16 cox cloudcomputing

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Nancy J. Cox, Ph.D.

The University of Chicago

http://genemed.uchospitals.edu

Cloud Computing forLarge-Scale Sequencing


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G C A C G G T T

T C C C A G T

G G T T

G T T

A G C

C G T A T T

G C A C G G T T

T T A A A C T T

C C C T

G T T

C C C

G G G C G T T

C

C


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Challenges

IRB

HIPAA

Insurance,

laws

$1000Genome

$100,000

GenomeAnalysis


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The sky wont fall;

we used to worryabout how wewould deal withthe deluge of datafrom GWAS


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What is Cloud Computing?

Anything and everything that is outthere not on your desktop or laptop

Outsourcing

IT support

Hardware

Software

A new way of doing business Scale to what you need when you need it

Dont own what you cannot use completelyefficiently


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Keys to Cloud Computing

A revolution in the virtualization ofcomputing architecture Security and connectivity can be defined

at the level of the processor Expanded and contracted as needed

Redundant and abundant (cheap) datastorage

Computational resources to processdata are local to the data


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Public Vs. Private Clouds

Private clouds can be developed tomeet any level of required security HIPAA compliant clouds with EMR data

dbGaP-level security for omics researchdata

Amazon, Google, DropBox, etc

Extremely cost effective and very reliablefor large-scale but short-term usage

Amazon hosting 1000 Genomes (and otherlarge-scale omics) data for computations


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Get Your Amazon GrantApplication in Soon!


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Public Clouds Scientific Commons


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HIPAACLO

UD



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HIPAACLO

UD


CDW

DM

AUX


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HIPAACLO

UD


CDW

DM

-omics

results

AUX

Sequencing Core

-omicsdata


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HIPAACLO

UD


CDW

DM

-omics

results

AUX

Sequencing Core

-omicsdata

CLIA Lab


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HIPAACLO

UD


CDW

DM

-omics

results

AUX

Sequencing Core

-omicsdata

My localdropbox

CLIA Lab


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HIPAACLO

UD


CDW

DM

-omics

results

AUX

Sequencing Core

-omicsdata

My localdropbox

CLIA Lab


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HIPAACLO

UD


CDW

DM

-omics

results

AUX

Sequencing Core

-omicsdata

My localdropbox

CLIA Lab


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HIPAA

CLO

UD


CDW

DM

-omics

results

AUX

Sequencing Core

-omicsdata

cluster

My localdropbox

CLIA Lab


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HIPAA

CLO

UD


CDW

DM

-omics

results

AUX

Sequencing Core

-omicsdata

cluster

My localdropbox

CLIA Lab

ENCODE

1KG


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Colleagues & Collaborators

Bob Grossman Ian Foster Kevin White


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HIPAA

CLO

UD


CDW

DM

-omics

results

AUX

Sequencing Core

-omicsdata

My localdropbox

CLIA Lab

16 cox cloudcomputing

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