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DiaPark Test System for Early Diagnostics of Parkinson’s Disease DiaPark Razina Nigmatullina deputy CEO, LLC “Centre for the early diagnostics of the neurodegenerative diseases” Kazan, Russian Federation [email protected] +7 (927) 429 04 66

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DiaPark Test System for Early Diagnostics of

Parkinson’s Disease

DiaPark

Razina Nigmatullinadeputy CEO,LLC “Centre for the early diagnostics of the neurodegenerative diseases”Kazan, Russian [email protected]+7 (927) 429 04 66

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DiaPark Test System For Early Diagnostics Of Parkinson’s Disease 2

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%, Neurons

Neuronal cell deathTHE FIRST SYMPTOMS

ONSET OF THE DISEASE

Compensatory mechanisms

Development objectives:

Early diagnostics; Preventive treatment.

Limb tremor (tremor). Violation and stiffness of gait and speech

Trends:1. Shift towards younger patients, 15% of the patients are <40 years;2. The aging of the population. World population older than 60 years: in 2010 10%, 2040 25% of the population.

Caring for the growing number of patients is very expensive

Age

PARKINSON'S DISEASE IS INSIDIOUS: WHEN SYMPTOMS START APPEARING, IT IS IMPOSSIBLE TO CURE

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DiaPark Test System For Early Diagnostics Of Parkinson’s Disease 3

DiaPark – COST-EFFECTIVE EARLY WARNING SYSTEM

Test Kit:1. Immunological chips;2. Genetic chips;3. Electrophysiological tests

(EEG, ECG, EMG + program).

Cost-effective, mass, preventive care; Only selective diagnostics on expensive PET scan; Treatment of earlier stage disease effectively and cheaply.

Newly developed technology allows detection of Parkinson's disease for several years before the appearance of specific symptoms

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DiaPark Test System For Early Diagnostics Of Parkinson’s Disease 4

METHOD DiaPark IS ECONOMICALLY FEASIBLE FOR MASS DIAGNOSTICS

Radiation safetyThe survey of large population groups

Accuracy Price

DiaPark 85- 90% $150

PET 98-100% $6000

DiaPark$150 / patient

PET$6000 / patient

1 millionDiaPark

25 thousand PET

Improving the lives of millions and savings billions in money

??

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DiaPark Test System For Early Diagnostics Of Parkinson’s Disease 5

THE TEAM OF PROFESSIONALS

Ugrumov M.V. – CEO, CSO. International experience in

Neuroscience. More than 25 years of work in France, Japan, Germany and USA;

Author of 250 articles in leading international journals.

Nigmatullina R.R. - COO. International experience; Improving competencies

of technology commercialization «Fast trac Planning»;

Ph.D., professor.

Under the guidance of Academician M.V.Ugrumov team working from 2005 on the project   "Neurodegenerative diseases: development of preclinical diagnostics and preventive treatment "

Georgieva S.G. PhD., Slominsky P.A., PhD. - Examination of gene expression;Kudrin V.S. PhD., Pronina T.S. PhD.- Determination of monoamines and hormones;Obukhov Y.V., PhD. - Electrophysiology, mathematical processing, informatics technologies;

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DiaPark Test System For Early Diagnostics Of Parkinson’s Disease 6

YOU HAVE A CHANCE FOR INVESTING $2 MILLION IN DiaPark

1. The project is at the stage prototype development. Attracted $800 thousand of R&D funding through Federal Target Programs and grants; Grants and investments raised so far $200 thousand;

2. $2 million will be spent on: Clinical trials in Russia, Europe and the USA International patenting Product certification and registration Marketing Promotion of products on the world market

3. Output:Attracting investors for the next stage in the global market;Sale to a strategic investor (Amarantus BioSciences, Rainbow BioSciences, etc.).

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EARLY DIAGNOSTICS OF PARKINSON'S DISEASE MAY SAVE YOUR LIFE!

DiaPark:1. Saves human lives2. Saves money in healthcare 3. Offers You a great investment opportunity

Razina Nigmatullinadeputy CEO,

LLC “Centre for the early diagnostics of the neurodegenerative diseases”

Kazan, Russian [email protected]

+7 (927) 429 04 66