200

203251028

4 10

1

T3,T4

a.TSH

b.

c.

d.LDL

e.

a,eTSH

b

dLDLLDL

A10097

2

a.TSH

b.freeT3

c.freeT4

d.

e.

a,c

a.TSH

b.T3

c.T4

d.

e.

A10097

3

a.

b.

c.

d.

e.

b,c

b.

c.

A10097

4

a.

b.

c. TSH(TRAb)

d.

e. 99mTc

a,c

()

a.()(AST,ALT)

b.

c.TRAb

d.

e.

A10015

5

TSH

a

b

c

d

eT4

d

4TSH

TSH

vol.3

A10017

6

a.

b.Tc

c.

d.

e.TSHfreeT4

a,c

a.2030

b.P173

c.

d..

e.TSHfreeT4TSHT4

A10097

7

a. TRH

b.

c.

d.

e.

c,e

1

(WBC) 2000 or (Neu) 500

2

ASTALT

3

4

5 MPO-ANCA

c.

e.

A10027

8

2

a.

b.

c. 8090%

d. T4

e. (FNA)

a,e

a.16

b.

c.

d. T3,T4TSHTSH

e.

9

Afree T4,free T3,TSH

AT41

a,TSH

b,free T4

c,

d,

e,2

d

CEA

P226

P226-227

A10033

Christiano Ronaldo

10

2

a

b

c22

d

e

a,b

a

b

c

d

e

a 8~9

b

c MEN2

d

e

vol.3

11

762

: 7.8g/dl3.4g/dl 31.8mg/dl 1.41mg/dlCa 12.2mg/dlPi 4.6mg/dl 92mg/dl

:Ca 16.2mg/dl 30.3mg/dl

a)Ca11.6mg/dl

b)

c)

d)

e)

c,e

CaPiD

a) Ca=Ca+(4-)=12.2+(4-3.4)=12.8

b) CaPiDCaPiPTHrP

D

c)

d) Ca

e) Ca

09

A10041

12

29112/64mmHg

7.2g/dL3.8g/dL13.6mg/dL

0.63mg/dLCa 7.2mg/dLPi 4.9mg/dL

intact PTH 10.8pg/mL10-60

2

a. Ellsworth-HowardcAMP

b. TRP

c.

d. 1,25D

e. Trousseau

b,e

4.0g/dLCa

CaCa47.243.87.4mg/dL

Ca8.510mg/dLCa

Pi2.54.5mg/dLintact PTHCaChvostek

a. Ellsworth-HowardPTHcAMPPcAMP

b. PTHTRP

c. D1,25D

d. PTH1,25D

e. CaTrousseau

vol.3

A10

13

a

b

c

d

e

c,d

a

1,25-(OH)DCa

b

c

d

PHPPTHPTHCaP

e

3

A10052

14

1

a.

b.

c.Ca

d.1

e.Ca

c

PTH

CaP

c.Ca

vol.3p.231

15

a:30

b:50

c:MLOCC

d:3

e:

a,e

a: 4050

203050

2

5040

0.3

e: ()

16

a.

b.

c.

d.10

e.

c

a.

b. 80

c.

d.

e.

d.e.c.c.

99

17

5

a

b

c

d

e

d,e

X

L-dopaGHRP1530

http://allabout.co.jp/gm/gc/392016/2/

A10

18

72

a.

b.

c.

d.

e. GnRH

c,d

(b.)

e.GnRHGnRH()

a.

MRI

c.

d.

A10072

19

CT

155.848.5kg144/76mmHgCa

MRIT2

Na 143mEq/LK 4.3mEq/LCl 106mEq/L

BUN 12.6mg/dL0.47mg/dLACTH 14.6pg/mL7.2-63.3

9.4mg/dL5.3-11.0

18.4pg/mL100

1620pg/mL100-450

9pg/mL20

18.4mg/day3.4-26.9

320.6 mg/day48.6-168.41.12mg/day0.04-0.19

1.04mg/day0.09-0.33

a.

b.

c.

d.CTCT10HU

e.

a.

b.

c. 2

d. CT10HU25HU

e.

A10

20

()

a. RET

b.

c. RET

d. 35

e. SDHBB

a,b

A:P.65

B:3

C:P.65

D:P.74

E:P.73

A10082

21

21.8CT()MRI()

a.pituitary adenoma

b.germinoma

c.craniopharyngioma

d.Rathke cyst

e.meningioma

a

09

()

a.pituitary adenoma()

b.germinoma(())

c.craniopharyngioma()

d.Rathke cyst()

T1:high,T2:low

e.meningioma()

( )

A10

22

a. T1W1

b. Gd-DTPA

c.

d.

e. MRI

c,e

09

a.

T1W1; T1W1:

T1W1; T1W1:

b.

c.

d.

e.

( )

A10

22

23

2

a HOMA-IR

b C

c

d

e

a,d

() HOMA-IR

()

p.17

1 IRI 10U/ml

2 HOMA-IR 1.0 1.73()

3

4 SSPG(Stedy state plasma glucose)

5 IVGTT/

6 ITT(Insulin tolerance test)

(1)b,d (2)a,d (3)a,e

(1)b,d (2)a,c (3)a,c

(1)c (2)b,d (3)a,e

(1)a,b (2)c,d (3)(c 4/ e 2/) (4)b,e

A10

23

24

2

a.GAD

b.

c.insulinogenic index

d.HLA-DR4

e.

b,c

2(insulinogenic index)

GADHLA-DR41

vol.3

A10097-A10100

25

2

a

bMODY3

cIRI

dIRI

e1GAD

a,d

a P9

b MODY3HNF-1MODY2MODYMaturity onset diabetes of the youngP9

c P10IRIimmunoreactive insulin

dP10

e1GADP6

26

2

a. 10g/

b. 128mg/dl

c. 75gOGTT1213mg/dl

d. 186mg/dl

e. HbA1c6.6%(NGSP)

b,e

20102012

126mg/dl

75gOGTT2200mg/dl

200mg/dl

HbA1c6.5%NSGP%

A10

27

2

A)

B)

C)

D)

E)

a,c

ACDE

BB

ABC

Sheehan

08

28

2

a SU

b

c DPP4

d

e

b,c

a SU()

b PPARPPARNa()

c DPP4(GIPGLP-1)DPP4

d (2)

e

()

vol.3

A10114

29

2

a.

b.

c.

d.

e.

a,d

a.

b. DKAWBC

c. H2ONaNaDKANa

d. DKA

e.

30

2

a.

b. ANPBNP

c. SIADHANP

d. NT-proBNP

e.

b,c

a.

b. ANPBNP

c. ADHANP

d.

e.

31

357174cm56kg886mg/dLHbA1c 6.2NGSP

a. GAD

b. pH7.45

c.

d. HLA-DR2

e. Na 128mEq/L

c,e

1

1

1

2

3HbA1c

4C-10g/day

5

6

Kussmaul

+3+Na140Eq/LpH7.3

a. b. e.

c. 211HbA1c

d. 1HLA-DR4DR9HLA-DR2

PBL1

32

562SU170cm78kg128/78mmHg156mg/dlHbA1c 8.0(NGSP)%BUN 20.6 mg/dl0.85mg/dl2

a.

b. 1800kcal

c.

d. 2

e.

a,b

aSU

b1.7222281780.24

c

d1

e

A10007

Ishikawa

33

a. LHE2

b. PRLREM

c. ACTH

d. GH

e. TSH

b,c

09d(09)

a. E2(LHsurge)

b. PRL...09

c.

d. GH()

e. TSH()

A10015

34

a.

b.

c.

d.

e.

d,e

a. 7

b.

c. paracrine

autocrine

d. m

e. TGF-MAP

vol.3 09

A10020

35

2

a.

b.

c.

d. cAMP

e. H2

b,d

a.

GHRHPRLP.171

b.

IGF-GHGHGH(P.172)

c.

d.

LHP.1664

e.

H2H2H2P.185

vol.33

9

36

a.

b.

c.

d.

e.

b,c

a

TRH

2

PIFPIFPIF

1

2

e11

A10027

37

2

a. QOL

b.

c.

d. 75gGH

e.

b,c

a.

b. GH

c.

d. 75gOGTTGH()GH1ng/ml10ng/ml

L-DOPAGHTRHGnRH

e. GH

09

38

5465

16668154/96mmHg76/

Ca 9.6mg/dL Pi 5.4mg/dL128mg/dLHbA1c 6.9NGSP242mg/dL (50-149) 218mg/dL (150-219)HDL-C52mg/dL (40-86)GH 56.4g/L (