1 peripher a alnerve genetherapy periph gen innovative solutions for neurological disorders

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1 Peripheral Nerve Gen e Therapy Periph Gen Innovative solutions for neurological disorders www.PeriphaGen.com

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Page 1: 1 Peripher a alNerve GeneTherapy Periph Gen Innovative solutions for neurological disorders

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Peripheraal NerveGene Therapy

PeriphGen

Innovative solutions for neurological disorders

www.PeriphaGen.com

Page 2: 1 Peripher a alNerve GeneTherapy Periph Gen Innovative solutions for neurological disorders

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How NET Drugs Treat Pain

Traditional Pain Drugs NET Pain Drugs

Dry mouth

Muscle aches & weakness

GI problemsConstipation

Blurred vision Dizziness, drowsiness, cognitive changes

Swollen hands &

feet

Mild Pain

Relief

Better Pain Relief

Monthly skin

delivery

Daily systemicoral drug

Drug spreads throughout the body

Net drug localized to treated nerves

No systemic side effects

Pain signal to brain

Click to start animation

Injury

Click for next animation

Page 3: 1 Peripher a alNerve GeneTherapy Periph Gen Innovative solutions for neurological disorders

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How NET Drugs Treat Neuropathy

Chemotherapy alone With NET CIPN Drug

Prophylactic skin delivery

Dose-dependent chemotherapy induced peripheral neuropathy

(CIPN)

Peripheral nerves protected

Chemotherapy course

Chemotherapy course

Pain, dysethesia,paresthesia

Damage to nerve fibers

Reduced course

Reduced survival

Full course

Increased survival

No damage to nerve fibers