12-new physiology of the eye
TRANSCRIPT
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PHYSIOLOGY OF THE EYE
Dr.Budu, Ph.D, Sp.M (K)
Department of Ophtlmology, Faculty of Medicine,
Haanuddin !ni"erity, Ma#aar
$%&&
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'natomy
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Eye ball organs
1. Eyelid
2. Tears
3. Kornea
4. Huor a!uous
". #$ea %iris& 'iliary body& '(oroid)
*. Lens
+. ,i-reous. /e-ina and $isual 'or-e0
. o-or (ysiology o -(e eye
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Palpera *ye lid
Fun'-ion 5 -o re$en- -raua
-o re$en- e0'essi$e lig(-
-o dis-ribu-e eye -ears
-o oen6'lose -(e eye
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T(ere are 2 ior-an- us'les in eye lids 5
1. M. Levator palpebra
6 Ele$a-ion7'on-ra'-ion o eyelid 8.. Oen -(e eye %9.III)
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2. M. Orbicularis oculi
- Blink .. Pars palpebralis
- Close the eye ..pars orbitalis
- Tightly close the eye .. Pars tarsalis
T(e 3 un'-ions: 'on-ra'-ion o -(e . orbi'ularis o'uli %9.,II)
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+ear
Function of the tears :
1. /eleasing edia o 'ell des!uaa-ion
2. O0ygen sulay -o 'ornea
3. ;n-ii'roba
4. Palebra6'ornea lubri'a-ion a-erial
". To re$en- dryness o e0-ernal sura'e o -(e eye.
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Tears are produced by 2 systems :
&. acrimal gland -mayor refle/ ecretion.
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$. acrimal gland-acceoriu Kraue and 0olfring 1. aic ecretion.
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Sebagian besar air a-a engalir elalui oa a
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+ear layer
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Tear il 'oonen-
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Tears consists of 3 layers :
1. Liid layer %sueri'ial layer)& rodu'ed by eibo gland
To re$en- e0'ess o -ears dryness.
To i0 -(e (ydro(obi' barrier To i0 -ears enis'us.
2. ;!uous layer %ediu layer)& rodu'ed by Krause and
>olring glands.
O0ygen sulier
;n-ii'roba
?orneal sura'e edia
/elease 'orneal sura'e un@an-ed a-erials
To adAus- -(e un'-ion o 'orneal sura'e 'ell.
3. u'in layer & rodu'ed by goble- 'ell
To al-er (ydro(obi' -o (ydro(yli' un'-ion
For eyelid lubri'a-ion
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+ear function tet (Schirmer +et)
E$alua-ion5
6 9oral
>e--ing o >(a-an aer 51B63B
6 Corderline dry eye
>e--ing >(a-an aer 5 "62B
6 =ry eye
>e--ing >(a-an aer 5 D "
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2ornea
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?orneal layers
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?orneaT(e ain 'orneal un'-ions 5
6 /era'-ion edia
6 Carrier o eye ball 'on-en-s
?orneal e-aboliss ro'ess 5
1. Glu'ose and gly'ogen e-aboliss
2. O0ygen e-aboliss
3. ;ino a'id e-aboliss.
?orneal endo-(elial un'-ion 5
1. Carrier o a!uous (uor -o diuss in-o s-roa.
2. ;'-i$e e-aboli' u o @a-er ro s-roa.
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e-aboli' u in 'ornea
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#$eal -ra'- dan ;!uous (uor
I. Iris and pupilM. Spinter pupil& 'on-ra'-ion 8. yosis o uil
M. delatator pupil& 'on-ra'-ion 8. ydriasis7dela-a-ion o
uil
Puil un'-ion5 -o arrange lig(- in-o -(e eye .
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yosis ydriasis
2
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Puillary lig(- rele0 in general5
Lig(- en-ers -(e eye
-(e uil 'ons-ri'-s
2
3
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Directuillary rele05
Lig(- goes in oneeye
-(e ipilateraluil 'ons-ri'-s
3
iosis
4
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2onenual (indirect)uillary rele05
Lig(- goes in oneeye
the contralateraluil 'ons-ri'-s
4
iosis
"
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9er$es in$ol$ed5
O-i' ner$e %9.II) is -(e sensory ner$e
specifically, the pre-ganglionic fibers
from the Edinger-Westphal nucleus
travel in the oculomotor nerve to
innervate the ciliary ganglion neuronsthat activate the constrictor muscle
of the pupil
Oculomotor nerve (N III) is the motor nerve
"
*
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T(e @iring
ciliaryganglion
RETINA
ciliaryganglion
CHIASM
PRETECTAL
NUCLEUS
PRETECTAL
NUCLEUS
EDINGER
WESTPHAL
NUCLEUS
CN 3 CN 2
EDINGER
WESTPHAL
NUCLEUS
*
+
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9eural a-(@ays or directrele0
lig(- goes in one eye
then to ipsilateral Edinger-Westphal nucleus and
to ipsilateral pretectal nucleus
to optic tract ipsilaterally then through optic nerve
through ipsilateral oculomotor
nerve (CN)
to ciliary ganglion, then
short post-ganglionic ciliary
nerves activate the constrictor
ciliaryganglion
RETINA
ciliaryganglion
CHIASM
PRETECTAL
NUCLEUS
PRETECTAL
NUCLEUS
EDINGER
WESTPHAL
NUCLEUS
CN 3 CN 2
EDINGER
WESTPHAL
NUCLEUS
+
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9eural a-(@ays or conenualrele0
9o-e5 -(ere are 2 la'es
@(ere inora-ion 'an
'ross
!rom the pretectal
nucleus to the Edinger-
Westphal nucleus
"t the optic chiasm
ciliary
ganglion
RETINA
ciliaryganglion
CHIASM
PRETECTAL
NUCLEUS
PRETECTAL
NUCLEUS
EDINGER
WESTPHAL
NUCLEUS
CN 3 CN 2
EDINGER
WESTPHAL
NUCLEUS
#he follo$ing slides sho$ the %
routes separately, but light travels
both routes simultaneously&
1 9 l -( l l
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1. 9eural a-(@ay or conenualrele0&
'rossing a- '(ias
lig(- goes -(roug( o-i'ner$e
'rosses a- chiam-ocontralateralo-i' -ra'-
continues to pretectal nucleusand Edinger-Westphalnucleus contralateral to lightstimulus
then out through the
oculomotor nervecontralateral to lightstimulus
to ciliary ganglion, from$hich ciliary nerves
activate the constrictor
ciliaryganglion
RETINA
ciliaryganglion
CHIASM
PRETECTAL
NUCLEUS
PRETECTAL
NUCLEUS
EDINGER
WESTPHAL
NUCLEUS
CN 3 CN 2
EDINGER
WESTPHAL
NUCLEUS
2 9 l -( l l 1B
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2.9eural a-(@ay or conenualrele0&
'rossing rore-e'-alnu'leus lig(- goes -(roug( one o-i'
ner$e
-o o-i' -ra'- isila-erally
-o isila-eral re-e'-al
nu'leus
pretectal cells send a'onsacross midline in posteriorcommissure
to Edinger-Westphal
nucleus then out throughthe oculomotor nerve, bothcontralateral to lightstimulus
to ciliary ganglion, andpupillary constrictor
ciliaryganglion
RETINA
ciliary
ganglion
CHIASM
PRETECTAL
NUCLEUS
PRETECTAL
NUCLEUS
EDINGER
WESTPHAL
NUCLEUS
CN 3 CN 2
EDINGER
WESTPHAL
NUCLEUS
1B
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II. Ciliary body
Fun'-ions 5
In$ol$ing in a''ooda-ion sys-e.
Produ'-ion o a!uous (uor.
In$ol$ing in a!uous drainage sys-e
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Ciliary body
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'ccommodation
T(e abili-y o lens -o 'on$e0.;''ooda-ion ro'ess %He(ol- -(eory 5
=uring 'iliary us'le 'ons-ra'-ion 666 innii onnula rela0a-ion666
lens be'ae 'on$e0. =e'rease o lens diae-er.
'3uou Humor
Produced y non4pigmented epithelial of ciliary ody
Troug( soe (ysiologi'al e'(aniss 5 diusion& ul-rail-a-ion&
;'-i$e 'arboni' an(ydrase& a'-i$e se're-ion.Secreted to poterior chamer trough pupil to anterior chamer.
E0're-ion o a!uous (uor $ia 2 rou-es 5
-rabe'ular es(@or
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Huor a!uous un'-ion 5
1. /era'-ion edia
2. In-egri-y o eye ball s-ru'-ure.
3. 9u-ri-ion o an-erior segen-.
4. In-rao'ular regulari-y.
III. Koroid
; -issue lo'alie in -(e e0-ernal ar- o re-ina.
Cru'( ebrane o '(oroid (a$e un'-ion in a'-i$e -ransor-O -issue luid ro '(oroidal 'aillary -o re-ina.
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Lens
Lens is a bi'n$e0 s-ru'-ure& a$as'ular& and -ranarans.?onsis-s o ** @a-er dan and -(e o-(ers are ro-ein.
Fun'-ion 5
1. /era'-ion edia2. In$ol$ing in a''ooda-ion ro'ess.
3. To absorb ul-ra$iole- .
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en and dan 'ccommodation
Lens roile ;''ooda-ion >i-(ou- ;''ooda-ion
;
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5*+67'
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,isual ro'esses
T(e (ysi's o lig(- and eye5
Transission
T(e re-ina5 Transdu'-ion and
organia-ion Sensory re'e-ors5 9o a0ons
Graded receptor potentials
T(e $isual a-(@ays5 ProAe'-ion
,isual 'or-e05 Per'e-ion
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/e-inal layer
8iual path9ay
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,isual Pa-(@ay is -(e ner$e iber sis-es 'onne'-ing -(e
retinaand visual cortexin -(e o''ii-al lobe o -(e brain.
8iual path9ay conit of
6 /e-ina
6 O-i' ner$e
6 O-i' '(iasa 6 O-i' -ra'-
6 La-eral geni'ula-u body
6 O-i' radia-ion
6 ,isual 'or-e0 area
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,isual Pa-(@ay is -(e ner$e iber sis-es 'onne'-ing -(e
retinaand visual cortexin -(e o''ii-al lobe o -(e brain.
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MO+O5 PH:S6OO;: OF +H* *:*
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Basic Principles and Terms
Terinology o eye o$een-s e0lained by -@o
'on'e-s 5 T(e a0es o Fi'< and Lis-ings lane.
&. +he a/e of Fic# deigned a
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$. iting= e3uatorial plane
Lis-ing e!ua-orial lane asses -(roug( -(e 'en-er o ro-a-ion
and in'ludes -(e 0 dan . T(e y a0is is erendi'ular -o lis-inglane
Poition of ;a>e
Casi' -erinology o -(e osi-ion o gae 56 Priary osi-ion is s-raig(- a(ead.
6 Se'ondary osi-ions are s-raig(- u& s-raig(- do@n& rig(-
gae& abd le- gae.
6 Ter-iary osi-ions are our obli!ue osi-ions o gae 5 u andrig(-& u and le-& do@n and rig(-& and do@n and le-.
6 ?ardinal osi-ions are u and rig(-& u and le-& rig(-& le-&
do@n and rig(-& and do@n and le-.
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Se'ondary
Primary, Secondary, and +ertiary 'ction
edial re'-us
La-eral re'-us
Inerior re'-us
Suerior re'-us
Inerior obli!ue
Suerior obli!ue
;ddu'-ion
;bdu'-ion
=eression
Ele$a-ion
E0-orsion
In-orsion
us'le PriaryTer-iary
6
6
E0-orsion
In-orsion
Ele$a-ion
=eression
6
6
;ddu'-ion
;ddu'-ion
;bdu'-ion
;bdu'-ion
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*ye Mo"ement
I. onocular eye !o"e!ents #ductions$
1. 'dductionis o$een- o -(e eye nasally.
2. 'ductionis o$een- o -(e eye -eorally
3. *le"ation (upraduction)is an u@ard ro-a-ion o -(e eye.
4. Depreion (infraduction)is a do@n@ard ro-a-ion o -(e eye.
". 6ntorion (incicloduction)is a nasal ro-a-ion o -(e suerior
or-ion o -(e $er-i'al 'orneal eridian.
*. */torion (e/cycloduction)is a -eoral ro-a-ion o -(e
suerior or-ion o -(e $er-i'al 'ornea eridian
S(erring-ons la@
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+he important term in monocular eye mo"ement
'goni& -(e riary us'le o$ing -(e eye in a gi$en dire'-ion.
Synergi& -(e us'le in -(e sae eye a'-s @i-( -(e agonis- -orodu'e a gi$en o$een-.
'ntagoni& -(e us'le in -(e sae eye a'-s in -(e dire'-ionoosi-e -o -(a- o -(e agonis-
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II. Binocular eye !o"e!ents : ?onsis-s o -@o -yes 5
1. ,ersion %'onAuga-e bino'ular eye o$een-s) J
-(e eyes o$e in -(e sae dire'-ion.
/ig(- gae %de0-ro$ersion)
Le- gae %le$o$ersion)
#gae %sursu$ersion)
=o@ngae %doursu$ersion)
=e0-ro'y'lo$ersionLe$o'y'lo$ersion
o!e muscleis used -o des'ribe -@o us'le %one in ea'( eye)
-(a- are rie o$ers o -(eir rese'-i$e eyes in -(e gi$en
osi-ion o gae
Hering= la9
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2. ,ergen'es %dis'onAuga-e bino'ular eye o$een-)
?on$ergen'e
=i$ergen'e
In'y'lo$ergen'e
E0'y'lo$ergen'e
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Terima Kasih