01 cellular introduction ma

26
Instructor: Marco Atzori Cellular Neuroscience

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Page 1: 01 cellular introduction ma

Instructor: Marco Atzori

Cellular Neuroscience

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Cellular Neuroscience

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Neurons and glias are very specializedtype of cells with basicallythe same intracellularorganelles asall othercells

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Control of body functions in simple to complex animals

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100 Billion Neurons

10,000 contacts per cell

One Thousand

Trillion Synapses

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Many techniquesare used for understandingthe nervous system

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Genetics

Knock-out, knock-in, antisense probes, etc.

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Electrophysiology

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Biochemistry and Neurochemistry

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Animal Models

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Anatomy and neurocytology

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Anatomy terminology

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Major anatomic divisions

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Fro

m S

kin

to B

rain

Cortex

Midbrain

Medulla

Spinal Cord

Finger

Touch Cortex

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Org

aniz

ed M

ap

of th

e E

ntir

e B

ody

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Stroke Damage Helps Us Understand Brain Function

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Huge variety of neuronal typesif compared to other organs such as:

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the kidney or

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the liver

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The same neurons display different behavior in different conditions