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1. GI Pharmacology - Acid Suppression: Antacids, Acid Suppressa... 2. Objectives Tufts OpenCourseWare © 2007 Tufts University GI Pharmacology I: Acid Suppression OCW: Gastrointestinal Pathophysiology (P. Abourjaily) Page - 1

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Page 1: 1. GI Pharmacology - Acid Suppression: Antacids, Acid ...ocw.tufts.edu/data/48/598665.pdf · 1. GI Pharmacology - Acid Suppression: Antacids, Acid Suppressa... 2. Objectives Tufts

1. GI Pharmacology - Acid Suppression: Antacids, Acid Suppressa...

2. Objectives

Tufts OpenCourseWare © 2007 Tufts University

GI Pharmacology I: Acid Suppression

OCW: Gastrointestinal Pathophysiology (P. Abourjaily) Page - 1

Page 2: 1. GI Pharmacology - Acid Suppression: Antacids, Acid ...ocw.tufts.edu/data/48/598665.pdf · 1. GI Pharmacology - Acid Suppression: Antacids, Acid Suppressa... 2. Objectives Tufts

3. Physiology of Gastric Acid Secretion

4. Physiology of Gastric Acid Secretion

Tufts OpenCourseWare © 2007 Tufts University

GI Pharmacology I: Acid Suppression

OCW: Gastrointestinal Pathophysiology (P. Abourjaily) Page - 2

Page 3: 1. GI Pharmacology - Acid Suppression: Antacids, Acid ...ocw.tufts.edu/data/48/598665.pdf · 1. GI Pharmacology - Acid Suppression: Antacids, Acid Suppressa... 2. Objectives Tufts

5. Physiology of Gastric Acid Secretion

6. Gastric Defense

Tufts OpenCourseWare © 2007 Tufts University

GI Pharmacology I: Acid Suppression

OCW: Gastrointestinal Pathophysiology (P. Abourjaily) Page - 3

Page 4: 1. GI Pharmacology - Acid Suppression: Antacids, Acid ...ocw.tufts.edu/data/48/598665.pdf · 1. GI Pharmacology - Acid Suppression: Antacids, Acid Suppressa... 2. Objectives Tufts

7. Drugs For Control of Gastric Acidity

8. Antacids

Tufts OpenCourseWare © 2007 Tufts University

GI Pharmacology I: Acid Suppression

OCW: Gastrointestinal Pathophysiology (P. Abourjaily) Page - 4

Page 5: 1. GI Pharmacology - Acid Suppression: Antacids, Acid ...ocw.tufts.edu/data/48/598665.pdf · 1. GI Pharmacology - Acid Suppression: Antacids, Acid Suppressa... 2. Objectives Tufts

9. Antacids

10. Antacids

Tufts OpenCourseWare © 2007 Tufts University

GI Pharmacology I: Acid Suppression

OCW: Gastrointestinal Pathophysiology (P. Abourjaily) Page - 5

Page 6: 1. GI Pharmacology - Acid Suppression: Antacids, Acid ...ocw.tufts.edu/data/48/598665.pdf · 1. GI Pharmacology - Acid Suppression: Antacids, Acid Suppressa... 2. Objectives Tufts

11. Antacid Examples

12. Cytoprotectants

Tufts OpenCourseWare © 2007 Tufts University

GI Pharmacology I: Acid Suppression

OCW: Gastrointestinal Pathophysiology (P. Abourjaily) Page - 6

Page 7: 1. GI Pharmacology - Acid Suppression: Antacids, Acid ...ocw.tufts.edu/data/48/598665.pdf · 1. GI Pharmacology - Acid Suppression: Antacids, Acid Suppressa... 2. Objectives Tufts

13. Physiology of Gastric Acid Secretion

14. Cytoprotectants

Tufts OpenCourseWare © 2007 Tufts University

GI Pharmacology I: Acid Suppression

OCW: Gastrointestinal Pathophysiology (P. Abourjaily) Page - 7

Page 8: 1. GI Pharmacology - Acid Suppression: Antacids, Acid ...ocw.tufts.edu/data/48/598665.pdf · 1. GI Pharmacology - Acid Suppression: Antacids, Acid Suppressa... 2. Objectives Tufts

15. Sucralfate

16. Sucralfate

Tufts OpenCourseWare © 2007 Tufts University

GI Pharmacology I: Acid Suppression

OCW: Gastrointestinal Pathophysiology (P. Abourjaily) Page - 8

Page 9: 1. GI Pharmacology - Acid Suppression: Antacids, Acid ...ocw.tufts.edu/data/48/598665.pdf · 1. GI Pharmacology - Acid Suppression: Antacids, Acid Suppressa... 2. Objectives Tufts

17. Cytoprotectants

18. Misoprostol

Tufts OpenCourseWare © 2007 Tufts University

GI Pharmacology I: Acid Suppression

OCW: Gastrointestinal Pathophysiology (P. Abourjaily) Page - 9

Page 10: 1. GI Pharmacology - Acid Suppression: Antacids, Acid ...ocw.tufts.edu/data/48/598665.pdf · 1. GI Pharmacology - Acid Suppression: Antacids, Acid Suppressa... 2. Objectives Tufts

19. Misoprostol

20. Cytoprotectants

Tufts OpenCourseWare © 2007 Tufts University

GI Pharmacology I: Acid Suppression

OCW: Gastrointestinal Pathophysiology (P. Abourjaily) Page - 10

Page 11: 1. GI Pharmacology - Acid Suppression: Antacids, Acid ...ocw.tufts.edu/data/48/598665.pdf · 1. GI Pharmacology - Acid Suppression: Antacids, Acid Suppressa... 2. Objectives Tufts

21. Bismuth subsalicylate

22. H2-Receptor Antagonists

Tufts OpenCourseWare © 2007 Tufts University

GI Pharmacology I: Acid Suppression

OCW: Gastrointestinal Pathophysiology (P. Abourjaily) Page - 11

Page 12: 1. GI Pharmacology - Acid Suppression: Antacids, Acid ...ocw.tufts.edu/data/48/598665.pdf · 1. GI Pharmacology - Acid Suppression: Antacids, Acid Suppressa... 2. Objectives Tufts

23. Physiology of Gastric Acid Secretion

24. H2-Receptor Antagonists

Tufts OpenCourseWare © 2007 Tufts University

GI Pharmacology I: Acid Suppression

OCW: Gastrointestinal Pathophysiology (P. Abourjaily) Page - 12

Page 13: 1. GI Pharmacology - Acid Suppression: Antacids, Acid ...ocw.tufts.edu/data/48/598665.pdf · 1. GI Pharmacology - Acid Suppression: Antacids, Acid Suppressa... 2. Objectives Tufts

25. H2-Receptor Antagonists

26. H2-Receptor Antagonists

Tufts OpenCourseWare © 2007 Tufts University

GI Pharmacology I: Acid Suppression

OCW: Gastrointestinal Pathophysiology (P. Abourjaily) Page - 13

Page 14: 1. GI Pharmacology - Acid Suppression: Antacids, Acid ...ocw.tufts.edu/data/48/598665.pdf · 1. GI Pharmacology - Acid Suppression: Antacids, Acid Suppressa... 2. Objectives Tufts

27. H2-Receptor Antagonists

28. H2-Receptor Antagonists

Tufts OpenCourseWare © 2007 Tufts University

GI Pharmacology I: Acid Suppression

OCW: Gastrointestinal Pathophysiology (P. Abourjaily) Page - 14

Page 15: 1. GI Pharmacology - Acid Suppression: Antacids, Acid ...ocw.tufts.edu/data/48/598665.pdf · 1. GI Pharmacology - Acid Suppression: Antacids, Acid Suppressa... 2. Objectives Tufts

29. Proton Pump Inhibitors

30. Physiology of Gastric Acid Secretion

Tufts OpenCourseWare © 2007 Tufts University

GI Pharmacology I: Acid Suppression

OCW: Gastrointestinal Pathophysiology (P. Abourjaily) Page - 15

Page 16: 1. GI Pharmacology - Acid Suppression: Antacids, Acid ...ocw.tufts.edu/data/48/598665.pdf · 1. GI Pharmacology - Acid Suppression: Antacids, Acid Suppressa... 2. Objectives Tufts

31. Proton Pump Inhibitors

32. Proton Pump Inhibitors

Tufts OpenCourseWare © 2007 Tufts University

GI Pharmacology I: Acid Suppression

OCW: Gastrointestinal Pathophysiology (P. Abourjaily) Page - 16

Page 17: 1. GI Pharmacology - Acid Suppression: Antacids, Acid ...ocw.tufts.edu/data/48/598665.pdf · 1. GI Pharmacology - Acid Suppression: Antacids, Acid Suppressa... 2. Objectives Tufts

33. Proton Pump Inhibitors

34. Proton Pump Inhibitors

Tufts OpenCourseWare © 2007 Tufts University

GI Pharmacology I: Acid Suppression

OCW: Gastrointestinal Pathophysiology (P. Abourjaily) Page - 17

Page 18: 1. GI Pharmacology - Acid Suppression: Antacids, Acid ...ocw.tufts.edu/data/48/598665.pdf · 1. GI Pharmacology - Acid Suppression: Antacids, Acid Suppressa... 2. Objectives Tufts

35. Proton Pump Inhibitors

36. Sites of Drug Action

Tufts OpenCourseWare © 2007 Tufts University

GI Pharmacology I: Acid Suppression

OCW: Gastrointestinal Pathophysiology (P. Abourjaily) Page - 18

Page 19: 1. GI Pharmacology - Acid Suppression: Antacids, Acid ...ocw.tufts.edu/data/48/598665.pdf · 1. GI Pharmacology - Acid Suppression: Antacids, Acid Suppressa... 2. Objectives Tufts

37. Prokinetic Agents

38. Physiology of Gastric Motility

Tufts OpenCourseWare © 2007 Tufts University

GI Pharmacology I: Acid Suppression

OCW: Gastrointestinal Pathophysiology (P. Abourjaily) Page - 19

Page 20: 1. GI Pharmacology - Acid Suppression: Antacids, Acid ...ocw.tufts.edu/data/48/598665.pdf · 1. GI Pharmacology - Acid Suppression: Antacids, Acid Suppressa... 2. Objectives Tufts

39. Therapeutic Application

40. Urease Breath Test for H. pylori

Tufts OpenCourseWare © 2007 Tufts University

GI Pharmacology I: Acid Suppression

OCW: Gastrointestinal Pathophysiology (P. Abourjaily) Page - 20

Page 21: 1. GI Pharmacology - Acid Suppression: Antacids, Acid ...ocw.tufts.edu/data/48/598665.pdf · 1. GI Pharmacology - Acid Suppression: Antacids, Acid Suppressa... 2. Objectives Tufts

41. Helicobacter pylori

42. Helicobacter pylori

Tufts OpenCourseWare © 2007 Tufts University

GI Pharmacology I: Acid Suppression

OCW: Gastrointestinal Pathophysiology (P. Abourjaily) Page - 21

Page 22: 1. GI Pharmacology - Acid Suppression: Antacids, Acid ...ocw.tufts.edu/data/48/598665.pdf · 1. GI Pharmacology - Acid Suppression: Antacids, Acid Suppressa... 2. Objectives Tufts

43. Helicobacter pylori

Tufts OpenCourseWare © 2007 Tufts University

GI Pharmacology I: Acid Suppression

OCW: Gastrointestinal Pathophysiology (P. Abourjaily) Page - 22