlto,CA.

Jay S. Skyler, MD,ProfessorofMedicine,Pediatrics&Psychology,AssociateDirector,DiabetesResearchInstitute,UniversityofMiami,MillerSchoolofMedicine,Miami,FL.

M

Photo: © Vail Resorts

27

William V. Tamborlane, MD, ProfessorandChiefofPediatricEndocrinology,YaleSchoolofMedicine,NewHaven,CT.

William E. Winter, MD,ProfessorofPathologyandPediatrics,UniversityofFlorida,Gainesville,FL.

Phil Zeitler, MD, PhD,ProfessorofPediatricsandClinicalScience,UniversityofColoradoDenver,MedicalDirector,Children’sHospitalClinicalTranslationalResearchCenter,ColoradoClinicalTranslationalScienceInstitute,Aurora,CO.

PLATInUM

sanofi-aventisU.S.Inc.

LillyUSA,LLC

BayerHealthCareDiabetesCare

GOLD

MedtronicDiabetes

NovoNordisk,Inc.

SILVER

AbbottDiabetesCare,Inc.

BDMedical/DiabetesCare

BRASS

AnimasCorporation

AthenaDiagnostics,Inc.

CumberlandHospitalforChildrenandAdolescents

DiamydMedical

InsuletCorporation

LifeScan,Inc.

RocheDiagnostics

SavE THE daTE!

kEySTONE CONFERENCE 4TH BIENNIal

“PRaCTICal wayS TO aCHIEvE TaRGETS IN dIaBETES CaRE”

Friday, July 15, 2011 thru Saturday July 17, 2011

Designed to help health care providers caring for adolescents and adults with diabetes,

Check the Children’s Diabetes and Barbara Davis Center web sites

in January 2011 for more information.

www.ChildrensDiabetesFoundation.orgwww.BarbaraDavisCenter.org

-

Foundation New

sPhoto: © Vail Resorts

28

Foun

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inetyavidgolfers andahandfulof dedicated volunteers assembledatthecrackofdawnatSignatureAviationonNovember4thtoflyawaytoLasVegastoPlayfortheCureattheMcDonaldAutomotiveCarouselClassictobenefittheChildren’sDiabetesFoundation.AcharterFrontierjetflewthefestivegrouptoTheWynnwheretheyplayedonthefabulousWynncourse,andstayedovernighttoenjoytheVegasscenewhilenetting$223,000tohelpfundresearchattheBarbaraDavisCenterforChildhoodDiabetes.LedbyMichaelMcDonaldandDanFullerwhoshareapersonalinterestineradicatingdiabetes,thiseventfollowedtheHealthOneCarouselClassicheldinJuneattheCherryCreekCountryClub.Thecombinedeventsgrossedanastounding$386,000.Wewouldliketoofficiallythankourfly-away

NsponsorsincludingMcDonaldAutomotive,LocktonCompanies,AffinityVideo,BercoResourcesLLCandInterstateRestorations.WewouldalsoliketothankoursupportcrewatFrontierAirlines,TheWynnHotel,AWG,WhatzhotnowCatering,everyoneattheSignatureHangerandallofourgolfers.Itwasasuccessfultournamentanditwouldn’thavebeenpossiblewithoutyou!ThiswasTheCarouselClassic’sfirstyearfortheChildren’sDiabetesFoundation.Plansarealreadyunderwayfor2011withtheJune29theventatSanctuaryGolfCourseandthefly-awayagainatTheWynnearlynextNovember.RavereviewsarestillcominginproclaimingTheCarouselClassicasolidgoldwinner!

Forfurtherinformationortoregisterforthe2011eventswhicharesuretosellout,contactAmyCockerhamat303-863-1200.

SavE THE daTE!

WHAT:High Hopes Carousel Ball

October 1, 2011

WHAT: 2011 Carousel Classic Sanctuary Golf Course

June 29th, 2011

WHAT: The Guild’s High Hopes

Golf Tournament Glenmoor Country Club

July 18th, 2011

WHAT: Keystone Conference 4th

biennial “Practical Ways to Achieve Targets in

Diabetes Care” July 15-17th, 2011

MCdONald aUTOMOTIvE CaROUSEl ClaSSIC a wyNN/wIN

29

BaUBlES, BaNGlES aNd BEadSIf a Bead or a Pearl, a piece of Gold or Silver

Would help toward a cure…

Would you give from your jewelry drawer

To raise money to find a cure.

We have started Jewels for Hope To help save our true ‘Jewels’

Children who live with Diabetes

We are asking you to give a piece of jewelry

Real or costume, it does not matter,

Someone else will treasure it knowing

It will help us toward a cure.

Now won’t you reach into your Jewelry Drawer?

— by Gretchen Pope

To donate contact Susie Hummell at 303-863-1200.

2011 GUIld

OFFICERS2010 GUILD OFFICERS

President:JudyMcNeil

President-Elect: GinaAbou-Jaoude

Recording Secretary: JenniferBarrow

Treasure: AnnieCotton

Treasurer-Elect: GleneenBrienza

Corresponding Secretary: ShelleyLucas

Immediate Past President: SharonKamen

Advisors:SandyBurfittKathyCrapoMartyJensenGailJohnson

CHaRlOTTE TUCkER SCHOlaRSHIP OPPORTUNITIES FOR 2011-2012

heGuildofthe Children’s Diabetes Foundation isalwaysproudtoawardscholarshipstohighschoolseniorsandcollegestudentswhoarecurrentpatientsattheBarbaraDavisCenter.ThescholarshipprogramwasestablishedinmemoryofpastGuildPresident,CharlotteTucker,whoencouragedyoungpeoplefromtheBarbaraDavisCentertofollowhighercareerandeducationalpursuits.

Applicationsfor2011-2012willbeavailableinFebruary2011. PatientswhoarecollegeortradeschoolboundwillbenotifiedregardingapplicationsinFebruary2011.Ifyoudon’treceiveinformationorhavequestions,pleasecallSusieHummellattheCDFofficeafterFebruary14th,2010at303-628-5109or800-695-2873.

T

GUIld MISSION STaTEMENT

TheGuildoftheChildren’sDiabetes

FoundationatDenverraisesfundsforclinical

andresearchprogramsfortheBarbaraDavis

CenterforChildhoodDiabetes.TheGuild

promotesdiabetesawarenessandeducation;

assistsfamiliesinneed;providescontinuing

educationscholarshipsandsponsorssocial

activitiesforchildrenandtheirfamilies.

å

aNNUal MEETING

Monday,January10,2011

DenverCountryClub

1700East1stAvenue

Denver,CO

COFFEE9:30a.m.

MEETING10:00a.m.

Brunchwillbeserved

followingmeetingand

program.

Reservation:$35.00

Pleasemakeyourreservationforthebrunchbysendingacheckto:

Children’sDiabetesFoundationAttn:SusieHummell

777GrantSt.,Ste.302Denver,CO80203

Topaybycreditcard,pleasecallSusieat303-628-5109ore-mailat

[email protected]

Guild G

uide

30

Win

ner’s

Circ

le

Harrison receives care at the Barbara Davis Center for Childhood Diabetes.

This was his prayer at the Carousel of Hope, October 23, 2010.

Dear God,Tonight I have a special prayer for all of the children

suffering with type 1 diabetes. I pray that you keep us brave in our fight, please bless

our parents with patience, and help the doctors working to find a cure.

I thank you for Barbara Davis and all of the loving people here tonight supporting kids like me.

In your name we pray, Amen.Harrison Fuller, Age 7

A PrayerkIdS HElPING kIdS hankyouAspen Academystudents, facultyand HarrisonFullerfor raising$353.00forChildren’sDiabetesFoundationatyourDressDownFundraiser.YourfundswillhelptofurthercareandresearchprogramsattheBarbaraDavisCenterforChildhoodDiabeteswhichcaresfor5,000childrenandyoungadults.

Wearehonoredtohavethestudents,facultyandfamiliesofAspenAcademyjoinusinthefightagainstdiabetes.Weareespeciallyproudtoseekidshelpingkids.Yourgifthasaveryspecialmeaningtoourorganizationandchildrenwithdiabetes.Congratulationsonyourverysuccessfulfundraiser!

ThankyouHarrisonfordoingsuchagreatjobspeakingonbehalfofallofkidsattheBarbaraDavisCenterattheCarouselofHope.Wearesoproudofyou!

TPhoto: © kentmeireisphotography.com

31

Cooks C

ornerCHOCOlaTy PUMPkIN BaRS— Makes 30 bars

InGREDIEnTS1cupall-purposeflour 1cupwholewheatflour 1cuppecans,veryfinelychopped3/4cupgranulatedsugar 2teaspoonsbakingpowder 1teaspoongroundcinnamon1/2teaspoonbakingsoda 1/2teaspoonsalt 4largeeggs,beaten115-ouncecan100%purepumpkin 1/2cupcanolaoil 1/4cup1%low-fatmilk1/2cupminisemi-sweetchocolatechips

DIRECTIOnSPreheattheovento350°F.Lightlyoilorcoata15x10x1-inchrimmedbakingorjellyrollpanwithnonstickcookingsprayandsetaside.

Whisktogethertheall-purposeflour,wholewheatflour,pecans,sugar,bakingpowder,cinnamon,bakingsoda,andsaltinalargebowluntilwellcombined.

Inaseparatebowl,whisktheeggs,pumpkin,oil,andmilkuntilwellblended.Pourtheliquidingredientsoverthedryingredientsandstiruntiljustcombined.Stirinthechocolatechips.

Spreadthebatterevenlyinthepreparedpanandbakefor25minutes,oruntilawoodentoothpickinsertedinthecentercomesoutclean.Transferthepantoawirerackandcoolfor10minutesbeforeslicingintothirty,2x2½-inchbars.

Tip: For maximum freshness, store leftovers in a plastic container or zip-top bag in the refrigerator.

nUTRITIOn InFORMATIOn PER SERVInG (1 BAR):140calories,6gfat(1gsaturated,0.4gomega-3),95mgsodium,16gcarbohydrate,2gfiber,2gprotein,45%vitaminA

aPPlE BlUEBERRy walNUT CRISP— Makes 6 Servings

InGREDIEnTS3largeRedorGoldenDeliciousapples(about2pounds),unpeeledandcutinto1/2-inchpieces(about4cups)2tablespoonsbrownsugar 2tablespoonswholewheatflour1teaspoonvanillaextract 1/2teaspoongroundcinnamon1cupfreshorfrozenblueberries 1/2cupwalnuts,veryfinelychopped1/2cupold-fashionedorquick-cookingoats 2tablespoonsbrownsugar2tablespoonswholewheatflour 2tablespoonsgroundflaxseedorwheatgerm1/2teaspoongroundcinnamon 2tablespoonscanolaoil1/8teaspoonsalt

DIRECTIOnSPreheattheovento400°F.Placetheapples,brownsugar,flour,vanilla,andcinnamoninalargebowlandtosstocoat.Gentlystirintheblueberries.

Placetheapplemixtureinan8x8-inchbakingpanordishandsetaside.

Tomakethetopping,placethewalnuts,oats,brownsugar,flour,flaxseed,cinnamon,andsaltinamediumbowlandstirtocombine.Addtheoilandstiruntiltheoatmixtureiswellcoated.Spreadthetoppingevenlyoverthefruitmixture.

Bake40to45minutes,oruntilthefruitistenderandthetoppingisgoldenbrown(coverwithfoilabouthalfwaythroughifthetoppingbrownstooquickly).

Tip: Top each serving with low-fat vanilla frozen yogurt or a dollop of light whipped cream.

NUTRITIOn InFORMATIOn PER SERVInG: 260calories,13gfat,(1gsaturated,1.8gomega-3),55mgsodium,34gcarbohydrate,5gfiber,4gprotein,10%vitaminC

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SCOOP ON SwEETENERS?

— Gail Spiegel MS RD CDE

hefollowingisan updateonthe sweetenersthat arecurrently approvedbythefoodandDrugAdministration(FDA)andavailableonthemarket.TheBarbaraDavisCenterdoesnotendorseorcondemnanycertainproduct.

Sweetenerscanbedividedintotwogroupsbasedonthecaloriestheyprovide.Thesetwogroupsarenutritive(containcalories)andnon-nutritivesweeteners(donotcontaincalories).

nUTRITIVE SWEETEnERS

Nutritivesweetenersprovidecaloriesandcarbohydratesandincludetwotypesofsweetenersthatarecommonlyused:sugars,sugaralcohols.

SUGARS

Sugarsweetenersincludesucrose(tablesugar),fructose,honey,highfructosecornsyrupaswellasothers.Sucroseandfructosearetheprimarysugarsweetenersthatoccurnaturallyinthefoodsupplyorareaddedassugarsincornsweetenersandsyrups.Sugarsweetenersprovide16caloriesand4gramsofcarbohydrateperteaspoon.

Agavenectar,whichhasrecentlybecomepopular,isasyrupthatisrefinedfromacactus-likeplant.Agavenectarismadeoffructoseandglucose.Agaveis140–160timessweeterthansugar.Oneteaspoonprovides20caloriesand5gramsofcarbohydrate.

SUGAR ALCOHOLS

Sugaralcoholsincludesorbitol,mannitol,xylitol,erythritol,isomaltandhydrogenatedstarchhydrolysatesaswellasothers.Mostsugaralcoholsprovideapproximately8caloriesand2gramsofcarbohydratesperteaspoon.Sugaralcoholsareabsorbedmoreslowlythansugarandeatinganexcessiveamountcancausediarrhea.XylitolisfoundinasweetenernamedIdealSweetener.Sugaralcoholsarefoundinsuchproductsassugarfreecandies,chewinggum,andbakedgoodssuchascookies.Despitebeinglabeled“sugarfree”theseproductsstillcontaincarbohydratesandwillcauseariseinbloodsugars.Erythritolismuchlowerincaloriesandcarbohydratesthantheothersandmaynotcauseariseinbloodsugars.Besuretocheckthenutritionfactsonthelabeltodeterminetotalcarbohydratecontent.

nOn-nUTRITIVE SWEETEnERS

Non-nutritivesweetenersdonotprovideanycaloriesorcarbohydrates.Therearecurrentlyfivenon-nutritive,artificialsweetenersapprovedbytheFDA.Theyaresaccharin,acesulfame-K,aspartame,sucraloseandneotame.Inaddition,Stevia,anaturalsweetenerdoesnotprovidecaloriesorcarbohydrates.

SACCHARIn

Saccharinis200-700timessweeterthansugar.Itprovidesnocaloriesorcarbohydratesandisnotmetabolizedbyourbodies.Itisapprovedforusein100countries,buthasbeencontroversialhereintheUnitedStates.Questionsaboutsaccharin’ssafetyfirstbeganin1977whenstudiessuggesteditcausedbladdertumorsinrats.Saccharinusedtocarryawarningonthelabel,butin2000the

T

NationalInstitutesofHealthremovedsaccharinfromthelistofcarcinogensandCongressremovedtherequirementforwarningnotices.Studiesofhighusersdonotsupportanassociationbetweensaccharinandcancer.SaccharincanbefoundinSweet’NLow®,SweetTwin®andothertabletopsweetenersaswellasfountaindrinks.Theamountofsaccharinineachproductislimitedandmustbeprintedonthelabel.

ACESULFAME-K (ACE-K)

Ace-Kis200timessweeterthansugar.Thissweetenerisnotmetabolizedbythebodyeitherandthereforeprovidesnocaloriesorcarbohydrates.IthasbeenapprovedbytheFDAsince1988.Itisapprovedforuseasageneral-purposesweetenerandisusedinmorethan80countries.Ace-Kdoesnotbreakdownwhenheatedandcanbeusedincookingandbaking.Itiscurrentlyusedinsugarfreeicecreamsandmanysugarfreeordietbeverages,oftentimesincombinationwithsucraloseoraspartame.

ASPARTAME

Aspartameisalso200timessweeterthansugar.Aspartameisbrokendownintoasparticacid,methanol,andphenylalaninebythedigestiveprocess.Theaminoacidsphenylalanineandasparticacidaremetabolizedtoprovidefourcaloriespergram.Becausethissweetenerisveryintenseandweuseitinsuchsmallamounts,itprovidesnocalories.AspartamehasbeenapprovedbytheFDAsince1981.Ithasbeendeemedsafebymajorhealthgroupsandagenciesinover90countries,includingtheWorldHealthOrganizationandtheAmericanMedicalAssociation.Itiscurrentlyapprovedforuseasageneral-purposesweetenerinallfoodsandbeverages.It

33

Nutrition N

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breaksdownwhenheatedanddoesnotworkwellincookingandbaking.Thissweetenerisinmanyproducts.Somecommonlyusedproductsthatcontainaspartameareasfollows:Equal,NutraSweet,NatraTaste,dietsodas,sugarfreeJELL-O,lightyogurts,powderedsoftdrinks,sugarfreeicecream.

Aspartamehascausedthemostcontroversyandappearstoreceivemoremediaattentionaboutitssafetythananyothersweetener.StudieshavenotfoundanylinkbetweenaspartameanddiseaseslikeAlzheimer’sormultiplesclerosis.Researchhasnotfoundthataspartameleadstoanincreasedriskofcancereither.Theonlynegativeeffectsthataspartamehasbeenshowntocauseinafewsmallresearchstudiesisworseningmigrainesforsomepatients.

SUCRALOSE

SucralosewasapprovedbytheFDAinApril1998foruseasatabletopsweetenerandindesserts,candiesandnonalcoholicbeverages.Sucraloseis600timessweeterthansugarandprovidesnocaloriesorcarbohydrates.Itismadefromsucrose,butisalteredsothatitismuchsweeterthansugarandisnotabsorbedbythebody.Itdoesnotbreakdownwhenheatedandcanbeusedforcookingandbaking.Sucralosecancurrentlybefoundinmanydietorsugarfreedrinks,sugarfreeicecreamandotherproducts.ItismarketedunderthetradenamesSplenda®andNevella®.Nevellaissoldinregularandprobioticversions.

nEOTAME

ThissweetenerwasapprovedbytheFDAasageneralpurposesweetenerin2002.Neotameisveryintense,40timessweeter

thanaspartameand7,000-13,000timessweeterthansugar.Itcanbeusedinbakingandcooking.Asofthewritingofthisreview,neotamewasnotfoundinanyproductsonthemarket.

STEVIA

ThisisanaturalsweetenerfromthesteviarebaudianaplantfoundinSouthAmerica.Steviarebaudianaisanherbthatis300timessweeterthansugar.Steviacontainsnocaloriesorcarbohydratesanddoesnotaffectbloodglucose.SteviahasbeensoldintheUSinthesupplementaisleformanyyears,butin2008,theFDArecognizedapartofthesteviaplant,knownasRebianaorRebA,assafeforuseinfoodproducts.Youcanbuysteviaingranularandliquidformsfromgroceryandhealthfoodstoresforuseindrinks,cookingandbaking.BrandnamesforsteviaincludeTruvia™andPureVia™.Truvia™contains3gramsofcarbohydratesperpacket,

butthecarbohydratesarenotdigestedorabsorbedbythebodyaccordingtothecompanysotheydonotaffectbloodsugar.Purevia™contains2gramsoftotalcarbohydrateperpacket.SunCrystals™isalowsugarsweetenerthatispartsteviaandpartsucrose(tablesugar).

Today,therearemorealternativesthaneverforpeoplewithdiabetes.Foodmanufacturersareusingnewsweetenersandcombiningsweetenerstoimprovethetasteandmouthfeelofsugar-freeandlow-sugarfoodsandbeverages.Plus,sucroseisnolongerrestrictedfromthedietandcanbeincludedwithinthecontextofahealthydiet.Forthosewhocountcarbohydrates,foodscontainingsugarcanbesubstitutedforothercarbohydratesinthemealplanorextrainsulincanbegiven.Whenitcomestosweeteners,eachfamilyneedstodecidewhatworksbestforthem.


34

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ews wHaT’S CONSIdEREd SaFE?

Sugar Substitute Recommended or Acceptable Product

Daily Intake (ADI)* equivalents

Saccharin 5mg/kg**bodyweight 3packetsof For23kg(50lb.)child Sweet‘NLow

Aspartame ADI=50mg/kgofbodyweight 33packetsof For23kg(50lb.)child Equalor 5cansofdietsoda

Acesulfame-K ADI=15mg/kgofbodyweight 8packets For23kg(50lb.)child ofSweetOne

Sucralose ADI=5mg/kgofbodyweight 9packetsofSplenda For23kg(50lb.)child 1.5cansofdietsoda *AcceptableDailyIntakeisdefinedastheamountatwhichthereisnoadverseeffectandareasonablecertaintythatnoharmwillcomefromuse.Itisanamountthatyoucanconsumefortherestofyourlifewithnoconcernaboutsafety.ADIissetbytheFDAandtheJointExpertCommitteeofFoodAdditionsoftheUnitedNationsFoodandAgriculturalOrganizationandWorldHealthOrganization.

**1kilogram=2.2pounds

REFEREnCESPositionofTheAmericanDieteticAssociation:Useofnutritiveandnonnutritivesweeteners,JournaloftheAmericanDieteticAssociation2004;104:255-275.

Porro,J.Sugar’sSweetStand-Ins,DiabetesInterview,Sept.1998,74:18-21.

Schardt,David.SweetNothings:notallsweetenersareequal.NutritionActionHealthletter,May2004.

0Future Newsnotes will be published online at

www.childrensdiabetesfoundation.org.

Remember to register online by January 31, 2011 to qualify to win an I-Pad.

r

35

ExECUTIVE BOARD:

Mrs.BarbaraDavis,Chairman

RichardS.Abrams,M.D.

JulesAmer,M.D.HonoraryLifetimeMember

Mr.PeterCulshaw

StephenDaniels,M.D.,Ph.D.ChairmanofPediatrics,TheChildren’sHospital,Denver

Ms.DanaDavis

Mrs.NancyDavisRickel

StevenFarber,Esq.

RichardF.Hamman,M.D.,DrPHUniversityofColoradoDenverSchoolofMedicineDean,ColoradoSchoolofPublicHealth

Mrs.ArleneHirschfeld

Mrs.DeidreHunter

Mr.ShawnHunter

M.DouglasJones,Jr.,M.D.

RichardD.Krugman,M.D.Dean,SchoolofMedicine,UniversityofColoradoDenver

StacyMendelsonRobinson

Ex-officioMember:GeorgeS.Eisenbarth,M.D.,Ph.D.ExecutiveDirector,BarbaraDavisCenterforChildhoodDiabetes,UniversityofColoradoDenver;ProfessorofPediatricsandMedicine,UniversityofColoradoSchoolofMedicine

SCIEnTIFIC ADVISORy BOARD:

RichardS.Abrams,M.D.AssociateClinicalProfessorofMedicine,UniversityofColoradoSchoolofMedicine;RoseMedicalCenter,Denver

JulesAmer,M.D.ClinicalProfessorofPediatrics,UniversityofColoradoSchoolofMedicine;Partner,Children¹sMedicalCenter,Denver

M.DouglasJones,Jr.,M.D.Professor,DepartmentofPediatrics,UniversityofColoradoSchoolofMedicine;SectionofNeonatology,TheChildren¹sHospital,Denvereeeeeeeeeeee

NEWSNOTESispublishedtwiceyearlybytheChildren’sDiabetesFoundationatDenver.Wewelcomeyourcomments.

IfyouwouldliketosubmitanarticleoralettertoNewsnotessendinformationto:

Children’sDiabetesFoundationatDenver777GrantStreet,Suite302Denver,CO80203

CindyKalkofenGraphic Designer

KatieHicksChristineLernerEditors

Know the symptoms ofChildhood Diabetes: • Loss of weight • Extreme thirst • Excessive irritability • Frequent urination • Bedwetting (previously controlled)

Printed on recycled paper

A child reaching for the brass ring on a carousel is symbolic of the most important goal of the Children’s Diabetes Foundation — The cure.Yourcontributiononbehalfofalovedonewillmakeadifference.ItwillsupporttreatmentprogramstoassistchildrenwithdiabetesinleadinghealthierlivesanditwillfundresearchtohelpCDF“CatchtheBrassRing”byfindingacure.

Markananniversary,birthday,specialoccasion;expressappreciationormakeamemorialtributeinhonorofsomeonespecialwithacontribution—foranyamount—totheChildren’sDiabetesFoundationatDenver.Wenowacceptgiftsonline.

Donationsaretaxdeductible.TaxID#84-0745008

The Brass Ring FundRemember a loved one –– Help CDF “Catch the Brass Ring”

Enclosedismycontributionof$_______________________Inmemoryof_______________________________________Orinhonorof_______________________________________Occasion__________________________________________Pleasesendacknowledgementsto:(Amountofgiftwillnotbementioned)

Name_____________________________________________Address___________________________________________City__________________State________Zip___________FromName_____________________________________________Address___________________________________________City__________________State________Zip___________

Children’s Diabetes Foundation at Denver, Colorado777GrantStreet,Suite302,Denver,CO80203

303-863-1200,800-695-2873,www.ChildrensDiabetesFoundation.org

BrianKotzin,M.D.VicePresident,GlobalClinicalDevelopment,Amgen,Inc.ThousandOaks,California

AkéLernmark,M.D.,Ph.D.RobertH.WilliamProfessor,DepartmentofMedicine,UniversityofWashingtonSchoolofMedicine,Seattle

AliNaji,M.D.,Ph.D.J.WilliamWhiteProfessorofSurgery,HospitalofUniversityofPennsylvania,Philadelphia

GeraldNepom,M.D.,Ph.D.ScientificDirectorandDirectorofImmunologyandDiabetesResearchPrograms,VirginiaMasonResearchCenter,Seattle

WilliamV.Tamborlane,M.D.ProfessorofPediatrics,YaleUniversitySchoolofMedicine,NewHaven,Connecticut

ADVISORy BOARD:Mr.MichaelBoltonSirMichaelCaineMs.NatalieColeMr.andMrs.RobertA.DalyTheHonorableDianaDeGette,U.S.HouseofRepresentatives,ColoradoMr.NeilDiamondMr.PlacidoDomingoMrs.GeraldR.FordMr.DavidFosterMr.KennyGMr.DavidGeffenMs.WhitneyHoustonMr.QuincyJonesMs.SherryLansingMr.JayLenoMr.PaulMarcianoMr.MoOstinTheHonorableandMrs.BillRitter,GovernorandFirstLadyofColoradoSirSidneyPoitierMrs.RonaldReaganMr.LionelRichieMrs.AdrienneRustonFitzgibbons

Mr.GeorgeSchlatterTheHonorableArnoldSchwarzenegger,GovernorofCalifornia,andMs.MariaShriverMr.StevenSpielbergandMs.KateCapshawMissJoanvanArkMs.BarberaThornhillMr.GaryL.WilsonMr.StevieWonder

ADVISORy BOARD, THE GUILD PRESIDEnTS:FoundingPresident,AmyDavisMrs.JamieAngelichMrs.KarenAylsworthMrs.LindaBroughtonMrs.JoyBurnsDr.BonitaCarsonMrs.NancyCoweeMrs.NormaD’AmicoMissDonnaDouglasMrs.MargyEpkeMrs.ChrisFosterMrs.HelennFranzgroteMrs.SallyFrerichsMrs.DebbieGradisharMrs.HelenHanksMrs.MartyJensenMrs.GailJohnsonMrs.SharonKamenMrs.JanetKniselyMrs.SuzyLoveMrs.SallyNewcombMrs.GretchenPopeMrs.CarolRogerMrs.KayStewartMrs.DianeSweatMrs.MelissaTuckerMrs.LorettaTuckerMrs.JaneWeingarten

FOUnDATIOn:ChristineLerner,ExecutiveDirector

Children’sDiabetesFoundation

atDenver,Colorado

777GrantStreet,Suite302

Denver,CO80203

AddressServiceRequested

NonprofitOrg.

U.S.POSTAGE

PAIDDenver,CO

PermitNo.1752

BdC ExPaNdS TyPE 2 dIaBETES CaRE & RESEaRCH IN PaRTNERSHIP wITH CHIldREN’S HOSPITal

— George Eisenbarth, MD, PhD, Executive Director of the Barbara Davis Center for Childhood Diabetes

herearemanyformsofdiabetes,andforthebest clinicalcareitisimportanttoknowwhichformof diabetesanindividualhas.InchildrenType1diabetes isthemostcommonandresultsforautoimmune destructionofthecellsthatmakeinsulin.Whiletype2diabetesisthemostcommonformofdiabetespresentinginadults,itisincreasinginchildren.AttheBarbaraDavisCenterwediagnoseandcareforallchildrenwithdiabetesandtherearemanyformsmorethantype1and2.Inparticular,wecarefortype2childrenattheBDCandDr.PhilZeitlerofChildren’sHospitalhasaspecifictype2clinicatourcenter.OneofDr.Slover’snewresponsibilitieswillbetoorganizecareofchildrenatChildren’shospitalwhohavediabetesduetocysticfibrosisandcancertherapy.Wealsoarehelpingtodefinehowmanychildrendeveloptype2formsofdiabeteswiththeNationalInstitutesofHealth“Search”studyandwithstudiesofthepathologyofpancreasofyoungadultswhohaveunfortunatelydiedwithdiabetes(JDRFnPODinternationalstudy).

Bothtype1andtype2diabetesareincreasingdramatically.Fiveto10percentofpatientswithtype2diabeteshaveautoimmunetype1diabetes,andfortunately,theanti-isletantibodytestswehavehelpeddevelopnowallowproperdiagnosis.Mostpatientswithtype2diabeteseventuallyneedinsulin.Wearestudyingnewtherapiesapplicabletoboth.

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