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2 solutionsfor noninvasive blood pressuremeasurement

emkaPACK & nibpSNAPSHOT

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noninvasive blood pressuremeasurement

A

B

C

D

overview

emkaPACK

nibpSNAPSHOT

software analysis

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overview

A

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what is NIBP?a noninvasive method for measuring the blood pressure of laboratory animals (dog, primates, etc.)

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how does it work?

emka TECHNOLOGIES’ noninvasive blood pressure systems are based on the oscillometric technique: pressure is measured from a cuff around a limb or the tail that is inflated to block blood flow then deflated slowly

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what is analyzed?

time

cuff pressure

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2 different solutionsemkaPACKnibp is an optional feature of our emkaPACK noninvasive telemetry system - suitable for long term measurements on unrestrained animals

nibpSNAPSHOTself-contained, handheld device designed for single-point measurements

both supplied with dedicated software for data acquisition & analysis

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common features

low and high pressure range 0-300mmHgadjustable deflation speed5mmHg/s – 15mmHg/slinear deflation speedhigh speed servo-control by instant pressure and dPdtadjustable pulse amplification 5x-100x

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emkaPACK

B

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designed for the emkaPACK systemsingle-shot or programmable cyclic operationembedded calibration information

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setting-up the animal

tail is shaved

cuff is wrapped around the tail and connected to the transmitter

a custom velcro extension protects the cuff, and maintains it in the proper position on the tail

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nibpSNAPSHOT

C

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nibpSNAPSHOT

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features

handheld deviceUSB connection to computerpowered through USBboth a NIBP device and a 7-leads ecg devicedesigned for single-point measurementsmeasurements can be repeated every 10s if necessary

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specifications

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software analysis

D

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real-time & off-line software analysis

real-time analysis performed by iox2 (nibpSNAPSHOT, emkaPACK, emkaPACK 4G)

off-line analysis performed by ecgAUTO (nibpSNAPSHOT, emkaPACK, TOE)

control by iox2

ecgAUTO

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parameters computed from the deflation curve alone

systolic blood pressurediastolic blood pressuremean blood pressure

ecgAUTO

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parameters computed with simultaneous ecg

heart ratepressure transit time

ecgAUTO

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pulse amplitude vs cuff pressure

pressure pulses and ecg

cuff pressure vs time

real-time analysis in iox2

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pulse amplitude vs cuff pressure

pressure pulses and ecg

cuff pressure vs time

off-line analysis in ecgAUTO

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how is analysis performed?

detects inflation cyclesapplies hi-pass filterselects valid blood pressure pulsesproduces bell shaped amplitude curvecomputes mean, systolic and diastolic pressure values

ecgAUTO

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what are the challenges for a successful analysis?

when signal is noisy the algorithm picks pulses that correspond to blood pressure beats and ignores artefacts

for greater efficiency, the software applies a number of criteria and rejects unreliable or spurious results

present experience (around 1000 hours of data from 40 dogs) indicate that from 70 to 95% of inflation cycles produce reliable data

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examples of good and poor quality signals

pulses from noisy zones are ignored

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