HUMAN PHYSIOLOGY 201Course Syllabus*

Winter Term 2012

COURSE DIRECTOR: COURSE ADMINISTRATOR:

Elizabeth M. Rust, Ph.D. Michele BoggsOffice: 7708b Med Sci II Office: 7744 Med Sci IIPhone: 615-3173 Phone: 936-2355E-Mail: emrust@umich.edu E-Mail: mboggs@umich.eduOffice Hours: TBD

TEXTBOOK:VANDER’S HUMAN PHYSIOLOGY: The Mechanisms of Body Function.E.P. Widmaier, H. Raff and K.T. Strang, McGraw–Hill Book Company, 12 th Edition, 2010 with CONNECT.

LECTURE FIGURES: Available on the web site. Contains most of the figures used in lecture. Each unit will have its own folder. You may print them at your convenience to bring to class. The files are Powerpoint files, which can be printed as handouts with 2-9 slides per page. Slides are in color.

ONLINE INTRODUCTORY COURSE MATERIAL: REQUIRED. See page 8 for details.

COURSE WEB SITE: Go to ctools.umich.edu/portal. Login. Click on the Physiol 201 tab.

LECTURES: M-W-F from 10:10 – 11:30 AM. Lecture will start promptly at 10:10 AM.I will send the room as soon as I have the information. It will be at the Medical SchoolSee map on next page for Med School Building locations:First Lecture: Wed., January 4, 2012

DISCUSSION SECTIONS: Optional, but can receive extra credit points by attending. See page 7 for more details.

OFFICE HOURS: I will post open office hours, for which you do not need an appointment. If you cannot make these scheduled office hours, or if you have a matter to discuss which requires privacy, you are welcome to make an individual appointment with me at another time.

REQUIRED ITEM: Flash Drive or Jump Drive or Thumb Drive or CD…some sort of portable mass storage device. Homeworks should be saved on this device often. Computer crashes, virus on computer, UM computer discarded your paper, etc, are all unacceptable excuses for not submitting or late submission.

*Revised 1/10/2012- Policies and information are subject to revision and/or modification at any point at the discretion of the course director.

Physiology 201– Winter 2012

207 = Med Sci II (MS II), the circular portion on the left is where NLH, WLH and SLH are located ( 3rd

floor). Also, FSSC (Furstenberg) rooms are on 2nd floor of MS II: 2710, 2733, 2737Buhl = very front of 207, closest to Catherine St., location of room 5915203 = Med Sci I, A Wing (MS I), location of 3330 and 5330 on 3rd and 5th floor respectively.208 = Taubman Medical Library, location of 2901 and 2903Parking areas are open to the public at 6 PM.Doors to Med Sci II are locked by 5:30 PM, but can gain access via Taubman Library doors, which are open. Take hallway to right, then doorway on right into Med Sci II.

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Physiology 201– Winter 2012

Lecture Schedule: Unit 1Lect Date Day Topic Chap. Pages Meeting Room1 Jan 4 W Intro. to the Course

Framework/HomeostasisIntroductory Quizzes Available

1 11th: 1-1312th: 1-15

5330, Med Sci I

2 6 F Membrane Potential Content Quiz 1 available

6 11th: 138-15712th:: 142-147

5330, Med Sci I

3 9 M Membrane Potential and Excitable Cells 6

11th: 138-15712th: 147-155

5330

4 11 W Finish Excitable Cells Neural Tissues and Synapses

6 11th: 159-18612th: 156-165

5330

5 13 F Introductory Quizzes are Due! Nervous System Structure Sensory Physiology - IntroContent Quiz 2 available

7 11th: 192-200, 206-21612th: 169-181, 187-196

5330

6 16 M MLK Day- No Class

7 18 W Vision 11th: 206-21612th: 202-212

5330

8 20 F Homework 1 dueHormones

11 11th: 317-336, 342-34512th: 312-331

5330

9 Jan 23 M Exam 1 5330 + 2nd room TBD

Important Due Dates: Unit 11. Tues. 1/10: Content Quiz 12. Fri. 1/13: Introductory Quiz 1 and Introductory Quiz 23. Tues. 1/17: Content Quiz 24. Fri. 1/20: Homework 1 due5. Mon. 1/23: Exam 1. 8 lectures. 41 questions.

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Physiology 201– Winter 2012

Lecture Schedule: Unit 2Lect Date Day Topic Chap. Pages Meeting Room1 25 W Muscle: Skeletal- Introduction,

Sarcomere, filaments9 11th: 255-263

12th: 251-2595330, Med Sci I

2 27 F Muscle: Skeletal- NMJ, single fiber mechanics, fatigueContent Quiz 3 available

9 11th: 261-27412th: 259-269

5330

3 Jan 30 M Skeletal Muscle-Whole Muscle & dysfunction

9 11th: 274-28012th: 269-274

5330

4 Feb 1 W Smooth Muscle 9 11th: 284-29012th: 279-285

5330

5 3 F Homework 2 DueCardiovascular system- Blood, F = P/R, Anatomy, Cardiac Muscle, Conducting System, ECG, Content Quiz 4 available

9&12 11th:290-291, 360-382 12th: 285-287, 354-367

5330

6 Feb. 6 M CV: Cardiac Cycle, Valves/murmurs, CO, SV, HR, VR

12 11th: 384-40312th : 367-375

5330

7 8 W CV: Blood vessels, Autonomic and hormonal inputs, Capillary exchange, lymph

12 11th: 405-42412th: 377-395

5330

8 10 F CV: Regulation of Blood Pressure Content Quiz 5 available

12 11th: 413-42412th: 397-402

5330

9 Feb. 13 M Complete previous lecture 533010 15 W Exercise/Training, Heart Disease 12 12th: 405-416 533011 17 F CV: Hemostasis (blood clotting) 12 11th: 425-437

12th: 417-4275330

12 Feb 20 M Homework 3 dueOverflow Lecture

5330

13 Feb 22 W Exam 2 5330, Med Sci I + 2nd room TBD

Important Due Dates for Unit 21. Tues. 1/31 Content Quiz 32. Fri. 2/4 Homework 2 3. Tues. 2/7: Content Quiz 44. Tues. 2/14: Content Quiz 55. Mon. 2/20: Homework 3 due6. Wed. 2/22 Exam 2: 12 lectures. 46 questions.

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Physiology 201– Winter 2012

Lecture Schedule: Unit 3Lect Date Day Topic Chapter Pages Meeting Room1 Feb 24 F Respiration-Mechanics,

Compliance13 11th: 443-457

12th: 435-4455330, Med Sci I

Feb 25-Mar 4

Winter Break No Class

5330

2 Mar. 5 M Respiration- Airway resistance 12th: 445-448 5330

3 7 W Respiration-O2/CO2 Exchange /Transport

13 11th: 457-46912th: 448-459

5330

4 9 F Respiration: Regulation of breathingContent Quiz 6 available

13 11th : 469-47812th: 460-468

5330

5 Mar. 10 M Video: Everest, The Death Zone 5330

6 12 W Renal- Basic Processes, GFR, Glucose, Na+ and H2O handling

1414

11th: 486-50312th: 476-491

5330

7 14 F Homework 4 DueRenal- Na+,H2O, & K+ RegulationContent Quiz 7 available

14 11th: 503-51512th: 491-503

5330

8 Mar. 19 M Renal- Volume and Osmolarity Problems

5330

9 21 W Renal- H+ Regulation 14 11th: 517-52212th: 506-511

5330

10 23 F Renal- Ca2+ and Kidney Failure 10th: Ch.1411th: Ch. 11 and Ch. 14

11th: 352-355, 523-52512th: 345-348, 503-504, 512-514

5330

11 Mar. 26 M Homework 5 DueOverflow lecture

5330

12 28 W Exam 3 5330, Med Sci I + 2nd room TBD

Important Due Dates for Unit 3:1. Mon. 3/10 Homework 42. Tues. 3/11: Content Quiz 63. Tues 3/20: Content Quiz 74. Mon. 3/26: Homework 55. Wed. 3/28: Exam 3. 11 lectures. 46 questions.

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Physiology 201– Winter 2012

Lecture Schedule: Unit 4, Final ExamLect Date Day Topic Chapter Pages Meeting Room1 Mar 28 W GI- Basic Processes 15 11th: 528-

54012th: 517-528

5330, Med Sci I

2 30 F GI- Regulation of GI processesContent Quiz 8 available

15 11th: 540-55712th: 528-544

5330

3 Apr 2 M Finish GI/Start Endocrine 53304 4 W Endocrine- Metabolism

Absorptive/Postabsorptive states16 11th: 567-

57812th: 555-560

5330

5 6 F Endocrine- Metabolic Regulators Diabetes Case/ProblemContent Quiz 9- available

16 11th: 578-58212th: 560-567, 581-583

5330

6 9 M Reproduction- General Principles and Male Reproduction

17 11th:599-61312th:587-600

5330

7 11 W Homework 6 DueReproduction- Female

17 11th:615-62712th:603-614

5330

8 13 F Reproduction-Pregnancy, parturition and lactation

17 11th:627-64012th: 614-627

5330

9 16 M Exam 4 5330, Med Sci I + 2nd room TBD

April 23 Mon Final Exam: Cumulative over 4:00 PM – 6:00 PM

Rooms TBD

Important Due Dates: Unit 41. Tues. 4/3: Content Quiz 82. Tues. 4/10: Content Quiz 93. Wed. 4/11: Homework 64. Mon. 4/16: Exam 4. 8 lectures. 41 Questions 5. Mon. 4/23: Cumulative Final Exam. 72 Questions.

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Physiology 201– Winter 2012

DISCUSSION SECTIONSAttendance at Discussion Section is optional, HOWEVER, attendance will be taken, and you can gain up to 0.25% extra credit for attending the section for which you are registered, based on the following attendance schedule:

Number of Absences Extra Credit Received0-3 0.25%4-6 0.15%7-9 0.1%

10-13 0

You will receive the extra credit only if you attend the section for which you are registered. You are permitted to miss 3 discussion sessions for any reason and still receive full attendance extra credit. With more than 3 absences, extra credit is reduced as shown, with no exceptions or excuses considered. Every student is allowed 3-and-only-3 absences to receive the full bonus. If more than 3 absences occur, for ANY reason, then extra credit is reduced as described above. Therefore, wisely use your allowed absences. Skipping 3 early sessions and then missing due to sickness later in the semester will not gain you any additional allowed absences. The % extra credit will be added to your final course grade. 2739/2743 are on the 2nd floor of Med Sci II Bldg in an area called the FSSC.TML stands for Taubman Medical Library. 2901 is on the 2nd floor of the library.

.See map on page 2 for locations of rooms.

Section #

Day Time First Meeting

Room # (First Meeting)

Instructor

002 Thursday 9:00 AM Jan. 12 2739 MS II Jacob Bermudez (jbermu)

003 Thursday 9:00 AM Jan. 12 2743 MS II Gail Butler (gcbutler)

004 Friday 9:00 AM Jan. 13 2813 MS II Chun-Shu Wong (chuwong)

005 Friday 9:00 AM Jan. 13 2817 MS II Bryan Holtz (bjholtz)

006 Friday 9:00 AM Jan. 13 5330 MS I Joel McDade (jmcdade)

007 Thursday 9:00 AM Jan. 12 2901 TML Joel McDade (jmcade)

***THE FIRST DISCUSSION SECTIONS WILL MEET ON:***Thursday, January 12, 2011

Friday, January 13, 2011

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Physiology 201– Winter 2012

ONLINE (REQUIRED) INTRODUCTORY TUTORIALS AND QUIZZESOn the Physiology Ctools web site, in Resources, there is a folder titled “A. Introductory Course Material”. Within this folder are four files, two of slides and two of associated notes for this background material. The slide and note files list text readings that coincide with the slides and notes. There are also two LINKS to the quizzes in UMLessons. You should study this material ON YOUR OWN and then take the quizzes that are located on UMLessons. Introductory Quiz 1 has 20 questions and is worth 20 points. Introductory Quiz 2 has 10 questions and is worth 10 points. The quizzes will be available for you to take between January 4, 2012 and January 13, 2012. You MUST submit the quizzes by 11:59 PM on Friday, January 13. You can take each quiz as many times as you want until you achieve 100% or an acceptable score for you. The quiz questions and question answers will be shuffled with each attempt, so you will not see the exact same quiz each time you attempt it. These quizzes are REQUIRED. If you do not take them you will lose 30 points. This introductory quiz material is NOT questioned directly on Exam 1.

ONLINE COURSE CONTENT QUIZZES At the end of most weeks, an online quiz will be posted. These Content Quizzes will be available via the Test Center tool on the CTools website. You will have from ~5 PM on Friday until Tuesday (due time will be posted with the Quiz- you must pay attention to it). See the Lecture Schedule on pages 3-6 for the quiz dates. Quiz material will cover untested/unquizzed lecture material presented prior to the quiz due date. You can take each quiz one (1) time in the time period that it is available. Quizzes 1-9 are worth 5 points each, and 1 score will be dropped.

EXAMINATIONSCourse examinations will be based upon the subject matter presented in lecture, and test questions will be drawn from the lecture material. The textbook is highly recommended, but lecture material and figures should receive priority when studying for the exam.

There will be 4 objective examinations in class during the semester and a Final Exam is cumulative over Units 1-4. These objective examinations will consist of multiple choice, matching and true/false questions. Statement on Cheating:Cheating will not be tolerated. If cheating is suspected for any reason, students may be asked to move to a new location, turn in their exam as is, or leave the course. After review, students may receive 0’s on the exam and cases may be referred to a student’s dean for consideration of Academic Misconduct charges.

EXAMINATION TIMESExam Lectures Questions/lecture Day/Date/Time

Examination 1 8 lectures 41 total questions~5 per lecture

Monday, January 23, 2012In class

Examination 2 12 lectures 46 total questions 4-5 per lecture

Wednesday, February 22, 2012In class

Examination 3 11 lectures 46 total questions 4-5 per lecture

Wednesday, March 28, 2012In class

Examination 4 8 lectures 41 total questions~5 per lecture

Monday, April 16, 2012In class

Final Exam Cumulative 72 total questions1-2 per lecture

Monday, April 23, 20124:00 – 6:00 PM

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Physiology 201– Winter 2012EXAMS ON FILECopies of the exams from Fall, 2011 are on the Course Web Site for you to use as a study tool.

CALCULATING EXAMINATION SCORE PERCENTAGEIt is recognized that an occasional question may be unintentionally written or interpreted in an ambiguous manner. It is for this reason that an “extra” question is asked on each exam. For Exams 2 and 3, your percentage score can be determined by dividing the number correct by 45 (1 extra question) and for Exams 1 and 4, dividing by 40 (1 extra question). For the Final Exam, your percentage score can be determined by dividing the number correct by 70 (2 extra questions).

Examination scores (number of questions answered correctly) will be posted on the Ctools web site in the Gradebook Tool. Exam scores cannot be given out over the telephone or email.

MISSED EXAMINATIONS- MAKEUP/ALTERNATE EXAMSFor all exams, approval for a Makeup/Alternate Exam will be given to those who must travel for University-associated business or those who have a medical or emergency situation (which can be documented for me) arise before the exam.  "Vacation" type trips are not valid for an excused absence at any time.

I MUST BE CONTACTED BEFORE THE MISSED EXAM AND NOTIFIED OF THE PROBLEM TO DETERMINE IF IT IS VALID AND WHAT TYPE OF DOCUMENTATION IS REQUIRED. EXCEPTION IS SUDDEN EMERGENCY SITUATION REQUIRING YOUR IMMEDIATE ATTENTION THAT DEVELOPS JUST BEFORE THE EXAM IS SCHEDULED. YOU MUST THEN CONTACT ME AS SOON AS POSSIBLE TO EXPLAIN AND DISCUSS THE OPTIONS AVAILABLE.

Except for documented University-associated business or documented emergency/medical situations, all students must take the exam when it is regularly scheduled. This includes the FINAL EXAM. Early exams are not offered before the scheduled day of the exam. The Makeup/Alternate Exam is a different exam (similar difficulty level) from the scheduled exam and occurs after the original exam time. Depending on circumstances, same day, but earlier time may be possible for an alternate exam. The makeup exam will be scheduled for the earliest possible time after the original exam.

HOMEWORK ASSIGNMENTSThere will be six (6) homework assignments. The assignments will be available on the web site. The value of all the assignments combined will be 120 points, with between 15-25 points per assignment.

Assignments must be submitted electronically via the web site. After submission you will receive an email from CTools verifying successful submission. If you, for some reason, submit by email to me, I will reply to confirm receipt of your assignment. It is the student’s responsibility to verify that his/her assignment has successfully submitted. If you do not receive a verification email, then your submission was unsuccessful and you need re-submit. Due times and late submission deadlines will be clearly outlined in the assignment instructions. It is the student’s responsibility to know the deadlines and consequences of late submission as outlined in each assignment’s instructions.

Absolutely no leniency on submission requirements will occur unless you require hospitalization or another similar major catastrophe/crisis which you can document occurs at/very near the time of submission. In such a case, the student must contact me as soon as he/she is aware of the issue with submitting the assignment. It is expected that notification will occur before the submission deadline

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Physiology 201– Winter 2012unless this is physically impossible, and as soon as reasonable possible if contact before the deadline is impossible. Late submission is not permitted for individual “computer emergencies”- you must have a backup file on a portable storage device and allow enough time to submit in case of a computer issue.

Examples of invalid late excuses (this is NOT a complete list): “I thought I clicked submit”. It is YOUR responsibility to confirm that your assignment has

been posted to the web site. Check that it posted after you click “submit” to be sure. “My computer did something weird and the assignment disappeared”. Always save a backup

copy on disk or flash drive and save often! “My internet connection failed” or “My computer crashed” or “I pushed submit at 11:57, but it

didn’t go through until 12:01”. Allow extra time for submission as it is not always instantaneous.Cheating/Plagiarism Statement:1. You are responsible for the security of your electronic files and of hard copies of your

documents. Do not send or lend your submitted homework document to anyone else. If another student (or students) submits your document, you will be held responsible and all students involved will receive a 0. Academic misconduct charges may be brought against students in such a situation.

2. You may work together on the written assignments, but answers must be submitted in your own words. Each of you has the responsibility of writing your answers in your own words. Each of you also has the responsibility of protecting your answers and not allowing others the opportunity to cheat off of you. Do not give your final answers (electronic or hard copy) to another student. If multiple students submit identical or nearly identical answers, they will ALL receive a score of 0 for that question. Academic misconduct charges may be brought against students in such a situation.

3. Plagiarism (copying) of internet, textbook or other resources without proper paraphrasing and/or citation is also not permitted. All answers must be in your own words. Academic misconduct charges may be filed if plagiarism is discovered. It is also unacceptable to quote resources, even with proper citation. You must write the answer in your own words. Although not an academic misconduct issue, a quoted answer with citation will receive a 0 for failure to follow instructions.

Grading of Assignments:The assignments will be graded by the GSI’s or Dr. Rust. Each GSI will grade one (1) assignment for ALL students. In other words, a single grader will be grading all ~180 student papers. Due to the large number of students in the class, grading may take 2-3 weeks to complete. Grades will be posted online on CTools once all assignments are graded. Assignments will be returned via the CTools website.

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Physiology 201– Winter 2012

ADDITIONAL COURSE CREDITATTENDANCE AT DISCUSSION SECTIONSAs described on page 7, you can receive up to 0.25% added to your course subtotal for attending the Discussion section for which you are registered. Attendance will be taken at Discussion. Remember, you must attend the section for which you are registered to receive credit.

RETURN OF COURSE EVALUATION FORMSNear the end of the semester, you will be notified about the online questionnaire evaluating this course and its instructors. You will receive 0.25% (1/4 of a percentage point) added to your course grade for returning the Evaluation form. The evaluation is anonymous. We receive a list of all who responded, but your name is not associated with your ratings and comments.

CALCULATING COURSE GRADEYour course grade is determined from the sum of your scores on the Introductory quizzes, Content quizzes (1 quiz dropped from the first 8 quizzes), Exams and Homework Assignments divided by the total number of points available plus any extra credit. THERE IS NO CURVE:

Exam or Assignment Points Available

Percentage of Final Grade

Quizzes (Introductory = 30, Content = 40 points)

70 16.3%

Exams 240 55.8%Written Assignments 120 27.9%TOTAL POINTS 430 100%

Example of calculating course grades:Exam or Assignment Points Received Points Possible

Introductory Quizzes 30 (100%) 30Content Quizzes 1-9 (drop 1 score) 37 (92.5%) 40Unit Exams 1-4 (170 points) 145 (85.3%) 170Cumulative Final Exam (70) 60 (86%) 70Homework Assignments 113 (94.2%) 120SUBTOTAL 385 430Discussion Missed 1 + 0.25%Evaluation Submitted + 0.25%Course Grade: 385/430 = 89.53% = B+Discussion Bonus + 0.25%Evaluation Return + 0.25%Adjusted Course Grade = 90.03% = A-

Course letter grades will be assigned on the following scale. Note that grades are NOT rounded up. Plus and Minus grades will be given:

A+ 97-100% B+ 87-89.99% C+ 77-79.99% D+ 67-69.99% E 50-59.99%A 93-96.99% B 83-86.99% C 73-76.99% D 63-66.99% F 0-49.99%A- 90-92.99% B- 80-82.99% C- 70-72.99% D- 60-62.99%

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