CIRCOVAC benefits on reproductive parameters

Thaïs VILA, DVMMERIAL – Swine Technical Director EMEA

Context

• A lot of field experiences published evidenced the benefits of PCV2 sow vaccination on reproductive parameters

Farm A B C

Nb sows 250 80 146

Nb vaccinated sows 89 32 41

Nb control sows 46 21 39

Material and method

• Good Clinical Practice• Blinded, controlled, randomised trial• 3 farrow to finish German farms

Material and method

• 3 farrow to finish German farms• PCVD confirmed

– Mortality wean to finish: 10% – Lesions at necropsy– Serologies PCV2 – Histopathological lesions on lymph nodes

Material and method

• CIRCOVAC vaccination (2 ml/dose)– 2 injections before the 1st farrowing

• V1: 5-6 weeks before farrowing 1• V2: 2-3 weeks before farrowing 1

– 1 booster vaccination • 2-3 weeks before 2nd farrowing

Results

Global mortality in offsprings

Vaccinated group: 8.7%Control group: 9.5%

Mortality related to PMWSLesion score at necropsyPCRInguinal lymph nodes lesions

Low incidence of PCV2 infection (similar between groups)

Serology and viremia in sows and offsprings

Increase of serum antibodies level in sows, gilts and offspring provided by vaccination

CIRCOVAC Control

N Min Max N Min Max

Cycle 1 155 10.6 2.4 2.0 18.0 54 10.2 2.7 1.0 15.0

Cycle 2 124 11.5* 2.1 6.0 19.0 40 10.1* 3.4 1.0 14.0

* p=0.007

Results: live born piglets

+ 1.4 piglet / sow

CIRCOVAC Control

N Min Max N MinMax

Cycle 1 155 9.2 2.4 1.0 17.0 54 8.9 2.3 1.0 12.0

Cycle 2 124 9.8* 1.8 3.0 14.0 40 8.6* 3.3 1.0 13.0

* p=0.027

Results: weaned piglets/sow

+ 0.7 piglet / sow+ 1.6 weaned / sow / year

Conclusion

• Comparative, controlled, randomised trial

• 370 farrowings• Significant improvement

+ 1.6 weaned piglets / sow / year

• Confirms proof from the field

CIRCOVAC benefits at all stages

Thank you!