*

*

151*

292

*

*

*

*

*

31 43 151 284 137 153 5073638 500 120 673

151 1663 134 660

3638 500 238 673

151 166 1533638 500 1046

151 284 5073638 500 930

151 292 6603638 500

249673

151 6603638 500 810

31 43

31 43

31 43

43

43

5

*

*

*

292 112

*

*

151500

1345283

58 31

Isoform 4 (NM_0017509)(classical form)

Isoform 1 (NM_023006)(exon 3 truncation)

Isoform 3 (NM_138464)(exon 3 truncation, missing exon 4)

Isoform 2 (NM_138563)(missing exon 4)

Isoform 5 (AY373373)(intron 3 retention)

Isoform 6 (AY373374)(intron 3 retention, missing exon 4)

BP428687.1, BP431267 and

BP431386 (exon B variant, missing exon 1,

3’ end unknown)

H D S

* *9931 43 151 284 137 153 507

5591 3638 500 120 673 *

CF139951 (exon A variant, 3’ sequence from Kurlender et al

*

Exon A B 1 2 3 4 5

A

B

β2M

1 2 3 4 5 614470KLK15 Exon B variant

249