12-new physiology of the eye

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    PHYSIOLOGY OF THE EYE

    Dr.Budu, Ph.D, Sp.M (K)

    Department of Ophtlmology, Faculty of Medicine,

    Haanuddin !ni"erity, Ma#aar

    $%&&

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    'natomy

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    Eye ball organs

    1. Eyelid

    2. Tears

    3. Kornea

    4. Huor a!uous

    ". #$ea %iris& 'iliary body& '(oroid)

    *. Lens

    +. ,i-reous. /e-ina and $isual 'or-e0

    . o-or (ysiology o -(e eye

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    Palpera *ye lid

    Fun'-ion 5 -o re$en- -raua

    -o re$en- e0'essi$e lig(-

    -o dis-ribu-e eye -ears

    -o oen6'lose -(e eye

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    T(ere are 2 ior-an- us'les in eye lids 5

    1. M. Levator palpebra

    6 Ele$a-ion7'on-ra'-ion o eyelid 8.. Oen -(e eye %9.III)

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    2. M. Orbicularis oculi

    - Blink .. Pars palpebralis

    - Close the eye ..pars orbitalis

    - Tightly close the eye .. Pars tarsalis

    T(e 3 un'-ions: 'on-ra'-ion o -(e . orbi'ularis o'uli %9.,II)

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    +ear

    Function of the tears :

    1. /eleasing edia o 'ell des!uaa-ion

    2. O0ygen sulay -o 'ornea

    3. ;n-ii'roba

    4. Palebra6'ornea lubri'a-ion a-erial

    ". To re$en- dryness o e0-ernal sura'e o -(e eye.

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    Tears are produced by 2 systems :

    &. acrimal gland -mayor refle/ ecretion.

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    $. acrimal gland-acceoriu Kraue and 0olfring 1. aic ecretion.

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    Sebagian besar air a-a engalir elalui oa a

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    +ear layer

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    Tear il 'oonen-

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    Tears consists of 3 layers :

    1. Liid layer %sueri'ial layer)& rodu'ed by eibo gland

    To re$en- e0'ess o -ears dryness.

    To i0 -(e (ydro(obi' barrier To i0 -ears enis'us.

    2. ;!uous layer %ediu layer)& rodu'ed by Krause and

    >olring glands.

    O0ygen sulier

    ;n-ii'roba

    ?orneal sura'e edia

    /elease 'orneal sura'e un@an-ed a-erials

    To adAus- -(e un'-ion o 'orneal sura'e 'ell.

    3. u'in layer & rodu'ed by goble- 'ell

    To al-er (ydro(obi' -o (ydro(yli' un'-ion

    For eyelid lubri'a-ion

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    +ear function tet (Schirmer +et)

    E$alua-ion5

    6 9oral

    >e--ing o >(a-an aer 51B63B

    6 Corderline dry eye

    >e--ing >(a-an aer 5 "62B

    6 =ry eye

    >e--ing >(a-an aer 5 D "

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    2ornea

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    ?orneal layers

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    ?orneaT(e ain 'orneal un'-ions 5

    6 /era'-ion edia

    6 Carrier o eye ball 'on-en-s

    ?orneal e-aboliss ro'ess 5

    1. Glu'ose and gly'ogen e-aboliss

    2. O0ygen e-aboliss

    3. ;ino a'id e-aboliss.

    ?orneal endo-(elial un'-ion 5

    1. Carrier o a!uous (uor -o diuss in-o s-roa.

    2. ;'-i$e e-aboli' u o @a-er ro s-roa.

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    e-aboli' u in 'ornea

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    #$eal -ra'- dan ;!uous (uor

    I. Iris and pupilM. Spinter pupil& 'on-ra'-ion 8. yosis o uil

    M. delatator pupil& 'on-ra'-ion 8. ydriasis7dela-a-ion o

    uil

    Puil un'-ion5 -o arrange lig(- in-o -(e eye .

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    yosis ydriasis

    2

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    Puillary lig(- rele0 in general5

    Lig(- en-ers -(e eye

    -(e uil 'ons-ri'-s

    2

    3

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    Directuillary rele05

    Lig(- goes in oneeye

    -(e ipilateraluil 'ons-ri'-s

    3

    iosis

    4

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    2onenual (indirect)uillary rele05

    Lig(- goes in oneeye

    the contralateraluil 'ons-ri'-s

    4

    iosis

    "

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    9er$es in$ol$ed5

    O-i' ner$e %9.II) is -(e sensory ner$e

    specifically, the pre-ganglionic fibers

    from the Edinger-Westphal nucleus

    travel in the oculomotor nerve to

    innervate the ciliary ganglion neuronsthat activate the constrictor muscle

    of the pupil

    Oculomotor nerve (N III) is the motor nerve

    "

    *

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    T(e @iring

    ciliaryganglion

    RETINA

    ciliaryganglion

    CHIASM

    PRETECTAL

    NUCLEUS

    PRETECTAL

    NUCLEUS

    EDINGER

    WESTPHAL

    NUCLEUS

    CN 3 CN 2

    EDINGER

    WESTPHAL

    NUCLEUS

    *

    +

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    9eural a-(@ays or directrele0

    lig(- goes in one eye

    then to ipsilateral Edinger-Westphal nucleus and

    to ipsilateral pretectal nucleus

    to optic tract ipsilaterally then through optic nerve

    through ipsilateral oculomotor

    nerve (CN)

    to ciliary ganglion, then

    short post-ganglionic ciliary

    nerves activate the constrictor

    ciliaryganglion

    RETINA

    ciliaryganglion

    CHIASM

    PRETECTAL

    NUCLEUS

    PRETECTAL

    NUCLEUS

    EDINGER

    WESTPHAL

    NUCLEUS

    CN 3 CN 2

    EDINGER

    WESTPHAL

    NUCLEUS

    +

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    9eural a-(@ays or conenualrele0

    9o-e5 -(ere are 2 la'es

    @(ere inora-ion 'an

    'ross

    !rom the pretectal

    nucleus to the Edinger-

    Westphal nucleus

    "t the optic chiasm

    ciliary

    ganglion

    RETINA

    ciliaryganglion

    CHIASM

    PRETECTAL

    NUCLEUS

    PRETECTAL

    NUCLEUS

    EDINGER

    WESTPHAL

    NUCLEUS

    CN 3 CN 2

    EDINGER

    WESTPHAL

    NUCLEUS

    #he follo$ing slides sho$ the %

    routes separately, but light travels

    both routes simultaneously&

    1 9 l -( l l

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    1. 9eural a-(@ay or conenualrele0&

    'rossing a- '(ias

    lig(- goes -(roug( o-i'ner$e

    'rosses a- chiam-ocontralateralo-i' -ra'-

    continues to pretectal nucleusand Edinger-Westphalnucleus contralateral to lightstimulus

    then out through the

    oculomotor nervecontralateral to lightstimulus

    to ciliary ganglion, from$hich ciliary nerves

    activate the constrictor

    ciliaryganglion

    RETINA

    ciliaryganglion

    CHIASM

    PRETECTAL

    NUCLEUS

    PRETECTAL

    NUCLEUS

    EDINGER

    WESTPHAL

    NUCLEUS

    CN 3 CN 2

    EDINGER

    WESTPHAL

    NUCLEUS

    2 9 l -( l l 1B

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    2.9eural a-(@ay or conenualrele0&

    'rossing rore-e'-alnu'leus lig(- goes -(roug( one o-i'

    ner$e

    -o o-i' -ra'- isila-erally

    -o isila-eral re-e'-al

    nu'leus

    pretectal cells send a'onsacross midline in posteriorcommissure

    to Edinger-Westphal

    nucleus then out throughthe oculomotor nerve, bothcontralateral to lightstimulus

    to ciliary ganglion, andpupillary constrictor

    ciliaryganglion

    RETINA

    ciliary

    ganglion

    CHIASM

    PRETECTAL

    NUCLEUS

    PRETECTAL

    NUCLEUS

    EDINGER

    WESTPHAL

    NUCLEUS

    CN 3 CN 2

    EDINGER

    WESTPHAL

    NUCLEUS

    1B

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    II. Ciliary body

    Fun'-ions 5

    In$ol$ing in a''ooda-ion sys-e.

    Produ'-ion o a!uous (uor.

    In$ol$ing in a!uous drainage sys-e

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    Ciliary body

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    'ccommodation

    T(e abili-y o lens -o 'on$e0.;''ooda-ion ro'ess %He(ol- -(eory 5

    =uring 'iliary us'le 'ons-ra'-ion 666 innii onnula rela0a-ion666

    lens be'ae 'on$e0. =e'rease o lens diae-er.

    '3uou Humor

    Produced y non4pigmented epithelial of ciliary ody

    Troug( soe (ysiologi'al e'(aniss 5 diusion& ul-rail-a-ion&

    ;'-i$e 'arboni' an(ydrase& a'-i$e se're-ion.Secreted to poterior chamer trough pupil to anterior chamer.

    E0're-ion o a!uous (uor $ia 2 rou-es 5

    -rabe'ular es(@or

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    Huor a!uous un'-ion 5

    1. /era'-ion edia

    2. In-egri-y o eye ball s-ru'-ure.

    3. 9u-ri-ion o an-erior segen-.

    4. In-rao'ular regulari-y.

    III. Koroid

    ; -issue lo'alie in -(e e0-ernal ar- o re-ina.

    Cru'( ebrane o '(oroid (a$e un'-ion in a'-i$e -ransor-O -issue luid ro '(oroidal 'aillary -o re-ina.

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    Lens

    Lens is a bi'n$e0 s-ru'-ure& a$as'ular& and -ranarans.?onsis-s o ** @a-er dan and -(e o-(ers are ro-ein.

    Fun'-ion 5

    1. /era'-ion edia2. In$ol$ing in a''ooda-ion ro'ess.

    3. To absorb ul-ra$iole- .

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    en and dan 'ccommodation

    Lens roile ;''ooda-ion >i-(ou- ;''ooda-ion

    ;

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    5*+67'

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    ,isual ro'esses

    T(e (ysi's o lig(- and eye5

    Transission

    T(e re-ina5 Transdu'-ion and

    organia-ion Sensory re'e-ors5 9o a0ons

    Graded receptor potentials

    T(e $isual a-(@ays5 ProAe'-ion

    ,isual 'or-e05 Per'e-ion

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    /e-inal layer

    8iual path9ay

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    ,isual Pa-(@ay is -(e ner$e iber sis-es 'onne'-ing -(e

    retinaand visual cortexin -(e o''ii-al lobe o -(e brain.

    8iual path9ay conit of

    6 /e-ina

    6 O-i' ner$e

    6 O-i' '(iasa 6 O-i' -ra'-

    6 La-eral geni'ula-u body

    6 O-i' radia-ion

    6 ,isual 'or-e0 area

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    ,isual Pa-(@ay is -(e ner$e iber sis-es 'onne'-ing -(e

    retinaand visual cortexin -(e o''ii-al lobe o -(e brain.

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    MO+O5 PH:S6OO;: OF +H* *:*

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    Basic Principles and Terms

    Terinology o eye o$een-s e0lained by -@o

    'on'e-s 5 T(e a0es o Fi'< and Lis-ings lane.

    &. +he a/e of Fic# deigned a

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    $. iting= e3uatorial plane

    Lis-ing e!ua-orial lane asses -(roug( -(e 'en-er o ro-a-ion

    and in'ludes -(e 0 dan . T(e y a0is is erendi'ular -o lis-inglane

    Poition of ;a>e

    Casi' -erinology o -(e osi-ion o gae 56 Priary osi-ion is s-raig(- a(ead.

    6 Se'ondary osi-ions are s-raig(- u& s-raig(- do@n& rig(-

    gae& abd le- gae.

    6 Ter-iary osi-ions are our obli!ue osi-ions o gae 5 u andrig(-& u and le-& do@n and rig(-& and do@n and le-.

    6 ?ardinal osi-ions are u and rig(-& u and le-& rig(-& le-&

    do@n and rig(-& and do@n and le-.

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    Se'ondary

    Primary, Secondary, and +ertiary 'ction

    edial re'-us

    La-eral re'-us

    Inerior re'-us

    Suerior re'-us

    Inerior obli!ue

    Suerior obli!ue

    ;ddu'-ion

    ;bdu'-ion

    =eression

    Ele$a-ion

    E0-orsion

    In-orsion

    us'le PriaryTer-iary

    6

    6

    E0-orsion

    In-orsion

    Ele$a-ion

    =eression

    6

    6

    ;ddu'-ion

    ;ddu'-ion

    ;bdu'-ion

    ;bdu'-ion

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    *ye Mo"ement

    I. onocular eye !o"e!ents #ductions$

    1. 'dductionis o$een- o -(e eye nasally.

    2. 'ductionis o$een- o -(e eye -eorally

    3. *le"ation (upraduction)is an u@ard ro-a-ion o -(e eye.

    4. Depreion (infraduction)is a do@n@ard ro-a-ion o -(e eye.

    ". 6ntorion (incicloduction)is a nasal ro-a-ion o -(e suerior

    or-ion o -(e $er-i'al 'orneal eridian.

    *. */torion (e/cycloduction)is a -eoral ro-a-ion o -(e

    suerior or-ion o -(e $er-i'al 'ornea eridian

    S(erring-ons la@

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    +he important term in monocular eye mo"ement

    'goni& -(e riary us'le o$ing -(e eye in a gi$en dire'-ion.

    Synergi& -(e us'le in -(e sae eye a'-s @i-( -(e agonis- -orodu'e a gi$en o$een-.

    'ntagoni& -(e us'le in -(e sae eye a'-s in -(e dire'-ionoosi-e -o -(a- o -(e agonis-

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    II. Binocular eye !o"e!ents : ?onsis-s o -@o -yes 5

    1. ,ersion %'onAuga-e bino'ular eye o$een-s) J

    -(e eyes o$e in -(e sae dire'-ion.

    /ig(- gae %de0-ro$ersion)

    Le- gae %le$o$ersion)

    #gae %sursu$ersion)

    =o@ngae %doursu$ersion)

    =e0-ro'y'lo$ersionLe$o'y'lo$ersion

    o!e muscleis used -o des'ribe -@o us'le %one in ea'( eye)

    -(a- are rie o$ers o -(eir rese'-i$e eyes in -(e gi$en

    osi-ion o gae

    Hering= la9

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    2. ,ergen'es %dis'onAuga-e bino'ular eye o$een-)

    ?on$ergen'e

    =i$ergen'e

    In'y'lo$ergen'e

    E0'y'lo$ergen'e

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    Terima Kasih