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Novel Drug Delivery Systems,Preparation techniques

دکتر رسول دينارونداستاد داروسازي، دانشگاه علوم

پزشکي تهران

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ويژگي پليمرها

قابليت اختالط باساير مواد

سادگي ساختسازگاري زيستيساختمان شبکه ايقابليت تنظيم تراواييپايداريشکل پذيري

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Polymeric DDS devices

Matrix

Reservoir

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Polymeric DDS devices

Particulate systems Nanoparticles

Nanocapsules Nanospheres

Microparticles Microspheres Microcapsules

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Polymeric DDS devices

Films Membrane

s Fibers Rods Beads Discs Cylinders

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PLA Cylinder for naltrexone delivery

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Device types

Reservoir devices

Matrix devices Particles

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Fabrication techniques

Membrane preparation Homogeneous

membranes Solution casting Spin casting mold Melt formed method Polymerisation casting

Porous membranes Phase separation method Nucleation track method Expanded film method

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Membrane preparation

Homogeneous membranes

Solution casting Spin casting Melt forming

Porous membranes Phase separation

Non-solvent Evaporation Salting out Thermal gelation Watering out

Physical methods Nucleation track Elongation

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Reservoir systems

Laminated devices Sandwich fabrication

Adhesive Solvent Melt compression

Cylindrical devices Melt extrusion Injection molding Spin casting Solvent casting

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Monolithic devices

Solvent casting Melt casting Extrusion Particle compression Polymerisation casting (hydrogels)

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Microparticles

Coacervation Solvent

evaporation Interfacial

polymerisation Spray drying

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