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The YL9100The YL9100SS HPLC HPLC

All your needs for semi-preparative applications

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YL9100S HPLC OverviewYL9100S HPLC Overview

Superior Performance

Greater Reliability

Excellent Usability

Serviceability and Easy Maintenance

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YL9100S HPLC – Features 1 YL9100S HPLC – Features 1

Higher performance solvent delivery pump - New designed carrier assembly and CAM - Improvement of precision

Better UV/Vis detector with new optic design - For better light intensity and higher sensitivity

New Detector – Photo Diode Array with excellent sensitivity Semi-prep flow cell is available

Superior PerformanceSuperior Performance

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YL9100S HPLC – Features 2 YL9100S HPLC – Features 2

Greater ReliabilityGreater Reliability

Improvement of System components - New designed main parts of Pump, Detectors and Column compartment with very robust materials

Innovative manufacturing process - Three step quality control and assurance system

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YL9100S HPLC – Features 3YL9100S HPLC – Features 3

Excellent UsabilityExcellent UsabilityExcellent UsabilityExcellent Usability

Intuitive, intelligent and powerful software - Easy control window for instruments of YL9100S HPLC - Harmonization Microsoft’s standards for accessing flies, reviewing data and reports, and other tasks - System Suitability Test with USP, EP and JP - Compliance with 21 CFR Part 11 - Diagnostics and Error detection Automation Perfectly of Analysis work - Startup, analysis operation, shut down, … , and to report generation

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YL9100S HPLC – Features 4YL9100S HPLC – Features 4

Serviceability and Easy MaintenanceServiceability and Easy MaintenanceServiceability and Easy MaintenanceServiceability and Easy Maintenance

Better long-life components - New designed the carrier, CAM, needle bearing, seals and belt (with polyurethane) for long-life time - New designed the Deuterium and Tungsten lamp guaranteed 2,000 hours - Semi-permanent peltier in the Column Compartment

Easy Maintenance - Easy replacement and pre-alignment of lamps - Easy replacement of sample cell assembly - Diagnostics procedure by software

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YL9100S HPLC – ModulesYL9100S HPLC – Modules

List of Modules

Degassing Module Pump Column Compartment UV/Vis Detector PDA Detector Refractive Index Detector Prep Autosampler Fraction Collector Chromatography Data System

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YL9100S HPLC – Modules -HDVMYL9100S HPLC – Modules -HDVM

YL9101S Vacuum Degasser- - No fluctuationNo fluctuation, shorten warming upshorten warming up

Number of channel : 2 CHs (option: 4 CHs)

Maximum degassing range: 50ml/min

High capacity of chamber: 62ml per channel

Safety & maintenance : Vacuum Error detection

Wide range of Line Voltage : 100-240VAC, ±10%, Wide range

Line frequency : 50/60Hz, ±5%

Power consumption : 50W

YL9101S Vacuum Degasser will be available by JuneYL9101S Vacuum Degasser will be available by June

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YL9100S HPLC – Modules -HDVMYL9100S HPLC – Modules -HDVM

Helium Degassing Valve Module

Number of channel : 4 CHs

Degassing type: Helium gas

(This module is required a He gas cylinder)

Wide range of Line Voltage : 100-240VAC

Line frequency : 50/60Hz

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YL9100S HPLC – Modules -VDYL9100S HPLC – Modules -VD

Vacuum Degasser – Stand-alone type

Number of channel : 2 CHs

Maximum degassing range: 50ml/min

Wide range of Line Voltage : 100-240VAC

Line frequency : 50/60Hz

Power consumption : 46W

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YL9100S HPLC – Modules – YL9100S HPLC – Modules – PumpPump

YL9110S Quaternary Pump

YL9111S Binary Pump

YL9112S Isocratic Pump

New design of mechanical parts of pumps

Compressibility Compensation technology

Semi-automatic Prime/Purge

Built-in Leak sensor

Wide flow range by each check valve with two balls

Ultra robust carrier, bearing, belt, etc

For isolation and purification of preparative HPLC

Flow rate: max. 50ml/min

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YL9100S HPLC – Modules – YL9100S HPLC – Modules – BPBP

YL9111S Binary Pump (Recommended for Semi-prep)

A New Pump for higher throughput and reproducibility

The best pump for High Pressure Gradient System

Built-in Large capacity static mixer

X2 Parallel dual-plunger

Attractive price compared to QP

Ideal pump for semi-prep application

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YL9100S HPLC – Modules – YL9100S HPLC – Modules – QP/IPQP/IP

YL9110S Quaternary Pump

Attached 4-way mixing valve to QP

YL9112S Isocratic Pump

Improved Isocratic Pump with parallel dual-plunger

Easy upgraded from IP to QP

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YL9100S HPLC – Modules -CCYL9100S HPLC – Modules -CC

YL9130S Column Compartment- - Powerful temperature controlPowerful temperature control

The best temperature precision: ±0.05°C

Powerful Cooling is the standard: down to 4 °C

Preheating available

Semi-automatic injector/Switching valve: up to 1(option)

Column capacity: 300mm – 2ea

Leak sensor

40 steps programming

Column OD: up to 28mm

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YL9100S HPLC – Modules -UVDYL9100S HPLC – Modules -UVD

YL9120S UV/Vis Detector- - Excellent sensitivityExcellent sensitivity

New designed Optic structure: Seya-Namioka

New Blazed Holographic Concave Grating

Excellent Data acquisition rate: up to 50 Hz

Long-life D2 lamp, 2000 hours guarantee

Advanced band width: 5.5 nm

Excellent Sensitivity: <±0.5 x 10-5 AU at 254nm

Integrated cell and slit assembly

Greater cooling of the lamp’s thermal environment

Optimal cell volume and path length for semi-preparative purpose

Leak sensor

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YL9100S HPLC – Modules -UVDYL9100S HPLC – Modules -UVD

YL9120S UV/Vis Detector

What is the Seya-Namioka monochromator

- To attach New Blazed Holographic Concave Grating

- Extremely low stray light

- Highest light intensity

- Reduced astigmatism

- Very compact design and size

- More serviceability

- High performance beam splitter

- New designed an integrated cell+slit assembly

- Excellent band width, 5.5nm

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YL9100S HPLC – Modules -PDAYL9100S HPLC – Modules -PDA

YL9160S PDA Detector

Optimum wavelength resolution: 1,024 diodes

Wide range from 190 to 950 nm

Highest Sensitivity

<±1.0 x 10-5 AU at 254nm, 2 sec rise time

<±2.0 x 10-5 AU at 254nm, 1 sec rise time

Fast data acquisition: 50 Hz

Greatest drift level

<2.0 x 10-4 AU/h at 254nm, Baseline correction

<1.0 x 10-3 AU/h at 254nm

- Highest Sensitivity- Highest Sensitivity

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YL9100S HPLC – Modules -RIDYL9100S HPLC – Modules -RID

YL9170S RID

- For universal detection- For universal detection

RI Range : 1.00 ~ 1.75 RIU

Noise : < ±1.0 x 10-7 RIU

Linear dynamic range : 0-20000 μRIUFlow rate range : 1 ~ 50.0 ml/min

Cell pressure : 6 kg/cm2(84 psi)

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YL9100S HPLC – Modules -ASYL9100S HPLC – Modules -AS

YL9150 Autosampler – Prep Autosampler

- Fully automated work- Fully automated work

Sample capacity: 24 vials(10ml for prep)

Sample loop: 10ml

Injection: partial loop

RSD ≤ 1.0% for partial loopfill.

Carry-over < 0.1%

Option: Built-in Peltier cooling (4oC ~ ambient –3oC)

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YL9100S HPLC – Modules -FCYL9100S HPLC – Modules -FC

Fraction Collector – FC204/203B

A stand-alone operation using time, drop or peak based collection

Collect fractions by time, drop or peak with ease; manual collection is also available

Simply set the time or number of drops, press START and walk away

Drop counting: Up to 9,999 drops per fraction Maximum rate: 20 drops/sec

HELP, YES, NO, 0-9 numeric hard keys/four soft keys

2-line, 24-character display on backlit LCD

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YL9100S HPLC – Modules -CDSYL9100S HPLC – Modules -CDS

YL-Clarity CDS

- Intelligent and Powerful Chromatography Data Station- Intelligent and Powerful Chromatography Data Station

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MeasuringFour Instruments up to 12 detectors.

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Post-runAutomatically displays, prints, exports and starts other programs

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YL9100S HPLC – Modules -CDSYL9100S HPLC – Modules -CDS

3Column performanceMethod validationBy USP, EP and JP

4User accountsSets up access rights and passwords

5Audit trailRecords selected events and operations into a special file.

6Electronic signatureEach chromatogram can be signed electronically.

7Networked SolutionClarity files can be accessed from networked computers using Clarity Offline software.

8Great CompatibilityWindow XP/2000.Window Me/98, and Window Vista (32bit) is available

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YL9100S HPLC – Modules -CDSYL9100S HPLC – Modules -CDS

YL-Clarity CDS

Perfectly compliance with 21CFR Part 11

GPC option available

System Suitability Test option available(Method validation)

PDA module option available: 3-D data analysis

Software Validation option available: Software OQS/W validation kit